Articles tagged with Breast Cancer
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A new study of 50,000 people found that heavy smoking leads to a higher risk of premature death, particularly among men and women. The study also highlighted the benefits of quitting smoking early, with those who quit experiencing greater health benefits and longevity.
A study of 252 women found that those with higher breast volume asymmetry were more likely to develop breast cancer. The research suggests that breast asymmetry could be a reliable indicator of future breast disease and is an independent predictor of breast cancer.
A study published in the Journal of Clinical Oncology found that women with breast cancer who undergo preventive mastectomies are satisfied with their decision and have a lower risk of developing future breast cancer. The survey also revealed that concerns about breast cancer were more common among women without the procedure.
A study of 3,828 older women diagnosed with stage I or II breast cancer found that mammography rates were significantly higher among those receiving shared care, which included primary care physicians and specialists. The study suggests that this approach can lead to better quality care for breast cancer survivors.
A large epidemiological study led by Xiao-Ou Shu found significant improvements in survival and quality of life measures among breast cancer patients who used ginseng, particularly those who started using it before diagnosis. The study suggests that ginseng may provide tangible benefits to breast cancer survivors.
The study found that the percentage of women receiving adjuvant chemotherapy who received taxanes such as paclitaxel increased more than sevenfold after early 1998, with rates rising in both node-positive and node-negative breast cancer. The authors suggest that publicity at ASCO and media coverage contributed to this shift.
The FACTT technology has a sensitivity five orders of magnitude greater than ELISA, allowing for the detection of rare molecules at early stages. This new method holds promise for detecting abnormalities in diseases such as breast, ovarian, and pancreatic cancer.
The center will investigate disparities in modifiable risk factors for breast cancer, particularly among African-American women, and examine demographic, lifestyle, medical, and genetic profiles for obesity. The research aims to develop predictive models and biomarkers to improve early detection and treatment of breast cancer.
A national analysis of local TV news health coverage reveals opportunities for improvement in accuracy and perspective. The study found that health and medical stories comprised 11% of late-evening newscasts, but often lacked specific information about disease prevalence and prevention methods.
A recent study published in Radiology found that nearly a quarter of benign papillary breast lesions were upgraded to atypical ductal hyperplasia or ductal carcinoma in situ after surgical excision. This suggests that these lesions should be surgically removed to prevent potential cancer development.
Robert A. Weinberg's work on human oncogenes led to understanding cancer's mechanisms of invasion and progression. Angela M. Hartley Brodie developed aromatase inhibitors to prevent breast cancer recurrence in postmenopausal women.
The article discusses the potential link between aluminum salts in deodorants and breast cancer. Researchers believe that exposure to these metals through antiperspirant use may increase breast cancer risk due to their oestrogenic activity.
Researchers found that Ginkgo biloba extract significantly slowed the growth of aggressive breast tumors in mice by 80 percent, while also reducing brain tumor size. The study suggests that Ginkgo biloba may have preventive effects on invasive cancers and is being explored as a potential treatment for Alzheimer's disease.
The incidence of breast cancer in Korea is increasing, with a significant rise in the proportion of asymptomatic patients detected by mammography. This trend reflects the country's westernization and lower breastfeeding rates, leading to higher risk factors such as early menarche and obesity.
Current support systems for men with breast cancer are rudimentary, highlighting the need for national protocols that provide information and emotional support. Risk factors include occupational exposure to high temperatures, genetic abnormalities, and excess alcohol, which increase the risk of the disease.
A population-based case-control study found that women using medium potency estrogen-progestin combination therapy had a higher risk of developing lobular or tubular breast cancer. The risk was more pronounced for those who used the therapy for over five years, with a notable increase in the incidence of tubular and lobular cancers.
Parallel administration of chemotherapy and darbepoetin alfa every 3 weeks is safe and effective in treating anemia. Gene expression profiling may provide more accurate information for certain high-risk breast cancers than laboratory examination alone.
Researchers found that most sporadic basal-like breast cancers display abnormalities in the management of the X chromosome, leading to increased expression of specific genes. This defect may contribute to cancer development and progression in these aggressive subtypes.
A comprehensive breast cancer protein library has been established, enabling researchers to study proteins' roles in cancer development. The library's vast collection of cDNAs covers a broad spectrum of breast cancer-related genes, offering new avenues for understanding and treating the disease.
A large study published in JAMA Network found that a low-fat diet had no significant impact on the incidence of invasive breast cancer in postmenopausal women. The Women's Health Initiative Dietary Modification Trial involved 48,835 women and followed their dietary habits over an 8.1-year period.
