Articles tagged with Coronary Artery Disease
A study published in JAMA Cardiology found that prolonged dual antiplatelet therapy reduces the risk of death, heart attack, or stroke in patients with peripheral arterial disease undergoing percutaneous coronary intervention. Concomitant PAD is associated with a 2-fold increased risk of ischemic events, but not bleeding.
A new study published by the European Society of Cardiology found that an active strategy of detecting and treating asymptomatic multisite artery disease did not improve 2-year outcomes compared to a traditional approach. The study enrolled 521 CAD patients and found no significant difference in all-cause mortality, rehospitalization f...
Researchers from Mount Sinai and international partners have identified specific genes that contribute to cardiometabolic diseases, such as heart attack and stroke. The study analyzed gene-expression data from patients with coronary artery disease and found genes that regulate blood lipid levels in abdominal fat.
The study highlights the importance of managing pericardial effusions, myocardial disease, pulmonary arterial hypertension, and other cardiac complications in HIV-infected patients. Clinicians must be aware of these manifestations, diagnosis, and treatment options to improve patient outcomes.
A Finnish study found that nearly 60% of patients with coronary artery disease also had dental root tip infections. The researchers discovered a strong link between the two conditions, suggesting that oral infections may contribute to heart disease risk. Root canal treatment may help reduce this risk.
A study of over 23,000 patients found that women had a lower risk of comorbidities and experienced fewer vascular complications in-hospital after TAVR. Despite this, women's one-year survival rate was still higher than men's.
A study by Brigham and Women's Hospital identifies four factors contributing to sex disparities in statin therapy among patients with coronary artery disease. Women were less likely to start or continue statin therapy due to lower cardiologist evaluations and higher rates of adverse reaction reports.
A study found that familial hypercholesterolemia mutations account for less than 2% of cases with severely elevated LDL levels, but significantly increase the risk of coronary artery disease. Gene sequencing identified individuals at high risk who may benefit from additional preventive therapies.
Women experiencing suspected heart disease exhibit similar classic symptoms to men, including chest pain and shortness of breath, but differ in diagnosis and risk assessment. The study found that women have more risk factors for heart disease than men, yet are often assessed as lower risk.
A study of over 287,000 patients found that African-American patients with connective tissue diseases like lupus and rheumatoid arthritis were twice as likely to develop narrowed or atherosclerotic blood vessels. Young African-Americans with CTD also had a higher risk of cardiovascular disease, including heart attacks and strokes.
A randomized controlled study published in Annals of Internal Medicine found that providing information about coronary artery disease risk to patients undergoing genetic testing for Alzheimer's disease improved health behaviors and reduced distress. The study suggests that the disclosure of secondary findings from genomic testing can h...
The American College of Physicians (ACP) offers guidance on evaluating blood in the urine, emphasizing the importance of referring patients with gross hematuria and confirming heme-positive results. For adults with microscopically confirmed hematuria, urology referral for cystoscopy and imaging is recommended.
A recent study found that depression is strongly associated with the frequency of chest pain in adults with and without underlying coronary artery disease. Patients with depression were three times more likely to experience more frequent chest pain than those without depression.
Patients without obstructive CAD are just as likely to experience angina after a heart attack as those with obstructive CAD. Non-invasive strategies to reduce angina burden could significantly impact patients' health and quality of life.
Researchers found that coronary artery calcification scans can accurately predict all-cause mortality up to 15 years in asymptomatic patients. The study's findings suggest that CAC scanning could help physicians identify patients at risk for early death and advise them to adopt healthier lifestyles.
Patients who viewed images of their calcified coronary arteries were more likely to stop smoking, lose weight and take statins. The study suggests that visualising health threats motivates patients to make changes, reducing plasma cholesterol levels and other risk factors.
3D simulations analyze local flow fields and identify correlation between left coronary angulation and wall shear stress changes. CFD complements cardiac CT imaging by defining internal biomechanics, including stresses and strain within the coronary artery system.
A study found that peanut consumption with a high-fat meal improved post-meal triglyceride response and preserved endothelial function in overweight males. Peanuts were shown to be atheroprotective as part of a high-fat meal, potentially reducing the risk of coronary disease.
Research shows that CT scans paired with standard care lead to more accurate diagnoses of coronary artery disease, altering follow-up testing and treatments. This results in a lower incidence of heart attacks among patients receiving the test compared to those receiving usual care.
The report highlights key diagnostic challenges in women, including atypical symptoms and the need to understand sex-specific differences underlying CAD. It emphasizes the importance of genomic approaches to diagnosis and the potential benefits of these new advances for improving accuracy and avoiding unnecessary invasive procedures.
