Articles tagged with Coronary Artery Disease
A prospective study in the Canadian Journal of Cardiology found that dedicated women's heart centers can significantly improve clinical and psychological outcomes for women with myocardial ischemia. The study, which followed 154 patients, showed a significant decrease in chest pain frequency and improved quality of life after attending...
The study found that the probability of surviving cardiac arrest outside hospital has more than doubled in 30 years, from approximately 5% to 11%. The improvement is attributed to increased CPR training and better healthcare resources. However, ambulance delays and an increase in difficult-to-treat cases are hindering further progress.
Researchers developed a polygenic risk score to predict sudden cardiac death in coronary artery disease patients. The study found that patients with high genetic risk scores had a 77% increased risk of sudden cardiac death.
TCT 2022 will feature late-breaking clinical science presenting the safety and effectiveness of minimally invasive techniques, pharmaceuticals, technologies, and devices for treating or preventing cardiovascular disease. The event takes place September 16-19 in Boston at the Boston Convention and Exhibition Center.
A VA study found nearly identical genetic variations contributing to coronary heart disease risk across major racial and ethnic backgrounds. The findings suggest that other factors like access to healthcare contribute to higher heart disease rates in certain populations.
The Women's Preventive Services Initiative issues guidelines for preventing obesity in midlife women, recommending counseling on healthy eating and physical activity. The guideline aims to mitigate concerns about weight stigma by normalizing counseling among all midlife women, regardless of BMI status.
A new analysis from the Family Heart Foundation shows that only 31.3% of individuals with familial hypercholesterolemia (FH) in its database had been diagnosed as of June 2020. This represents a significant increase since 2016, but highlights the ongoing challenge of diagnosing and managing the condition.
Researchers have created a new DNA atlas that provides insights into how genes in specific cells contribute to coronary artery disease. The atlas identifies over 200 independent genetic markers associated with disease risk, offering a potential roadmap for interpreting non-coding variants.
The Heart and Lung Research Institute (HLRI) at the University of Cambridge will bring together over 380 researchers and clinicians to tackle cardiovascular and respiratory diseases. The institute aims to deliver high-impact research to drive breakthroughs in prevention, early diagnosis, and treatment of these diseases, which represent...
A long-term study of 3,926 adults with CKD found that higher levels of physical activity reduced the risk of atherosclerotic events, new-onset heart failure, and death. The association was strongest for incident peripheral arterial disease and reinforces current guideline recommendations.
A new study published in Behavior Genetics found that natural selection favors characteristics associated with lower earnings and poorer education, such as having more children. The research, led by UEA, analyzed data from over 300,000 people in the UK and suggests that this may be contributing to increasing income inequality.
Researchers developed an AI method to automatically detect plaque erosion in heart arteries using OCT images. The new technique uses neural networks and post-processing algorithms to predict regions of possible plaque erosion and refine the initial prediction based on clinically interpretable features.
A novel study published in the Canadian Journal of Cardiology demonstrates that Nordic walking provides greater long-term improvements in functional capacity compared to high-intensity interval training and moderate-to-vigorous intensity continuous training. Nordic walking engages core, upper, and lower body muscles, resulting in a sig...
Researchers found a potential association between COVID-19 vaccines and an increased risk of coagulation disorders and coronary artery disease events. The study analyzed data from Norway, Finland, and Denmark to investigate this connection.
A study using PET imaging found that severe obstructive sleep apnea is associated with abnormal heart blood flow reserve, increasing the risk of heart disease. The findings suggest that cardiac PET imaging can identify high-risk OSA patients.
A long-term study found that cigarette smoking significantly increases the risk of developing both reduced ejection fraction and preserved ejection fraction heart failure. Former smokers retained a higher risk of heart failure for decades after quitting, with the risk decreasing only after 30 years without smoking.
Researchers from NTU and NUS found a link between NAFLD and blood vessel damage, leading to increased risks of cardiovascular diseases. High levels of chemokines attract immune cells into blood vessels, causing inflammation and damage.
A new analysis of the PROGRESS-CTO registry shows a significant increase in successful CTO PCI procedures, with higher efficiency and lower risk of complications. The findings demonstrate improved operator training and real-world experience leading to better patient outcomes.
A nationwide study reveals lower rates of cardiac catheterization and revascularization among non-Hispanic Black patients with a history of cocaine use compared to white patients. The findings suggest implicit bias in treatment, emphasizing the need for health equity.
A new study reveals that allergic asthma is a significant risk factor for human cardiovascular diseases, with certain medications affecting heart health. Researchers found that inflammatory cells play a crucial role in both conditions and that targeting them may lead to better treatment options.
