Articles tagged with Diabetes
A study published in JAMA found that US diets improved between 1999 and 2012, with increased whole grain consumption and reduced sugar-sweetened beverages. However, disparities in diet quality persisted by race/ethnicity and income level.
Researchers discovered weaker electric currents in diabetic wounds, which can lead to delayed healing and increase the risk of complications. This finding opens up new avenues for managing diabetic patients and could have significant implications for reducing healthcare costs associated with chronic ulcers and wounds.
A study published in Scientific Reports found that vitamin D lowers the risk of developing hyperglycaemia when taken with atypical antipsychotics like quetiapine. The researchers also confirmed this finding using mouse tests, revealing that vitamin D defends against the insulin-lowering effects of quetiapine.
Researchers are examining DNA samples from 20,000 people with diabetes to identify genetic factors in diabetic kidney disease. The study aims to develop new tests and treatments to prevent kidney complications and improve patient outcomes.
African American men with high West African genetic ancestry have lower waist circumference and waist-hip ratio, indicating reduced central adiposity. In contrast, African American women do not show a similar association, suggesting that genes from West Africa may offer protection against obesity in men but not women.
The DFG has approved a second funding period for TU Dresden's Collaborative Research Centre CRC 940, investigating the cognitive and neural mechanisms underlying self-control and volitional action. The centre aims to elucidate impairments of self-control in mental disorders such as addictions or eating disorders.
A new study reveals that the splicing regulator RBFOX2 plays a key role in diabetic cardiomyopathy, impairing normal gene expression patterns and leading to abnormal calcium signaling in the heart. This understanding may lead to the development of new tools for diagnosing, preventing or treating this form of heart damage.
A national study led by Michigan State University sociologist Hui Liu found that for men, an unhappy marriage may actually slow the development of diabetes and promote successful treatment once they do get the disease. Women with good-quality marriages were more likely to have a lower risk of developing diabetes five years later.
A study found that urban neighborhoods with more walkable design have lower rates of overweight, obesity, and diabetes compared to less walkable areas. The prevalence of these conditions increased in less walkable neighborhoods between 2001 and 2012.
Adults under 40 are not being sufficiently screened for lipid abnormalities while taking antipsychotics, which increases cardiovascular risk. Improved screening of this age group is crucial for early detection and intervention.
A new study found that air pollution exposure can worsen blood sugar levels, cholesterol and other risk factors for heart disease. Participants with diabetes experienced higher changes in blood glucose and cholesterol levels when exposed to higher levels of particulate matter.
A recent study published by the European Society of Cardiology found that nearly 25,000 patients developed heart failure within four years of their first heart attack. The risk factors for this condition include older age, socioeconomic deprivation, and comorbidities such as diabetes.
A study published in the Journal of the American Osteopathic Association found that a common blood test can detect hidden diabetes in hospitalized patients with hyperglycemia. The HbA1C test was used to diagnose diabetes in 31 patients, and 77% had results consistent with diabetes diagnosis.
A new 20-year study shows that higher levels of cardiorespiratory fitness significantly reduce the risk of developing prediabetes or diabetes. The research found an 8-11% increase in fitness level to be associated with a 0.1% lower risk, highlighting the importance of exercise programs for reducing these conditions.
Research found a significant increase in first-time stroke hospitalizations among young Danish adults between 1994 and 2012. The study suggests lifestyle-related risk factors, such as diabetes and obesity, may contribute to this trend.
A novel intraocular therapy has been shown to prevent or reverse diabetic retinopathy in mice by increasing ACE-2 expression. The study found that the therapy reduced pro-inflammatory cells and reversed vascular degeneration, suggesting a potential new treatment for blindness and other vascular diseases.
Researchers found that increased insulin signaling reduces atherosclerosis development and improves aorta function in atherosclerosis-prone mice. The anti-atherogenic effects were linked to induction of nitric oxide and activation of downstream pathways, including endothelin receptor B (EDNRB).
A study of 295,420 infants in Bavaria found increased T1D risk associated with respiratory tract infections between 2-9 months and 3-5.9 months of age. Early exposure to viral infections may impair immune system response, suggesting a crucial first half-year of life for autoimmunity development.
A McMaster University research team is examining how environmental factors, such as agricultural practices and toxicants, affect brown adipose tissue activity in individuals with obesity or type-2 diabetes. The studies aim to develop new strategies to enhance BAT activity for treating and preventing these diseases.
A new study reveals that nerve damage occurs before vessel damage in the retina due to diabetes, contradicting long-held beliefs. This finding has significant implications for treatment and prevention strategies.
