Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
Researchers found that obese individuals with insulin resistance showed improvement by avoiding AGEs, a byproduct of dry heat-cooked foods. A diet low in AGEs reduced insulin resistance, body weight, and AGE levels.
A new study by a UC Santa Barbara researcher reveals that Latinos age at a slower rate than other ethnic groups. The findings, published in Genome Biology, may one day help scientists understand how to slow the aging process for everyone.
A recent study published in Diabetes Care journal reveals a significant rise in diabetes-related vision loss worldwide. The 20-year period saw a 64% increase in people with moderate or severe vision impairment due to diabetes, primarily attributed to poor glucose control and limited access to eye health services.
Erika Eggers is studying retinal cell signaling's role in light adaptation and diabetic retinopathy, which may lead to the development of cell-based models for drug treatments. Researchers have found that neural activity in the retina changes before diabetic retinopathy sets in.
A RAND Corporation study found that people who gained health coverage under the Affordable Care Act's expansion increased their prescription drug use by 28% and had lower out-of-pocket spending. Those with chronic conditions saw even larger increases in prescriptions filled and reductions in costs.
A study led by SFU health sciences professor Ruth Lavergne found that BC's primary care physician incentive program has not improved access to primary care or reduced hospitalizations. The program, which provided over $240 million in incentive payments since 2007, has also failed to save money.
A simple phone checklist can help detect telltale changes in health status of people receiving nonmedical home care, according to a pilot study. Changes in clinical status occur relatively common, with 2% of caregiver shifts and 2% of recipients affected.
A multinational study of over 4,700 children aged 9-11 years found a significant link between maternal gestational diabetes and childhood obesity. The researchers discovered that children of mothers with gestational diabetes had a 53% higher risk of obesity, 73% for central obesity, and 42% for high body fat.
The study found that patients with diabetes and solid-organ malignancies had significantly more frequent hospitalizations and multiple hospitalizations compared to those without diabetes. Hospital stay was also longer on average for diabetic patients.
A study of US adults with diabetes found that overall diabetic kidney disease prevalence remained stable from 1988 to 2014, while albuminuria declined and reduced estimated glomerular filtration rate (eGFR) increased. The prevalence of reduced eGFR was higher among younger and non-Hispanic white populations.
A study by University of Washington researchers found that the prevalence of diabetic kidney disease has remained relatively stable over 30 years, but its clinical manifestations have changed significantly. Albuminuria rates decreased, while reduced glomerular filtration rate increased.
A study published in The BMJ found that higher total physical activity levels are strongly associated with a lower risk of five common chronic diseases. Most health gains occur at a level of 3000-4000 MET minutes a week, suggesting that current recommended minimum levels may not be sufficient to achieve larger reductions in risks.
A 15-year decline in heart attacks was reported among Kaiser Permanente members in Northern California, with a notable reduction in severe heart attacks. The decline was consistent across demographics and risk groups, driven by reductions in less severe heart attacks.
Researchers found lifestyle modification programs, modeled on diabetes prevention programs, resulted in weight reduction and additional metabolic benefits such as reduced blood sugar, blood pressure, and cholesterol levels. Programs with maintenance components showed larger benefits.
The University of Minnesota, Medica Research Institute, and HealthPartners Institute will study the impact of the Patient Centered Medical Home model on diabetes care in Minnesota. The research aims to identify specific changes in primary care offices that have improved health outcomes for patients with diabetes.
The study found a weighted prevalence of diabetes among US adolescents aged 12 to 19 years to be 0.8 percent, with 29 percent being undiagnosed. Prediabetes was more common in males than females and varied significantly across ethnic groups.
A new Australian-first study found that nearly half of patients hospitalized due to diabetic foot disease were already showing symptoms. Diabetic foot disease causes significant costs, with estimated annual direct costs reaching $350 million for hospitalization alone.
A recent study published in Diabetologia found that moderate-intensity exercise was as effective as a combination of diet and exercise in improving glucose control for individuals with pre-diabetes. Moderate exercise was shown to provide nearly the same benefit on glucose tolerance as the gold standard of fat and calorie restriction al...
A Drexel University study reveals that sugary soft drinks are 160% more expensive per fluid ounce than healthier alternative milk. Taxing sugary beverages could help level the price difference and encourage healthier options, with a potential impact on lower-income consumers.
Researchers at Helmholtz Munich discovered a new marker, Flattop, that subdivides insulin-producing beta cells into mature and immature subgroups. The study suggests that the Flattop-negative cells are a reserve pool for replenishing mature beta cells.
