Articles tagged with Personalized Medicine
New studies explore peptide receptor radionuclide therapy, targeted radiation for prostate cancer, and neuroendocrine tumor treatment. Targeted radiation boosts survival in colorectal liver cancer and bone metastases, while a new PET imaging tracer shows promise for detection.
A new smartphone app, ECHAS, can help people determine if they are suffering from a heart attack or stroke and need medical attention. The app, developed by experts at UVA Health and other leading institutions, proved effective in identifying patients with cardiac and neurological emergencies.
A new combination therapy pairing radiopharmaceutical 177Lu-DOTATATE with DNA-repair blocker olaparib has been deemed feasible and tolerable for neuroendocrine cancer patients. Eighteen patients received the combined therapy, resulting in a 69% disease control rate at six months.
A new study reveals that Aspergillus fumigatus infection can unbalance the lungs by creating a microaerophilic niche for bacteria like Ligilactobacillus murinus. This interaction may influence disease progression and enable new treatment approaches, highlighting the importance of understanding the gut-lung axis.
Researchers identified metabolite patterns in blood and urine related to ultra-processed food intake. A poly-metabolite score was developed, showing potential to objectively measure diet and reduce reliance on self-reported data.
A new study by Queen Mary University of London found significant ethnic differences in breast cancer development and outcomes among women of African and South Asian genetic ancestry. Women from these backgrounds were diagnosed earlier and died younger than European-ancestry women, highlighting the need for tailored care approaches.
A new technique using focused sound waves and microbubbles has shown great promise in treating debilitating brain lesions called cerebral cavernous malformations. The approach has halted the growth of lesions almost entirely, offering a potential paradigm shift in treatment.
A new study found that a simple oral swab test can increase IVF success rates by identifying the best hormone treatment for each woman based on her genetic profile. The test, developed by researchers at Lund University, shows promise in reducing costs and increasing pregnancies.
The University of Texas at Arlington offers pre-health students valuable hands-on experience through an innovative collaboration. Students in SCIE 4304 participate in immersive clinical simulation lab at the UTA Smart Hospital, developing rudimentary clinical skills and overcoming imposter syndrome.
The Human Exposome is a global scientific effort to understand the environmental factors that underpin disease and health. The Exposome Moonshot Forum aims to chart this exposome, providing usable metrics and data points for targeted public health interventions.
Serum Krebs von den Lungen-6 (KL-6) levels are significantly elevated in patients with interstitial lung disease (ILD), suggesting its potential as a diagnostic biomarker. The study also highlights the relationship between KL-6 levels and pulmonary function, specifically forced vital capacity.
A new study reveals a significant increase in ischemic heart disease prevalence across Southeast Asia, East Asia, and Oceania between 1990-2021. The regions experience distinct risk factors, including air pollution, dietary patterns, and high blood pressure.
A new survey by the Physicians Committee for Responsible Medicine reveals that half of U.S. adults believe a plant-based diet improves their health and prevents chronic diseases. Only 20% of primary care practitioners discuss this with patients, highlighting a missed opportunity to turn interest into action and reduce disease risk.
A groundbreaking study from the University of Virginia Health System reveals distinct immune patterns in patients with persistent breathing issues after COVID-19. The research identifies specific T cell changes linked to lung damage and fibrosis, paving the way for personalized treatments.
The journal is seeking submissions to a new theme issue exploring the importance of telerehabilitation and future directions for the field. Researchers will focus on implementation challenges, health equity concerns, and emerging innovations like AI-driven personalized rehabilitation.
Scientists at Henry Ford Health + Michigan State University Health Sciences have identified a circulating microRNA called miR-126-3p as a mechanistic biomarker of knee osteoarthritis. This discovery may lead to the development of blood tests for early detection and therapeutics for slowing or stopping disease progression.
Researchers at TUM developed an AI-powered algorithm to predict kidney damage in prostate cancer patients undergoing lutetium-177 PSMA therapy. Early detection could enable personalized treatment adjustments to prevent organ damage.
A UT Health San Antonio-led discovery could redefine drug discovery by turning IV medications into orally administered treatments for brain cancer, Alzheimer’s disease, and other complex conditions. The new strategy uses a protein receptor called CD36 to efficiently deliver large molecules into cells.
The University of Missouri is partnering with a consortium to design and license a new research reactor, NextGen MURR, which will produce critical medical isotopes for cancer treatment. The project aims to enhance Missouri's role as a leader in nuclear science and medical research.
Researchers developed fluorescent polyionic nanoclays that can be customized for medical imaging, sensor technology, and environmental protection. These tiny clay-based materials exhibit high brightness and versatility, enabling precise tuning of optical properties.