A low-fat diet was associated with a 15% reduction in estradiol levels and a 30% risk reduction for a certain subtype of breast cancer. The study also found no significant impact on heart disease, but trends toward reduction were seen among women who made the greatest reduction in saturated fat and trans fat consumption.
A study of nearly 49,000 postmenopausal women found a modest reduction in breast cancer incidence among those with high fat intake, but this benefit was not seen in those who reduced their fat intake. Women should focus on reducing saturated and trans fats, increasing vegetable consumption, and maintaining regular exercise for overall ...
Researchers found that post-lactation involution matrix promotes breast tumor cell migration and metastasis, even when compared to virgin matrix. The study suggests changes in the breast environment during pregnancy may contribute to poor breast cancer outcomes.
Researchers found that overexpression of Nod1 inhibits estrogen-dependent tumor growth in human breast cancer cells, leading to reduced tumor formation and growth. The study suggests a new mechanism for controlling estrogen-sensitive breast cancers and opens the door for future development of novel therapeutics.
UF researchers identified a gene called focal adhesion kinase (FAK) that produces an enzyme creating a protective barrier for cancer cells. Blocking this interaction with protein VEGFR-3 kills malignant cells. The findings open new avenues for improved cancer therapies.
Researchers developed a method to analyze molecular markers in breast cancer cells using flow cytometry, enabling rapid prognosis and treatment decision-making. This technology holds promise for various solid tumors, including colon, ovarian, prostate, and gastric cancers.
PET imaging has shown to be a valuable tool in improving cancer care management by accurately assessing treatment outcomes and monitoring tumor response. Studies have demonstrated that PET can detect residual scar tissue rather than viable tumor, leading to changes in how PET is used in cancer care.
Researchers found that STAT1 is a critical survival pathway in head and neck cancer, with increased levels leading to diminished and dying cancer cells. Therapeutic strategies to restore its functioning may be beneficial for patients, potentially improving treatment outcomes and survival rates.
The study found that regular use of selective COX-2 inhibitors significantly reduced the risk of breast cancer. Daily doses of celecoxib (83% reduction) and rofecoxib (64% reduction) had a more significant impact on reducing the risk.
Researchers have identified a new pathway for cancer treatment by targeting the degradation of steroid receptor coactivator 3 (SRC3) through the REG-GAMMA molecule. High levels of SRC3 can lead to tumor growth in breast cancer, but low levels of REG-GAMMA can activate its destruction, potentially halting tumor progression.
A study has found that vaginal oestrogen can increase systemic oestradiol levels in women on aromatase inhibitors (AI) for breast cancer, potentially counteracting AI treatment. Researchers recommend avoiding the combination of AIs and vaginal oestrogens, except in exceptional circumstances.
Researchers are investigating delivering chemotherapy drugs directly to breast ducts to treat early breast cancer. Studies in rats and mice show promising results, with tumors shrinking or disappearing after treatment. The procedure aims to minimize disfigurement and spare normal tissues.
Belgian and Italian researchers developed a new imaging technique that can predict breast cancer patients' response to hormonal treatment with high accuracy. The technique uses 99mTc-depreotide scintigraphy to assess hormone sensitivity in tumors, allowing for early selection of patients likely to benefit from hormonal therapy.
A recent study found that active participants in online breast cancer support groups reported more positive physical, psychological, and social status. They also experienced fewer concerns about breast cancer and higher perceptions of family support. The study suggests that women with closer relationships to their families are more inc...
Researchers have identified a growth control flaw in some aggressive breast cancers, linked to overactive cyclin D1 and CDK4 kinase. The finding could pave the way for new therapies targeting this deadly subtype of breast cancer.
Research on women with HIV found that those infected with both HIV and high-risk HPV were at greatest risk of developing cervical cancer precursors. A study on postmenopausal women found sex hormone levels to be not associated with breast cancer risk, while another study suggested that BRCA2 mutation carriers had a fourfold increased i...
A study of 9059 breast cancer patients found that older women had less complete medical records, larger tumors, and fewer lymph nodes examined. As a result, they received less effective treatments, such as radiotherapy and chemotherapy, compared to younger patients.
A study found that high doses of soy isoflavones can block the effects of estrogen in postmenopausal women, potentially reducing breast cancer risk. Women with higher estrogen levels may benefit from a diet rich in soy isoflavones.
Researchers at OHSU have discovered a protein fragment, p95HER-2, which closely correlates with lymph node metastasis and earlier recurrence of breast cancer. The study suggests that p95HER-2 is a marker for metastasis and may help identify patients with longer disease-free survival.