Researchers at UC San Diego School of Medicine found that COVID-19, MIS-C and Kawasaki disease share similar underlying molecular patterns. The study reveals that MIS-C is a more severe version of the immune response than KD, with potential implications for improved disease diagnosis and treatment.
Scientists use advanced measurement methods to study carotid artery stenosis, discovering significant gaps between their findings and clinical methods. They propose improvements for surgical treatment technology and future medical devices.
A new study from Norway found that COPD patients have a higher degree of coronary artery calcification and narrower coronary arteries. The researchers discovered an increased risk of coronary disease in COPD patients, independent of disease severity, emphasizing the importance of early detection.
A study by Kobe University researchers has illuminated the characteristics of Myeloid immune cells in coronary plaque, a major contributor to acute coronary syndrome. The findings suggest that macrophages and monocytes accumulate in the plaques of patients with acute coronary syndrome, leading to increased inflammation.
A new study published in Radiology: Cardiothoracic Imaging found that aspirin therapy did not reduce major cardiovascular events in patients with non-obstructive coronary artery disease. Statin use, however, was associated with a significant reduction in cardiovascular events.
Researchers found smokers have significantly lower A1AT levels, which may reduce cardiac tissue protection during a heart attack. No difference was detected in hypertensive and non-hypertensive individuals.
A prospective study found that the 3-T Dixon gradient-recalled echo (GRE) sequence performed better than the current standard of 1.5-T SSFP for unenhanced coronary MRA, particularly in distal and branch segments. The technique demonstrated higher image quality, visible segments, sensitivity, and specificity for significant stenoses.
A new smartphone app developed by Scripps Research calculates genetic risk for coronary artery disease and finds that users at high risk are more likely to start using statins or other cholesterol-lowering therapies. The app, called MyGeneRank, uses genetic data from 23andMe and outputs a CAD risk score.
Researchers at the University of Virginia Health System have identified a potential way to treat obesity and type 2 diabetes in women by targeting a specific gene called KLF14. Increasing KLF14 abundance in fat cells may help alleviate metabolic abnormalities, including slower metabolic rates and less efficient triglyceride management.
A comprehensive analysis suggests that cardiac computed tomography (CT) provides a safe alternative to cardiac catheterization for patients with stable chest pain and suspected CAD. The trial confirms CT's diagnostic accuracy, while also showing lower procedure-related complications.
The American Roentgen Ray Society recognizes Drs. Nguyen, Beheshtian, Harfouch, and Hashiba for their outstanding research and education contributions to the field of radiology. The awards honor the candidates' scientific merit and potential impact on imaging and allied sciences research.
A new study has identified the critical genes most likely to cause coronary heart disease and trigger heart attacks. The research provides a prioritized list of 162 genes, which will enable more accurate genetic testing and targeted therapies for patients at risk of coronary heart disease.
A small study found statistically significant improvements in various symptoms, including fatigue and chest discomfort, after EECP therapy in long COVID patients. Researchers believe this is the most plausible explanation for the benefits derived from EECP and its link to long COVID.
The annual conference will cover important themes such as decision-making in coronary revascularization, specific treatment of complex lesion subsets, and the use of adjunctive tools. CTO Plus 2022 will feature 12 live case transmissions performed by world-class faculty members.
A new study from USF Health reveals that activated protein C may help improve aging patients' tolerance to reperfusion injury, a potentially adverse effect of treatment for ischemic heart disease. The researchers suggest that drugs derived from APC may limit ischemia and reperfusion-induced heart damage.
A new study published in Clinical Nutrition found that drinking less than the UK's recommended 14 units of alcohol per week increases the risk of cardiovascular events. Moderate alcohol consumption is associated with a 23% increased risk of suffering a cardiovascular event for every additional 1.5 pints of beer consumed.
A study suggests that nearly 60 percent of the risk associated with coronary artery disease may be explained by changes in hundreds of genes working together in networks across several organs. Fat processing hormones may play a central role in coordinating this activity.
A new PET/CT artificial intelligence model has been developed to predict the risk of future heart attacks with improved accuracy. By combining information from PET and CT angiography, the model provides a more robust prediction of heart attack risk than clinical data alone.
A new issue of the CVIA journal has been published, featuring research on the clinical significance of angiographically detectable neovascularity in patients with cardiac myxoma. Studies found that ADN was present in 42.4% of patients and was associated with higher levels of eosinophils and low-density lipoprotein cholesterol.
A Mayo Clinic study reveals that cardiovascular risks, including coronary artery disease and diabetes, have a stronger association with memory and thinking skills decline in middle-aged women. The research found that women with these conditions experience an annual decline in global cognition more than two times greater than men.
