Articles tagged with Coronary Artery Disease
A new approach to combine CT and MRI data in one 3D image helps solve uncertain findings in coronary artery disease diagnosis. The technique correlates specific stenoses with possible cardiac scar tissue and ischemia, guiding revascularization procedures.
The article proposes algorithms for evaluating patients with suspected or confirmed COVID-19 and signs of acute heart attack, guiding triage and treatment. Mayo Clinic cardiologists and radiologists emphasize the importance of immediate and appropriate treatment to minimize risks for both patients and medical staff.
The journal CVIA has published a new issue featuring important research papers from leading cardiologists worldwide. The International Brugada Electrocardiographic Indices Registry invites new members to contribute to evaluating the disease life course, risk factors, and prognosis in Brugada patients.
Low serum vaspin levels are associated with coronary artery stenosis, while plasma concentration reflects possible endothelial dysfunction in CAD patients and correlates with disease severity. Vaspin also associates with metabolic syndrome and obesity parameters.
Women with coronary artery disease experience more chest pain due to plaque build-up, but have less extensive disease compared to men. The study highlights the need for more research and clinicians to adopt a dual focus to prevent cardiovascular events and improve patients' quality of life.
The study evaluated nationwide data from 2003 to 2016, assessing changes in the risk profiles and number of patients undergoing revascularization. It found an increase in elderly patients, racial minorities, and those with lower income, as well as a decrease in the use of coronary artery bypass grafting.
A new pilot study found that a 90-second magnetocardiography scan using CardioFlux Magnetocardiograph can help rule out coronary artery disease in patients presenting with chest pain. The test showed competitive results relative to stress testing and coronary angiography, with high specificity and negative predictive value.
Researchers at Intermountain Medical Center found that omega-3 fatty acids do not increase the risk of prostate cancer, contrary to earlier studies. High levels of omega-3s also showed a lower risk of adverse cardiovascular events and death in patients with severe coronary artery disease.
The World Heart Federation's new roadmap outlines a vision for ideal CVD prevention pathways, highlighting gaps in care for people living with diabetes. Developed in partnership with the IDF, it presents an integrated approach to patient care and provides implementation tools for national initiatives.
Research presented at ESC Congress 2019 found that genetic high cholesterol is underdiagnosed and undertreated, with a prevalence of 3.6-4.5 million individuals in Europe. Screening for the condition could identify patients and family members affected by heterozygous familial hypercholesterolaemia, allowing for lifestyle changes and tr...
A new study found that left-ventricular hypertrophy is a stronger predictor of heart failure than coronary artery calcium score. The study analyzed data from 6,814 men and women with no known heart disease and found that LV hypertrophy increased the risk of CHD events by 4.3 times.
A new study found that cigarette smoking significantly increases the risk of peripheral artery disease, which can persist for up to 30 years after quitting. Compared to never-smokers, smokers had a fourfold increased risk of developing peripheral artery disease.
A multicenter study found that deep learning analysis of single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) improved the diagnosis of obstructive coronary artery disease. The new method showed increased sensitivity and accuracy compared to traditional methods, leading to better patient outcomes.
A recent study published in The Annals of Thoracic Surgery found that coronary artery bypass grafting (CABG) surgery is associated with lower mortality rates and reduced hospital readmission compared to percutaneous coronary intervention (PCI). The research analyzed data from two major clinical outcomes registries and identified patien...
Researchers found a significant reduction in strokes and heart attacks with low-dose blood thinner use in patients with worsening heart failure or coronary artery disease. The study, published in JAMA Cardiology, suggests that this strategy may improve outcomes for patients at risk of subsequent issues.
Research from the Cardiovascular Research Foundation will present latest data on PCI, imaging technologies, and TAVR at ACC.19. The study found that treatment with angiotensin-converting enzyme inhibitors or receptor blockers affects revascularization after percutaneous coronary intervention.
Adults who vape are significantly more likely to have a heart attack, coronary artery disease, and depression compared to non-users. The study found that e-cigarette users were 56% more likely to have a heart attack and 30% more likely to suffer a stroke.
A study found that radiologists only reported coronary artery calcium (CAC) on CT scans about half the time, despite its importance as a marker of heart health. This underreporting could lead to missed opportunities to identify and treat patients at high risk for heart problems, researchers say.
A recent study found that patients in Medicare Advantage plans are more likely to receive guideline-recommended therapy for coronary artery disease, compared to those in traditional fee-for-service Medicare. However, there were no significant differences in blood pressure and cholesterol control between the two groups.
