Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
Research from the University of California, Irvine, reveals that controlling blood pressure, blood sugar, and LDL-cholesterol levels reduces the risk of cardiovascular disease in people with diabetes. Only 7 percent of diabetic participants met recommended levels in a major heart study.
A new study published in Diabetologia found that the GLP-1 analog drug liraglutide decreases activation in the brain's cortex when individuals are shown images of desirable foods, making these foods less appealing. This suggests that liraglutide may be an effective weight loss therapy for people who tend to eat as a reward.
A Paleolithic-type diet improved insulin sensitivity, reduced abdominal adiposity and body weight in obese postmenopausal women. The diet high in polyunsaturated fatty acids may have long-term beneficial effects on obesity-related disorders.
The study found that women have a significantly higher prevalence of peripheral artery disease, while men have a higher prevalence of carotid artery stenosis and abdominal aortic aneurysms. Diabetes is also identified as a major risk factor for developing PVD, even in patients without heart disease.
Taking long naps or being excessively tired during the day is linked to a higher risk of developing metabolic syndrome, which includes high blood pressure, high cholesterol, and obesity. The study found that napping for 40 minutes or longer was associated with a significant increase in metabolic syndrome risk.
Researchers found that a poor diet and lack of exercise accelerate cellular senescence and age-related conditions in mice. Exercise was shown to prevent premature senescent cell accumulation and protect against unhealthy diet-induced damage.
A study found that white patients and those with lower incomes were slower to discontinue diabetes medication rosiglitazone after a FDA safety alert. Patients living in higher- versus lowest-socioeconomic status communities discontinued the drug significantly earlier.
Researchers at UNC and NC State create a synthetic patch filled with natural beta cells that can secrete insulin on demand, avoiding rejection risks and hypoglycemia. The 'smart cell patch' demonstrated successful blood sugar regulation in small animal models of type-1 diabetes.
Men with fertility problems are at higher risk of metabolic diseases such as osteoporosis and diabetes. Researchers found that one-third of infertile men under 50 have biochemical signs of low sex hormone levels, which can lead to fractures and increased glucose levels.
A recent study found that African Americans have a higher risk of hypertension, diabetes, and kidney failure compared to whites, even after adjusting for genetic variants. Most blacks with the high-risk APOL1 gene variant experienced similar decline in kidney function as those without the variant.
Researchers discovered that human brown fat cells show circadian fluctuations in glucose consumption, which may act as a glucose buffer and lessen the stress on the pancreas. Individuals with high brown fat abundance showed less variability in glucose levels over time.
A new Pacific-Rim Trade Agreement may limit access to medicines for patients with diabetes. Research suggests that Renin-Angiotensin System (RAS) blockers can have similar effects on cardiovascular and renal outcomes as other treatments.
A study of 5,644 women found that diabetes treatment decreases mammographic density, while insulin use increases it. The researchers also urge women with and without diabetes to adopt simple lifestyle changes to reduce breast cancer risk.
A University of Florida study found that less than one-quarter of patients with prediabetes received treatment from their primary care physician. Prediabetes is a common condition that increases the risk of vascular problems and diabetes, yet many people remain undiagnosed or untreated.
Ultrawide field (UWF) scanning technology improved the ability to identify diabetic retinopathy in patients and judge the need for follow-up examinations or treatment. The study found that UWF imaging reduced ungradable images by 81% compared to traditional digital retinal photographs.
A study of Android diabetes apps found that 81% lacked privacy policies and 76% shared sensitive health information without consent. The apps' transmission of data to third parties poses significant privacy risks, as there are no federal legal protections against the sale or disclosure of medical app data.
Researchers found that a cell aging program increases insulin secretion in human and mouse pancreatic beta cells, improving their function. This discovery suggests that cellular aging can bring unexpected benefits to the production of insulin, potentially leading to new insights and treatments for diabetes.
A new study from Ohio State University found that men and women with higher levels of linoleic acid tend to have less heart-threatening fat, more lean body mass, and lower inflammation. Higher linoleic acid levels also meant lower likelihood of insulin resistance and diabetes.
The new issue of the Annals of Global Health presents a core set of recommendations for optimizing diabetes care globally. The main findings emphasize the need for each nation to assess region-specific epidemiology, establish public health imperatives, and commit to education and research to advance culturally-sensitive guidelines.
Direct-to-consumer genetic testing raises concerns about physicians' preparedness to discuss test results and potential downstream effects on the healthcare system. A study found that only a minority of consumers share their results with their doctor, often due to physician's inability to answer questions and address patient concerns.