The new guideline recommends a patient-centric approach to managing patients with coronary artery disease, incorporating clinical indications and multidisciplinary team decision-making. The guideline aims to improve quality of care and reduce disparities in treatment, particularly among women and underrepresented racial or ethnic groups.
Women with breast implants after mastectomy are at high risk of developing cardiovascular disease due to chemotherapy and radiation. Inaccuracies in cardiac imaging studies, such as echocardiography and nuclear tests, have been reported in some cases.
A new study from the University of Eastern Finland found that patients with type 2 diabetes often do not receive adequate cholesterol-lowering treatment, despite guidelines recommending statin prescriptions for elevated LDL-C levels. Women tend to have higher average LDL-C levels and receive less statin treatment than men.
The global red and processed meat trade has risen exponentially, leading to a sharp increase in diet-related illnesses, particularly bowel cancer, diabetes, and coronary artery heart disease. Health policies should be integrated with agricultural and trade policies to address this issue.
A new risk score developed by Mount Sinai researchers can help predict possible contrast-associated acute kidney injury among patients undergoing PCI. The 'Mehran-2 CA-AKI Risk Score' enhances management of high-risk patients before, during, and after the procedure.
A new trial shows that the novel surgical device venous external support (VEST) may improve outcomes of coronary bypass grafting using leg veins by preventing intimal hyperplasia, a key factor in vein graft failure.
A new study published in The New England Journal of Medicine found that percutaneous coronary intervention (PCI) guided by fractional flow reserve (FFR) did not meet noninferiority for one-year outcomes compared to bypass surgery. However, FFR-guided PCI performed favorably in patients with low SYNTAX scores and less complex disease.
A new study found that QFR-guided PCI resulted in lower one-year rates of heart attack and a lesser chance of needing additional PCI, with a 35% reduction in mortality. The technology helped eliminate unnecessary stents and identified more obstructive lesions.
A new canine mutant model mimics human cerebrovascular disease by exhibiting severe arteriosclerosis, thrombosis, and stroke. The ApoE knockout dogs show extensive and severe arteriosclerosis plaques and arterial stenosis, consistent with human cerebral arteries and coronary arteries.
The ACC Middle East 2021 conference will showcase the latest evidence-based strategies for improving heart health in the Middle East. The event features presentations from renowned experts on the most impactful clinical trials and contemporary best practices in treating cardiovascular disease.
Research suggests that people sensitive to stress hormones are at greater risk of developing cardiovascular disease, with markers indicating increased risk of stroke and heart attack. A novel proteomic signature may help identify these individuals and inform stress management strategies.
A new study finds that left-sided breast cancer radiation therapy increases the risk of coronary artery disease in younger survivors, with a significant increase in risk seen at 10.5% for those who received left-sided radiation therapy compared to 5.8% for right-sided.
Researchers develop novel models to investigate the impact of drug-eluting stents on arterial tissue permeability and blood flow. The study identifies key factors contributing to restenosis near stent edges, highlighting potential avenues for design improvements.
The MASTER DAPT trial found that one month of dual antiplatelet therapy preserves ischemic benefits and reduces bleeding risk in high bleeding risk patients. Abbreviated DAPT was noninferior to standard DAPT in terms of net adverse clinical events, but superior in reducing major or clinically relevant nonmajor bleeding.
A new study found that 44% of micro-arteries from patients had abnormal myogenic tone, associated with excessive caldesmon presence and poor cell alignment. This abnormality affects blood supply within the heart and other organs, impacting quality of life and life expectancy.
Researchers developed a new imaging technique that uses light and sound to detect plaques in arteries, potentially preventing strokes and heart attacks. The technique uses nanoparticles that absorb light and emit sound waves, allowing doctors to visualize the plaques in a non-invasive way.
A study found a strong association between pre- and post-transplant cardio-cerebrovascular diseases, with an estimated hazard ratio of 12.50. Pre-transplant CCVD was independently associated with high non-relapse mortality and inferior survival in patients undergoing hematopoietic cell transplant.
The study used single cell technology to map epigenetic changes in different cells involved in coronary artery disease, revealing that genetic risk variants are particularly enriched in endothelial and smooth muscle cells. This research provides a new understanding of the role of these cells in transmitting susceptibility to the disease.
A study of 805,992 Japanese individuals found that systolic blood pressure (SBP) above 120 mmHg increases the rate of cardiovascular disease. SBP levels were also associated with an increased risk of coronary artery disease and cerebrovascular disease, even in individuals with normal glucose status.
A global health problem has been identified as microvascular angina, a disease affecting the smallest heart blood vessels. The study found that patients with MVA experience chest pains similar to those of a heart attack, yet are often misdiagnosed due to the lack of definitive diagnostic criteria.