Articles tagged with Coronary Artery Disease
A meta-analysis found that adding revascularization to medical therapy reduces cardiovascular death by 21% in patients with stable ischemic heart disease. The benefit increases over time, with a greater impact on survival for those with extensive disease.
A study found that people living with HIV have a two to three times higher noncalcified coronary plaque burden than non-HIV healthy volunteers. Researchers emphasize the importance of adopting a heart-healthy lifestyle for those with HIV.
Developed and validated clinical prediction models estimate the probability of patients having coronary artery disease (CAD) using a nomogram. The nomogram improves accuracy in Chinese populations by identifying individualized risk factors.
Men with stable coronary artery disease who take Viagra live longer and have lower risk of new heart attack compared to those treated with alprostadil. The study's findings suggest a dose-dependent reduction in cardiovascular events.
A new study reveals that over one third of genetic variants associated with coronary artery disease regulate liver-specific genes involved in cholesterol metabolism. Researchers pinpoint the causal single nucleotide polymorphisms and target genes mediating the risk, expanding our understanding of the disease's mechanisms.
A study published in Radiology found that cocaine use significantly affects the progression of coronary artery disease, while HIV infection has a more profound effect on younger individuals. Radiomics analysis revealed distinctive contributions of different risk factors to changes in plaque over time.
Researchers at UVA Health System identified a gene variant MIA3 that produces a protein promoting smooth muscle cell proliferation, leading to thicker, stable protective caps on blood vessel plaques. This discovery could help prevent heart attacks by stabilizing plaque lesions and reducing the risk of coronary artery disease.
A new screening questionnaire can predict individuals at high risk of coronary artery disease, according to a Swedish study. The questionnaire uses data easily measured at home and is successfully imaged using CCTA images to examine patients' arteries for the presence of plaque.
Women with premature menopause are at higher risk of developing coronary artery disease due to the presence of clonal hematopoiesis in their blood cells. The study found a 36% increased likelihood of clonal hematopoiesis and a 48% higher risk of coronary artery disease among women with premature menopause.
A study published in Nature Genetics developed a more accurate predictor of coronary artery disease based on genetic factors by comparing genome-wide association analysis across different ancestries. The researchers identified 48 genetic loci associated with the disease, including eight previously unknown variants.
Cases and deaths among younger cohorts are more prevalent in India than in high-income countries. The study found that cases and deaths were concentrated in children ages 0-14 years, adults older than 65 years, and had higher comorbidity rates than US cases.
The LoDoCo2 trial found that low-dose colchicine significantly reduced the risk of major cardiovascular events by almost one-third in patients with chronic coronary disease. The study also showed that colchicine was well-tolerated over the long-term, with no significant adverse effects.
Researchers used facial photos to detect coronary artery disease using a deep learning algorithm, achieving high sensitivity and specificity rates. The study shows promise for developing a self-reported application to assess heart disease risk in advance of visiting a clinic.
Among patients with peripheral artery disease (PAD) and coronary artery disease, limited use of recommended medications was observed. Despite similar treatment needs, Hispanics of Mexican background reported the lowest usage of cardiovascular medications, highlighting the need for targeted interventions.
Hospitalized patients with heart failure experience increasing comorbidity burden over time, particularly women with HFpEF. The study suggests a shift towards multi-morbidity heart failure, emphasizing the importance of managing multiple conditions in guiding patient care.
A combined analysis of six studies found that consuming chocolate more than once a week was associated with an 8% decreased risk of coronary artery disease. The researchers attributed the potential benefit to flavonoids and other heart-healthy nutrients in chocolate.
A large-scale survey found that meditation was associated with reduced rates of high cholesterol, high blood pressure, diabetes, stroke, and coronary artery disease. The study controlled for other factors connected to cardiovascular risk and still showed a significant effect of meditation on cardiovascular health.
Researchers at Massachusetts General Hospital developed an algorithm to track patients' medical records over time in EHRs to predict disease likelihood. The strategy connects information on medications and diagnoses, revealing accurate disease markers that can be interpreted by clinicians.
Researchers found that genetic risk scores can identify at-risk patients who are not presently identified through standard clinical evaluations. The study, published in the Journal of the American College of Cardiology, found that individuals with high PRS were more likely to develop coronary artery disease and should be recommended fo...
Researchers found that patients with peripheral artery disease or stroke were less likely than those with coronary artery disease to receive recommended treatments to prevent heart attack. Lifestyle changes and medication, including statins and aspirin, are crucial for all three types of atherosclerotic cardiovascular disease.
