Researchers found a rare Y chromosome type, known as hgA1, in one third of men with a specific Yorkshire surname, suggesting a centuries-old connection to Africa. The study sheds light on the complex history of human migration and challenges traditional notions of racial identity.
Scientists at Oxford University have identified a surprising way to switch off a gene involved in cell division using a previously unknown type of RNA. This discovery could lead to new anti-cancer treatments by inhibiting the production of an enzyme that controls thymine production.
Patients with hippocampal damage experience severe impairments in imagining new experiences and planning for the future. They struggle to visualize complex scenarios, instead seeing fragmented images. Researchers suggest a common brain mechanism underlying memory recall and imaginative thinking may be affected.
Researchers are developing novel antibacterial compounds targeting MRSA, a life-threatening drug-resistant infection. The new medicines block the ability of MRSA bacteria to divide and multiply, reducing resistance levels.
Scientists at ProXara Biotechnology Limited have identified a way to prevent tumour cells from growing by switching off key enzyme PKB. The research, funded by the Wellcome Trust Seeding Drug Discovery initiative, aims to develop a drug that can be used in clinical trials for lung cancer treatment.
Researchers have identified pancreatic polypeptide as a potential solution to appetite suppression, which may lead to a new obesity treatment. The hormone is naturally released in the gut and acts as a neurotransmitter to indicate fullness to the brain.
A study published in Nature Medicine found that targeting specific HIV proteins can lead to effective control of the virus. Researchers suggest that a more targeted vaccine approach may be necessary.
The study reveals that Salmonella enterica serovar typhi is the most common cause of bacteraemia in children and adults, with almost half of all cases found in children. Local knowledge is crucial for developing effective public health interventions, particularly in a resource-constrained healthcare system.
Researchers at UCL and Imperial College London found that positive sounds like laughter trigger a brain response similar to smiling. This response occurs in the premotor cortical region, preparing facial muscles for laughter, and may play a role in building strong bonds between individuals.
Researchers are creating a global map of malaria risk to identify populations most at risk and predict disease impact. The Malaria Atlas Project will use satellite data, population censuses, and electronic information to create a detailed map of malaria transmission in Africa.
The £4 million grant will enable CIMR to stay at the leading edge of disease research and train tomorrow's academic doctors and medical scientists. The Institute aims to understand human illnesses at a molecular and cellular level, facilitating collaboration between clinicians and basic scientists.
The hippocampus predicts future events by recalling associated memories and comparing past experiences to present ones. Damage to the hippocampus affects sequence memory and navigation abilities.
Researchers found a process called 'trans-conditioning' influences whether a T cell becomes an effector or regulatory cell. This discovery may lead to new treatments for diseases such as cancer and autoimmune disorders like type I diabetes and arthritis.
A new study provides a reliable way to diagnose cerebral malaria in children through changes to the retina. This discovery could greatly reduce child mortality rates from this major childhood killer.
Research shows that people who feel in control of their lives are less effective at coping with pain when it's beyond their control. Teaching psychological coping strategies helps reduce pain effects. The study suggests acceptance-based therapy may be a more effective approach to managing persistent pain.
The Wellcome Trust Centre for Neuroimaging at UCL will further bolster the reputation of a laboratory renowned for its research into neural cognition and common neurological diseases. The centre aims to study the functional architecture of the human brain to identify core mechanisms causing common human neurological diseases.