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Science News for August 23, 2007


OSU 3-for-3 in NSF competition

Oklahoma State University has received $1.5M in NSF grants to acquire two new instruments: a field emission environmental scanning electron microscope and an LTQ mass spectrometer. These instruments will enhance research capabilities in areas of interest to industry, government, and other universities.

New cancer weapon: nuclear nanocapsules

Researchers at Rice University have developed a way to package radioactive particles inside DNA-sized carbon tubes to target tiny tumors. The alpha-emitting nanocapsules are designed to deliver a single, direct hit to cancer cells, making them potentially more effective than traditional beta-particle radiation.

SourceRice University·JournalSmall·DateAug 23, 2007

Separating the brain's 'bad' from 'good' iron

Researchers have created 'pro-chelators' that can selectively bind to potentially destructive forms of iron in the brain, reducing oxidative stress and cell damage associated with these diseases. The iron-binding agents are designed to target only harmful iron species, allowing benign forms to carry out vital functions.

Toxic shock: immune system's anthrax link

Researchers at Monash University uncover a molecular arms race between bacteria and the human immune system, revealing perforins as key players in defense against bacterial toxins. The discovery could lead to new ways to fight disease, including infectious diseases and transplantation rejection.

SourceMonash University·JournalScience·DateAug 23, 2007

Surgery for severe obesity saves lives

A long-term study published in The New England Journal of Medicine reveals that bariatric surgery reduces mortality in severely obese patients by 29%. The researchers found that the actual weight loss is less important than the surgery itself in reducing risk, opening up new possibilities for treatment development.

SourceSwedish Research Council·JournalNew England Journal of Medicine·DateAug 23, 2007

Are civil unions a 600-year-old tradition?

A new study suggests that homosexual civil unions may have existed in France six centuries ago, challenging common assumptions about the history of same-sex relationships. The affrèrement, a medieval legal contract, provided a framework for non-nuclear households and shared characteristics with marriage contracts.

SourceUniversity of Chicago Press Journals·JournalThe Journal of Modern History·DateAug 23, 2007

Mouse vision has a rhythm all its own

Researchers found that mice lacking a critical component of the retinal clock exhibit abnormal gene activity and defective electrical responses, but their eyes appear normal. The study suggests that the retina's autonomous circadian clock plays a crucial role in visual processing.

SourceCell Press·JournalCell·DateAug 23, 2007

Inhaling helps heal liver transplant recipients

A new study suggests that inhaling nitric oxide during liver transplantation can decrease hospital stay time and improve liver function. The authors found increased levels of nitrite in circulation, which may mediate the beneficial effects of NO inhalation.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 23, 2007

Money illusion and the market

Money illusion refers to the phenomenon where people base their decisions on nominal values rather than real value, leading to irrational behavior in markets. Experimental evidence shows that firms are reluctant to cut prices during deflation due to money illusion, but more willing to increase prices during inflation.

SourceUniversity of Copenhagen·JournalScience·DateAug 23, 2007

JCI table of contents: Aug. 23, 2007

Researchers found that FTY720 prevents disease in mouse models of leukemia caused by the cancer protein BCR-ABL. Nitric oxide inhalation also accelerates restoration of liver function after transplantation, reducing hospital stay times.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 23, 2007

UC's Fry informs fantasy football fans

Assistant Professor Michael Fry and student Andrew Lundberg developed a model to help fantasy football players make informed decisions during drafts. The team's approach uses a combination of player value, available players, and team need to identify the best players to select.

SourceUniversity of Cincinnati·JournalJournal of Quantitative Analysis in Sports·DateAug 23, 2007

New weapon to fight leukemia

Researchers at Ohio State University have identified a new potential treatment for leukemia, FTY720, which prevents disease in mouse models of various leukemias. The drug activates tumor suppressor PP2A, reactivating it in cancer cells.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 23, 2007

American College of Medical Genetics responds to new FDA labeling decision for warfarin

The American College of Medical Genetics recommends using genetic testing to guide warfarin dosing and reduce the risk of bleeding complications. The review suggests that genetic variants in CYP2C9 or VKORC1 can be used to determine optimal dosing levels, but further research is needed to address clinical utility and balance between ha...

SourceAmerican College of Medical Genetics and Genomics·JournalGenetics in Medicine·DateAug 23, 2007

OSU joins ocean observatories initiative

Oregon State University will lead a component of the National Science Foundation's Ocean Observatories Initiative, located in the Pacific Northwest's coastal ocean. The $331.5 million research facility project will create a distributed, multi-tiered observatory spanning global, regional and coastal scales.