The University of Texas at Austin researchers have developed an injectable, regenerative gel that delivers proteoglycans and a growth factor to stimulate the growth of blood vessels and restore blood flow in the lower limbs. The treatment has shown promising results in mice with ischemia and diabetes, with 85% recovery of blood vessels.
Researchers have developed a non-invasive method for receptor activation using red light, which can penetrate deep tissues and activate signal pathways involved in cell division. The approach has potential for treating diseases such as cancer, Alzheimer, Parkinson, and diabetes.
Researchers argue that health systems need leaders who can think like designers to address complex challenges like obesity, diabetes, and cost control. Design thinking offers tools for empathy, radical collaboration, and rapid prototyping to innovate and improve healthcare.
A healthy diet has been found to significantly reduce the risk of high blood pressure in women with a history of pregnancy-related diabetes. Over a 22-year follow-up period, researchers discovered that women who adhered to a healthy diet were 20% less likely to develop high blood pressure.
Research published in Diabetologia found that people with diabetes face reduced overall life expectancy and higher numbers of years living with disability compared to those without diabetes. The study estimated a loss of 3-9 years of life expectancy and 8-9 years of disability-free life expectancy for men and women with diabetes.
Researchers track NADPH production through a novel pathway, revealing an environmental-dependent switch between two recognized routes. The findings have implications for diseases such as cancer and diabetes, highlighting the importance of understanding NADPH pathways in cellular processes.
Research from the University of Cambridge finds that babies of obese women with gestational diabetes are already abnormally large by 20 weeks, suggesting current screening may be too late. This could lead to lasting health impacts on the offspring, including obesity and diabetes in later life.
Regular exercise can counteract health problems associated with sitting all day, according to a new study published in BMC Public Health. The research found that people who are physically active have a more desirable health profile compared to those who are inactive and spend high amounts of time sitting.
Research from the University of California, Irvine, reveals that controlling blood pressure, blood sugar, and LDL-cholesterol levels reduces the risk of cardiovascular disease in people with diabetes. Only 7 percent of diabetic participants met recommended levels in a major heart study.
A new study published in Diabetologia found that the GLP-1 analog drug liraglutide decreases activation in the brain's cortex when individuals are shown images of desirable foods, making these foods less appealing. This suggests that liraglutide may be an effective weight loss therapy for people who tend to eat as a reward.
A Paleolithic-type diet improved insulin sensitivity, reduced abdominal adiposity and body weight in obese postmenopausal women. The diet high in polyunsaturated fatty acids may have long-term beneficial effects on obesity-related disorders.
The study found that women have a significantly higher prevalence of peripheral artery disease, while men have a higher prevalence of carotid artery stenosis and abdominal aortic aneurysms. Diabetes is also identified as a major risk factor for developing PVD, even in patients without heart disease.
Taking long naps or being excessively tired during the day is linked to a higher risk of developing metabolic syndrome, which includes high blood pressure, high cholesterol, and obesity. The study found that napping for 40 minutes or longer was associated with a significant increase in metabolic syndrome risk.
Researchers found that a poor diet and lack of exercise accelerate cellular senescence and age-related conditions in mice. Exercise was shown to prevent premature senescent cell accumulation and protect against unhealthy diet-induced damage.
A study found that white patients and those with lower incomes were slower to discontinue diabetes medication rosiglitazone after a FDA safety alert. Patients living in higher- versus lowest-socioeconomic status communities discontinued the drug significantly earlier.
Researchers at UNC and NC State create a synthetic patch filled with natural beta cells that can secrete insulin on demand, avoiding rejection risks and hypoglycemia. The 'smart cell patch' demonstrated successful blood sugar regulation in small animal models of type-1 diabetes.
Men with fertility problems are at higher risk of metabolic diseases such as osteoporosis and diabetes. Researchers found that one-third of infertile men under 50 have biochemical signs of low sex hormone levels, which can lead to fractures and increased glucose levels.
Researchers discovered that human brown fat cells show circadian fluctuations in glucose consumption, which may act as a glucose buffer and lessen the stress on the pancreas. Individuals with high brown fat abundance showed less variability in glucose levels over time.
A recent study found that African Americans have a higher risk of hypertension, diabetes, and kidney failure compared to whites, even after adjusting for genetic variants. Most blacks with the high-risk APOL1 gene variant experienced similar decline in kidney function as those without the variant.
