Scientists at the University of Toronto have made a breakthrough in understanding how to diagnose, treat, and potentially prevent infectious prion diseases like mad cow disease. By identifying specific amino acid sequences on abnormal prions, they were able to develop antibodies that can recognize and attack these rogue proteins.
Researchers at U of T have created a topographical map of the 'beating heart' of lasers, allowing for more accurate design and diagnosis. The study could influence laser design, improve diagnosis of faulty lasers, and potentially reduce manufacturing costs.
Professor Elizabeth Legge explores how British art marketed itself as a failure to gain cultural credibility in the US. She argues that this strategy tapped into American perceptions of British art as gauche and incapable of irony, generating mutual indignation between the two nations.
Researchers at the University of Toronto have discovered a gene, Fkbp6, essential for male fertility but not female fertility. The study shows that the gene plays a critical role in sperm cell development and chromosome pairing, highlighting potential new principles in how cells control the number of chromosomes.
The study identifies changes to rate-determining factors at transition points, shedding new light on the nature of non-linear spreading. Researchers used a model to calculate these changes and found them to be crucial for understanding various phenomena such as 'avalanches' in sand piles.
Researchers have developed an antibody-coated stent that reduces restenosis and prevents blood clots, leading to improved cardiovascular treatment outcomes. The device captures endothelial progenitor cells to promote healing and prevent re-narrowing of the artery.
A study found that mice genetically engineered to lack a molecule called Stem Cell Antigen-1 (Sca-1) experienced normal bone development but exhibited decreased bone mass and brittle bones as they aged. The researchers believe that defective maintenance of stem cells may contribute to age-related osteoporosis in humans.
A University of Toronto geologist claims that diamonds originated on the ocean floor, supported by a new study published in Nature. The research reveals that diamond formation begins when lava is pushed onto the ocean floor, interacting with sea water to alter its oxygen composition.
A University of Toronto study examines the 2000 Walkerton and 2001 North Battleford water contamination outbreaks, blaming systemic failures on human factors. The research highlights the importance of information circulation, competence, and public safety guidelines in complex systems.
Researchers at University of Toronto have developed a material that converts electrical current into photons, holding promise for directly linking computers with networks transmitting information in light. The study demonstrates the conversion of electrical current into light using a promising class of nanocrystals, paving the way for ...
Research suggests that undernutrition in pregnant women can lead to premature birth, with fetuses having accelerated adrenal gland maturation and premature delivery. Despite this, lambs born prematurely were not underweight or small for their gestational age.
Researchers found people affected by seasonal depression are more risk-averse when days are shorter in the fall but more willing to take risks as daylight lengthens in winter. This seasonal stock market fluctuation has a negative effect on autumn markets and a positive one during winter.
A study by Catherine Ortner found that intoxicated individuals may actually make more cautious decisions than sober counterparts in certain situations. The research suggests a complex relationship between alcohol consumption and decision-making processes.
A University of Toronto study estimates that pain pump programming errors could result in up to 667 deaths, with reporting rates ranging from 1.2% to 7.7%. The researchers recommend redesigning the control panel using human factors engineering techniques to reduce human error.
The study generates a comprehensive description of human chromosome 7, including medically relevant landmarks and disease-related mutations. The database is publicly accessible, enabling healthcare professionals and researchers to identify specific genes associated with diseases such as autism.
The Structural Genomics Consortium will determine the three-dimensional structure of over 350 human proteins, focusing on cancer, neurological disorders, and infectious diseases. The project aims to produce protein structures by the end of 2003, with all structures released freely into the public domain.
Researchers have discovered that caspase-8 is essential for the activation of T-cells at the start of the immune response. The study found that inhibiting caspase-8 significantly decreases the immune response.
A study by University of Toronto researchers found that walk-in patients with minor illnesses have a minimal impact on emergency department overcrowding. The study's authors suggest increasing hospital capacity to quickly assess and admit acutely ill patients is key to solving the issue.
A new study reveals that iron deficiency leads to significant economic losses, particularly in developing countries. The research estimates that iron deficiencies result in a 0.6% loss of GDP due to physical productivity losses from adults lacking iron, rising to 4% with added learning and motor impairments.
Researchers at the University of Toronto have discovered a new physics phenomenon that uses metamaterials to create a focused beam of light. By amplifying evanescent waves and correcting their phase, these lenses could revolutionize the engineering of electronic devices at the nanometre scale.
A scholar suggests that an economic system may be a contributing factor to dissatisfaction in the West. Her book, Radical Gratitude, proposes that people can be happier by being more grateful for what they possess and have accomplished.
A five-year, $10 million project recruits families with multiple anorexia members to analyze DNA and identify genes contributing to the disease. The study aims to improve detection, prevention, and treatment of anorexia nervosa, a serious illness with high mortality rates.
According to University of Toronto researchers, the brain uses prior knowledge to guide perceptions and ignores or downplays small changes. The brain gauges probabilities and makes the best possible use of flawed sensor data to form a coherent picture.
A team of researchers has identified a genetic mutation in phospholamban that disrupts calcium regulation in the heart, leading to dilated cardiomyopathy and heart failure. The discovery provides new insights into the mechanisms underlying heart failure and holds promise for future treatments.
A new study aims to investigate the effects of intensively controlling blood sugar, blood pressure, and lipid levels on cardiovascular disease risk in adults with type 2 diabetes. The ACCORD study will test three medical treatment strategies to determine their impact on CVD risk.