A new US recommendation for diabetes screening may only detect half of adults with undiagnosed dysglycemia, particularly among racial and ethnic minorities. The study found that the detection rate drops to 50.3% for Blacks and 37.7% for Hispanic/Latino patients compared to 54.5% for whites.
A new study found that the latest government guidelines for diabetes screening missed 55% of high-risk individuals with prediabetes or diabetes. Racial and ethnic minorities were disproportionately affected, with only 50% of African-American patients and 37% of Latino patients falling within the recommended age and weight ranges.
A randomized controlled trial found that changes in pain and physical function did not differ between patients wearing unloading shoes or conventional walking shoes. The study suggests that choosing one type of shoe over the other may not significantly impact symptoms for knee osteoarthritis sufferers.
A new study found that recurrent diabetic ketoacidosis is associated with substantial mortality, particularly among young, socially disadvantaged adults with type 1 diabetes. The median age at death was just 32 in patients with 5 or more DKA admissions compared to 53 in those with fewer admissions.
A study found that severe non-proliferative and proliferative diabetic retinopathy stages are associated with increased depressive symptoms in people with diabetes. Moderate or severe vision impairment, but not diabetic macular edema, contributed to the risk of depression.
Researchers at the Buck Institute discover metformin reduces toxic acid levels associated with Maple Syrup Urine Disease, a disorder identified 1 in 180,000 births. Metformin treatment significantly reduced ketoacid buildup in skeletal muscle of mice and toxic acid levels in human skin cells.
A new study found that both limited and excess sleep may raise diabetes risk in men, with those sleeping too much or too little having impaired glucose metabolism. In contrast, women who slept less or more than average were more responsive to insulin and had enhanced beta-cell function.
A meta-analysis of studies shows oral aloe vera use is associated with significant decreases in fasting blood glucose (FBG) and hemoglobin A1c (HbA1c). The greatest benefits may be seen in individuals with FBG >200 mg/dL.
African Americans with diabetes are at increased risk of stroke, coronary heart disease, and cardiovascular mortality. The study found that assessing kidney function can help identify individuals with elevated cardiovascular risks.
A recent study published in the Journal of Epidemiology and Community Health found that people with diabetes are at a 56% increased risk of dying from a STEMI heart attack and a 39% increased risk of dying from a NSTEMI heart attack compared to those without diabetes. Researchers tracked over 700,000 people who had been admitted to hos...
Researchers found that glucosamine plays a critical role in early embryonic development, helping embryos proliferate normally. This could aid in avoiding birth defects in diabetic pregnancies and improving future stem-cell treatments. Glucosamine is also essential for embryonic cells to grow and develop.
A new study published in CardioRenal Medicine suggests that patients with more inflammation prior to kidney transplantation are at higher risk of developing diabetes after surgery. The researchers also found that a patient's fat stores play a role in this process, and that reducing inflammation before transplant may help prevent diabetes.
A study published in JAMA found that US diets improved between 1999 and 2012, with increased whole grain consumption and reduced sugar-sweetened beverages. However, disparities in diet quality persisted by race/ethnicity and income level.
Researchers discovered weaker electric currents in diabetic wounds, which can lead to delayed healing and increase the risk of complications. This finding opens up new avenues for managing diabetic patients and could have significant implications for reducing healthcare costs associated with chronic ulcers and wounds.
A study published in Scientific Reports found that vitamin D lowers the risk of developing hyperglycaemia when taken with atypical antipsychotics like quetiapine. The researchers also confirmed this finding using mouse tests, revealing that vitamin D defends against the insulin-lowering effects of quetiapine.
Researchers are examining DNA samples from 20,000 people with diabetes to identify genetic factors in diabetic kidney disease. The study aims to develop new tests and treatments to prevent kidney complications and improve patient outcomes.
African American men with high West African genetic ancestry have lower waist circumference and waist-hip ratio, indicating reduced central adiposity. In contrast, African American women do not show a similar association, suggesting that genes from West Africa may offer protection against obesity in men but not women.
The DFG has approved a second funding period for TU Dresden's Collaborative Research Centre CRC 940, investigating the cognitive and neural mechanisms underlying self-control and volitional action. The centre aims to elucidate impairments of self-control in mental disorders such as addictions or eating disorders.
A new study reveals that the splicing regulator RBFOX2 plays a key role in diabetic cardiomyopathy, impairing normal gene expression patterns and leading to abnormal calcium signaling in the heart. This understanding may lead to the development of new tools for diagnosing, preventing or treating this form of heart damage.
A national study led by Michigan State University sociologist Hui Liu found that for men, an unhappy marriage may actually slow the development of diabetes and promote successful treatment once they do get the disease. Women with good-quality marriages were more likely to have a lower risk of developing diabetes five years later.
