Researchers identified prokineticin 2 as an appetite suppressant that works in rodents and may be used to develop an effective weight loss therapy. The molecule reduced hunger and led to significant weight loss of almost 5 percent in lean and obese mice.
A new animal study has identified a specific genetic cause of fetal alcohol-related developmental disorders, which may lead to targeted treatment. Fetal alcohol exposure can disrupt thyroid hormone levels, leading to neurodevelopmental disorders such as emotional behavioral disorders and deficits in learning, memory, and speech.
A new study found that longer breastfeeding duration and higher-quality weaning diets can shape a child's body composition. Children who were breastfed for longer periods had lower fat mass, while those with higher quality weaning diets had greater lean mass at four years of age.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that injecting testosterone undecanoate monthly can effectively prevent pregnancy. After thirty months, the cumulative contraceptive failure rate was 1.1 per 100 men.
A new study found that babies born with lower weight are more likely to develop chronic diseases like heart disease and diabetes later in life due to increased inflammation. Researchers followed over 5,600 children from birth to adulthood, finding a link between early growth and adult inflammation.
A new study suggests that balancing two types of estrogen and a hormone in the placenta can signal labor. Researchers found that when estradiol (E2) and estriol (E3) are in balance, there is no drive to labor, but an imbalance leads to the onset of labor.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that obese women have detrimental changes in their ovaries, leading to poorer reproductive outcomes. Alterations in egg development and increased inflammation may contribute to infertility, the researchers suggest.
A new study finds that obesity is biologically associated with an unsatisfying sex life, which can be reversed through weight loss via gastric bypass surgery. Researchers measured reproductive hormone levels and quality of life ratings in obese men before and after surgery.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that growth hormone treatment after weight loss surgery reduces lean body mass and skeletal muscle mass losses. Researchers discovered that short-term growth hormone treatment during a standardized diet and exercise program increased l...
A new study found a positive relationship between vitamin D levels and muscle power, force, velocity, and jump height in adolescent girls. The researchers measured serum vitamin D levels in 99 adolescent girls and used jumping mechanography to assess muscle power.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that cigarette smoking during pregnancy is associated with changes in maternal thyroid hormone levels. Smoking-related changes in thyroid function extend to the fetus, potentially leading to impaired neuropsychological development.
A new study found that increasing alkali content in the diet through fruits and vegetables can counteract acid-induced bone loss. The study discovered bicarbonate has a favorable effect on bone resorption and calcium excretion.
A new study finds that pediatric obesity can alter thyroid function and structure, with a potential link between fat excess and thyroid tissue modification. Thyroid function returns to normal after weight loss, but the persistence of abnormalities in obese children may progress into chronic disease in early adulthood.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that dose-dependent growth hormone treatment increased final height in children with short stature who are not GH deficient. Children from parents of normal height responded better to treatment than those from short parents.
Researchers found significant declines in hip bone mineral density after gastric bypass surgery, associated with the extent of weight loss. Calcium and vitamin D deficiencies may be due to alterations in the gastrointestinal tract during these procedures.
A study by the Endocrine Society suggests prenatal testosterone excess may contribute to low sperm counts and reduced fertility in males. Researchers found that exposure to high levels of testosterone during fetal development can negatively impact male reproductive health.
The Endocrine Society has released a new clinical practice guideline for the detection, diagnosis, and treatment of primary aldosteronism. The guidelines recommend using the aldosterone-to-renin ratio to diagnose PA in higher-risk patients.
A new study published in the Journal of Clinical Endocrinology & Metabolism found that HIV-infected patients have a higher prevalence of fractures compared to non-HIV infected patients. The study analyzed data from over 8,500 HIV-infected patients and more than 2 million non-HIV infected patients, revealing a significant increase in fr...
A new study found that those who drink excessively are at increased risk for metabolic syndrome, a condition associated with cardiovascular disease. The study analyzed data from over 1,500 participants and found that most people in the US drink in ways that may increase their risk of metabolic syndrome.
A new study found that a protein produced by fat cells may increase the risk of heart attack in older adults. Adiponectin levels were associated with a higher risk of heart disease events, particularly among those with high levels.
A new study by The Endocrine Society found that male recreational athletes who believed they were using growth hormone experienced improved athletic performance, even when given a placebo. In contrast, female athletes showed little benefit from the placebo effect.
A recent study published by the Endocrine Society found that exercise does not suppress appetite in obese women, unlike lean women. Obese women showed no significant reduction in leptin levels during intense exercise, which is essential for appetite suppression and weight loss.
A new study from Germany suggests that men with low testosterone levels are at a higher risk of dying from all causes over time. The study found that men with low testosterone had more than 2.5 times greater risk of dying in the next 10 years compared to those with normal testosterone levels, regardless of age or lifestyle factors.
A new study suggests that a diet with a big breakfast of carbs and protein can lead to more successful weight loss, as seen in the 8-month study where participants lost an average of 16.5 pounds. The high-carb and protein intake controlled appetite and cravings for sweets and starches.
Researchers have identified potential biomarkers for growth hormone that could aid in detecting doping in athletes. Several proteins increased or decreased in the blood of mice treated with growth hormone, offering new possibilities for testing.
A new study suggests that weight loss after gastric bypass surgery may improve immune function, protecting against cancer and infections. The study found that surgically induced weight loss increased the activity of natural killer cells, which play a critical role in controlling infections and cancer.
