Research on the tests that detect and monitor disease. Covers blood tests, cancer monitoring, emergency diagnostics, and new patent-pending assays.
A collaborative project is underway to develop non-animal test methods to replace the Rabbit Vaginal Irritation test for personal lubricants. Human in vitro tissue models may be used as a replacement, reducing animal testing and promoting more accurate assessments of product safety.
The Blink Reflexometer device detects changes in blinking patterns to identify concussions and neurological disorders like Parkinson's, Huntington's, and schizophrenia. The technology aims to provide a portable, rugged, and fast aid for trainers to make objective calls about player safety.
Researchers found that individuals with difficulty identifying odors had elevated AD-related proteins in their cerebrospinal fluid. The study suggests a potential cheaper alternative for tracking the progression of Alzheimer's disease through simple smell tests.
A new test has been developed to differentiate between Lyme disease and Southern Tick-Associated Rash Illness (STARI) with an accuracy of up to 98 percent. This breakthrough offers improved early detection and diagnosis for Lyme disease, a vector-borne illness affecting the US.
Experts call for more transparent conversations with women to avoid unnecessary disease labelling. A broader definition of polycystic ovary syndrome may lead to 'fear and anxiety', highlighting the need for a slower approach to diagnosis.
A new chewing gum-based diagnostic test can detect inflammation in the oral cavity within five minutes, allowing for early diagnosis and treatment. The test uses bittering agents to identify inflammatory conditions, which can help prevent serious complications such as bone loss.
After stem cell therapy, tests like SPEP/SIFE and SFLCA may yield oligoclonal patterns that resemble the original monoclonal antibody spike. However, this is a normal response to treatment, not recurrence of the disease. The key clarifier lies in tracking the location of the malignant spike before and after treatment.
The new TRI Analyzer can perform lab-grade medical diagnostic tests on patient blood, urine, or saliva samples as reliably as clinic-based instruments. The device, costing $550, analyzes samples using the power of a smartphone's camera and illuminates sample fluids with an internal LED flash or external laser diode.
Researchers found that stress levels and time since an adverse event can lead to the misidentification of harmless cues as threats, exacerbating anxiety disorders. The study provides new insights into how the human mind generalizes fear and could inform better treatments for PTSD.
A University of Bristol team has developed a new portable device to help doctors select the right antibiotic for a patient's infection. The rapid diagnostic test can determine which antibiotic is most effective within 20 minutes, reducing unnecessary use and potential complications.
A recently conducted study revealed that the cured-in-place pipe repair (CIPP) method can emit hazardous chemicals into the air, posing potential health hazards to workers and the public. The research found a complex mixture of organic vapor, water vapor, and liquid droplets of water, which can cause short- and long-term health impacts.
Researchers at Ohio State University have identified new physical biomarkers that can help confirm a diagnosis and predict disease progression. The study uses changes in proteins found in spinal fluid and blood to rate the severity of illness, identifying stages and progression with increased reliability.
A study found that wealthier, long-term residents in Ontario are more likely to get screened for colorectal cancer through colonoscopies rather than non-invasive tests. This gap is driven by the higher number of advantaged residents who prefer colonoscopies over fecal occult blood tests.
A study by EPFL scientists found that schizophrenia patients do not have a disturbed sense of body ownership. The study used the Full-Body Illusion test and showed that patients performed similarly to healthy controls, indicating that their sense of body ownership is unaffected by the disorder.
A new clinical decision support tool calculates and displays kidney failure risk based on criteria identified from a large cohort study. The tool automatically calculates and displays a risk score within the health record, making it easier for physicians to spot disease progression and take action.
A new hearing test, developed by researchers at the University of Southampton, has been implemented to assess auditory fitness-for-duty among military personnel. The test, a speech-in-noise test, takes into account real-world scenarios and challenges faced by soldiers, providing a more accurate measure of their hearing abilities.
Researchers found that regularly doing word puzzles like crosswords is linked to better brain function in later life. Participants who engaged with word puzzles performed better on tasks assessing attention, reasoning, and memory.
Researchers recommend early blood testing for iron deficiency in young women, especially those who have been menstruating for over three years. The study found that iron deficiency without anemia is common among adolescent females and can be associated with lower standardized math scores and attention problems.
A Danish study found that fermented red clover extract effectively prevents hot flushes, hormonal swings, and bone loss in women with menopause. The extract increases the bioavailability of isoflavones, making them easier to digest, and shows promising results without side effects.
Liver specialists recommend screening high-risk patients for cirrhosis due to its growing prevalence as a cause of death, but others argue that the test's accuracy and cost-effectiveness are questionable. Implementing widespread screening could lead to disinvestment in other interventions and risks population health.
