Articles tagged with Breast Cancer
A study found that removing 2mm around invasive breast cancer tumors reduces residual disease in 98% of patients, according to a research published in the International Journal of Clinical Practice. The study also showed that patients with non-invasive cancer have higher rates of residual disease.
A genetic test predicting early menopause risk could help UK women in their 30s plan families. Researchers identified four genes associated with early menopause and found they combined to have a larger impact on the condition.
African American women with higher vegetable intake have a lower risk of developing estrogen receptor-negative breast cancer. High cruciferous and carrot consumption may play a role in reducing breast cancer risk through their effects on estrogen metabolism and antioxidant properties.
A significant proportion of patients with advanced cancer receive common cancer screenings, despite the limited benefit. Screening rates are higher among those with a recent history of screening and in those with higher socioeconomic status and married status.
A study of postmenopausal women found that engaging in a healthy lifestyle reduces breast cancer risk for those with and without a family history. Women who adhered to regular physical activity, maintained a healthy weight, and drank less alcohol had lower rates of invasive breast cancer.
Researchers at Fox Chase Cancer Center found that the loss of protein Nedd9 initially slows cancer formation but then makes tumors more aggressive. A class of drugs already used in clinics can make these aggressive tumors more sensitive to treatment.
Regular physical activity, maintaining a healthy weight, and reducing alcohol consumption lower breast cancer risk for women with and without a family history of the disease. A study of over 85,000 postmenopausal women found that these behaviors significantly reduce breast cancer risk.
Researchers found that targeting epidermal growth factor receptor (EGFR) provides substantial clinical benefit for women with hard-to-treat triple-negative breast cancer. Adding cetuximab to chemotherapy doubled response rate and time to progression compared to chemotherapy alone.
The AACR will honor two leading breast cancer researchers, Klaus Pantel and Alan Ashworth, for their groundbreaking work on detection and treatment of breast cancer. Pantel will receive the Outstanding Investigator Award for his pioneering research on minimal residual disease, while Ashworth will deliver the Distinguished Lectureship f...
A study published in Cancer found that racial disparities in breast cancer care persist, even after accounting for patients' insurance and socioeconomic status. Black and Hispanic women are less likely to receive recommended treatments compared to white women.
The final phase-II results show that iniparib plus chemotherapy significantly improves overall survival from 7.7 to 12.3 months, offering a promising new treatment option for metastatic triple-negative breast cancer patients. Over half of patients experience clinical benefit, and there is little increase in adverse events.
A new meta-analysis shows that continuing chemotherapy after bringing cancer under control can increase survival time and reduce disease progression in metastatic breast cancer patients. The analysis found a 34% reduction in disease progression and a 9% reduction in death rates for patients who received longer chemotherapy durations.
A study of Italian women with breast cancer found that most cases were diagnosed in people over 50 and had not spread to lymph nodes. The disease was hormone-receptor positive and HER2-negative, indicating a classical endocrine-responsive type. Treatment choices were influenced by tumor stage rather than biological factors.
A study by Dr. Hatem Azim found that breastfeeding is safe for women after breast cancer treatment, contrary to common advice. Successful long-term breastfeeding was associated with type of breast surgery and post-delivery lactation counseling.
Scientists at the University of Illinois Chicago have found a gene expression mechanism that contributes to drug resistance in aggressive ER-positive breast tumors. The study reveals how estrogen and inflammatory proteins work together to drive cancer progression.
A new Montreal study suggests a link between air pollution from traffic and an increased risk of post-menopausal breast cancer. The study found that women living in areas with high levels of nitrogen dioxide, a by-product of vehicular traffic, were more likely to develop breast cancer.
A retrospective cohort study of 983 women found that non-Hispanic black and Hispanic women experienced significantly longer diagnostic delays than white women, regardless of insurance status. Diagnostic delay times ranged from 11.9 to 70.8 days, with uninsured black women facing the longest waits.
Researchers found that Puerto Rican women with triple-negative breast cancer had a higher risk of death from breast cancer, even after adjusting for age and cancer stage. Women under 50 years old with regional/distant disease were also more likely to die from their breast cancer.
A study found that Mexican women who are exposed to environmental tobacco smoke are at a higher risk of developing breast cancer, with a threefold increased risk compared to those who do not smoke. The link between passive smoking and breast cancer remained regardless of menopausal status.
Computer-aided detection (CAD) software highlighted abnormal areas on mammographic images, used in 74% of screening exams and 50% of diagnostic exams by 2008. The technology is becoming standard practice despite controversy over its efficacy.
