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Imperial College London


Life on Mars theory boosted by new methane study

Scientists have ruled out meteorites as a source of methane on Mars, raising hopes that the gas might be generated by life on the red planet. Methane levels are replenished by an unknown source, with two plausible theories remaining: microorganisms producing methane as a by-product or reactions between volcanic rock and water.

SourceImperial College London·JournalEarth and Planetary Science Letters·DateDec 8, 2009

Research reveals exactly how coughing is triggered by environmental irritants

Researchers have identified the reaction inside the lungs that can trigger coughing when exposed to certain air pollutants and irritants. The study found that switching on receptor proteins called TRPA1 on nerve endings in the lungs triggers a cough reflex, which could potentially be treated by blocking these receptors.

SourceImperial College London·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateNov 23, 2009

HIV vaccine failure probably caused by virus used, says new research

Researchers found that people who had previously built up immunity to the adenovirus used in the trial had a higher risk of infection with HIV after receiving the vaccine. The study suggests that other adenovirus-based vaccines, such as those for tuberculosis and malaria, may also be at risk due to the same immune system reaction.

SourceImperial College London·JournalProceedings of the National Academy of Sciences·DateNov 16, 2009

Drug shrinks lung cancer tumors in mice

A new study published in Cancer Research found that a potential drug for lung cancer eliminated tumours in 50% of mice and stopped growth and resistance to treatment. The researchers are planning to take the drug into clinical trials to establish its effectiveness for patients with small cell lung cancer.

SourceImperial College London·JournalCancer Research·DateNov 10, 2009

Urine samples could be used to predict responses to drugs, say researchers

Researchers from Imperial College London and Pfizer Research and Development found that urine samples can be used to predict how individuals will respond to certain drugs. The study looked at acetaminophen levels in urine before and after consumption and found that compounds like para-cresol sulphate were indicators of drug metabolism.

SourceImperial College London·JournalProceedings of the National Academy of Sciences·DateAug 10, 2009

Human nose too cold for bird flu, says new study

Research suggests that avian influenza viruses struggle to grow and spread in the human nose due to its cooler temperature, making it less likely to cause respiratory illness. The study also found that mutated viruses with proteins from avian influenza viruses are unlikely to thrive at human nose temperatures.

SourceImperial College London·JournalPLOS Pathogens·DateMay 14, 2009

Young adults at future risk of Alzheimer's have different brain activity, says study

A new study by scientists from Imperial College London and University of Oxford found that young adults with a genetic variant associated with Alzheimer's Disease exhibit changes in brain activity decades before any symptoms appear. The researchers used functional Magnetic Resonance Imaging (fMRI) to compare the brains of healthy young...

SourceImperial College London·JournalProceedings of the National Academy of Sciences·DateApr 6, 2009