Scientists at the University of Michigan have developed a novel method to observe insulin production in the pancreas of living animals. The technique allows researchers to see how much insulin is present and respond to sugar levels in real-time, revealing surprising insights into pancreatic function.
Researchers found that diseased exocrine tissue can cause deficiencies in endocrine cells, leading to diabetes. The discovery suggests a new target for stem cell-based treatments.
A new study published in Nutrition and Diabetes journal found that low-carbohydrate, high-fat diets can lead to rapid weight gain and worsen glucose intolerance. The research suggests that fad diets like Paleo may not be suitable for people with pre-diabetes or diabetes.
A new study published in Breastfeeding Medicine found a significant association between diabetes during pregnancy and low milk supply. Women with maternal glucose intolerance were more likely to experience lactation difficulties, highlighting the need for targeted therapies to support breastfeeding mothers.
Scientists discover that activating mTOR pathway plays a critical role in beiging of white fat cells to fight diabetes. Rapamycin, a drug previously used as an immunosuppressant, is found to induce beige fat cell formation and improve glucose metabolism.
Red raspberries contain essential nutrients like vitamin C and fiber, which may help reduce the risk of metabolically-based chronic diseases. The polyphenolic components in red raspberries have been shown to reduce oxidative stress and inflammation, making them a promising food for heart health and brain function.
A new study finds that only 9% of weight loss programs adhere to expert medical guidelines, leaving consumers unclear about their regimen. The majority of programs lack essential components like high-intensity interventions and moderate physical activity.
Researchers aim to optimize synthetic ERRγ activators for potency and selectivity to advance treatments for various diseases. Previous studies in animal models suggest increased expression of ERRγ improves exercise capacity and mitochondrial function.
Researchers found that blacks, Latinos and Asians had lower risk of coronary heart disease compared to whites without diabetes or prior history of heart disease. The study suggests systematic efforts by Kaiser Permanente may help reduce racial disparities in health care.
Researchers found that older adults with diabetes who received structured depression care management were 53% less likely to die compared to those receiving usual care. This treatment also improved depression symptoms more effectively.
A study by Finnish researchers found that removing a gene from mice protected them against arterial disease and obesity, due to increased activity of brown adipose tissue. The discovery suggests that inhibiting the USF1 gene might be a good strategy for treating cardiovascular disease and diabetes.
Researchers at Dresden University Hospital have discovered a molecular signal pathway that allows stem cells and pancreatic islet cells to interpret signals in a similar manner. This finding could lead to new approaches for regenerating damaged tissue and treating metabolic diseases such as diabetes.
A study found that two consecutive nights of extended sleep can counteract the increased risk of diabetes associated with short-term sleep restriction during the work week. Insulin sensitivity and diabetes risk returned to normal after two nights of extended sleep.
A large new study found previously unknown risk factors associated with keratoconus, a condition that causes progressive nearsightedness at a young age. The study revealed higher odds of developing keratoconus among men, African Americans, Latinos, and those with asthma and sleep apnea.
A study published in The BMJ found that higher potato consumption before pregnancy increases the risk of gestational diabetes. Swapping potatoes for other vegetables, legumes, or whole grains may lower this risk, possibly due to their lower glycaemic index.
Adults with severe obesity who spend more time sitting are at higher risk of cardiovascular and metabolic diseases. Replacing sedentary behavior with low-intensity physical activities may improve cardiometabolic health.
Researchers at the Gladstone Institutes have successfully converted human skin cells into fully-functional insulin-producing pancreatic cells. These new cells protected mice from developing diabetes in a mouse model of the disease, offering a promising approach to personalized cell therapy for patients with diabetes.
A new study published in the American Journal of Obstetrics and Gynecology found that metformin decreases the production of toxins elevated in preeclampsia and helps heal injured blood vessels. The drug is considered safe during pregnancy, offering a potential new treatment option for women with preeclampsia.
Professor Ian Craddock discusses how IoT technologies can transform health care and reduce costs by managing chronic conditions outside the hospital environment. He will explore challenges, security concerns, and application scenarios for healthcare using his SPHERE project as an example.
A Massachusetts General Hospital study found that unmet socioeconomic needs, such as difficulty affording food or transportation, are directly related to poor health outcomes. Patients with unmet needs were more likely to have chronic conditions like diabetes and hypertension.
A recent study by Ben-Gurion University researchers found that individuals with diabetic foot complications suffer from significantly impaired cognitive function. Cognitive abilities such as memory, concentration, and learning are affected, with patients exhibiting slower responses and decreased verbal fluency.