A study published by the American Association for Cancer Research found that vigorous exercise of more than two hours per week can significantly reduce the risk of developing breast cancer in postmenopausal African-American women. Women who engaged in such exercise had a 64% reduced risk compared to those who did not.
A group-based, holistic mind-body intervention was found to be equally effective in treating persistent fatigue and improving quality of life for breast cancer survivors across different racial groups. The program combined relaxation techniques, nutrition optimization, physical activity, and cognitive behavioral therapy.
A landmark study found that annual mammography screenings for women aged 40-49 reduces breast cancer deaths by nearly 30%. The results confirm that age 50 as a screening threshold is unfounded, and women should begin getting annual mammograms at age 40.
A study by the University of Melbourne found that close relatives of women diagnosed with breast cancer before age 35 have a higher risk of developing other cancers. These include prostate, lung, brain, and urinary tract cancers, with increased risks ranging from 2 to 8 times higher than expected.
A team of researchers led by Ellen Velie aims to identify risk factors for breast cancer in young women, particularly black women younger than 50. The five-year study will investigate the impact of early life growth patterns, physical activity, diet, and body size on tumor characteristics.
Seth Field, a UC San Diego researcher, has been awarded $3.86 million to study GOLPH3's role in breast cancer. His project aims to understand the mechanism by which GOLPH3 contributes to cancer and develop new therapy targets.
Researchers at Indiana University School of Medicine found gray matter changes in breast cancer patients' brains during and after chemotherapy treatment. Memory and executive functions were most affected, with some women experiencing subtle and others severe cognitive impairments.
Researchers identified insulin-like growth factor 1 receptor (IGF-1R) overexpression in 25% of triple-negative breast cancers, correlated with gene amplification. IGF-1R blockade has been successful in sarcomas, and targeting this receptor may offer new therapeutic options for triple-negative breast cancer.
Researchers have identified a single biomarker that may predict resistance to tivozanib in patients with kidney and breast cancer. The biomarker reflects the presence of white blood cells inside tumors and is associated with clinical activity.
A new disposable device based on microfluidics can efficiently capture cancer cells overexpressing HER2, enabling therapy with trastuzumab. The device offers a non-invasive alternative to current methodologies and has shown promising results in early studies.
Researchers found that circulating tumor cells (CTCs) can provide real-time information on patient's current disease state through biomarker assessments. The technology has potential for non-invasive detection and analysis of cancer biomarkers.
A new analysis reveals that male partners of women with breast cancer are at a significantly higher risk of developing severe mood disorders requiring hospitalization. The study found a 39% increased risk of being hospitalized with an affective disorder among men whose partners had breast cancer, compared to those without.
The National Cancer Institute has awarded a five-year, $13.6 million grant to the University of North Carolina at Chapel Hill's Carolina Center of Cancer Nanotechnology Excellence to improve cancer diagnosis and treatment through nanotechnology advances. The grant will support research efforts led by Dr. Joseph DeSimone and Dr. Joel Te...
A Mayo Clinic collaboration identified four genetic variants on chromosome 14 associated with aromatase inhibitor-induced arthritis. These findings provide a new clue for identifying women at risk and developing treatments, allowing more women to take lifesaving breast cancer therapy.
A new study published in the Journal of the National Cancer Institute found that breast cancer survivors with physical limitations are more likely to die from other diseases due to poorer health. Regular physical activity can reduce the risk of breast cancer recurrence and improve survival rates.
A study analyzing Canadian data shows a decline in breast cancer incidence among postmenopausal women as hormone therapy prescriptions fell. The decline, which coincided with a drop in hormone replacement therapy use, suggests that HRT may be linked to an increased risk of breast cancer.
A new study published in the Journal of Sexual Medicine found that 70% of women are facing sexual function problems approximately two years post-diagnosis. The study suggests that specific treatments for breast cancer, such as aromatase inhibitors, can exacerbate menopausal symptoms leading to sexual problems.
A study found that breast cancer survivors with functional limitations affecting motion, strength, and dexterity are at risk of dying from other causes, but not breast cancer recurrence. The study highlights the importance of addressing physical limitations in cancer survivorship plans.
This special issue examines the ways cancer treatment affects cardiovascular function and overall survival, highlighting key challenges and potential strategies for minimizing collateral damage. Key findings include the need for cardiac outcomes data and evidence-based practice guidelines to mitigate heart-related complications.
Studies identified that postmastectomy irradiation triples the risk for an unplanned return to the operating room and immediate breast reconstruction increases that risk eight-fold. Women considering immediate reconstruction may benefit from a sentinel lymph node biopsy prior to mastectomy.
