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University of California - Irvine


Role of key protein that may stave off inherited form of Alzheimer's disease discovered by UC Irvine researchers

Researchers at UC Irvine have discovered a protein called calsenilin that can offset calcium imbalances in brain cells, which contribute to the development of early-onset familial Alzheimer's disease. This finding may lead to pharmaceutical therapies and preventive measures to halt the progression of this neurological disorder.

SourceUniversity of California - Irvine·JournalProceedings of the National Academy of Sciences·DateJul 31, 2000

UC Irvine molecular biologists discover key protein interaction that stabilizes cholesterol levels in cells

UC Irvine molecular biologists have discovered a key protein interaction that regulates cholesterol levels in cells, which may provide insights into heart disease and stroke prevention. The study found that a regulatory protein called Sp1 recruits a co-regulating protein to activate genes that balance cholesterol levels.

SourceUniversity of California - Irvine·JournalProceedings of the National Academy of Sciences·DateJun 6, 2000

UC Irvine researchers discover how airborne sea salt particles may influence air pollution levels

Researchers found that airborne sea salt particles undergo a chemical reaction in daylight to release chlorine molecules, which can influence ozone levels. This discovery suggests that sea salt particles may play a significant role in determining the levels of certain greenhouse gases and air pollutants in coastal urban areas.

UC Irvine researchers discover new technique for analyzing crucial cell activity in limb regeneration

Researchers at UC Irvine have developed a method to study the function of genes necessary for limb regeneration in salamanders, a finding that may provide key information for treating ailments like spinal cord injury and deep wounds. By understanding the process of regeneration, researchers may find new approaches and therapies for rep...

SourceUniversity of California - Irvine·JournalDevelopmental Biology·DateFeb 9, 2000