Articles tagged with Medical Tests
The Joslin Diabetes Center is participating in two NIH-funded clinical trials to test artificial pancreas systems that automatically monitor and regulate blood glucose levels. If successful, the trials could lead to regulatory approval for use of these devices, improving glucose control and reducing diabetes self-management burden.
Researchers found that high cortisol levels in hair samples tracked closely with standard diagnostic techniques for Cushing Syndrome. The study's findings suggest that hair analysis may prove useful as a less-invasive screening test or confirmatory tool for the condition.
The study aims to understand the long-term neurologic effects of mild TBI and other deployment-related conditions. It will analyze the impact of TBI on thinking ability, memory, mood, and focus, as well as explore biological factors that influence outcomes.
Researchers have identified Mycobacterium chimaera bacteria transmission from contaminated cardiac surgery machines in Australia and New Zealand. The infection can cause serious illness but may be treated with antibiotics, according to a new test developed by the University of Melbourne team.
Researchers found significant differences among dialysis testing methods, which can lead to inaccurate information and expensive nutritional interventions. They recommend revising federal guidelines to address the inconsistencies and improve care for patients with end-stage kidney disease.
A new study suggests a simple blood test can differentiate between Parkinson's disease and atypical parkinsonism disorders as accurately as a spinal fluid test. Researchers found that concentrations of neurofilament light chain protein in the blood can discriminate between these diseases.
Researchers at CWRU are testing a portable blood-adhesion monitor for sickle cell disease patients. The device aims to predict vaso-occlusive crises and help patients better manage their condition, potentially reducing physical and financial costs.
A mathematical model of bovine tuberculosis transmission from cattle to cattle and cattle to humans was used to analyze the cost and effectiveness of interventions in Morocco. The results showed that using a more conservative cutoff for a positive skin test could lead to cheaper and quicker elimination of the disease.
Researchers at Virginia Tech have developed a groundbreaking, portable tuned mass damper that reduces structural vibrations by up to 75% in tests. The device is compact, affordable, and easy to integrate into building designs, making it an accessible solution for reducing unwanted movements.
A new study has developed a mirror game test using computer avatars to accurately detect specific variations in patient movement and social interaction, showing comparable results to clinical interviews and neuroimaging methods. The test may provide an affordable and effective device for early diagnosis and management of schizophrenia.
A study found that current reprocessing techniques for flexible endoscopes are not consistently effective, with organic residues often remaining. Visual inspections and cleaning verification tests are necessary to ensure all endoscopes are free of damage and debris before reuse.
A study found that patients with renal dysfunction upon admission are more likely to die while hospitalized and have lower chances of being discharged home. Those with normal kidney function have better short-term outcomes, according to the estimated glomerular filtration rate (eGFR) test.
Researchers synthesized mono/di-halogenated coumarins and evaluated their anticancer activity against UACC-62, MCF-7, and PBM cell lines. The test compounds CMRN1-CMRN7 strongly suppressed cell proliferation and induced apoptosis in cancer cells.
Researchers at Duke University have developed a tiny device that uses sound waves to create whirlpools to gather proteins and other biomarkers from blood, urine or saliva samples. This innovative technology has the potential to form the basis of a small, inexpensive point-of-care device for early disease diagnosis.
A recent study published in the Journal of Oncology Practice found that oncologists often avoid discussing prognosis with their patients due to a cultural norm. By pausing to ask if patients want to talk about test results, oncologists can create an opportunity for more holistic discussions about life and death.
A NIH-sponsored clinical trial found that mindfulness meditation combats anxiety by reducing stress-hormone and inflammatory responses. Participants who took a mindfulness course showed big drops in these markers, whereas those in the control group experienced worsened responses.
A collaborative effort to improve CFD methodologies for evaluating medical devices has developed two benchmark models with robust experimental data. The study shows that 57% of simulation predictions were within one standard deviation of measured values, but more work is needed to develop widely-acceptable hemolysis solvers.
The ACA expanded insurance coverage and access to care for patients with chronic medical conditions, but nearly 1 in 7 remained uninsured. Home sleep testing was found to be as effective as lab testing in managing obstructive sleep apnea.
Researchers at Universidad Carlos III de Madrid develop innovative 3D bioprinting technology to produce living human skin, which can be used for transplantation and product testing. The breakthrough technology replicates natural skin structure and uses human cells, eliminating animal-derived collagen.