A new study has shown that patients with intermediate left main coronary artery disease are at a higher risk of cardiovascular events compared to those without the condition. The ISCHEMIA trial sub study found no significant difference in outcomes between invasive and conservative strategies for these patients.
The Society for Cardiovascular Angiography and Interventions (SCAI) has released a position statement on optimal percutaneous interventional therapy for complex coronary artery disease. The guidelines address the challenges of treating patients with advanced age, frailty, comorbidities, and compromised hemodynamic status.
A study published by The BMJ found that childhood body size is associated with an increased risk of coronary artery disease and type 2 diabetes in later life. However, a larger early life body size may help protect women against breast cancer. The study suggests that maintaining a normal body mass index (BMI) in adulthood can reduce th...
Researchers found a significant increase in premature coronary artery disease deaths among rural women under 65, while also noting that people living in rural areas have lower survival rates for heart failure. This disparity highlights the need for targeted public health efforts to improve cardiovascular health in rural communities.
A new approach to combine CT and MRI data in one 3D image helps solve uncertain findings in coronary artery disease diagnosis. The technique correlates specific stenoses with possible cardiac scar tissue and ischemia, guiding revascularization procedures.
The article proposes algorithms for evaluating patients with suspected or confirmed COVID-19 and signs of acute heart attack, guiding triage and treatment. Mayo Clinic cardiologists and radiologists emphasize the importance of immediate and appropriate treatment to minimize risks for both patients and medical staff.
The journal CVIA has published a new issue featuring important research papers from leading cardiologists worldwide. The International Brugada Electrocardiographic Indices Registry invites new members to contribute to evaluating the disease life course, risk factors, and prognosis in Brugada patients.
Low serum vaspin levels are associated with coronary artery stenosis, while plasma concentration reflects possible endothelial dysfunction in CAD patients and correlates with disease severity. Vaspin also associates with metabolic syndrome and obesity parameters.
Women with coronary artery disease experience more chest pain due to plaque build-up, but have less extensive disease compared to men. The study highlights the need for more research and clinicians to adopt a dual focus to prevent cardiovascular events and improve patients' quality of life.
The study evaluated nationwide data from 2003 to 2016, assessing changes in the risk profiles and number of patients undergoing revascularization. It found an increase in elderly patients, racial minorities, and those with lower income, as well as a decrease in the use of coronary artery bypass grafting.
A new pilot study found that a 90-second magnetocardiography scan using CardioFlux Magnetocardiograph can help rule out coronary artery disease in patients presenting with chest pain. The test showed competitive results relative to stress testing and coronary angiography, with high specificity and negative predictive value.
Researchers at Intermountain Medical Center found that omega-3 fatty acids do not increase the risk of prostate cancer, contrary to earlier studies. High levels of omega-3s also showed a lower risk of adverse cardiovascular events and death in patients with severe coronary artery disease.
The World Heart Federation's new roadmap outlines a vision for ideal CVD prevention pathways, highlighting gaps in care for people living with diabetes. Developed in partnership with the IDF, it presents an integrated approach to patient care and provides implementation tools for national initiatives.
Research presented at ESC Congress 2019 found that genetic high cholesterol is underdiagnosed and undertreated, with a prevalence of 3.6-4.5 million individuals in Europe. Screening for the condition could identify patients and family members affected by heterozygous familial hypercholesterolaemia, allowing for lifestyle changes and tr...
A new study found that left-ventricular hypertrophy is a stronger predictor of heart failure than coronary artery calcium score. The study analyzed data from 6,814 men and women with no known heart disease and found that LV hypertrophy increased the risk of CHD events by 4.3 times.
A new study found that cigarette smoking significantly increases the risk of peripheral artery disease, which can persist for up to 30 years after quitting. Compared to never-smokers, smokers had a fourfold increased risk of developing peripheral artery disease.
A multicenter study found that deep learning analysis of single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) improved the diagnosis of obstructive coronary artery disease. The new method showed increased sensitivity and accuracy compared to traditional methods, leading to better patient outcomes.
A recent study published in The Annals of Thoracic Surgery found that coronary artery bypass grafting (CABG) surgery is associated with lower mortality rates and reduced hospital readmission compared to percutaneous coronary intervention (PCI). The research analyzed data from two major clinical outcomes registries and identified patien...
Researchers found a significant reduction in strokes and heart attacks with low-dose blood thinner use in patients with worsening heart failure or coronary artery disease. The study, published in JAMA Cardiology, suggests that this strategy may improve outcomes for patients at risk of subsequent issues.
Research from the Cardiovascular Research Foundation will present latest data on PCI, imaging technologies, and TAVR at ACC.19. The study found that treatment with angiotensin-converting enzyme inhibitors or receptor blockers affects revascularization after percutaneous coronary intervention.
