Articles tagged with Diabetes
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A new NYU study successfully screens for diabetes using oral blood at dental visits, finding a 99% correlation with finger stick tests. The study's principal investigator believes dental visits could be an opportune site for diabetes screening among at-risk patients.
Pregnant women after bariatric surgery are at higher risk for complications like preterm birth and small babies, but lower risk of gestational diabetes. Maternal health services should provide extra care to these women.
Research suggests that heart failure patients who struggle with daily activities are at a higher risk of hospitalization and early death. The study found that older women, unmarried individuals, and those with chronic conditions such as obesity, dementia, anemia, and diabetes were more likely to experience these negative outcomes.
A study found that nearly half of patients with mental illness and a third of those with diabetes were not advised on dietary changes or physical activity. Health care providers may be missing opportunities to counsel high-risk patients about lifestyle modifications.
A new review finds that people with mild cognitive impairment are 65% more likely to develop dementia if they have diabetes and over twice as likely if they have psychiatric symptoms. Lifestyle changes such as a healthy diet and regular exercise may help prevent dementia.
Researchers developed a model to predict who stands to gain most from diabetes-preventing drugs or lifestyle changes like exercise and weight loss. The model identified seven key factors: fasting blood sugar, A1C level, triglycerides, family history of high blood sugar, waist measurement, height, and waist-to-hip ratio.
Non-alcoholic fatty liver disease (NAFLD) affects 25% of adults in the US, with excessive fat building up in liver cells. Researchers at BMC will investigate molecular mechanisms and identify novel treatments for NAFLD using retinoic acid and its nuclear receptor.
Research presented at the Saudi Heart Association conference reveals that 26% of participants are at high risk of having a heart attack or dying from a heart attack in 10 years. The study found that diabetes, obesity, and smoking were major contributors to this risk.
A 20-year study found that South Asian men have higher levels of tyrosine and several other amino acids associated with increased diabetes risk. Tyrosine was a stronger predictor of incident diabetes in South Asians, even after adjusting for obesity and insulin resistance.
A study published by UC Davis and Public Health Institute found that children exposed to tobacco smoke in utero are two to three times more likely to develop diabetes as adults. Birth weight did not affect the risk of developing diabetes.
Research from WashU suggests that poverty and inactivity are linked to diabetes prevalence, but only in certain areas. Localized approaches can target the most common predictors of diabetes in each region.
A study of 115,538 older patients with diabetes found that geriatric conditions were more common than diabetic complications, but their prevalence varied little by ethnicity. The research suggests that culturally competent care is essential for addressing disparities in this population.
A newly discovered protein called HKDC1 may be a genetic predictor for gestational hyperglycemia and its long-term health effects. The enzyme appears during pregnancy in women with less of the gene, which could lead to a predictive test and potential therapeutic targets.
Researchers at Stanford University School of Medicine identified limostatin, a hormone that decreases insulin levels during recovery from fasting or starvation, in fruit flies and found a similar protein in humans. This discovery has critical ramifications for understanding metabolism and may inform new efforts to combat diabetes.
The study, following 300 young people from age five since 2000, aims to test whether patterns of pancreatic function detected in childhood persist into adulthood. It will also explore the childhood origins of a range of new health problems, including dental and psychological health issues.
Researchers at Cornell University engineered a probiotic to secrete GLP-1, reducing high blood glucose by up to 30% in diabetic rats. The treatment mimics the function of pancreatic beta cells, shifting glucose control from the pancreas to the upper intestine.
A new study found that middle-aged heavy drinkers (more than two drinks daily) had a 34% higher risk of stroke compared to light drinkers. Heavy drinking also increased stroke risk in mid-life, regardless of genetic and early-life factors.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that women diagnosed with polycystic ovary syndrome (PCOS) are twice as likely to be hospitalized for reasons unrelated to reproductive health or injury. The study, which examined health records of over 2,500 women with PCOS, also foun...
Researchers at Penn Dental Medicine have identified Foxo1 as a critical molecule that impairs wound healing in diabetics. The study found that deleting Foxo1 in keratinocytes improved wound healing in diabetic mice, suggesting a potential target for therapies to boost healing.
A new study seeks to improve the health of sedentary people at risk for diabetes and heart disease by decreasing their sitting time. The program will test whether reducing sedentary behavior is as effective as increasing physical activity in improving overall health.
Researchers have identified a novel brain pathway that produces the hormone cholecystokinin (CCK), which acts as a crucial sensor of blood glucose levels. The discovery may lead to new treatments for hypoglycemia and its side effects, particularly in patients who suffer from unawareness due to repeated bouts of low blood sugar.