Researchers identified five genetic variants associated with increased breast cancer risk in BRCA1 carriers, including those related to estrogen-receptor-negative and triple-negative disease. These findings may help identify individuals at lower or higher risk of cancer, enabling tailored cancer prevention strategies.
A new material can mark early-stage tumors using ultrasound imaging, potentially reducing the need for second surgeries and making operations more comfortable for patients. The durable material is made of porous glass spheres filled with a gas that helps it last longer.
A new study found that girls without a biological father are more likely to enter puberty at an earlier age, especially in higher-income households. The study suggests that familial and contextual factors play an important role in the onset of puberty.
Marshall University researchers Dr. Elaine Hardman and Dr. Philippe Georgel have received over $1 million in federal funding to study the effects of omega-3 fatty acids on breast cancer development, particularly in female offspring. They aim to identify genetic changes associated with a maternal diet rich in omega-3 fatty acids and dev...
A new study has found that alcohol consumption after a breast cancer diagnosis may increase the risk of cancer recurrence. The study followed 1,897 women with early-stage breast cancer and found that those who consumed 3 to 4 drinks per week had a higher risk of breast cancer recurrence and death compared to non-drinkers.
Research found that chronic stress increases cancer spread by 30-fold in stressed mice compared to unstressed controls. Stress alters the biology of immune cells, promoting metastasis to distant organs. Beta blockers blocked this effect, suggesting potential prevention strategies.
Women with secondary breast cancer face inadequate support due to lack of knowledge, experience and staff numbers among healthcare professionals. Better training, resources, and services are needed to address this complex condition.
The study found that radiation exposure increases the risk of both first and second cancers to a similar degree, with higher risks for radiation-sensitive cancers like lung, colon, breast, thyroid, and bladder cancers. Cancer survivors with a history of radiation exposure should continue to be closely monitored for second cancers.
Hilary Calvert, Alberto Costa, and Bengt Glimelius received the 2010 ESMO Award for their significant work in breast cancer development, multidisciplinary care, and gastrointestinal cancer treatment. The awards recognize their contributions to advancing medical research and improving patient outcomes.
A study led by Professor Graham Packham of the University of Southampton shows that watercress compounds can block a critical pathway linked to cancer development. The research found that eating watercress may interfere with the function of protein HIF, which plays a role in tumor growth.
A team of researchers from the University of Illinois will investigate the health effects of botanical estrogens, including phytoestrogens from soy and other plants. The study aims to determine whether these compounds have beneficial or detrimental effects on human health.
Researchers developed a Monte Carlo analysis tool to optimize X-ray mammography, improving image quality and reducing radiation dose. The algorithm may also detect cancerous tissue in breasts automatically.
A long-term study found that women with BRCA1 and BRCA2 genetic mutations significantly reduced their risk of breast and ovarian cancer with preventive surgeries. Risk-reducing mastectomies and removal of the fallopian tubes and ovaries lowered cancer risks, including those with prior breast cancer.
A recent study found that Mexican-origin women are more likely to be diagnosed with breast cancer at younger ages and have higher mortality rates than non-Hispanic white women. The research highlights the need for tailored prevention and education strategies to address these disparities.
A new study finds that when plastic surgeons are involved in the initial treatment decision-making process, women are more likely to receive breast reconstruction. The study highlights the importance of discussing reconstruction options with a plastic surgeon and emphasizes the need for comprehensive care coordination.
Women with a family history of breast or ovarian cancer can benefit from prophylactic surgeries to remove ovaries, fallopian tubes, or breasts, increasing survival rates and eliminating risk. Genetic testing is crucial for identifying the BRCA1 and BRCA2 genes, which significantly increase cancer risk.
Research at Michigan State University's Breast Cancer and the Environment Research Center found that a high-fat diet during puberty can lead to inflammation in the mammary glands, promoting breast cancer growth. The study suggests that this link may be independent of obesity.
Prophylactic mastectomy and salpingo-oophorectomy significantly reduce breast and ovarian cancer risks in women with BRCA1/2 mutations. The study found that risk-reducing mastectomy decreased breast cancer risk, while salpingo-oophorectomy lowered ovarian cancer risk.
Two newer breast imaging technologies, BSGI and PEM, have been approved for clinical use despite higher cancer risks. The lifetime risk of radiation-induced cancer from BSGI and PEM exams are significantly higher than digital mammography, with estimated risks ranging from 20 to 30 times higher.
A study published in The Journal of the National Cancer Institute found that alcohol consumption is more strongly related to the risk of lobular carcinoma than ductal carcinoma, and more strongly related to hormone-receptor-positive breast cancer than hormone-receptor-negative breast cancer.