A major study found that patients who survive acute respiratory distress syndrome (ARDS) show significant improvement in exercise capacity and quality of life over time. Despite persistent muscle wasting and weakness, survivors achieve 66% of healthy patient exercise capacity at one year and return to work in most cases.
A study by Professor Shelley Peterson found that teenagers' writing is closely linked to gender stereotypes, with students tending to write socially acceptable themes. The research revealed that students were reluctant to explore non-traditional topics, instead favoring traditional gender roles and styles.
A new laser-based technique can detect developing cavities in teeth, revealing defects at very early stages of development. This photo-thermal method avoids the need for heavy lead aprons to protect patients from hazardous X-rays, making it a promising tool for preventive treatment.
Comparative literature expert Eric Cazdyn examines the relationship between Japanese film history and societal shifts. His research reveals how changes in film techniques reflect broader cultural transformations, including increased citizen participation and experimentation during times of economic turmoil.
A study published in the Journal of Medical Systems found that internet use empowers patients and improves the physician-patient relationship. Patients who access health information online can arrive with background knowledge and ask informed questions, saving time for doctors.
Researchers found convincing evidence of sexual dimorphism in fossils from 252-260 million years ago, with male Diictodon having large tusks used as weapons for combat. The study suggests complex social behavior among ancient animals.
A study led by Dr. Donald Redelmeier found a 41% increase in driving fatalities after the Super Bowl, with a peak during the first hour after the game ends. The researchers suggest avoiding unnecessary night driving and consider trauma centers adding more night staffing to combat this risk.
A recent study by University of Toronto researchers found that walk-in clinic physicians spend similar amounts of time with patients as traditional family practitioners. The study also revealed high levels of personal satisfaction among walk-in clinic doctors regarding key aspects of their work.
A recent study by University of Toronto researchers found that investment banks prioritize past cooperative relationships and industry reputation when selecting underwriting partners. This challenges the conventional wisdom that talent and high returns are key factors in business dealings.
Sick Kids researchers discovered that nervous system autoimmunity attacks insulin-producing cells in the earliest stages of Type 1 diabetes. By modifying the attack on nervous tissue, they prevented subsequent diabetes in animal models, suggesting a critical role for early neuronal autoimmunity.
A researcher at the University of Toronto has developed a method to automatically remove the unsightly scarlet spots, known as red-eye, from digital images. The software isolates the reddened areas of the eyes and replaces them with natural eye color, providing a convenient solution for consumers.
A University of Toronto researcher is studying how the Cherokee people responded to forced removal, with a focus on accommodationist writers and resistant voices. His book aims to acknowledge the history of removal and its impact on Cherokee literature.
Scientists have identified the gene responsible for Shwachman-Diamond syndrome, a rare genetic disorder that affects the pancreas, white blood cells, skeletal system, and causes severe infections. The discovery will aid in accurate diagnosis, clinical management, and potentially lead to new therapies.
Researchers at University of Toronto and Princess Margaret Hospital have discovered the key mechanism behind IP3 molecule's role in setting calcium levels within cells. This finding holds promise for developing novel treatments against epilepsy by regulating calcium waves.
Researcher Andrea Most examines the works of influential Jewish American composers, revealing how Broadway musicals addressed complex issues of identity, assimilation, and American culture. Her book will shed new light on the genre's often-overlooked 'Jewish origins' and its impact on the American experience.
A sociologist's study of over 20,000 adults from 178 countries reveals that people are maintaining existing social connections while adding internet communication. The findings also show that the internet is a preferred method for communicating with distant friends and relatives, but can be both beneficial and burdensome.
Breast reconstruction rates in Canada are low due to a lack of knowledge among physicians, with only 7.9% undergoing the procedure. Plastic surgeons and primary care physicians alike have expressed lower levels of knowledge on the subject.
Researchers at the University of Toronto have developed a novel nanoscale electronics circuit that can detect the presence of a single electron. This breakthrough could enable the creation of ultra-sensitive biosensors capable of detecting important biological molecules, including DNA.
A study found that individuals with lower incomes and education levels are more likely to have severe arthritis but less likely to be on waiting lists for joint replacement surgery. Women from lower socio-economic backgrounds are also less likely to discuss joint replacement with their doctors.
Researchers studied the health and economic implications of screening and treating new immigrants from developing nations for latent tuberculosis infection. They found that implementing this practice could avoid up to nine thousand future active tuberculosis cases and save $60 to $90 million per year in healthcare costs.
Researchers found that a mixture of oxygen and carbon dioxide improves oxygen delivery to the brain, decreasing risk of permanent brain damage. The new treatment may reduce symptoms and improve outcomes for severely poisoned patients.
A study published in Metabolism found that a vegetarian diet combining soy proteins, nuts, viscous fibers, and plant sterols reduces LDL cholesterol levels by 29%. The combination diet was as effective as the first generation of statin drugs in lowering blood cholesterol.
A new study of snow accumulation on Mount Logan provides evidence that significant climate change has occurred in Western Canada, with both surface and atmospheric temperatures rising since the mid-19th century. The research warns of warmer winters and changes in weather patterns if current trends continue.
A unique insect study reveals that male antler flies deteriorate with age, showing a decrease in survival and mating success as they get older. The study provides valuable insights into the aging process in insects living in their naturally evolved environment.
A study found that an uncommon variation of the Nogo gene increases schizophrenia risk, particularly when inherited from both parents. One in five people with schizophrenia has this risk gene, and researchers hope to discover new related genes to aid diagnosis and treatment.