Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
A collaborative meta-analysis found that creatinine-based eGFR and albuminuria improve cardiovascular prediction, particularly for mortality and heart failure. The assessment of albumin-to-creatinine ratio (ACR) outperformed traditional risk factors, suggesting its potential broad implications for cardiovascular risk classification.
A study published in JAMA Ophthalmology found that patients taking metformin hydrochloride had a 25% reduced risk of developing open-angle glaucoma compared to those who took no metformin. Higher doses of metformin were associated with greater reductions in OAG risk, suggesting potential benefits for eye health.
A study published in BMC Family Practice reveals that South Asian individuals with diabetes often struggle due to conflicting views on the causes of their condition. However, strong family support networks can help manage the disease, highlighting the need for culturally sensitive treatment plans and education guidelines.
A four-year study of 73,357 Chinese adults found that faster heart rates were positively associated with an increased risk of developing diabetes. Participants with faster heart rates had a 23% increased risk of diabetes for every 10 beats per minute, similar to the effects of a 3 kilogram per meter square increase in body mass index.
A new study published in The Lancet reveals that ACE inhibitors and angiotensin-receptor blockers (ARBs) are the most effective treatments for preventing end-stage kidney disease in adults with diabetes. These medications, used alone or in combination, have been shown to protect kidney function in the long term.
Associate Professor Suetonia Palmer's study provides an evidence-based guide on safe and effective blood-pressure-lowering drugs for patients with kidney disease and diabetes. The research, published in the Lancet journal, compared hundreds of studies to identify the most effective treatments.
People with metabolic syndrome face a higher risk of cardiovascular death than those without the condition. The study found that having diabetes or high blood pressure significantly elevates this risk. Women with metabolic syndrome were also at a greater risk of death from any cause compared to their male counterparts.
A new study suggests that widespread diabetes screening in India using current methods could lead to massive waste of resources and unnecessary testing. The researchers estimate that only between 26 million and 37 million out of 567 million eligible individuals would meet the international diagnostic criteria for diabetes.
A new study finds that shift workers are more likely to be overweight and experience sleep problems, increasing the risk of metabolic disorders like diabetes. Sufficient sleep may partially alleviate these adverse health effects.
MIT researchers found that larger spherical devices are better able to maintain their function and avoid scar-tissue buildup, outperforming smaller ones in tests on diabetic mice and nonhuman primates. This discovery could lead to the development of long-term implants for diabetes treatment and other diseases.
A growing number of people will be overweight or obese by 2030, with significant health and economic consequences. The UK's obesity problem requires a multi-disciplinary approach, combining scientific research, environmental factors, personal behavior, and policy interventions.
A new study suggests a diabetes drug may prevent cardiovascular problems in HIV-positive adults by reducing inflammation linked to heart disease and stroke. The drug, sitagliptin, improved metabolism and reduced inflammation in HIV patients taking antiretroviral therapy.
Recent studies on artificial pancreas systems have identified security vulnerabilities, including software integrity and malware threats. The authors propose a more formal approach to reporting the technical characteristics of these complex systems to ensure their safety.
A large study of Tricare patients found that statin users were 87% more likely to develop diabetes and had a higher risk of complications. The study confirms past findings on the link between statins and diabetes risk, but is among the first to show this connection in a relatively healthy population.
A disease-specific employee-based health plan can improve medication adherence by almost five percent, translating to a one percent reduction in healthcare spending. The plan also reduces hospital visits and emergency treatment centers.
Researchers found that chronic high blood sugar disrupts mitochondria activity by altering levels of O-GlcNAc transferase and removal enzymes. This leads to less efficient energy production, increased heat and damaging molecules, and further elevates blood sugar.
A new study found that adding two minutes of walking each hour can help offset the health risks associated with prolonged sitting. The research suggests that even light activities like casual walking or gardening can provide significant health benefits and potentially increase life expectancy.
A recent UCLA study found that only 3.7% of US adults with pre-diabetes were prescribed metformin, despite its proven effectiveness. The study highlights the underuse of metformin for diabetes prevention, which could be attributed to lack of knowledge and reluctance by patients and doctors.