Adults who vape are significantly more likely to have a heart attack, coronary artery disease, and depression compared to non-users. The study found that e-cigarette users were 56% more likely to have a heart attack and 30% more likely to suffer a stroke.
A study found that radiologists only reported coronary artery calcium (CAC) on CT scans about half the time, despite its importance as a marker of heart health. This underreporting could lead to missed opportunities to identify and treat patients at high risk for heart problems, researchers say.
A recent study found that patients in Medicare Advantage plans are more likely to receive guideline-recommended therapy for coronary artery disease, compared to those in traditional fee-for-service Medicare. However, there were no significant differences in blood pressure and cholesterol control between the two groups.
A study from Duke Health researchers reveals that MRI cardiac stress testing can predict mortality and diagnose coronary artery disease more effectively than existing methods. The non-invasive technology has potential as an alternative to stress echocardiograms, catheterizations, and nuclear exams.
A team of UA researchers discovered a previously unknown genetic effect that can raise or reduce the risk of coronary artery disease or ischemic stroke. People with the beneficial version of the genetic factor have less inflammatory cells lining their blood vessels, making them more resistant to building up plaque.
A Cleveland Clinic genetic analysis found that excess fat itself is harmful to cardiovascular health, increasing the odds of Type 2 diabetes by 67% and coronary artery disease by 20%. The study used genetic data from over 880,000 participants, suggesting a significant association between obesity and these conditions.
The OAC-ALONE study found that oral anticoagulation (OAC) alone did not provide non-inferiority to combined OAC and antiplatelet therapy in patients with atrial fibrillation and stable coronary artery disease beyond one year after stent implantation. The study also found higher rates of major bleeding with OAC alone.
A new AI model has been developed that can predict the risk of death in patients with heart disease more accurately than medical experts. The model was trained on electronic health data from over 80,000 patients and identified new variables that doctors hadn't considered.
A new study found that combining oral anticoagulants with antiplatelets worsened outcomes in patients with newly diagnosed atrial fibrillation, especially those without coronary artery disease or peripheral artery disease. This challenges the use of combined therapy in these patients.
A study found that febuxostat significantly reduced the rate of primary endpoint events, including cerebral and cardiovascular disease. Lowering serum uric acid levels also decreased renal impairment and related complications.
A recent study published by the European Society of Cardiology found that sleeping six to eight hours a night is most beneficial for heart health. The research, which analyzed data from over one million adults, suggests that both short and long sleepers have an increased risk of developing coronary artery disease or stroke.
The new guidelines recommend open heart surgery for patients with complex coronary artery disease, as it provides better long-term survival and outcomes compared to stent placement. In contrast, patients with simpler disease can benefit from both surgical bypass and PCI, with complete revascularization being the preferred option.
A new genome analysis method predicts risk for coronary artery disease, breast cancer, and type 2 diabetes based on genetic variants. Up to 25 million people in the US may be at triple the normal risk for coronary artery disease, highlighting the potential for early interventions.
A study published in Radiology found that cardiac hybrid imaging, combining CT and nuclear stress testing, is an excellent long-term predictor of adverse cardiac events. The imaging approach helps identify stenosis and perfusion, providing critical information for treatment decisions.
Researchers at Florida State University emphasize the importance of early depression diagnosis in patients with coronary artery disease. Studies have shown that individuals with both CAD and depression experience significantly poorer health outcomes, including a two-fold higher risk of mortality. The article provides criteria for major...
The study reveals a tendency for duplication in the 9p21.3 sequence associated with coronary artery disease, which may affect predisposition to CAD. Sequence analysis shows varied repeats with 10-15 SNPs between each other and 82 SNPs between the human genome sequence.
Researchers found that hospitalized patients with coronary artery disease who developed low blood glucose levels during their stay had higher mortality rates, longer hospital stays, and increased healthcare costs. Frequent glucose monitoring could potentially save lives and decrease hospital length of stay and healthcare expenses.
Researchers found that imaging technologies more precisely predict who's at risk for heart attacks, allowing for timely prevention. The study used PET/CT imaging to measure coronary artery calcium, revealing existing disease and identifying patients at high risk.
A review published in the Journal of the American College of Cardiology suggests that environmental noise, including traffic noise, may contribute to the development of heart disease. The study proposes that noise induces a stress response, leading to vascular damage and increased risk of hypertension and diabetes.
A new multi-gene test predicts a high risk for early-onset heart disease in 1 out of 53 individuals, surpassing the prevalence of a rare genetic defect. The study suggests that combining polygenic screening with current testing could identify five-fold more cases with a genetic explanation.