Researchers used data from 9,000 pregnancies to discover and validate RNA signatures that distinguish between severe and mild hypertensive disorders of pregnancy. The study validates Mirvie's simple blood test to predict preeclampsia early, at 17.5-22 weeks gestational age.
Aging (Aging-US) journal announces a commemorative collection honoring Dr. Mikhail Blagosklonny, a pioneer in aging biology. The special issue will explore key themes central to his scientific contributions, including mechanistic insights and translational approaches.
A new Electronic Frailty Index 2 (eFI2) system will improve the accuracy of identifying older people's frailty by integrating data on 36 health problems. This will enable GPs to provide personalized treatments to prevent costly loss of independence and falls in older age.
Researchers at Lancaster University discovered a new type of vaccine-specific scepticism, where some people perceive COVID-19 vaccines as 'not a vaccine' compared to MMR. This phenomenon may also apply to the flu vaccine, highlighting the need for clear public health messaging.
Researchers developed a new diagnostic platform that classifies brain tumors based on the body's cancer-fighting immune response. The approach tailors treatment options to each patient's unique immune profile, offering improved diagnostics and potential for immunotherapies to revolutionize childhood leukemia treatments.
A new theme issue in the Canadian Journal of Cardiology emphasizes the importance of personalized heart health advice considering individual differences. The issue highlights disparities in sports participation and related health outcomes between males and females as well as socioeconomic disparities, with women showing a lower risk of...
Fentanyl poisoning among US children has surged by 924% and 1,506% for teens aged 13-19 over the past eight years. Parents are advised to be vigilant about hidden fentanyl risks and know the signs of overdose symptoms to save their children.
A new study found that the proportion of visceral fat, rather than the absolute amount, is a stronger predictor of high triglyceride levels and inflammation. Lowering visceral fat proportion during weight loss can lead to better metabolic health outcomes.
The new AI model leverages hypergraphs to quickly and accurately identify therapeutic gene targets for diseases. HIT outperformed existing models in all tested metrics, demonstrating its accuracy in classifying therapeutic gene targets with great precision.
La Jolla Institute scientists found that a protein in brain cells drives Parkinson's onset and may explain why the disease is more common in men. PINK1 appears to mark brain cells for immune cell attack, leading to inflammation and death.
Researchers introduce a dual threshold classifier to interpret circulating tumor DNA levels, enabling earlier detection of disease progression and personalized treatment. The study confirms that ctDNA levels are superior to traditional biomarkers like CA15-3.
A recent MSU study highlights the challenges of diagnosing episodic disabilities like epilepsy, where symptoms fluctuate and can be unpredictable. The research found that 52% of participants experienced delayed diagnoses, while others faced quick confirmations within days of their first seizure.
Researchers at the Institute for Systems Biology (ISB) have developed a breakthrough method to track diet using stool metagenomic data. The MEDI approach detects food-derived DNA in stool samples to estimate dietary intake, offering a convenient alternative to traditional methods that suffer from misreporting and compliance issues.
A new study from the University of Texas at Arlington found that Americans aged 65 and older who experienced parental divorce as children were more likely to suffer a stroke compared to their peers. The study analyzed data from over 13,000 older Americans and found that about 14% had experienced parental divorce during childhood.
A large study found that telemedicine and training apps had minimal positive effects on patients with type 2 diabetes and coronary heart disease. The study suggests that direct care from medical professionals remains crucial for improving health outcomes in this population.
A groundbreaking study analyzed data from over 78,000 cancer patients to identify nearly 800 genetic changes impacting survival outcomes. The research also discovered genes significantly associated with survival in various cancers, such as breast, ovarian, skin, and gastrointestinal cancers.
Researchers developed a breakthrough technology using Mirvie's RNA platform to identify unique molecular signals in unborn babies. This innovation enables prediction of severe fetal growth restriction, a leading cause of stillbirth.
A national survey of 1,008 Americans found that nearly two-thirds use a device to monitor their heart health, but only one in four shares the data with their doctor. This lack of sharing can lead to delayed diagnosis and treatment, emphasizing the importance of proactive communication between patients and healthcare providers.
Researchers developed a system to monitor tumor-informed circulating tumor DNA (ctDNA) after comprehensive genomic profiling (CGP), enabling accurate prediction of patient outcomes. The study showed that this approach can be effectively used in conjunction with CGP data to predict cancer relapse and treatment response, improving person...
A team of researchers developed a web-based system called 'DeepMerkel' to predict Merkel cell carcinoma treatment specific outcomes based on personal and tumour specific features. The system was able to accurately identify high-risk patients at an earlier stage, enabling informed clinical decision making and improved patient choice.