A recent study found that communities with higher levels of Indigenous language knowledge and cultural continuity have significantly lower diabetes rates, contrary to expectations. The research suggests that reconnecting Aboriginal Canadians to their cultural roots may be a crucial factor in addressing the epidemic of modern times.
Researchers at KU Leuven discovered genetically modified mice producing human growth hormone, altering insulin production and previous research findings. This unexpected turn reveals the need for reinterpretation of 250+ published diabetes studies.
Research found that umbilical cord-derived mesenchymal stromal cells from women with gestational diabetes have impaired growth, cellular senescence, and metabolic function. The study highlights the potential impact of gestational diabetes on the therapeutic potential of these stem cells.
Scientists have developed an ultra-thin, flexible device that sticks to skin like a rub-on tattoo and can detect glucose levels. The device has the potential to eliminate finger-pricking for people with diabetes, eliminating a major pain point in managing the disease.
A new research project funded by the Novo Nordisk Foundation will investigate why some diabetes patients develop painful neuritis, while others do not. The study aims to identify key factors and potentially develop preventive or inhibiting medicine.
A study found that nearly two-thirds of older adults with complex or very complex health status maintained tight blood sugar control, suggesting potential overtreatment. This vulnerable population is unlikely to benefit from intensive glucose management and may experience harms such as hypoglycemia.
A new study by Yale University researchers found that older diabetes patients often receive aggressive treatment despite questionable benefits. The study suggests a one-size-fits-all approach may be over-treating a substantial proportion of the population, increasing the risk of hypoglycemia.
A study published in Diabetologia found that black women working night shifts are more likely to develop diabetes than those who never work at night. The study revealed a stronger association in younger women, with increased risks of up to 39% after 10 or more years of night shift work.
Researchers found that blood sugar levels above 6.1 mmol/L increase the risk of early death, further hospitalizations, and diabetes in heart failure patients, even if they have normal blood sugar levels on arrival.
Researchers at Salk Institute develop a new compound called fexaramine that effectively stops weight gain, lowers cholesterol and controls blood sugar levels in mice. The pill tricks the body into thinking it has consumed calories, causing it to burn fat without altering appetite.
A study of 411 patients found that economic insecurity is associated with poor diabetes control and increased healthcare use. Material need insecurities, such as food insecurity and cost-related medication underuse, were significant predictors of poor diabetes control.
The American Diabetes Association is recommending that all people with diabetes take either moderate or high doses of statins to prevent heart disease. The revised Standards of Medical Care also call for a less stringent diastolic blood pressure goal of 90 mmHg, up from 80 mmHg.
Researchers have developed a safe and effective skin patch to deliver a drug that enhances the healing of diabetes-related ulcers. The patch has been shown to accelerate wound healing and prevent ulcer formation in mice, offering new hope for millions of people with diabetes.
A new study published in the Journal of Clinical Endocrinology & Metabolism found that urban stressors contribute to a rising rate of diabetes in developing nations. High cortisol levels were found to be a key factor, with urban residents having significantly higher levels than rural counterparts.
A clinical trial found no clear benefit of low glycemic index diets on key measures of heart disease and diabetes risk. Healthy eating habits focusing on fruits, vegetables, and whole grains are recommended by the study's lead researchers.
A new procedure combining surgery to remove part of the pancreas and islet cell transplantation appears safe and effective for alleviating pain from severe chronic pancreatitis. Eight out of nine patients who underwent this procedure were able to discontinue insulin use, with two requiring no insulin at all.
A new peptide developed by IU researchers has effectively cured lab animals of obesity, diabetes, and associated lipid abnormalities. The peptide combines the properties of three gastrointestinal hormones, GLP-1, GIP, and glucagon, and has shown unprecedented efficacy in reducing body weight and controlling metabolism.
Researchers from McMaster University have identified a key hormone responsible for reduced brown fat activity in obese individuals, leading to increased risk of obesity and diabetes. Blocking the production of peripheral serotonin enhances brown fat activity, providing a potential new treatment approach.
A new study published in The Lancet Diabetes and Endocrinology found that obesity can decrease life expectancy by up to 8 years. Researchers used data from the National Health and Nutrition Examination Survey to develop a model estimating annual risk of diabetes and cardiovascular disease in adults with different body weights.
