Articles tagged with Breast Cancer
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The National Cancer Institute has awarded a five-year, $13.6 million grant to the University of North Carolina at Chapel Hill's Carolina Center of Cancer Nanotechnology Excellence to improve cancer diagnosis and treatment through nanotechnology advances. The grant will support research efforts led by Dr. Joseph DeSimone and Dr. Joel Te...
A Mayo Clinic collaboration identified four genetic variants on chromosome 14 associated with aromatase inhibitor-induced arthritis. These findings provide a new clue for identifying women at risk and developing treatments, allowing more women to take lifesaving breast cancer therapy.
A new study published in the Journal of the National Cancer Institute found that breast cancer survivors with physical limitations are more likely to die from other diseases due to poorer health. Regular physical activity can reduce the risk of breast cancer recurrence and improve survival rates.
A study analyzing Canadian data shows a decline in breast cancer incidence among postmenopausal women as hormone therapy prescriptions fell. The decline, which coincided with a drop in hormone replacement therapy use, suggests that HRT may be linked to an increased risk of breast cancer.
A new study published in the Journal of Sexual Medicine found that 70% of women are facing sexual function problems approximately two years post-diagnosis. The study suggests that specific treatments for breast cancer, such as aromatase inhibitors, can exacerbate menopausal symptoms leading to sexual problems.
A study found that breast cancer survivors with functional limitations affecting motion, strength, and dexterity are at risk of dying from other causes, but not breast cancer recurrence. The study highlights the importance of addressing physical limitations in cancer survivorship plans.
This special issue examines the ways cancer treatment affects cardiovascular function and overall survival, highlighting key challenges and potential strategies for minimizing collateral damage. Key findings include the need for cardiac outcomes data and evidence-based practice guidelines to mitigate heart-related complications.
Studies identified that postmastectomy irradiation triples the risk for an unplanned return to the operating room and immediate breast reconstruction increases that risk eight-fold. Women considering immediate reconstruction may benefit from a sentinel lymph node biopsy prior to mastectomy.
Researchers identified five genetic variants associated with increased breast cancer risk in BRCA1 carriers, including those related to estrogen-receptor-negative and triple-negative disease. These findings may help identify individuals at lower or higher risk of cancer, enabling tailored cancer prevention strategies.
A new material can mark early-stage tumors using ultrasound imaging, potentially reducing the need for second surgeries and making operations more comfortable for patients. The durable material is made of porous glass spheres filled with a gas that helps it last longer.
A new study found that girls without a biological father are more likely to enter puberty at an earlier age, especially in higher-income households. The study suggests that familial and contextual factors play an important role in the onset of puberty.
Marshall University researchers Dr. Elaine Hardman and Dr. Philippe Georgel have received over $1 million in federal funding to study the effects of omega-3 fatty acids on breast cancer development, particularly in female offspring. They aim to identify genetic changes associated with a maternal diet rich in omega-3 fatty acids and dev...
A new study has found that alcohol consumption after a breast cancer diagnosis may increase the risk of cancer recurrence. The study followed 1,897 women with early-stage breast cancer and found that those who consumed 3 to 4 drinks per week had a higher risk of breast cancer recurrence and death compared to non-drinkers.
Research found that chronic stress increases cancer spread by 30-fold in stressed mice compared to unstressed controls. Stress alters the biology of immune cells, promoting metastasis to distant organs. Beta blockers blocked this effect, suggesting potential prevention strategies.
Women with secondary breast cancer face inadequate support due to lack of knowledge, experience and staff numbers among healthcare professionals. Better training, resources, and services are needed to address this complex condition.
The study found that radiation exposure increases the risk of both first and second cancers to a similar degree, with higher risks for radiation-sensitive cancers like lung, colon, breast, thyroid, and bladder cancers. Cancer survivors with a history of radiation exposure should continue to be closely monitored for second cancers.
Hilary Calvert, Alberto Costa, and Bengt Glimelius received the 2010 ESMO Award for their significant work in breast cancer development, multidisciplinary care, and gastrointestinal cancer treatment. The awards recognize their contributions to advancing medical research and improving patient outcomes.
A study led by Professor Graham Packham of the University of Southampton shows that watercress compounds can block a critical pathway linked to cancer development. The research found that eating watercress may interfere with the function of protein HIF, which plays a role in tumor growth.
A team of researchers from the University of Illinois will investigate the health effects of botanical estrogens, including phytoestrogens from soy and other plants. The study aims to determine whether these compounds have beneficial or detrimental effects on human health.
Researchers developed a Monte Carlo analysis tool to optimize X-ray mammography, improving image quality and reducing radiation dose. The algorithm may also detect cancerous tissue in breasts automatically.