A study from Duke Health researchers reveals that MRI cardiac stress testing can predict mortality and diagnose coronary artery disease more effectively than existing methods. The non-invasive technology has potential as an alternative to stress echocardiograms, catheterizations, and nuclear exams.
A team of UA researchers discovered a previously unknown genetic effect that can raise or reduce the risk of coronary artery disease or ischemic stroke. People with the beneficial version of the genetic factor have less inflammatory cells lining their blood vessels, making them more resistant to building up plaque.
A Cleveland Clinic genetic analysis found that excess fat itself is harmful to cardiovascular health, increasing the odds of Type 2 diabetes by 67% and coronary artery disease by 20%. The study used genetic data from over 880,000 participants, suggesting a significant association between obesity and these conditions.
The OAC-ALONE study found that oral anticoagulation (OAC) alone did not provide non-inferiority to combined OAC and antiplatelet therapy in patients with atrial fibrillation and stable coronary artery disease beyond one year after stent implantation. The study also found higher rates of major bleeding with OAC alone.
A new AI model has been developed that can predict the risk of death in patients with heart disease more accurately than medical experts. The model was trained on electronic health data from over 80,000 patients and identified new variables that doctors hadn't considered.
A study found that febuxostat significantly reduced the rate of primary endpoint events, including cerebral and cardiovascular disease. Lowering serum uric acid levels also decreased renal impairment and related complications.
A new study found that combining oral anticoagulants with antiplatelets worsened outcomes in patients with newly diagnosed atrial fibrillation, especially those without coronary artery disease or peripheral artery disease. This challenges the use of combined therapy in these patients.
A recent study published by the European Society of Cardiology found that sleeping six to eight hours a night is most beneficial for heart health. The research, which analyzed data from over one million adults, suggests that both short and long sleepers have an increased risk of developing coronary artery disease or stroke.
The new guidelines recommend open heart surgery for patients with complex coronary artery disease, as it provides better long-term survival and outcomes compared to stent placement. In contrast, patients with simpler disease can benefit from both surgical bypass and PCI, with complete revascularization being the preferred option.
A new genome analysis method predicts risk for coronary artery disease, breast cancer, and type 2 diabetes based on genetic variants. Up to 25 million people in the US may be at triple the normal risk for coronary artery disease, highlighting the potential for early interventions.
A study published in Radiology found that cardiac hybrid imaging, combining CT and nuclear stress testing, is an excellent long-term predictor of adverse cardiac events. The imaging approach helps identify stenosis and perfusion, providing critical information for treatment decisions.
Researchers at Florida State University emphasize the importance of early depression diagnosis in patients with coronary artery disease. Studies have shown that individuals with both CAD and depression experience significantly poorer health outcomes, including a two-fold higher risk of mortality. The article provides criteria for major...
The study reveals a tendency for duplication in the 9p21.3 sequence associated with coronary artery disease, which may affect predisposition to CAD. Sequence analysis shows varied repeats with 10-15 SNPs between each other and 82 SNPs between the human genome sequence.
Researchers found that hospitalized patients with coronary artery disease who developed low blood glucose levels during their stay had higher mortality rates, longer hospital stays, and increased healthcare costs. Frequent glucose monitoring could potentially save lives and decrease hospital length of stay and healthcare expenses.
Researchers found that imaging technologies more precisely predict who's at risk for heart attacks, allowing for timely prevention. The study used PET/CT imaging to measure coronary artery calcium, revealing existing disease and identifying patients at high risk.
A review published in the Journal of the American College of Cardiology suggests that environmental noise, including traffic noise, may contribute to the development of heart disease. The study proposes that noise induces a stress response, leading to vascular damage and increased risk of hypertension and diabetes.
A new multi-gene test predicts a high risk for early-onset heart disease in 1 out of 53 individuals, surpassing the prevalence of a rare genetic defect. The study suggests that combining polygenic screening with current testing could identify five-fold more cases with a genetic explanation.
A Mayo Clinic study reveals that hysterectomy alone is associated with a significantly increased risk of cardiovascular diseases and metabolic conditions. Women under 35 had a high risk of congestive heart failure and coronary artery disease.
A study of 6,051 patients with coronary artery disease found that being unmarried was associated with a 24% higher risk of death from any cause. Unmarried individuals were also at a higher risk of cardiovascular death/heart attack, with a 52% increased risk compared to married patients.
A meta-analysis of trials involving nearly 5,000 patients found no differences in mortality between percutaneous coronary intervention and coronary artery bypass grafting. Percutaneous coronary intervention is less burdensome on patients, enabling rapid return to work without long-term hospitalization.