A church-based education program led by trained community members helped Latino adults with diabetes adopt healthier lifestyles, including reduced high-fat food consumption and increased exercise. Participants reported significant improvements six months after the program concluded.
A new study found that using a simple device for eight hours a night can help people with prediabetes improve their blood sugar levels and reduce the risk of progressing to diabetes. Continuous positive airway pressure (CPAP) treatment was shown to lower glucose metabolism, insulin regulation, stress hormone levels, and blood pressure.
A study found that FOXO1, a protein promoting tissue repair, acts as an inhibitor of wound healing in diabetes patients. High glucose levels slow keratinocyte migration, while insulin speeds up the process. The research suggests inhibiting FOXO1 could speed healing in diabetic patients.
Experts in British Journal of Sports Medicine say regular exercise is key to staving off serious disease, but calorie-laden diets generate more ill health than physical inactivity. The evidence suggests up to 40% of those within a normal weight range harbor harmful metabolic abnormalities.
Researchers found differing perceptions among adults at-risk for diabetes based on individual risk factors, including age, ethnicity, and BMI. These findings suggest tailoring diabetes education and outreach to an individual's perceptions can maximize self-care behaviors and reduce adverse outcomes.
The Sugar app, developed at Worcester Polytechnic Institute, is entering a pilot clinical study to assess its effectiveness in managing diabetes. The app tracks blood sugar levels, weight, exercise, and wound care, providing patients with personalized messages and insights.
An observational study of San Antonio men and women aged 65+ found that frequent diet soda consumption was associated with significant increases in waist circumference over 9 years. The risk of metabolic disease, diabetes, heart attack, stroke, cancer, and mortality also rose proportionally.
Exposure to BPA during pregnancy may raise a mother's susceptibility to weight gain and diabetes later in life. The study found that BPA can harm glucose metabolism in offspring exposed in utero, leading to an increased predisposition to developing metabolic syndrome or diabetes.
A new study found that night owls are more likely to develop diabetes, metabolic syndrome, and sarcopenia than early risers. Night owls tend to have poorer sleep quality and engage in unhealthy behaviors like smoking and late-night eating.
A research team has isolated energy-burning beige fat from adult humans, which can convert unhealthy white fat into healthy brown fat. This discovery holds promise for developing new medications to fight obesity by recruiting and activating human brown fat.
A new study found that medication for type II diabetes activates sensors on brain cells, increasing hunger and leading to weight gain. Researchers at Georgia State University discovered the role of peroxisome proliferator-activated receptor Upsih (PPAR&Upsih) sensors in controlling eating behavior.
Researchers developed a global model to predict CVD risk, analyzing data from over 50,000 participants. The model estimates fatal CVD risk over 10 years for 11 countries, highlighting disparities in high-risk populations between low- and middle-income countries.
A new study by Women's College Hospital found that women with diabetes are more likely to be diagnosed with advanced stage breast cancer. The study analyzed data from over 38,000 women and found that those with diabetes were 14% more likely to present with Stage II or III breast cancer.
A study published by NYU Langone researchers found that patients with diabetes who undergo ankle fracture surgery have significantly longer lengths of stay and total hospital charges compared to non-diabetics. Patients with complicated disease also experience worse trends, with increased costs and prolonged hospital stays.
Researchers from the University of Copenhagen have developed a secure way to measure the protein apo-M, which may hold clues to diseases such as multiple sclerosis, arteriosclerosis, and diabetes. The new method uses commercially available antibodies to unfold the protein's complex structure, making it easier to identify.
A Johns Hopkins study reveals that drug companies have extended patents on insulin for over 90 years, preventing generic versions from entering the market. This has led to costly treatment options, with prices ranging from $120 to $400 per month, and hospitalizations due to uncontrolled diabetes.
Research suggests that too much artificial light in the evening can disrupt the body's circadian rhythm and lead to health problems such as breast cancer, obesity, diabetes, and depression. Experts recommend using devices with dimmer, longer wavelengths of light in the evening to minimize disruption.
Researchers at Henry Ford Health discovered that sildenafil improves neurological function even in middle-aged mice with long-term diabetic peripheral neuropathy. The study suggests new insights into underlying mechanisms and potential treatment for long-term diabetic neuropathy.