A long-term study found that women with BRCA1 and BRCA2 genetic mutations significantly reduced their risk of breast and ovarian cancer with preventive surgeries. Risk-reducing mastectomies and removal of the fallopian tubes and ovaries lowered cancer risks, including those with prior breast cancer.
A recent study found that Mexican-origin women are more likely to be diagnosed with breast cancer at younger ages and have higher mortality rates than non-Hispanic white women. The research highlights the need for tailored prevention and education strategies to address these disparities.
A new study finds that when plastic surgeons are involved in the initial treatment decision-making process, women are more likely to receive breast reconstruction. The study highlights the importance of discussing reconstruction options with a plastic surgeon and emphasizes the need for comprehensive care coordination.
Women with a family history of breast or ovarian cancer can benefit from prophylactic surgeries to remove ovaries, fallopian tubes, or breasts, increasing survival rates and eliminating risk. Genetic testing is crucial for identifying the BRCA1 and BRCA2 genes, which significantly increase cancer risk.
Research at Michigan State University's Breast Cancer and the Environment Research Center found that a high-fat diet during puberty can lead to inflammation in the mammary glands, promoting breast cancer growth. The study suggests that this link may be independent of obesity.
Prophylactic mastectomy and salpingo-oophorectomy significantly reduce breast and ovarian cancer risks in women with BRCA1/2 mutations. The study found that risk-reducing mastectomy decreased breast cancer risk, while salpingo-oophorectomy lowered ovarian cancer risk.
Two newer breast imaging technologies, BSGI and PEM, have been approved for clinical use despite higher cancer risks. The lifetime risk of radiation-induced cancer from BSGI and PEM exams are significantly higher than digital mammography, with estimated risks ranging from 20 to 30 times higher.
A study published in The Journal of the National Cancer Institute found that alcohol consumption is more strongly related to the risk of lobular carcinoma than ductal carcinoma, and more strongly related to hormone-receptor-positive breast cancer than hormone-receptor-negative breast cancer.
Researchers have purified the protein produced by the breast cancer susceptibility gene BRCA2, opening new possibilities for understanding, diagnosing, and treating breast cancer. The protein plays a role in repairing damaged DNA, acting as a mediator to help another protein associate with a single strand of DNA.
A phase 3 trial found trastuzumab improves median survival to 13.8 months for HER2-positive advanced gastric cancer patients, with a 26% reduction in death rate compared to chemotherapy alone. The treatment's cost effectiveness is questioned due to its estimated £13,857 per patient cost and $55,000 cost per life-year gained.
A recent study led by University of Alberta researcher Margie McNeely found that only five percent of breast cancer survivors are at risk of developing arm swelling due to air travel. The research involved 60 Canadian women who flew to Australia and showed that 95% had no arm swelling.
Indiana University-Purdue University Indianapolis researchers have developed a new methodology to improve identification of breast cancer tissue by pathology laboratories. Their work, recognized internationally, has been selected as the best scientific paper in the
Scientists have discovered an accomplice in breast cancer – a master control switch with the power to set off a cascade of reactions orchestrated by a cancer-causing gene named Wnt1. The executive molecule MTA1 is reported to trigger cancer-causing signals from Wnt1 in human breast cancer cells, leading to tumors.
A recent study by University of Alberta research fellow Amy Speed-Andrews found that Iyengar yoga improved physical and mental health in breast cancer survivors. The 10-week program showed significant reductions in stress, anxiety, and depression, with participants experiencing improvements in quality of life and overall well-being.
A newly formed advisory committee will review all federal breast cancer research efforts and develop recommendations for improving existing programs. The committee aims to expand opportunities for collaborative, multi-disciplinary research and advance the understanding of links between environment, genes, and health.
Researchers at the University of Gothenburg have identified 12 genes linked to aggressive breast cancer, which could lead to more reliable prognoses and better treatment strategies. The study found that these genes are associated with an increased risk of tumor progression, cell growth, motility, and development.
A recent study suggests that a new drug, Olaparib, can reduce tumor size in women with advanced hereditary ovarian and breast cancers, offering a promising targeted therapy approach. The Phase II trials showed significant shrinkage in tumor size and relatively mild toxicities.
Researchers compared four progestins and found that N-EL and N-One strongly inhibited tumor development, while MPA promoted it. Progestins like N-EL and N-One may have potential as preventive agents in women with no breast disease or family history.
Researchers develop a new method to target cancer tumors using heat and magnets, reducing side effects and damage to healthy tissue. The innovative technique uses biomarkers attached to individual tumors and excites nano-particles with an external magnetic field, killing the tumor cells.