A study found that urban neighborhoods with more walkable design have lower rates of overweight, obesity, and diabetes compared to less walkable areas. The prevalence of these conditions increased in less walkable neighborhoods between 2001 and 2012.
Adults under 40 are not being sufficiently screened for lipid abnormalities while taking antipsychotics, which increases cardiovascular risk. Improved screening of this age group is crucial for early detection and intervention.
A new study found that air pollution exposure can worsen blood sugar levels, cholesterol and other risk factors for heart disease. Participants with diabetes experienced higher changes in blood glucose and cholesterol levels when exposed to higher levels of particulate matter.
A recent study published by the European Society of Cardiology found that nearly 25,000 patients developed heart failure within four years of their first heart attack. The risk factors for this condition include older age, socioeconomic deprivation, and comorbidities such as diabetes.
A study published in the Journal of the American Osteopathic Association found that a common blood test can detect hidden diabetes in hospitalized patients with hyperglycemia. The HbA1C test was used to diagnose diabetes in 31 patients, and 77% had results consistent with diabetes diagnosis.
A new 20-year study shows that higher levels of cardiorespiratory fitness significantly reduce the risk of developing prediabetes or diabetes. The research found an 8-11% increase in fitness level to be associated with a 0.1% lower risk, highlighting the importance of exercise programs for reducing these conditions.
Research found a significant increase in first-time stroke hospitalizations among young Danish adults between 1994 and 2012. The study suggests lifestyle-related risk factors, such as diabetes and obesity, may contribute to this trend.
A novel intraocular therapy has been shown to prevent or reverse diabetic retinopathy in mice by increasing ACE-2 expression. The study found that the therapy reduced pro-inflammatory cells and reversed vascular degeneration, suggesting a potential new treatment for blindness and other vascular diseases.
Researchers found that increased insulin signaling reduces atherosclerosis development and improves aorta function in atherosclerosis-prone mice. The anti-atherogenic effects were linked to induction of nitric oxide and activation of downstream pathways, including endothelin receptor B (EDNRB).
A study of 295,420 infants in Bavaria found increased T1D risk associated with respiratory tract infections between 2-9 months and 3-5.9 months of age. Early exposure to viral infections may impair immune system response, suggesting a crucial first half-year of life for autoimmunity development.
A McMaster University research team is examining how environmental factors, such as agricultural practices and toxicants, affect brown adipose tissue activity in individuals with obesity or type-2 diabetes. The studies aim to develop new strategies to enhance BAT activity for treating and preventing these diseases.
A new study reveals that nerve damage occurs before vessel damage in the retina due to diabetes, contradicting long-held beliefs. This finding has significant implications for treatment and prevention strategies.
The University of Texas at Austin researchers have developed an injectable, regenerative gel that delivers proteoglycans and a growth factor to stimulate the growth of blood vessels and restore blood flow in the lower limbs. The treatment has shown promising results in mice with ischemia and diabetes, with 85% recovery of blood vessels.
Researchers have developed a non-invasive method for receptor activation using red light, which can penetrate deep tissues and activate signal pathways involved in cell division. The approach has potential for treating diseases such as cancer, Alzheimer, Parkinson, and diabetes.
A healthy diet has been found to significantly reduce the risk of high blood pressure in women with a history of pregnancy-related diabetes. Over a 22-year follow-up period, researchers discovered that women who adhered to a healthy diet were 20% less likely to develop high blood pressure.
Researchers argue that health systems need leaders who can think like designers to address complex challenges like obesity, diabetes, and cost control. Design thinking offers tools for empathy, radical collaboration, and rapid prototyping to innovate and improve healthcare.
Research published in Diabetologia found that people with diabetes face reduced overall life expectancy and higher numbers of years living with disability compared to those without diabetes. The study estimated a loss of 3-9 years of life expectancy and 8-9 years of disability-free life expectancy for men and women with diabetes.
Researchers track NADPH production through a novel pathway, revealing an environmental-dependent switch between two recognized routes. The findings have implications for diseases such as cancer and diabetes, highlighting the importance of understanding NADPH pathways in cellular processes.
Research from the University of Cambridge finds that babies of obese women with gestational diabetes are already abnormally large by 20 weeks, suggesting current screening may be too late. This could lead to lasting health impacts on the offspring, including obesity and diabetes in later life.
Regular exercise can counteract health problems associated with sitting all day, according to a new study published in BMC Public Health. The research found that people who are physically active have a more desirable health profile compared to those who are inactive and spend high amounts of time sitting.