A study has identified mimecan and TXNDC5 as potential biomarkers for early detection of colorectal cancer. The research found that these proteins are differentially expressed in colorectal adenoma, a precursor lesion to the disease.
A novel 3D cell culture model has been developed to study the selective uptake of nanoparticles in brain tumors. The model uses a combination of tumor aggregates and normal brain tissue slices, allowing researchers to investigate tumor cell invasion into brain tissue.
Researchers have discovered that attaching polymeric nanoparticles to red blood cells increases their in vivo lifetime. This breakthrough could lead to new treatments for cancer, blood clots, and heart disease by providing sustained release of drugs.
A new study by Dr. Guyden and colleagues reveals that thymic nurse cells regulate T cell development by selecting thymocytes to live or die. The findings suggest that these cells have the capacity to internalize both non-functional and positively selected thymocytes, leading to a revised understanding of their function.