A researcher is studying a gene that may contribute to aggressive breast cancer. If successful, the study could lead to new treatments for the disease.
A Kansas State University research team is investigating the mutated ADAM12 gene's role in breast cancer, with findings suggesting its high expression in cancer stem cells. This discovery could lead to more targeted therapies, as conventional treatments often fail on these aggressive cells.
Researchers at Wake Forest University Baptist Medical Center found that low ferroportin levels are associated with aggressive and recurring breast cancers. Testing ferroportin levels may help predict cancer return and guide therapy for patients.
Researchers found that African American women who use oral contraceptives are more likely to develop estrogen receptor negative breast cancer. The study, based on data from the Black Women's Health Study, also revealed a significant increase in risk for women who have used oral contraceptives for 10 or more years.
Researchers developed an alphavirus vector to overcome neutralizing antibodies and induce immune responses in humans with advanced cancer. Genetic mutations determined breast cancer subtype by influencing Rb gene expression.
Researchers found that epigenetic profiles of tumors had a direct association with diet, alcohol, and tumor size, providing new biomarkers for disease subtype and severity. The study's data show promise for tumor epigenetic signatures to provide more detailed tumor staging and prediction of prognosis.
A study led by researchers at the University of Louisville found that individuals with a male first-degree relative with breast cancer perceive themselves as being at higher risk than those with a female relative. However, many lack awareness and discussion about genetic testing.
A study published in JAMA found that a genetic risk score is strongly associated with an increased risk of breast cancer and can predict the type of disease. The researchers identified specific genes that have different effects on different subtypes of breast cancer.
A team of researchers led by Dr. Kerry Courneya will investigate the impact of physical activity on breast cancer outcomes in a five-year study. The study aims to explore how physical fitness levels affect disease recurrence, treatment completion, and quality of life in women with breast cancer.
A study found that mammographic tumor detectability decreases with age, primarily due to denser breast tissue masking tumors. The study suggests that lowered mammographic tumor detectability accounts for 79% of the poorer sensitivity in mammography screening among younger women.
The Marilyn B. Gula Mountains of Hope Foundation has donated $50,000 to the Translational Genomics Research Institute (TGen) for advanced breast cancer research and treatment. The donation will support groundbreaking research into the genetic components of common and complex diseases, including advanced breast cancer.
The GRB7 gene is found to drive an aggressive form of breast cancer and acts independently of the HER-2 gene. Isolating its role could help fine-tune treatment and enable accurate prognoses.
Researchers found that African women are more likely to develop triple-negative breast cancer, a condition characterized by the absence of estrogen and progesterone receptors. The study suggests that African ancestry may be associated with a higher risk of hereditary predisposition for breast cancer related to BRCA1 gene mutations.
Researchers found that women who used more air fresheners and products for mold and mildew control had a higher incidence of breast cancer. The study suggests that cleaning products may contribute to breast cancer risk, highlighting the need for further investigation into this potential link.
A three-year clinical study will examine the relationship between physical function decline and age-related disparities in breast cancer treatment. The study aims to develop a well-validated instrument for measuring functional decline among senior adults with cancer, ultimately improving breast cancer outcomes for older women.
Two new studies have tested three different methods for accurately measuring breast density. A third technique called dual-energy mammography showed promise in measuring breast density. The researchers hope to use this method to improve the accuracy of breast cancer risk assessments.
A study analyzed the probability of surviving nine types of cancer in Spain, comparing rates to European averages. The results show varying survival rates for different cancers, with some types having high recovery rates (e.g., testicular and skin melanoma) while others have lower rates (e.g., lung cancer).
Researchers at Northwestern University developed a new arsenic nanoparticle that effectively targets and blocks aggressive triple negative breast cancer. The nanoparticles deliver the toxic cargo directly to tumor cells while shielding normal tissue from harm, making it a promising lead for improving chemotherapy drugs.
The Samuel Waxman Cancer Research Foundation has awarded 13 collaborative and 3 individual research grants worth $1.54 million to top scientists exploring cancer differentiation therapy. The recipients are experts in reprogramming cancer cells, with a focus on finding new treatments for various types of cancer.
The European Society for Medical Oncology (ESMO) has published updated clinical practice guidelines for cancer care, providing vital information on diagnosis, treatment plans, and follow-up. The new guidelines cover various tumor types and include expanded sections on cardiotoxicity and fertility considerations.
Researchers have successfully induced epigenetic reprogramming in human and mouse breast cancer cells, making them more susceptible to tamoxifen treatment. This targeted epigenetic therapy has shown promising results in reversing the growth and invasive properties of triple-negative breast cancer cells.