A new study reveals that high school principals have a significant impact on creating academic policies for students recovering from concussion. While many protocols exist for returning to sports, principals can help ease students back into their normal routine with accommodations such as frequent breaks and quiet testing environments.
A new USC-led study reveals that Medicare Advantage plans pay physicians similar prices to traditional Medicare, with most procedures seeing reimbursement rates near parity. The researchers also found that commercial insurance pays higher prices for many services.
Scientists have identified three inflammatory biomarkers that can detect traumatic brain injury (TBI) within hours of occurrence. The discovery could lead to the development of a test for diagnosing TBI on the sidelines of sports pitches or by paramedics, allowing for timely treatment and reduced disability.
A change in cervical cancer screening guidelines led to a decrease in Pap testing and chlamydia testing among young women. Chlamydia testing declined by 26% in females aged 15-19, resulting in lower reported incidence rates for this age group.
A study by Johns Hopkins Medicine suggests that on-site pill-testing services can reduce the risks associated with recreational drug use. The researchers found that people are more likely to reject taking a pill if it contains harmful additives or is adulterated.
The EPICUP® test, based on DNA analysis, can correctly diagnose CUP in 70% of cases, increasing the detection rate from traditional methods' 30%. This leads to the development of more specific treatments for these patients.
A simple test for bladder cancer has been developed that can predict its return in over 80% of patients, identifying the faulty protein TERT. This new method detects bladder cancers earlier than existing tests and distinguishes them from urinary tract infections, potentially helping doctors start treatment sooner.
Researchers expose newborn mice to isoflurane, a widely used anesthetic agent, and find chronic activation of the mTOR pathway, which affects normal brain development. The study reveals abnormal neuron structure and impaired learning abilities in mice exposed to isoflurane.
Researchers have adapted a diagnostic test for malaria to predict post-treatment anemia risk with 89% sensitivity and 73% specificity. The BinaxNOW malaria kit measures HRP2 remnants on red blood cells, offering a potential alternative to mandatory monitoring for high-risk patients.
A new portable device can quickly detect markers of deadly sepsis infection from a single drop of blood, providing rapid point-of-care measurement of the immune system's response. The device correlates well with traditional tests and vital signs, offering potential for earlier detection and prognosis.
A new study found that EPO blood doping has little effect on high-intensity laboratory cycling tests and endurance road-race performances. However, the drug was associated with increased risk of thrombosis due to elevated haemoglobin and adhesion molecule levels.
A new paradigm of empathy-based medicine is needed to improve patient outcomes and reduce practitioner burnout. Technology can exploit available technologies to gather basic information prior to consultation and aid decision-making.
Researchers at the University of Notre Dame have developed a novel platform using nanoparticles to detect peanut allergies. The technology mimics natural allergens and evaluates the potency of allergic responses using antibodies from patient blood samples.
A simple blood test measuring carcinoembryonic antigen (CEA) levels could change treatment options for 17% of stage 2 colon cancer patients. The test may improve survival rates and quality of life for thousands with the disease.
A study using Neuro Kinetics' I-Portal devices found that a battery of OVRT tests can accurately measure concussion symptoms both initially and during recovery. The study suggests that these tests may be used to monitor subacute concussion recovery and help determine the safest time for patients to return to activities.
The task force ranked tests into three tiers according to the strength of the recommendation for average-risk people. Colonoscopy is highly sensitive for cancer and precancerous lesions, while fecal immunochemical testing (FIT) is non-invasive and lower-cost but must be repeated annually. The new guidelines also recommend starting scre...
Researchers have developed a diagnostic test for amyotrophic lateral sclerosis (ALS) using neurofilaments, which can confirm the presence of the disease. The test has shown promising results in accurately diagnosing ALS patients, with a good correlation between neurofilament levels and motor neuron loss.
Exposure to just 10 minutes of light at night suppresses biting behavior and manipulates flight in Anopheles gambiae mosquitoes. The study suggests pulses of light could be an effective tool to complement established control methods for reducing disease transmission.
Researchers at Université de Genève have developed a new test to detect anti-phospholipid antibody syndrome (APS), an autoimmune disease affecting around 0.5% of the population. The test targets the specific antibody that binds to cells, producing pro-inflammatory and pro-thrombotic factors, offering improved accuracy and standardization.
Physicians' adherence to H. pylori guidelines is low, with only 58% checking for eradication after treatment. A higher proportion of physicians are treating patients after a positive test, but antibiotic resistance remains a concern.