A 20-year follow-up study found that frequent sauna use can reduce the risk of cardiac death in men. Men who used saunas 4-7 times a week were 63% less likely to experience sudden cardiac death compared to those using them once a week. Longer sauna sessions also reduced cardiovascular risks.
A new study found that diabetic patients with even mild coronary artery disease are at a comparable risk of heart attacks and major adverse events to those with severe obstructive disease. Researchers used cardiac computed tomography angiography data from 14,000 patients to evaluate long-term prognostic value in diabetic patients.
A study of 68,765 STEMI patients found that 53% had non-IRA disease, significantly associated with increased 30-day mortality. The presence of non-IRA disease was consistent with findings from the KAMIR registry but not the Duke database.
A study of nearly 38,000 patients found that those diagnosed with nonobstructive coronary artery disease (CAD) had a significantly increased risk of heart attack or death one year after diagnosis. Patients with nonobstructive CAD had an associated risk of MI that was 2-to 4.5-fold greater than among those with no apparent CAD.
Researchers used coronary computed tomography angiography (CCTA) to detect high-risk coronary artery plaque and non-alcoholic fatty liver disease (NAFLD), a condition characterized by abnormal liver function. The study found that NAFLD is associated with high-risk plaque, even after adjusting for traditional risk factors.
Despite no detectable coronary artery disease, nearly three-quarters of patients experience severe or moderate symptoms before and after angiography. Symptoms persist in over seven out of ten cases. Validated questionnaires reveal higher anxiety levels, increased somatoform disorders, and hypochondria in these patients.
A new study by researchers at Intermountain Medical Center Heart Institute suggests that lifestyle choices, not just genetics, may contribute to the risk of heart attack. The study found that severe coronary artery disease can be inherited, but the presence of heart attacks in people with less severe disease was not clustered in families.
Researchers developed new methods to reduce imaging time in myocardial perfusion imaging (MPI) by up to 50%, making scans easier for patients. The methods also correct errors caused by patient movement, resulting in error-free MPI images.
A new study reveals that PET/MR imaging is highly effective in detecting coronary artery disease, outperforming traditional SPECT methods. The hybrid technique provides a comprehensive view of the heart, combining anatomical and functional information for more accurate diagnoses.
Researchers identified a gene expression profile associated with an increased risk of cardiovascular death in patients with coronary artery disease. The profile, based on a simple blood test, may help identify patients who could benefit from personalized treatment and counseling.
Researchers found an estimated 9 million people with diabetes and 5.6 million people with coronary artery disease are not receiving statins, highlighting a concerning trend driven by high cholesterol. Statin use is often associated with reduced cardiovascular risk, regardless of cholesterol levels.
A study published in Annals of Internal Medicine found that men with HIV have a greater risk and extent of coronary artery disease compared to uninfected men. Meanwhile, nearly one-third of patients fail to fill their first-time prescriptions, which may impact clinical outcomes.
A Johns Hopkins study reveals that long-term HIV infections increase the risk of plaque buildup in coronary arteries, regardless of other risk factors. The researchers found noncalcified and partly calcified plaques more prevalent in HIV-infected men, suggesting a higher risk of heart attacks.
People with celiac disease may have a near two-fold increased risk of coronary artery disease compared to the general population. Researchers found that systemic inflammation and autoimmune processes might influence cardiovascular disease development.
People who are married have lower rates of several cardiovascular diseases compared to those who are single, divorced, or widowed. Married individuals were found to be 5% less likely to have any vascular disease and had lower odds of other vascular conditions.
A large-scale survey of 3.5 million Americans found that married people have a significantly lower risk of heart disease than singles, divorced, or widowed individuals. The study also revealed age-related differences in cardiovascular disease risk among married couples.
Research shows that vitamin D deficiency is associated with higher prevalence and severity of coronary artery disease. Patients with low vitamin D levels are at a higher risk of developing severe heart disease, and the study suggests that vitamin D may be beneficial in preventing heart disease.
A new blood test detects specific genes activated in individuals with obstructive coronary artery disease (CAD), excluding diagnosis without imaging studies. This approach reduces healthcare costs and may improve patient outcomes by minimizing invasive tests.
A study evaluated the role of infliximab in treating Kawasaki disease, a condition that can lead to irreversible heart damage if not diagnosed or treated promptly. Infliximab treatment was found to be safe and effective in preventing coronary artery damage in children with Kawasaki disease.
