Research on diseases of the heart and blood vessels. Covers microvascular imaging, light exposure, cardiac imaging anxiety, and sex differences in risk.
A study by Wake Forest School of Medicine identified a dead probiotic strain that reduces age-related leaky gut and inflammation in older mice. The dead probiotic strain, Lactobacillus paracasei D3-5, extended the lifespan of roundworms and improved physical and cognitive functions in mice.
The study, published in The Lancet, analyzed data from almost 400,000 people and found a strong link between non-HDL cholesterol levels and long-term cardiovascular disease risk in those under 45. Reducing cholesterol levels by half may lower the risk of heart disease or stroke by up to 60% for some individuals.
A new study led by St. Michael's Hospital researchers found that different types of sugars showed varying associations with cardiovascular disease. Higher intake of total or fructose-containing sugars was linked to increased death from cardiovascular disease, while higher sucrose intake was associated with decreased mortality.
A recent study published in JMIR Mental Health found that internet-based therapy significantly reduced depression in CVD patients, leading to improved quality of life. The treatment involved nine weeks of online cognitive behavioural therapy, with access to a nurse via the web, resulting in clinical improvements for one in five patients.
A review of randomized controlled trials found that pharmacist-led interventions, such as medication review and patient education, can help prevent cardiovascular disease. Patients who received these interventions experienced significant reductions in systolic blood pressure, hemoglobin A1c, and LDL-cholesterol levels.
Researchers found that recovering from metabolic syndrome significantly reduced the risk of cardiovascular disease in a nationwide population-based cohort study. In contrast, developing or remaining in metabolic syndrome was associated with an increased risk of cardiovascular disease.
A recent review of prospective cohort studies found that consuming legumes reduces incidence rates for cardiovascular disease, coronary heart disease, and hypertension by up to 10%. Legumes benefit cardiovascular health due to their high fiber, plant protein, and micronutrient content.
Researchers led by Dr. Stanley Hazen will explore how gut microbes convert digested nutrients into chemical signals, affecting cardiovascular and metabolic diseases. The team aims to identify specific microbial pathways linked to atherosclerosis, thrombosis, and obesity.
Researchers at Karolinska Institutet identified antisense oligonucleotide therapies as a new possible treatment option for progeria. In mice and human cells, the treatments showed promising results by reducing telomeric non-coding RNA and improving cell division.
Cardiovascular disease in women often presents differently than in men and may not be diagnosed. Barbra Streisand joins Noel Bairey Merz, director of the Women's Heart Center at Cedars-Sinai, to discuss these key differences.
A recent study by the University of California, Davis Health, found that nearly 10% of middle-age and older Latinos in the US meet the criteria for mild cognitive impairment. Factors such as cardiovascular disease and depression were identified as risk factors for MCI.
A new study has found that early menopause is associated with a higher risk of developing cardiovascular diseases. The observational study revealed a significant increase in cardiovascular events among women who experienced natural premature menopause or surgery-induced menopause before age 40.
Research highlights the disproportionate impact of diabetes on women, with a higher risk of cardiovascular death and heart failure compared to men. Healthy lifestyle habits and glucose-lowering treatment are crucial in preventing these complications.
A review article highlights traditional and emerging cardiac-specific biomarkers to identify early risk factors for cardiovascular disease in childhood obesity. These biomarkers, such as cardiac troponins and natriuretic peptides, may help target treatment to high-risk individuals, reducing the risk of adult-onset cardiovascular disease.
Researchers implemented the Northeast Health Equity Consortium to address heart disease and stroke disparities in at-risk communities. The initiative helped states achieve major goals for eliminating health disparities, including over one million free blood pressure screenings.
A 10-year study found that middle-aged men with higher muscle mass had a lower risk of heart attack and stroke. The researchers suggest that preserving skeletal muscle mass through regular physical activity and a protein-rich diet may help reduce cardiovascular disease risk.
Researchers from SingHealth Duke-NUS Institute of Precision Medicine linked chronic sleep deprivation to increased cardiovascular disease risk markers and accelerated biological aging. Volunteers who slept less than five hours a night had shorter telomeres, which are thought to represent cellular age.
Research links depression to increased odds of heart disease and stroke, with a 24% increase in risk for each additional level of depression severity. The study analyzed data from over 11,000 adults diagnosed with depression and found a significant association between depression and non-fatal heart disease.
A new study reveals that people with cardiovascular disease are at higher risk of developing cancer, while those with more risk factors for heart disease are also more likely to develop cancer. Lifestyle habits that reduce heart disease risk, such as a healthy diet and regular exercise, may also help prevent some cancers.
