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Science News for August 9, 2004


Biologists deciphering complex lemur scent language

Researchers at Duke University have been studying ring-tailed lemurs' scent language to understand their complex chemical communications. The scientists found that lemurs use 'scentences', combinations of scents extending their chemical messages, and identified specific compounds in their scent profiles.

You are what you eat: New insight into autophagy

Autophagy, a natural process where cells recycle damaged organelles, is induced by starvation or inhibition of key signaling pathways. Researchers discovered that an insect hormone ecdysone promotes programmed autophagy via PI3K signaling regulation, highlighting the complexity of autophagy control in multicellular animals.

SourceCell Press·JournalDevelopmental Cell·DateAug 9, 2004

Small animal imaging gives cancer clues

UC Davis researchers have created a PET scanner that can image tiny cancer growths in mice, allowing them to monitor tumor development over time. The system enables early detection of cancer transformation and could lead to more sensitive screening tests for cancer-fighting drugs.

SourceUniversity of California - Davis·JournalProceedings of the National Academy of Sciences·DateAug 9, 2004

Short-term hormone therapy: Risks and benefits

Researchers found that short-term hormone therapy can be beneficial for women with mild to severe menopausal symptoms, but may not be suitable for those at high risk of cardiovascular disease. The study suggests that the decision to use hormone therapy should be based on individual goals and CVD risk.

SourceJAMA Network·JournalArchives of Internal Medicine·DateAug 9, 2004

Study examines inappropriate medication prescribing for elderly patients

A study published in Archives of Internal Medicine found that 21% of elderly patients fill prescriptions for potentially inappropriate medications, with Amitriptyline and doxepin being common culprits. The researchers used a large national pharmaceutical benefit company's outpatient claims database to identify these inappropriate medic...

SourceJAMA Network·JournalArchives of Internal Medicine·DateAug 9, 2004

Evolvability could be a driving force in drug resistance

A computer simulation by Rice University scientists suggests that the ability to evolve can itself be favored through natural selection. This idea challenges traditional views and provides insights into the evolution of drug resistance in bacteria, immune system cells, and higher-order organisms.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateAug 9, 2004

Sex pheromone blocked in bug

A team of scientists has identified an enzyme called CYP4AW1 that breaks down insect pheromones, allowing for the development of targeted treatments to prevent agricultural pests from breeding. By blocking this enzyme with a specific chemical, researchers may be able to disrupt the communication between insects and prevent infestations.

SourceUniversity of California - Davis·JournalProceedings of the National Academy of Sciences·DateAug 9, 2004

Promising hospital anti-infection strategy probably won't work, study shows

A new model shows that antibiotic cycling, alternating between classes of antibiotics every few months, probably won't work in stopping the spread of hospital-acquired antibiotic resistance. Instead, a mixing approach, where patients receive different antibiotics randomly, may be more effective in reducing resistance levels.

SourceUniversity of Washington·JournalProceedings of the National Academy of Sciences·DateAug 9, 2004

Size does matter when choosing a mate

Scientists analyzed mating behavior and body size of over 100 shorebird species to explain Rensch's rule. Larger shorebirds show competitive battles on the ground, where bigger males have an advantage, while smaller species feature aerial battles where agility is key.

SourceUniversity of Bath·JournalProceedings of the National Academy of Sciences·DateAug 9, 2004