A study on chronic obstructive pulmonary disease (COPD) found that 44% of patients were under-treated, while only 19% received recommended medication regimens. Patients who were under-treated had fewer exacerbations, indicating that ignoring guidelines may be beneficial in certain cases.
Researchers found that approximately one-third of adults with a previous asthma diagnosis couldn't be re-diagnosed due to spontaneous remission or misdiagnosis. The study also highlighted the importance of objective testing to confirm asthma diagnosis, suggesting that failure to use these tests may lead to misdiagnosis.
Researchers found a correlation between parents' and babies' vitamin levels, with water-soluble vitamins higher in infants and fat-soluble vitamins in parents, particularly mothers. The study suggests tears could be used to replace clinical tests, potentially improving access to nutritional assessments for at-risk populations.
Researchers developed a mathematical model to determine the minimum number of people required for a good vaccine trial. Testing candidate vaccines on larger groups can accelerate the discovery of an effective vaccine against malaria, ultimately leading to its elimination.
A new urine test can quickly detect whether a person has a healthy diet by measuring biological markers created by the breakdown of foods. The test provides an instant indicator of whether a person is eating healthily, promising to revolutionize the way we assess diet quality.
A new study found that Medicaid expansion is associated with increased insurance coverage and improvements in asthma treatment, BMI screening, pap testing, and blood pressure control. Care quality also improved on seven measures, including care for asthma, pap testing, and hypertension, particularly among Hispanics.
An international expert workshop has outlined a strategy for reducing and replacing animal use in acute systemic toxicity testing. The report, published in Toxicology In Vitro, presents recommendations including gathering high-quality reference data and global harmonization.
Researchers designed a new diagnostic tool that measures gene activity in skin samples to predict disease progression of autoimmune diseases like systemic sclerosis. The test, called the SSc Skin Severity Score, can distinguish between patients who are improving and those who are not 12 months after treatment begins.
Researchers at OIST have created a novel sensor that detects biomolecules more accurately than ever before, using the additional function of measuring mass. This allows for more confident encapsulation of disease-detecting biomolecules within microfluidic platforms.
Researchers at UConn School of Medicine developed a new hearing test to identify binaural processing deficits in individuals with normal or near-normal audiograms. The study found that listeners with essentially normal clinical hearing test results may exhibit substantial deficits in binaural processing.
A reliable blood test can identify prion disease before symptoms appear, allowing for non-invasive diagnosis and potentially preventing transmission through blood transfusions. Researchers successfully detected abnormal proteins in the blood of presymptomatic donors with 100% accuracy.
Researchers discovered that sexually produced offspring were more than twice as resistant to infectious disease as their clonal sisters. The study used the waterflea, an organism that can reproduce both ways, and found that sex has large-scale benefits that make a difference to the next generation.
Preliminary research suggests that using a commercial brand of mouthwash can help kill off gonorrhea bacteria and control its spread. Daily rinsing with the product reduced viable gonorrhoea in the throat by 52% compared to saline solution.
The Association for Molecular Pathology (AMP) has published a joint guideline to standardize the interpretation and reporting of sequence variants in cancer. The guidelines aim to improve patient care by establishing standardized classification, annotation, interpretation, and reporting conventions for somatic sequence variants.
A team of UCLA researchers has developed an automated diagnostic test reader for antimicrobial resistance using a smartphone. The device connects to a phone and conducts testing on up to 96 wells, with results returned in under one minute.
A recent study published by the American Chemical Society found that red cabbage microgreens can help lower LDL, or 'bad', cholesterol and liver triglyceride levels in mice on high-fat diets. The microgreens contained more polyphenols and glucosinolates than mature red cabbage, making them a promising source of health benefits.
A new study by UC Riverside psychology professor Kate Sweeny found that optimists and pessimists alike brace for the worst when waiting for uncertain news, with no significant differences between the two groups. This challenges the common assumption that optimists are immune to anxiety and pessimism.
Researchers create method to detect C. parvum in source waters, improving public health protection. The calcium-mediated attachment of oocysts to environmental biofilms enables faster and cheaper detection.
A new study has developed an algorithm for accurate CJD diagnosis, achieving 100% sensitivity and specificity. The method uses cerebrospinal fluid samples or nasal swabs, showing promise for early detection.
The synthesized compounds showed potent anticonvulsant activity in the MES test, with Schiff bases of benzothiazol-2-ylamine being more effective than thiazolo[5,4-b] pyridin-2-ylamine. The log P values revealed a positive correlation with activity, with the most potent compound being benzothiazol-2-yl-(1H-indol-2-ylmethylene)-amine.