A pooled analysis of 14 studies involving over 232,000 people found that any amount of running significantly lowers the risk of death from all causes. Even small doses of running, such as once weekly or less than 50 minutes, are associated with significant health and longevity benefits.
Research finds high-intensity sporting physical activity improves neural baroreflex, while physical activity at work is associated with abnormal neural baroreflex and greater arterial stiffness. Chronic, strenuous activity at work may pose a risk to cardiovascular health.
A Mayo Clinic-led study found that microvascular endothelial dysfunction is associated with a greater than twofold risk of cancer. The condition, which affects the heart's small arteries, may be a useful marker for predicting cancer risk.
Researchers have identified a new therapeutic target for treating cardiovascular disease by studying the role of the TRIB1 protein in immune cells. The study found that higher levels of TRIB1 increased cholesterol uptake in foam cells, promoting arterial disease.
Scientists at UVA aim to uncover the origin and development of coronary heart disease using a genetic variation associated with ID3 gene, with potential for personalized treatments based on patient's genotype
The National Institute on Aging has funded a major study to examine the benefits and risks of cholesterol-lowering drugs known as statins in adults age 75 or older. The trial, called PREVENTABLE, aims to determine whether statin therapy can help prevent dementia and disability in this age group.
A faulty signalling pathway is linked to left ventricular non-compaction (LVNC), a congenital heart condition where muscular projections fail to transform into compact heart muscle. The study provides new insights into the molecular mechanisms underlying LVNC and may lead to potential therapies.
A study of Canadian women found that those with bulimia nervosa were at higher risk for long-term cardiovascular disease and death. The study, which followed participants for 12 years, also revealed a significant association between bulimia and increased mortality rates.
For most healthy individuals, statin use is uncertain and its benefits are small, while potential harms exist. The research suggests that lower-risk groups may not reach acceptable levels of risk reduction to justify taking daily statins.
Between 2000 and 2015, the number of US deaths from cardiovascular disease among people aged 25 to 64 rose substantially. This trend is attributed to increased rates of heart disease and stroke.
Researchers at WVU are using artificial intelligence to develop more efficient and accurate diagnoses of cardiovascular diseases, potentially leading to cost savings and improved patient outcomes. The four-year project aims to address research challenges associated with AI in healthcare, including data analysis efficiency and privacy m...
A significant association between changes in income and cardiovascular disease (CVD) risk was found in this observational study. Participants who experienced a 50% or more decrease in income were at higher risk of developing CVD, including heart attack, coronary heart disease, and stroke, over an average follow-up period of 17 years.
A new study in the Canadian Journal of Cardiology shows that older individuals have the most to gain from rehabilitation programs and may benefit the most. Regular exercise improves physical capacity, anxiety, and depression in patients with cardiovascular disease, regardless of age.
A high fiber diet significantly improves cardiovascular risk factors, including cholesterol, triglycerides, blood pressure, and fasting glucose. Researchers found a protective role of fiber against cardiovascular disease in patients with hypertension and Type 2 diabetes.
Adults with tooth loss due to nontraumatic events are more prone to heart attacks and strokes. Researchers analyzed 316,588 US participants aged 40-79, finding a significant association between oral health and cardiovascular disease.
Women who reach menopause before age 50 are at higher risk of cardiovascular disease, according to researchers from The University of Queensland. Early menopause is associated with a 40% increase in cardiovascular conditions and nearly twice the likelihood of non-fatal cardiac events.
A simple cardiac risk score is associated with MRI-detected pre-clinical cerebrovascular disease, including carotid artery plaque and silent strokes. Early detection and treatment of cardiovascular risk factors can prevent cerebrovascular disease from developing.
Researchers at the University of Helsinki have identified 35 genetic loci associated with plasma lipid species levels, revealing a significant heritable component in cardiovascular disease risk. The study also highlights the potential of lipidomics to improve cardiovascular risk prediction and treatment.
This study examined changes in internal medicine subspecialty choices from 1991 to 2016, with women and men showing varying trends across nine subspecialties. The findings suggest shifting interests in areas like geriatric medicine and hematology and oncology, potentially driven by demographic changes.
A major population study found that genetic variants associated with educational attainment also lower the risk of cardiovascular disease. These variants have implications for a healthier lifestyle, regardless of education level.
A single pill containing low doses of three medications reduced blood pressure and cholesterol levels in a US study, translating to a 25% lower risk of cardiovascular disease. The study enrolled mostly low-income, primarily black adults from Mobile, Alabama, and showed high adherence rates.