A Stanford study found that infertile men have a higher risk of developing heart disease, diabetes, and other health problems. The research suggests that male infertility is associated with increased rates of mortality and general health issues, even after adjusting for obesity and smoking.
A recent study found that a reform model aimed at improving coordinated care for individuals with mental health diagnoses has yet to deliver desired results. The Blue Cross Blue Shield of Massachusetts Alternative Quality Contract, which began in 2009, was designed to encourage high-value care and improve quality coordination, but its ...
Pharmaceutical sales representatives are screening people in India for their products, raising concerns about unchecked conflicts of interest and potential harm to patients. Local residents receive medical testing at 'health camps,' some organized by Indian drug firms and pharmaceutical companies like Abbott and Roche.
The global diet is getting sweeter, particularly when it comes to beverages, with many packaged foods containing caloric sweeteners. The World Health Organization promotes initiatives to reduce intake, but policies face challenges such as a lack of consensus on low-calorie sweetener substitutes.
Kyungsuk Yum, a UTA researcher, is developing an injectable nanoscale device that continuously monitors blood glucose levels and transmits readings to a scanner. This innovation has the potential to transform diabetes management, providing a more accurate and pain-free alternative to current methods.
A nationwide study published in the Journal of the American Heart Association found that women with diabetes who are exposed to air pollution for long periods may have a much higher risk for heart disease. The study showed that cardiovascular disease and stroke risks increased by up to 66% among these individuals.
A new study using 3-D MRI found that diabetic patients have a higher risk of stroke due to advanced vascular disease, with 23.3% having intraplaque hemorrhage in at least one carotid artery. The finding suggests that 3-D MRI could be useful in determining stroke risk among diabetics.
Eating a daily handful of walnuts improves blood vessel cell wall function and lowers total and LDL cholesterol in adults at risk of diabetes. The walnut diet also enhances endothelial cell function, regardless of calorie intake.
A significant reduction in diabetes-related amputations has been observed since the mid-1990s, primarily due to advancements in diabetes care. The study found a 10-15% annual decrease in below-ankle and below-knee amputations among diabetic patients.
A pilot study has demonstrated that a mechanical artificial pancreas can better maintain normal blood glucose levels than multiple daily insulin injections in patients with pancreatitis. The treatment combines an AI-powered pump with islet cell transplantation, enabling the transplanted cells to survive longer and produce more insulin.
A nationwide study in Mexico found that diabetes incidence doubled every 10 years from 1960 to 2012, and up to 23% of the population could be diagnosed with the disease by 2050. The study highlights the need for comprehensive prevention strategies to reverse trends.
Researchers at UC Santa Barbara have developed an insulin pill using novel drug delivery technology that shows early promise as a form of diabetes therapy. The pill's oral delivery system could circumvent the discomfort associated with injections, leading to improved patient compliance and potentially more effective treatment.
Researchers at the University of California, San Diego have made significant breakthroughs in understanding how fat cells metabolize nutrients to produce fatty acids. This discovery could lead to new insights into potential irregularities in fat cell metabolism and help identify better drug targets for treating diabetes and obesity.
Researchers tested intensive multifaceted interventions to reduce Potentially Inappropriate Prescribing (PIP) in older patients, finding significant reductions in PIP. A systematic review also found transitional care interventions for congestive heart failure patients reduced readmission and emergency department visits. Additionally, m...
A new study found that promptly diagnosing and treating diabetes in heart attack patients significantly improves their cardiac outcomes. Researchers identified 707 patients who met criteria for a diabetes diagnosis but were only clinically diagnosed 30% of the time.
A Japanese study found that bus/train commuters were 44% less likely to be overweight, 27% less likely to have high blood pressure, and 34% less likely to have diabetes compared to drivers. Regular public transportation use may also encourage longer walks to and from the train or bus station.
New equations predict lifetime risk of kidney failure in living kidney donors, with those developing diabetes or hypertension facing higher risks. The findings highlight the need for revised kidney transplant policies and emphasize the importance of monitoring donor health.
Researchers found pregnant women with depression symptoms spend more time sitting down, leading to greater weight gain and higher risk of gestational diabetes. Reducing sitting time may improve metabolic health during pregnancy.
Researchers investigated how hypoglycemia affects cardiovascular autonomic control, finding a clear change in the body's responses to cardiovascular stress. The study suggests that hypoglycemia may compromise the heart's function.