A study of Android diabetes apps found that 81% lacked privacy policies and 76% shared sensitive health information without consent. The apps' transmission of data to third parties poses significant privacy risks, as there are no federal legal protections against the sale or disclosure of medical app data.
A new Pacific-Rim Trade Agreement may limit access to medicines for patients with diabetes. Research suggests that Renin-Angiotensin System (RAS) blockers can have similar effects on cardiovascular and renal outcomes as other treatments.
A study of 5,644 women found that diabetes treatment decreases mammographic density, while insulin use increases it. The researchers also urge women with and without diabetes to adopt simple lifestyle changes to reduce breast cancer risk.
A University of Florida study found that less than one-quarter of patients with prediabetes received treatment from their primary care physician. Prediabetes is a common condition that increases the risk of vascular problems and diabetes, yet many people remain undiagnosed or untreated.
Ultrawide field (UWF) scanning technology improved the ability to identify diabetic retinopathy in patients and judge the need for follow-up examinations or treatment. The study found that UWF imaging reduced ungradable images by 81% compared to traditional digital retinal photographs.
A new study from Ohio State University found that men and women with higher levels of linoleic acid tend to have less heart-threatening fat, more lean body mass, and lower inflammation. Higher linoleic acid levels also meant lower likelihood of insulin resistance and diabetes.
Researchers found that a cell aging program increases insulin secretion in human and mouse pancreatic beta cells, improving their function. This discovery suggests that cellular aging can bring unexpected benefits to the production of insulin, potentially leading to new insights and treatments for diabetes.
The new issue of the Annals of Global Health presents a core set of recommendations for optimizing diabetes care globally. The main findings emphasize the need for each nation to assess region-specific epidemiology, establish public health imperatives, and commit to education and research to advance culturally-sensitive guidelines.
Direct-to-consumer genetic testing raises concerns about physicians' preparedness to discuss test results and potential downstream effects on the healthcare system. A study found that only a minority of consumers share their results with their doctor, often due to physician's inability to answer questions and address patient concerns.
Scientists at the University of Michigan have developed a novel method to observe insulin production in the pancreas of living animals. The technique allows researchers to see how much insulin is present and respond to sugar levels in real-time, revealing surprising insights into pancreatic function.
A new study published in Nutrition and Diabetes journal found that low-carbohydrate, high-fat diets can lead to rapid weight gain and worsen glucose intolerance. The research suggests that fad diets like Paleo may not be suitable for people with pre-diabetes or diabetes.
Researchers found that diseased exocrine tissue can cause deficiencies in endocrine cells, leading to diabetes. The discovery suggests a new target for stem cell-based treatments.
A new study published in Breastfeeding Medicine found a significant association between diabetes during pregnancy and low milk supply. Women with maternal glucose intolerance were more likely to experience lactation difficulties, highlighting the need for targeted therapies to support breastfeeding mothers.
Scientists discover that activating mTOR pathway plays a critical role in beiging of white fat cells to fight diabetes. Rapamycin, a drug previously used as an immunosuppressant, is found to induce beige fat cell formation and improve glucose metabolism.
Red raspberries contain essential nutrients like vitamin C and fiber, which may help reduce the risk of metabolically-based chronic diseases. The polyphenolic components in red raspberries have been shown to reduce oxidative stress and inflammation, making them a promising food for heart health and brain function.
A new study finds that only 9% of weight loss programs adhere to expert medical guidelines, leaving consumers unclear about their regimen. The majority of programs lack essential components like high-intensity interventions and moderate physical activity.
Researchers aim to optimize synthetic ERRγ activators for potency and selectivity to advance treatments for various diseases. Previous studies in animal models suggest increased expression of ERRγ improves exercise capacity and mitochondrial function.
Researchers found that blacks, Latinos and Asians had lower risk of coronary heart disease compared to whites without diabetes or prior history of heart disease. The study suggests systematic efforts by Kaiser Permanente may help reduce racial disparities in health care.
Researchers found that older adults with diabetes who received structured depression care management were 53% less likely to die compared to those receiving usual care. This treatment also improved depression symptoms more effectively.
A study by Finnish researchers found that removing a gene from mice protected them against arterial disease and obesity, due to increased activity of brown adipose tissue. The discovery suggests that inhibiting the USF1 gene might be a good strategy for treating cardiovascular disease and diabetes.
Researchers at Dresden University Hospital have discovered a molecular signal pathway that allows stem cells and pancreatic islet cells to interpret signals in a similar manner. This finding could lead to new approaches for regenerating damaged tissue and treating metabolic diseases such as diabetes.