A senior GP argues that UK government plans to extend diagnosis targets in primary care to six other conditions are problematic and unscientific. The data on which they are based is flawed, leading to potential overdiagnosis and unnecessary tests and treatments.
Researchers at Salk Institute discover that confining caloric consumption to an 8- to 12-hour period can significantly reduce weight gain, improve body composition, and even reverse obesity and diabetes in mice. The study's findings add to mounting evidence highlighting the importance of time-restricted eating for overall health.
A new study reveals that exercise following gastric bypass surgery provides additional benefits for obese patients, including improved insulin sensitivity and cardiovascular fitness. This clinical trial supports the inclusion of an exercise program after bariatric surgery to enhance overall health outcomes.
A new Drexel study finds that neighborhood and community-level factors play a significant role in diabetes risk, with areas of poverty, low education and high obesity rates having higher diabetes rates. The researchers report that improving the physical and social environment can reduce diabetes risk by up to 12%.
Researchers estimate that universal preconception care for pregnant women with diabetes can avert an estimated $5.5 billion in health expenditures and lost employment productivity over their children's lifetimes. Effective care could also help mitigate significant complications such as preterm deliveries, birth defects, and perinatal d...
A controlled diet study found that doubling saturated fat in the diet does not increase saturated fat in blood, but increases a fatty acid linked to diabetes and heart disease risk. Researchers also found improvements in blood glucose, insulin, and blood pressure with high-carb diets.
A study published in the Asia Pacific Journal of Clinical Nutrition found that adding one gram of turmeric to breakfast improved working memory in older adults with pre-diabetes. The spice's active compound, curcumin, has been shown to reduce the risk of dementia and improve cognitive function.
A randomized trial of 900 patients with diabetes found no benefit from routine CT angiography screening for coronary artery disease (CAD) in reducing mortality, heart attacks, or hospitalizations. The study suggests that guideline-directed medical therapy for hypertension and hyperlipidemia is effective in asymptomatic patients with di...
A new study by Intermountain Medical Center found that routine heart imaging screenings for diabetic patients at high risk of heart disease did not prevent heart attacks, hospitalization, or cardiac death. High-quality diabetes management remains the most effective way to avoid these events.
Researchers warn of increased bleeding risk from NSAIDs in atrial fibrillation patients and suggest alternative pain medications. Additionally, a study finds three in ten adults with diabetes remain undiagnosed, highlighting the need for improved care improvements.
A new analysis of current evidence suggests that expensive and cheaper drugs both work well in easing diabetes nerve pain. Considering the significant cost difference between medications, doctors should prioritize cost when prescribing treatments for diabetic neuropathy until more studies are done.
A five-year national initiative has shown promising results in reducing diabetes health disparities among African Americans, Latinos, and Native Americans. The Alliance model improves chronic disease management by strengthening care coordination, patient self-management, and community engagement.
A UAlberta team discovered a protein linked to metabolic regulation is critical in pulmonary hypertension development. Lower levels of Sirtuin3 have been found in patients with the disease, and gene therapy approaches show promise for improving symptoms.
Diabetic patients using insulin pumps are at risk of dosing errors if they forget to change the clock on their devices. This can lead to severe consequences, including hypoglycemia and hyperglycemia. Researchers call for increased awareness and education to ensure proper pump settings.
A new drug delivered through a skin patch has shown promise in healing diabetic foot ulcers and preventing their recurrence. The drug increases the protein HIF-1α, which helps form new blood vessels needed for wound healing.
A new study found that mothers with gestational diabetes and those who were overweight before pregnancy have daughters who are more likely to be obese. The research, published in Diabetes Care, suggests that behavior modifications during pregnancy may help reduce the risk of obesity in offspring.
A recent study suggests that moderate amounts of sunshine may help prevent obesity and diabetes by reducing glucose levels and insulin resistance. The researchers found that a compound called nitric oxide released by the skin after exposure to sunlight had beneficial effects on weight gain.
Researchers have found that high-fat diets can lead to brain inflammation and heart disease in male laboratory mice but not in female counterparts. The study suggests sex-specific nutritional guidance is needed for effective obesity treatment.
A study at Mount Sinai Hospital reveals that a set of molecules linked to insulin signaling in the brain may indicate an increased risk of developing diabetes. The researchers identified a key mechanism by which these molecules affect BCAA breakdown in the liver.
Dr. Mark Andermann's five-year $1.5 million grant will investigate neural pathways driving hunger and cravings, with the goal of understanding root causes of obesity and food addiction. His novel imaging techniques may lead to breakthroughs in treating these conditions.