A recent study published in Integrative Cancer Therapies found that dogs can detect breast and lung cancer with sensitivity and specificity rates of 88-97%. The trained dogs were able to identify cancers even in early stages, providing a potential reduction in uncertainty in cancer diagnosis.
A study published in JCI Journal reveals that alpha-basic-crystallin is overexpressed in breast cancer tumors and triggers tumor development. The protein causes dysregulated growth, changes in cell structure, and diminished programmed cell death, ultimately leading to poor clinical outcomes.
Researchers found that mice fed a soy-based diet had significantly worse heart problems than those on a milk protein-based diet. This is the first study to show an environmental influence can affect the heart.
A study found that hospitals performing few breast cancer operations a year have high readmission rates and poorer outcomes. Experts agree that breast cancer surgery requires significant surgical expertise.
Researchers found alphaB-crystallin protein promotes uncontrolled growth in breast cancer cells, suggesting it as a molecular marker for aggressive breast cancer. The study identified a key pathway activated by alphaB-crystallin and found drug inhibitors block its effects, paving the way for new targeted therapies.
Researchers have discovered that breast stem cells with genetic errors can produce tumours even after chemotherapy. The discovery could lead to the development of new treatments targeting these faulty stem cells.
A meta-analysis of randomized controlled trials found that statins did not reduce the incidence of cancer or cancer death. The study evaluated 86,936 participants and 26 trials, with no reductions noted for specific types of cancer.
A meta-analysis of 36 clinical trials reveals that optimal radiation therapy significantly improves patient survival rates in breast cancer patients. The analysis found a 2.9% and 6.4% absolute increase in survival at 5 and 10 years, respectively.
UCSD researchers found a strong association between vitamin D deficiency and higher rates of colon, breast, and ovarian cancers. They recommend increasing the public's intake of vitamin D3 to 1,000 IU/day to reduce cancer incidence, which could lead to thousands of premature deaths annually.
A study by Washington University psychologist Teresa L. Deshields found that most breast cancer survivors adjust well to survivorship within two weeks, with depressive symptoms dropping significantly after treatment. The study suggests that oncologists can reassure patients that their quality of life will improve quickly.
A study of 574 women who underwent postmastectomy breast reconstruction found that 31% developed at least one adverse event, with common complications including infection, blood clotting, and seroma. Additional surgery was required for 21%, while reimplantations also showed similar rates of complications.
A new study published in Cancer Research found that artificial light at night can stimulate the growth of human breast cancer cells in laboratory mice. The researchers discovered that melatonin, a hormone produced by the brain, plays a key role in regulating tumor growth and development.
Researchers found that artemisinin reduced breast tumors by 39% and inhibited tumor growth. The study suggests artemisinin's anti-malarial properties may also target cancer cells due to their high iron uptake.
Women with the CYP2D6 genetic variant were more likely to experience breast cancer recurrence when treated with tamoxifen. Researchers also found that this group was less likely to suffer from hot flashes, which may predict the gene variation.
A new study found that radiotherapy significantly reduces breast cancer mortality and local recurrence rates, particularly in women with lymph node involvement. Radiotherapy can improve long-term survival, especially for those with a history of breast-conserving surgery or mastectomy.
Preliminary results from the study show that E7389 induces partial responses in patients with refractory breast cancer. The predominant serious side effect was neutropenia, but mild to moderate side effects were also reported.
A pilot study found that pairing low-dose chemotherapy with the anti-VEGF antibody bevacizumab delayed breast cancer progression by an average of 5.5 months compared to low-dose chemotherapy alone. The combination therapy showed better results, with 29% partial responses and 41% stable disease.
A new study by BCIRG shows that Herceptin paired with chemotherapy significantly improves disease-free survival in early breast cancer patients, while eliminating cardiac toxicity. The treatment also reduces the risk of relapse by 51% and is an alternative to standard therapy for patients at risk of heart damage.
A large study found an increased risk of second cancers in various sites, including connective tissue and myeloid leukemia, after breast cancer diagnosis. Treatment for breast cancer and shared genetic or environmental factors are thought to contribute to this risk.
A randomized clinical trial of dose-dense chemotherapy in early-stage breast cancer found the regimen to be safe, with a 13% reduced risk of death. However, the dose-dense treatment increased acute toxic effects such as anemia and bone pain, but these were mild and easy to manage.
Researchers at UC Davis found breast CT images to be equivalent and potentially better than standard mammography for detecting breast cancer. The technology requires no breast compression and uses similar radiation doses as mammography.