Researchers from Johns Hopkins Medicine have found that drone transportation of large bags of blood products can maintain their temperature and cellular integrity. The study suggests drones are an effective way to transport blood products to remote areas or time-sensitive destinations.
The American College of Physicians survey found that internists frequently prescribe high-cost treatments with little benefit to patients. Despite guidelines recommending against these practices, many physicians continue to use them, reflecting a desire to err on the side of treatment.
A new study found that the mannitol challenge test may not be accurate in detecting asthma in non-clinical settings. The test's predictive value was low in the general population, highlighting the need for caution when interpreting results.
Using a one-minute shared decision-making aid can reduce unnecessary hospitalization and advanced cardiac testing for patients with low-risk chest pain. The study found that the aid resulted in greater patient knowledge, increased patient involvement in decision-making, and reduced admissions for observation.
Researchers at Case Western Reserve University developed a portable sensor called ClotChip that can quickly and accurately assess blood's clotting ability. This technology has the potential to revolutionize the diagnosis and treatment of blood clots, allowing for faster and more precise assessments.
A study comparing four tests for PD-L1 expression has found that three tests cluster together, but the results vary with different scales. The goal of the ongoing study is to determine which test predicts treatment response most accurately.
A novel diagnostic biomarker panel can identify necrotizing enterocolitis in premature infants with high accuracy. The test, developed by LSU Health New Orleans researchers, has the potential to improve disease management and outcomes for thousands of preterm babies each year.
A case report highlights the risks of water intoxication in patients with urinary tract infections. Doctors recommend reevaluating hydration advice due to a lack of evidence, citing a high mortality rate for hyponatraemia.
A new urine test has been developed to detect biochemical changes associated with fatigue in workers, which could reduce errors and prevent accidents.
A team of Indian researchers created a model to describe the diffusion of liquids through paper, revealing new theoretical details. The study aims to control liquid spreading for precise creation of products involving paper-based technologies.
A study published in PLOS ONE reveals the potential clinical utility of an integrated, multi-modal battery of oculomotor, vestibular, and reaction time tests for detecting concussions. The results show promising sensitivities and specificities, paving the way for objective diagnostic tools at the point of injury or in emergency rooms.
Scientists have identified chemical changes in DNA that can be detected in blood samples, paving the way for a simple test to aid diagnosis. The findings could lead to a blood test to screen people who show symptoms of bowel diseases, sparing further tests for those without the signatures.
Adding higher frequencies to the American Academy of Pediatrics hearing test protocol helps detect adolescent hearing loss. Early detection enables modification of behavior to prevent continued damage. The study found that young adults with mild hearing loss may exhibit reading, emotional, or socialization problems.
A new study published in the Journal of Bone Joint Surgery has found that treatment with teriparatide accelerates bone healing and improves recovery after hip fractures. Patients who received teriparatide showed significant improvements in mobility and reduced pain compared to those treated with a different medication.
Researchers at TUM develop a new method for non-destructive testing using ultrasound that combines a computerized model and experiment to provide precise information on the inner world of objects. This method uses waveform inversion to utilize the entire information content of the wave field measured, providing improved results.
A simple saliva test for salivary urea nitrogen showed high accuracy in diagnosing kidney disease in adults in Malawi. The test also predicted patients' risk of early death, highlighting its potential to improve treatment outcomes.
Researchers found that estimating fitness can predict future risk of premature death from all causes, making it an easy and cost-effective tool for medical professionals. The study analyzed data from 38,480 men and women and found no need for complicated risk score algorithms.
The need for a bridging regulatory mechanism is highlighted in e-cigarette innovations; reducing the burden on regulators while maintaining product development. A reduced data set for initial products and focused tests for variants can support this process.
Case Western Reserve University researchers create sensor-enabled geometric blocks to assess cognitive skills, revealing hyperactivity and performance accuracy. The technology allows for customizable testing and training for individuals of any age, including those with developmental disabilities or brain trauma.
The Origami Diagnostics project aims to detect individuals carrying malaria parasites without symptoms, using a paper microfluidics-based test. The test is 100 times more sensitive and retains low cost and simplicity.
Researchers found that patients with pulmonary function testing had a lower risk of hospitalization and death from COPD. The study suggests that increasing testing for suspected cases could improve patient care and reduce healthcare costs.