A study found that cardiovascular disease risk prediction algorithms may underestimate the risk for people with severe mental illness, often defined as schizophrenia, bipolar disorder, and major depression. The algorithm consistently underestimated cardiovascular disease rates in this group, particularly in women.
A new study found that even short-term reduction in physical activity led to decreased cardiorespiratory fitness, increased waist circumference, and insulin resistance in healthy adults. Resuming normal activity levels reversed these effects, highlighting the importance of staying physically active to offset negative consequences.
A comprehensive study from Uppsala University found that deep belly fat is a major risk factor for developing diabetes and cardiovascular disease in women. The researchers developed a simpler method to estimate visceral fat content, which may be useful for healthcare.
A study of 3,462 residents in Lausanne, Switzerland found that taking a weekly daytime nap reduced the risk of heart attack or stroke by 48%. The frequency, not just the duration, of naps is what matters, researchers suggest. This new insight may help explain previous conflicting findings on the health benefits of napping.
A new study found that NYC firefighters' exposure to 9/11 World Trade Center dust is associated with a significantly increased long-term risk of cardiovascular disease. Those who arrived first at the site have a 44% higher risk of experiencing primary and secondary CVD events compared to those who arrived later.
A study of nearly 9,800 NY firefighters suggests an association between greater exposure to the World Trade Center disaster and long-term cardiovascular disease risk. Both acute and repeated exposure during work at the site are linked to higher cardiovascular disease risk compared to those with less exposure.
Researchers at Thomas Jefferson University have discovered two gene variations that may modulate platelet cell behavior and affect the risk of developing cardiovascular disease. The study suggests that these genetic variants could be potential targets for modulating expression of CD36, a key regulator of platelet levels and activation.
Researchers will examine biomarkers and chemicals in thirdhand smoke to understand its impact on cardiovascular health. The five-year study aims to design better therapies for thirdhand smoke-induced cardiovascular disease.
A recent study found that eating nuts at least twice a week is associated with a lower risk of death from cardiovascular disease. The researchers analyzed data from 5,432 Iranian adults and found that nut consumption was linked to a 17% reduced risk of fatal heart attack and stroke.
The guidelines emphasize healthy behaviors, such as physical activity and a Mediterranean diet, to prevent cardiovascular disease. They also recommend specific medications, including GLP-1 receptor agonists and PCSK9 inhibitors, for patients with diabetes at high risk of cardiovascular disease.
A study of nearly half a million people found that those with heart or blood vessel problems benefited more from having a physically active lifestyle than healthy people without cardiovascular disease. Increased physical activity reduced the risk of dying during a six-year follow-up period for people with and without CVD.
A study of nearly 8,800 individuals found that quitting heavy smoking lowers the risk of cardiovascular disease within five years, but this benefit diminishes after 10 to 15 years compared to never-smokers. The analysis suggests a long-term risk premium for former smokers, limiting the generalizability of findings
Researchers explore ultrasound therapy's effectiveness in treating various cardiovascular conditions, including hypertension and arrhythmia. The study highlights the benefits of acoustic intervention, including deep tissue penetration and minimal invasiveness.
This observational study found that individuals with higher daytime and nighttime systolic blood pressure levels had an increased risk for cardiovascular events and death, independent of clinic-measured blood pressure. The findings suggest monitoring blood pressure outside the clinic during a 24-hour period may help identify African Am...
Researchers found a significant association between elevated post-exercise troponin levels and an increased risk of severe cardiovascular disease or death. The study suggests that exercise may serve as a stress test for the heart, allowing for early identification of susceptible individuals who require closer monitoring.
A new study found that NSAIDs contribute to cardiovascular side effects in individuals with osteoarthritis, increasing the risk of heart failure, ischemic heart disease, and stroke by 42%, 17%, and 14% respectively. The study suggests that patients with OA should discuss the risks and benefits of NSAID use with their care providers.
Researchers analyzed food intake data from over 10,000 middle-aged adults and found a strong link between plant-based diets and lower cardiovascular disease risks. People who ate more plant-based foods had a 16% lower risk of cardiovascular disease and a 32% lower risk of dying from any cause.
Research finds heart disease and stroke mortality rates are barely declining or increasing in 12 high-income countries since 2000. Obesity levels may be a significant contributor to the slowdown.
Research from the University of Copenhagen found that remnant particle cholesterol in the blood is constantly increasing and often remains at a high level for life. Maintaining a normal body weight is key to reducing remnant cholesterol and triglycerides, according to experts.
Scientists developed a technique to study heart disease in action, enabling them to identify ways to lower plaque-forming lipoproteins. The LipoGlo system allows researchers to measure lipoproteins in tiny droplets of blood, opening up new avenues for treating cardiovascular disease.