A new study on fruit flies found that reducing insulin/insulin-like growth factor (IIS) signalling pathway in fat tissue extends life by up to 50%. The system, which governs longevity, is likely to be conserved in humans. Increasing dFOXO levels in fat cells also extended lifespan and reduced fertility.
The CARDS trial found that a daily 10mg dose of atorvastatin reduced the risk of serious heart problems by 36% and strokes by 48%. The benefits were observed even in patients with already low LDL-cholesterol levels. This study has significant implications for the cardiovascular health of people with Type 2 diabetes.
Researchers at UCL's Institute of Neurology found that memories are distributed across different brain regions, not just one area. This means that a single sense can reactivate a memory, rather than requiring all aspects to be recreated.
Researchers discover novel gene BBS5, necessary for generating cilia and flagella, which are involved in the development of Bardet-Biedl syndrome. The study confirms that BBS is caused by defects in cilia, a theory first proposed by Dr Philip Beales.
Researchers at University College London developed more effective crime hotspot maps by treating the spread of crime like a disease, capturing 62-80% of burglaries and being 30% more accurate than traditional methods
Scientists have successfully measured the activity of a single granule cell in an intact brain using patch-clamping technique, confirming predictions made over 30 years ago by David Marr. This breakthrough could lead to better understanding and treatment of movement disorders like ataxia and dysmetria.
Researchers have identified a novel gene linked to familial Parkinson's disease, revealing a new pathway for therapeutic treatment. The discovery places mitochondrial function at the centre of Parkinson's research, particularly in relation to oxidative stress and brain cell degeneration.
A study by researchers at University College London found that when participants were lifting a heavy box, they perceived the weight of an actor's lifted box as lighter than it actually was. This suggests that our brains use simulation theory to understand others' actions, which can lead to biased judgments in social situations. Accord...
Researchers question current disease treatment theory, suggesting new treatments targeting neutrophil leukocytes instead. The study's findings could lead to a re-evaluation of antioxidant therapies and a shift in medical practice.
A UCL study found that empathy for pain involves the affective but not sensory components of pain, and is triggered by the perception of a loved one's pain. The researchers discovered specific brain regions are activated when observing another person in pain, highlighting the emotional representation of internal bodily states.
A UCL study found that both maternal and romantic love activate specific brain regions involved in the reward system, while reducing activity in systems for negative judgments. The research also showed similar mechanisms of love in animals and humans, linking them to oxytocin and vasopressin.
A clinical trial of Prana's Alzheimer's disease drug, PBT-1 (Clioquinol), has shown a significant reduction in AD development. The study found an average change in score at 24 weeks of about 1.5 points on PBT-1 and about 8.9 on placebo.
Researchers at UCL's Wolfson Institute for Biomedical Research have developed a new drug to treat enlarged prostate with virtually no hormonal side effects. The treatment can both relax the prostate and prevent its growth, offering a major advance in treating a condition affecting millions of men worldwide.
A new study reveals a significant increase in Arctic summer melt season length, threatening polar bears' survival and global climate stability. The research uses radar data from European and American satellites to measure changes in Arctic sea ice thickness, shedding light on the impact of global warming.
A new study suggests that children's brains are wired to downplay the sensation of their own physical actions, leading to increased force being used in play. This mechanism may also explain why kids can't tickle themselves, but feel the full effect when someone else does.
Researchers at UCL create first laboratory-generated deep and intermediate focus earthquakes, recreating extreme pressure and temperature conditions. The study reveals dehydration reactions as the cause of these enigmatic earthquakes, which can occur hundreds of kilometers below the Earth's surface.
Researchers at University College London have discovered a potential new cancer treatment using compounds found in cola beverages, coffee, tea, and chocolate. The compounds block the operation of a key enzyme linked to cell growth and blood clotting.
A new drug, CPHPC, has been developed to remove a blood protein linked to amyloidosis, a disorder that claims 1,000 UK lives annually. The drug blocks SAP proteins from sticking to amyloid fibers, speeding up their removal and offering potential treatment for Alzheimer's and diabetes.
A new model predicts a mega-tsunami could devastate the US coastline, with wave heights reaching 100 meters on the West Saharan shore and 50 kilometers high in Florida. The energy released would be equivalent to the electricity consumption of the entire United States in half a year.
Researchers found that a specific Apo-E gene variant increases the risk of coronary heart disease (CHD) in current smokers, with men carrying the E4 version facing a three times higher risk. The study suggests that quitting smoking can reduce this risk and highlights the importance of reducing smoking to avoid CHD.
Researchers at University College London have developed a novel approach to determine the melting temperature of iron at high pressures, allowing them to estimate the Earth's core temperature. This breakthrough has significant implications for understanding earthquakes, volcanoes, and the Earth's magnetic field.