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Penn State


Education slowing AIDS in sub-Saharan Africa

Increased schooling across sub-Saharan Africa may lower new HIV infections among younger adults, contradicting previous views of education as an AIDS risk factor. Formal education appears to reduce the risk of HIV infections by up to 34 percent in some countries.

Motor proteins may be vehicles for drug delivery

Researchers have discovered that motor proteins can be engineered for efficient cargo transport, potentially leading to targeted cancer treatment. By altering the function of these proteins, scientists aim to develop new drugs that inhibit kinesin activity during cell division, slowing tumor growth.

SourcePenn State·JournalCurrent Biology·DateMar 20, 2009

West Antarctic ice comes and goes, rapidly

Researchers modeled West Antarctic ice sheet's past movements and found it collapsed and regrew multiple times due to ocean warming. The study uses deep sea oxygen isotope ratios to deduce Antarctic temperature changes and suggests the ice sheet may collapse if ocean temperatures warm sufficiently.

SourcePenn State·JournalNature·DateMar 18, 2009

Researchers predict click-through behavior in Web searches

A study by Penn State researchers identified nine factors that can help predict future click-through rates, including number of records in a search and browser type. The positive factors had five effects, while four had negative effects, with user intent having no significant impact on predicting click-throughs.

SourcePenn State·JournalJournal of the American Society for Information Science and Technology·DateMar 11, 2009

Sunlight turns carbon dioxide to methane

Researchers at Penn State developed a solar-powered process converting carbon dioxide to methane using titania nanotubes, achieving a 20-times higher yield than previous attempts. The method uses dual catalysts coated on the nanotubes, resulting in significant hydrocarbon production.

SourcePenn State·JournalNano Letters·DateMar 5, 2009

Vegetable-based drug could inhibit melanoma

Researchers have developed a potent drug against melanoma by combining compounds from green vegetables with selenium. The new compound, isoselenocyanate, targets the Akt3 protein and reduces tumor growth by 50-60%, showing potential for low-toxicity treatment.

SourcePenn State·JournalClinical Cancer Research·DateMar 1, 2009

Team-based diabetes care fetches more value for dollar

A recent study found that team-based diabetes care improves health outcomes for Medicaid patients, including significant reductions in systolic blood pressure, body mass index, and hemoglobin A1C. However, the study suggests that this approach does not result in lower treatment costs under Medicare and Medicaid.

SourcePenn State·JournalDiabetes Care·DateFeb 26, 2009

Ad click-through rate lower than previously thought

Researchers found ad clicks on Dogpile.com to be only 15% of total interactions, with 35% of queries yielding no clicks. The study challenges previous reports of a 30% ad click-through rate and suggests advertisers can leverage alternative forms of keyword advertising.

SourcePenn State·JournalInternational Journal of Internet Marketing and Advertising·DateFeb 25, 2009

Climate change may alter malaria patterns

Climate change is altering malaria patterns due to daily temperature fluctuations, which can affect the incubation period of malaria parasites in mosquitoes. This can lead to changes in transmission rates, with warmer temperatures potentially increasing the risk of infection.

Artificial cells, simple model for complex structure

Scientists develop a simple model for complex cell structure by creating artificial cells with molecular crowding and heterogeneity. The system mimics the behavior of proteins and nucleic acids in living cells, allowing researchers to study the effects of macromolecular crowding on chemical reactions.

Scientists find new way to produce hydrogen

Researchers at Penn State University have discovered a way to produce hydrogen by exposing aluminum clusters to water, leveraging their unique geometric structures. The process enables the production of hydrogen gas without heat or energy input, opening up new possibilities for clean energy applications.

SourcePenn State·JournalScience·DateJan 22, 2009

Off the shelf maps help mitigate volcanic hazards

A team of volcanologists developed a new program to quickly and accurately predict areas at high risk for lethal hazards from volcanic eruptions. The program uses existing GIS data to create maps that outline potential surge damage, enabling decision-makers to evacuate or put people on high alert.

SourcePenn State·JournalBulletin of Volcanology·DateJan 21, 2009

Easy assembly of electronic biological chips

Researchers create handheld device to recognize and report on environmental or medical compounds using biologically tagged nanowires and integrated circuit chips. The method allows for accurate placement of nanowires with less than a micron accuracy, enabling simultaneous detection of different pathogens or diseases.

SourcePenn State·JournalScience·DateJan 15, 2009

Hair of Tasmanian tiger yields genes of extinct species

A team of scientists has successfully sequenced the genes of the Tasmanian Tiger from its hair, revealing insights into mammal extinction and potential ways to prevent it. The study also opens up new possibilities for analyzing museum specimens and could potentially lead to the revival of extinct species.