A new study found that laparoscopic gastric banding surgery improves the health of morbidly obese teenagers just six months after the procedure. The patients experienced significant improvement in measures of medical disorders, including abdominal fat, triglycerides, and blood sugar levels.
Restoring normal testosterone levels in hypogonadal men leads to major improvements in metabolic syndrome features. Older men (63+) benefit equally as younger men from testosterone treatment, according to studies presented at The Endocrine Society's 90th Annual Meeting.
A new study from Australia found that obese individuals feel a culture of blame and are often disrespected by medical practitioners. The study suggests that health care providers should do a more thorough assessment of the needs of individual obese patients, addressing social and psychological issues.
A study published by The Endocrine Society found that a mother's prenatal diet high in fat can lead to an early onset of puberty in her child, increasing the risk of adulthood obesity. The research also showed alterations in sex hormones and higher body fat levels in adult offspring.
A study found that metformin treatment delayed menstruation and decreased insulin resistance in young girls at risk of early puberty. The treatment also reduced abdominal fat and improved cholesterol levels, lowering the risk of future heart disease.
Researchers have identified a new family of compounds that can effectively treat estrogen receptor-positive breast cancers resistant to tamoxifen. The compounds, including TPBM and related agents, work by inhibiting the growth of cancer cells stimulated by estrogen.
A new gene therapy has helped pet dogs with cancer live longer by increasing muscle strength and correcting common complications. The treatment has been shown to improve quality of life and survival rates, with 54% of dogs responding to the therapy and surviving 84% longer.
A new study found that three months of aerobic exercise decreased body fat and calorie intake in overweight and obese people, with increased levels of brain-derived neurotrophic factor (BDNF) linked to reduced hunger and weight loss.
Researchers found that resveratrol inhibits the growth of pre-fat cells and prevents them from converting into mature fat cells. Resveratrol also reduces production of cytokines linked to obesity-related disorders, such as diabetes and clogged coronary arteries.
Researchers found adult stem cells can improve fracture healing by increasing bone and cartilage formation at the fracture site. This approach may lead to a new treatment for people suffering from non-healing fractures, which can cause pain, deformities, and even death.
Researchers found that overweight individuals who used calorie-free tastants to flavor their food lost an average of 30.5 pounds over six months, compared to just 2 pounds for those who didn't use the tastants. This suggests that enhancing one's sense of taste can lead to weight loss by reducing hunger.
Researchers from Harvard University found that teenage athletes with hormone disorders may experience amenorrhea, leading to infertility and early bone density loss. Ghrelin levels were higher in amenorrheic girls than non-athletes, suggesting a link between energy deficit and menstrual irregularities.
A new study by The Endocrine Society reveals that low testosterone may cause health problems leading to erectile dysfunction, metabolic syndrome, and cardiovascular disease. Researchers found that 18.3% of men with erectile dysfunction had undetected testosterone deficiency.
A new study by The Endocrine Society found that overweight men are not more likely to be infertile, contradicting previous research on obese women. Greater body weight was linked to lower testosterone levels in some participants, but impaired sperm production remains the primary cause of infertility in men.
A new multicenter study is being conducted to assess the safety of testosterone gel (LibiGel) for postmenopausal women with low sexual desire. The study aims to enroll 2,400 to 3,100 women aged 50-80 with hypoactive sexual desire disorder and follow them for at least a year.
Women with type 2 diabetes and heart disease have poorer control of both diseases and receive less intensive medical treatment than do men. Women are also more likely to have uncontrolled high blood pressure and poor long-term control of their blood glucose levels compared to men.
A new study by The Endocrine Society found that moderate fitness levels lower the risk of death in diabetic men, reducing mortality by 40-50% over seven years. Fitness levels were categorized as low, moderate, and high based on peak metabolic rate achieved during exercise.
A new study finds that pregnant women with high insulin resistance are at a higher risk of pregnancy complications, including preeclampsia, premature rupture of membranes, and cesarean sections. Babies born to these women also face increased risks of macrosomia and hypoglycemia.
A new Canadian study found that the standard screening test for high blood sugar in children with risk factors misses nearly 3 times fewer cases of prediabetes than a longer test. The glucose stress test identified more cases of both prediabetes and metabolic syndrome. Early detection is crucial, as it can prevent or delay diabetes.
A new animal study suggests that estrogen treatment is not toxic per se, but its effects on the brain depend on an individual's reproductive age. In rats, estrogen therapy reduced brain damage when given before menopause, but increased it after, highlighting a narrow window of time for neuroprotective benefits.
A new study found that some patients with type 2 diabetes can maintain good blood sugar control for years using non-insulin oral diabetic medications. The study of 191 veterans showed that 55% of patients remained on oral drugs and achieved improved hemoglobin A1c levels.
Experts recommend revising current criteria for diagnosing diabetes, suggesting the use of hemoglobin A1c (HbA1c) as an alternative to fasting plasma glucose or oral glucose tolerance tests. This change may help identify more people with undiagnosed diabetes, reducing avoidable morbidity and mortality.
Researchers found that children can safely take ten-times the current recommended daily allowance of vitamin D, which may have long-term health benefits. Vitamin D is essential for bone growth and development in children, and supplementation with high doses (2,000 IUs) has been well-tolerated and safe.
A new study found that elderly men with higher IGF-1 bioactivity have a significantly lower mortality rate compared to those with low bioactivity. The researchers used a new method to measure IGF-1 function, which revealed the association between high circulating IGF-1 bioactivity and extended survival.