Researchers at George Washington University are testing a candidate recombinant hookworm vaccine in a Phase II clinical trial. The study aims to prove the efficacy of the vaccine against hookworm infection and its potential benefits for millions of people infected worldwide.
A study published in Academic Emergency Medicine found that the level of benefit, risk, and cost significantly influence patients' decisions to receive a diagnostic test. The researchers discovered that participants were more likely to accept a diagnostic test when the cost was lower, highlighting the impact of financial burden on medi...
A large pragmatic trial found that checking finger-stick blood sugars did not offer significant advantages in blood sugar control or quality of life for non-insulin treated type 2 diabetes patients. The study suggests that the costs of home blood glucose monitoring may outweigh its benefits for this population.
Researchers at EPFL developed a dynamic test method that replicates blood and lymphatic systems, allowing for more accurate nanoparticle testing. This method reduces discrepancies between in vitro and in vivo tests, providing valuable insights into nanoparticle behavior.
A new assay developed by University of Illinois researchers can identify Palmer amaranth DNA in mixed seed samples, overcoming slow and unreliable testing methods. The low-cost technique uses quantitative PCR to detect genetic variations unique to Palmer, enabling farmers to certify their product as Palmer-free.
The new guideline provides practical advice on key areas, including diagnostic algorithms, treatment advice, and risk assessment. Patients will benefit from receiving evidence-based advice to reduce accidental reactions and manage reactions more effectively.
A new enhanced test, EQUC, detects significantly more bacteria in urine samples than the standard culture, leading to improved diagnosis and treatment of urinary tract infections. The study enrolled 150 urogynecologic patients and found that EQUC identified 110 species of bacteria, while the standard culture only identified 50 percent ...
The Consensus Document from the American Society of Addiction Medicine (ASAM) offers practical guidance on drug testing in various clinical settings. It emphasizes that drug testing should be widely used to monitor adherence and abstinence, but also serves as a therapeutic tool rather than a punitive one.
UCSB biologists develop new antimicrobial susceptibility test that mimics conditions in the body, identifying effective treatments for diverse bacteria. The revised test has significant implications for public health, allowing physicians to choose alternative drugs immediately if a standard test fails.
A molecule produced by a Thai liver parasite has been found to have the potential to supercharge healing and treat non-healing wounds in diabetics. The researchers have successfully produced a version of the molecule on a large enough scale to conduct laboratory tests, with promising results.
A new paper-based test strip could enable doctors and patients to monitor heart failure conditions at home, using smartphone apps for analysis. The test strip detects antigens ST2 and BNP, providing insights into the progression of the disease.
Researchers at Lawson Health Research Institute and Western University found that dual gait testing can predict dementia progression in seniors with mild cognitive impairment. The study showed that individuals with slower gait speeds while performing a cognitively demanding task are at higher risk of progressing to dementia.
A recent study found that a cancer drug called ibrutinib can reduce allergic skin test reactivity by 80-90% in patients with certain types of leukemia and lymphoma. The treatment also showed promise in preventing reactions to common airborne allergens, such as cat dander and ragweed.
A school-based intervention and podcast targeting parents improved children's ability to assess health claims, with over twice as many students in the intervention group achieving a passing score compared to those in control groups. The studies focused on 12 key concepts, including the reliability of anecdotes and conflicting interests.
A national patient safety effort led to a significant reduction in urinary tract infections related to catheters in nursing homes. The study shows that implementing a toolkit of training materials and coaching support can lead to improved catheter care and infection prevention.
Researchers have created a TaqMan-Based Multiplex real-time PCR detection system to rapidly diagnose sepsis, increasing the chance of targeting the correct agent and avoiding antibiotic misuse. The test detects 10 frequent bacterial pathogens from blood samples and can even identify pathogens in blood culture-negative cases.
Researchers discovered a link between a donor and infection in heart, lung transplant recipients caused by Mycoplasma hominis. The bacteria resists most antibiotics and can cause serious complications like pleurisy, surgical site infections, and mediastinitis.
Researchers found that a strategy combining personalized support and decision-making tools increased screening rates among patients at community health centers. 68% of participants were screened for colorectal cancer within 6 months, compared to 27% without the intervention.
A decision aid and support strategy increased screening completion among patients with historically lower screening rates, with 68% screened for colorectal cancer within six months. The intervention provided clear information about screening options and personalized support, facilitating shared decision-making with physicians.
A new study reveals that diesel vehicles worldwide exceed emissions standards by 4.6 million tons, resulting in 38,000 premature deaths each year. The findings emphasize the need for stricter emission certification tests and real-world compliance measures to improve air quality.