SourcePenn State·JournalGenome Research·DateJan 12, 2009

Tiny capsules deliver

Researchers at Penn State have developed tiny particle syringes that can deliver specific drugs to diseased cells, reducing toxins in the body. The microcapsules are flexible and can be filled with a variety of substances, making them a potential solution for targeted treatment.

SourcePenn State·JournalSoft Matter·DateJan 12, 2009

Modified plants may yield more biofuel

Researchers have developed a genetic modification that modifies the connections in lignin, making it easier to break down and access cellulose for ethanol production. The modified plants show increased sugar yields without compromising plant strength or lignin content.

Properties of unusual virus revealed in research

A team of researchers has discovered how the N4 phage injects its own RNA polymerase into E. coli bacterial cells, enabling it to create new proteins without host help. The unique property allows for potential therapeutic applications in killing E. coli bacteria.

SourcePenn State·JournalMolecular Cell·DateDec 8, 2008

Selenium may slow march of AIDS

Researchers at Penn State have discovered that increasing selenium levels in human blood cells can reduce the multiplication of the AIDS virus. By targeting a specific protein called Tat, selenium can slow down viral replication, with results showing a 10-fold decrease.

SourcePenn State·JournalJournal of Biological Chemistry·DateNov 28, 2008

Speed matters for ice-shelf breaking

Scientists have derived a simple law to predict where icebergs will calve off from parent ice sheets. The rate of spreading, width, and thickness of the ice shelf are key factors in this process, accounting for most observed variability.

SourcePenn State·JournalScience·DateNov 27, 2008

Route to obesity passes through tongue

A Penn State study found that obese rats are less sensitive to sweet tastes and prefer sweeter foods due to a weakened response to weak concentrations, leading to a vicious circle of overeating and sugar cravings. The research suggests that the brain's reward center is affected by the increased consumption of sugary foods.

SourcePenn State·JournalJournal of Neurophysiology·DateNov 26, 2008

Scientists shed light on evolution of gene regulation

Researchers at Penn State have discovered that not all DNA segments bound to the GATA1 protein are conserved across mammals, challenging previous assumptions. They found that 45% of these segments retain their identical form in other species, suggesting purifying selection maintains most regulatory regions.

SourcePenn State·JournalGenome Research·DateNov 24, 2008

Sea level rise alters bay's salinity

Researchers from Penn State and University of Maryland studied Chesapeake Bay's salinity changes due to sea-level rise. They found an increasing trend in salinity, supporting the hypothesis that climate change is impacting the Bay's ecosystem.

Scientists sequence woolly-mammoth genome

The researchers sequenced the mammoth's nuclear genome, yielding information about its evolution and extinction. They found that woolly mammoths separated into two groups around two million years ago and eventually became genetically distinct sub-populations.

SourcePenn State·JournalNature·DateNov 19, 2008

Global warming link to amphibian declines in doubt

Researchers found that global warming may not be the primary cause of widespread amphibian declines, contradicting previous widely-held views. The study suggests alternative factors, such as a fungal infection and pesticide use, may be driving these extinctions.

SourcePenn State·JournalProceedings of the National Academy of Sciences·DateNov 12, 2008

IT outsourcing could benefit rural hospitals, researchers find

A case study conducted by Penn State researchers found that rural hospitals can benefit financially and operationally by sharing an IT infrastructure with larger hospitals in the same area. The partnership allows smaller hospitals to afford comprehensive IT systems at a lower cost, while also benefiting from shared IT staff and expertise.

SourcePenn State·JournalJournal of the American Medical Informatics Association·DateOct 23, 2008

Where Hispanics live in the US may change over time

A study finds that White and Black Hispanics in the US are more likely to integrate with non-Hispanic Whites and African Americans, while Mexicans show consistent generational assimilation. This trend suggests a decrease in racial segregation and an increase in integration over time.

SourcePenn State·JournalAmerican Sociological Review·DateOct 17, 2008

Scientists use light to control proteins

Researchers at Penn State and the University of Texas Southwestern Medical Center have discovered a way to control certain proteins using light. The team's hybrid protein was engineered to respond to light, increasing or decreasing enzyme activity depending on the illumination, offering new possibilities for treating diseases.

SourcePenn State·JournalScience·DateOct 16, 2008

Origin of Alps-size Antarctic mountain range unknown

A U.S.-led team of scientists will use advanced radar and seismic tools to explore the Gamburtsev Mountain range in Antarctica. They hope to determine how this massive mountain range formed, defying geological understanding, and whether it played a role in shaping the East Antarctic Ice Sheet.