Sanford-Burnham researchers identify THRIL molecule that regulates immune response and associates with Kawasaki disease severity. THRIL may also contribute to other inflammatory diseases like rheumatoid arthritis and inflammatory bowel disease.
Patients undergoing cardiac surgery have a substantially higher risk of depression if they are physically inactive, with 58% of those at-risk progressing to clinical depression. Inactive patients also experience double the risk of depressive symptoms before surgery and postoperatively.
Cardiovascular complications and hypoglycemia are common nonfatal complications in older adults with diabetes. The study found that patients with diabetes for a longer duration had higher rates of all outcomes, including mortality.
An international multicenter study found that men and women with mild coronary artery disease and similar cardiovascular risk profiles share similar prognoses. The study analyzed data from 27,725 individuals in six countries and revealed that nonobstructive coronary artery disease conferred a similar adverse risk of death or heart atta...
A new study by Johns Hopkins Medicine found that higher levels of physical fitness lower the risk of having heart attacks and increase survival in those with coronary artery disease. The study included over 9,800 adults with coronary artery disease and showed a 75% lower risk of dying from any cause among the fittest patients.
A new study by Johns Hopkins Medicine found that young and middle-aged women with type 2 diabetes are at a significantly increased risk of coronary artery disease, comparable to men's risk. The study analyzed data from over 10,000 participants and suggests distinct genetic and hormonal factors may contribute to the higher risk.
The ADVISE II trial found that iFR accurately classified 94.2% of coronary stenoses, with high positive and negative predictive values for hemodynamically severe stenosis detection. The study supports the use of iFR to simplify physiological guidance of percutaneous coronary intervention without adenosine administration.
A study published in JAMA found that coronary artery bypass graft (CABG) surgery provides slightly better health status and quality of life than procedures using drug-eluting stents for patients with diabetes and multiple arteries affected, but this difference disappears beyond 2 years.
A global analysis of Kawasaki disease cases found a seasonal occurrence shared by regions across the Northern hemisphere, with peak cases in winter months. The study suggests that large-scale wind currents may play a role in transmitting the suspected infectious agent.
A study published in JAMA Network found that aliskiren, a renin inhibitor, did not slow the progression of coronary artery disease in patients with prehypertension. The treatment had no significant impact on atheroma burden or regression of fatty deposits.
A retrospective study from Cleveland Clinic found that patients who underwent stenting of the carotid artery followed by open heart surgery had the best outcomes. The researchers compared three common treatment approaches and found that this combination had significantly lower risks of serious events after one year.
Coronary artery disease (CAD) disproportionately affects women, with unique risk factors including pregnancy and autoimmune diseases. Women are more likely to die from CAD than men in similar circumstances, especially at younger ages.
Researchers found a significant difference in cardiac catheterization rates between New York State and Ontario, with New York performing fewer procedures due to lower obstructive coronary artery disease (CAD) burdens. This selective approach improved diagnostic efficiency while reducing costs.
A new study found that DNA particles in the blood can serve as markers of disease and may help identify patients with severely narrowed coronary arteries. Higher levels of these particles were linked to high levels of coronary artery calcium deposits.
Researchers found that men with haplogroup I have lower numbers of copies of two important genes in macrophages, which may contribute to increased risk of coronary artery disease. The study used a sample of around 2,000 men from four European populations and aimed to decipher the genetic background behind the association.
Patients with low baseline diastolic blood pressure (DBP) had more subcortical brain atrophy progression. Those with declining DBP levels over time showed less brain atrophy progression compared to those with rising BP levels.
Researchers found that metabolic PET imaging detected coronary disease at an early stage, with a sensitivity of 96%, compared to 56% for MPI. This technique could potentially be used for initial CAD screening to help doctors better determine a patient's cardiac risk and manage care.
A recent study published in the Canadian Medical Association Journal found that people with job stress and an unhealthy lifestyle are at a higher risk of coronary artery disease. The study analyzed data from 7 cohort studies involving 102,128 participants and found that those with job strain had a 10-year incidence rate of 18.4 per 100...
A new study links type 1 diabetes to an increased risk of heart disease through the production of the inflammatory protein calprotectin, which fuels the buildup of artery-clogging plaque.
A large study found that high serum C-peptide levels are linked to an increased risk of death from all causes and cardiovascular disease. People with high C-peptide levels had a 1.8- to 3.2-fold increased risk compared to those with low levels.
A meta-analysis of published evidence found a link between male pattern baldness and an increased risk of coronary heart disease, especially on the crown of the head. Men with extensive vertex baldness were 44% more likely to develop coronary artery disease than those with a full head of hair.