A blood-based precision medicine test incorporating age, sex, and gene expression score (ASGES) helped evaluate older outpatients with symptoms of obstructive coronary artery disease. The study found higher incidence of major adverse cardiovascular events in those with high ASGES scores compared to low ASGES scores
A study published by the European Society of Cardiology found that male-pattern baldness and premature greying are associated with a higher risk of coronary artery disease in young men. Obesity was also linked to an increased risk, but not to the same extent as these two factors.
A study published in the American Journal of Pathology found that higher levels of the protein CXCL5 are associated with clearer heart arteries and lower risk of coronary artery disease. Researchers believe that mimicking or increasing CXCL5 production could lead to new prevention and treatment strategies for CAD.
Researchers found that individuals with A, B, and AB blood types have an elevated risk of heart attacks during times of significant air pollution compared to those with O blood type. The study links increased risk of heart attack associated with small particulate pollution to increased risk for people with coronary artery disease.
A study of over 60,000 patients with known heart disease found that follow-up LDL cholesterol tests significantly reduce the risk of reoccurring heart attacks and strokes. Patients who didn't receive these tests were more likely to experience major adverse outcomes.
Research suggests anabolic androgenic steroid use may be associated with early coronary artery disease in healthy young individuals. The study found that steroid users had atherosclerosis, reduced HDL levels, and impaired HDL function.
Patients with left main coronary artery disease (LMCAD) who underwent percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG) showed similar quality of life improvements at three years. PCI demonstrated a greater early benefit, with improved health status measures that were sustained over time.
The ESC Focused Update provides recommendations for dual antiplatelet therapy (DAPT) in patients with coronary artery disease. DAPT reduces the risk of acute to very late stent thrombosis, but the optimal duration is uncertain. The Task Force recommends a personalized approach based on ischaemic versus bleeding risks.
The ESC Guidelines provide comprehensive recommendations for the diagnosis and treatment of peripheral arterial diseases, affecting over 40 million Europeans. Key findings include revised guidelines for revascularization of asymptomatic carotid stenosis and a strong recommendation against systematic revascularisation of renal stenosis.
A multicenter study found a significant association between higher income and increased risk of coronary artery disease and multivessel disease among patients undergoing coronary angiography. Poor lifestyle practices, including physical inactivity, unhealthy diet, and tobacco use, contribute to this finding.
A new study finds that depression in heart patients significantly increases the risk of death, with depressed heart patients having twice the risk as non-depressed heart patients. The study emphasizes the importance of continued screening for depression in all heart disease patients.
A genetic variant at chromosome 6p24 is associated with five vascular diseases, including coronary artery disease and hypertension. The variant enhances the activity of endothelin-1 gene, promoting vasoconstriction and hardening of arteries.
A genetic predisposition to higher blood calcium levels is associated with an increased risk of coronary artery disease and heart attack. The study used mendelian randomization to examine the association between serum calcium levels and CAD, finding a link between the two.
A study published in The Open Cardiovascular Medicine Journal found that higher income is associated with a higher risk of significant coronary artery disease and multivessel disease in patients undergoing coronary angiography. Poor lifestyle practices and high stress levels are thought to contribute to this association.
Researchers at Linkoping University discovered that lutein can suppress long-term inflammation in patients with coronary artery disease. The study found that higher levels of lutein were associated with lower levels of inflammatory markers and reduced inflammatory activity in immune cells.
Researchers found that new opioid use among older adults with COPD is associated with a higher risk of coronary artery disease-related death. The study suggests that opioids may have negative effects on the heart, including lower blood oxygen levels and increased inflammatory factors.
A genetic study suggests that human genes for coronary artery disease contribute to greater numbers of children, providing an evolutionary trade-off between early-life reproductive benefits and later-life disease costs. The study uses genome-wide scans and lifetime reproductive data to identify genetic variation linked to the disease.
Researchers have found that genes for coronary heart disease (CAD) also influence reproduction, suggesting a trade-off between heart disease and fertility. The study, published in PLOS Genetics, reveals CAD genes have been positively selected for through evolution, improving human reproduction.
Research reveals a defective immune cell's sweet tooth predisposes people to shingles, exacerbating heart disease. The connection shows how the same mechanism disabling immune response to viral infections also affects heart conditions.
Researchers have discovered 15 new genetic risk factors for coronary artery disease, linking them to blood vessel cell functions. The findings aim to improve understanding of the disease and inform the development of new therapies.
Chronic anabolic steroid use can lead to reduced heart function, including impaired pumping capacity and increased blood pressure. The study found strong associations between lifetime duration of illicit anabolic steroid use and plaque build-up in coronary arteries, highlighting the critical need for clinicians to monitor this population.