The University of Plymouth and International Osteopathic Education have formed a partnership to provide a comprehensive Master of Osteopathic Medicine program. The five-year program offers flexible study, clinical teaching in France and international partner clinics, and prepares students for an interdisciplinary practice.
Researchers analyzed individual cells from two craniopharyngioma subtypes to identify specific cell types, their features, and interactions. The study found distinct cell types linked to tumor development and immune response in both adamantinomatous and papillary craniopharyngiomas.
Researchers have developed a new generation of cell-penetrating antibodies that can target cancer cells and deliver therapeutic molecules directly into tumor cells. The 3E10 antibody shows great promise for treating cancers with defective DNA repair pathways.
A groundbreaking study has established the world's largest and most geographically comprehensive international norms for handgrip strength, covering 2.4 million adults from 69 countries. The new norms enable global peer-comparison, health screening, and surveillance across the adult lifespan, helping clinicians identify people at risk ...
A team of UNC-Chapel Hill researchers will develop an oncology health learning system using AI-ready data to generate real-time identification of new cancer cases and support personalized treatments. The project aims to improve cancer diagnosis, care equity, and quality by creating accessible tools for health providers.
A 10-minute brain scan can predict the effectiveness of a risky spinal surgery to alleviate intractable pain. The study found that patients who responded better to spinal cord stimulation therapy had weaker connections between certain brain networks.
A new study reveals that patients with Parkinson's disease who exhibit rest tremor have more dopamine preserved in the caudate nucleus, a part of the brain important for movement planning and cognition. This challenges traditional understanding of how dopamine loss relates to PD symptoms.
A new study introduces the PWAS Hub, a powerful tool that explores gene-disease connections across 99 common diseases. The platform identifies genes linked to specific conditions and provides valuable genetic insights for clinicians and researchers.
A new study by uOttawa highlights the importance of providing culturally and linguistically concordant care to avoid inappropriate prescribing of antipsychotics. Francophone and Allophone residents are more likely to experience inappropriateness compared to English-language patients.
The C-Path initiative aims to generate drug development solutions that reflect each person's unique experience, leveraging diverse data and innovative technologies like AI and digital health. GEM-PD seeks to address unmet need in Parkinson's disease therapies by focusing on sex and gender differences.
The new CAMP 2.0 tool provides personalized medicine for managing allergic contact dermatitis by generating safe lists based on individual patch testing results. It offers thousands of product options and interactive tools to help patients find safe products, track their quality of life, and understand their allergens.
The CRISPR tool was successfully used to correct a genetic defect in cells affected by chronic granulomatous disease. However, the repair process also introduced new genetic defects, highlighting the need for caution when using CRISPR technology in clinical settings.
Researchers develop transcranial ultrasound stimulation (TUS) as a non-invasive therapy for brain-related issues, with potential for personalized treatments. A 'search and rescue tool' for the brain, TUS enables precise targeting of specific areas before treatment.
Scientists have developed a new method using artificial intelligence to design thousands of DNA switches that can activate or repress genes in specific cell types. This approach could revolutionize gene therapy and biotechnology by allowing precise control over gene expression in the body.
Researchers have made a breakthrough in understanding the rare autoimmune disease anti-NMDAR encephalitis, which can cause psychosis, hallucinations, and blackouts. The study found that different antibodies bind to NMDA receptors in unique ways, suggesting personalized medicine may be key to treating the condition.
A peer-reviewed study published in NEJM Catalyst found Waymark's early intervention model significantly improved clinical outcomes for patients receiving Medicaid, reducing hospital and ED visits by 22.9%. The study also showed improved patient goal completion and care quality.
A study from Lehigh University and Seattle University found that making patients aware of biases in human healthcare decisions increases receptiveness to AI recommendations. By highlighting the limitations of human judgment, healthcare providers can create a more balanced relationship between patients and emerging technologies.
A longitudinal study tracked one person's brain activity for five months, revealing how daily life affects brain function. The research found that physical activity positively influences brain regions, while subtle shifts in mood and heart rate leave lasting imprints for up to fifteen days.
A new technique called Clonal competition assays helps understand the evolutionary advantages of multiple myeloma cells over available treatments. It allows researchers to see how each population of cells in the same myeloma reacts to treatments, getting closer to understanding heterogeneity and resistance.
Researchers have developed a new treatment for deep diabetic foot ulcers, using intact fish skin grafts to promote healing. The study found that this innovative approach showed promising results in improving wound closure and reducing infection rates.