A new study suggests that eating a high-caloric breakfast and a more modest dinner can significantly reduce post-meal glucose surges and improve glycemic control in type-2 diabetics. By consuming a larger meal at breakfast and a smaller meal at dinner, participants experienced lower blood glucose levels and increased insulin sensitivity.
A new study of adult daughters found that women whose parents smoked during pregnancy had an increased risk of developing diabetes mellitus. Prenatal environmental tobacco smoke exposure appears to be a modifiable risk factor for diabetes in offspring.
A new study found that onion extract can strongly lower high blood glucose levels and total cholesterol in diabetic rats when given with the antidiabetic drug metformin. The extract also showed potential for use in treating patients with diabetes.
A workplace lifestyle intervention program developed by the University of Pittsburgh significantly reduces risk factors for diabetes and heart disease. Participants lost an average of 5% of their body weight and increased physical activity, with 96% saying it was beneficial to offer the program.
Columbia University researchers successfully converted human skin cells into hypothalamic neurons, a type that regulates appetite. These neurons provide a patient-specific model for studying the neurophysiology of weight control and testing potential therapies.
A new NYU study successfully screens for diabetes using oral blood at dental visits, finding a 99% correlation with finger stick tests. The study's principal investigator believes dental visits could be an opportune site for diabetes screening among at-risk patients.
Research suggests that heart failure patients who struggle with daily activities are at a higher risk of hospitalization and early death. The study found that older women, unmarried individuals, and those with chronic conditions such as obesity, dementia, anemia, and diabetes were more likely to experience these negative outcomes.
Pregnant women after bariatric surgery are at higher risk for complications like preterm birth and small babies, but lower risk of gestational diabetes. Maternal health services should provide extra care to these women.
A study found that nearly half of patients with mental illness and a third of those with diabetes were not advised on dietary changes or physical activity. Health care providers may be missing opportunities to counsel high-risk patients about lifestyle modifications.
A new review finds that people with mild cognitive impairment are 65% more likely to develop dementia if they have diabetes and over twice as likely if they have psychiatric symptoms. Lifestyle changes such as a healthy diet and regular exercise may help prevent dementia.
Researchers developed a model to predict who stands to gain most from diabetes-preventing drugs or lifestyle changes like exercise and weight loss. The model identified seven key factors: fasting blood sugar, A1C level, triglycerides, family history of high blood sugar, waist measurement, height, and waist-to-hip ratio.
Non-alcoholic fatty liver disease (NAFLD) affects 25% of adults in the US, with excessive fat building up in liver cells. Researchers at BMC will investigate molecular mechanisms and identify novel treatments for NAFLD using retinoic acid and its nuclear receptor.
Research presented at the Saudi Heart Association conference reveals that 26% of participants are at high risk of having a heart attack or dying from a heart attack in 10 years. The study found that diabetes, obesity, and smoking were major contributors to this risk.
A 20-year study found that South Asian men have higher levels of tyrosine and several other amino acids associated with increased diabetes risk. Tyrosine was a stronger predictor of incident diabetes in South Asians, even after adjusting for obesity and insulin resistance.
A study published by UC Davis and Public Health Institute found that children exposed to tobacco smoke in utero are two to three times more likely to develop diabetes as adults. Birth weight did not affect the risk of developing diabetes.
A study of 115,538 older patients with diabetes found that geriatric conditions were more common than diabetic complications, but their prevalence varied little by ethnicity. The research suggests that culturally competent care is essential for addressing disparities in this population.
Research from WashU suggests that poverty and inactivity are linked to diabetes prevalence, but only in certain areas. Localized approaches can target the most common predictors of diabetes in each region.
A newly discovered protein called HKDC1 may be a genetic predictor for gestational hyperglycemia and its long-term health effects. The enzyme appears during pregnancy in women with less of the gene, which could lead to a predictive test and potential therapeutic targets.
Researchers at Stanford University School of Medicine identified limostatin, a hormone that decreases insulin levels during recovery from fasting or starvation, in fruit flies and found a similar protein in humans. This discovery has critical ramifications for understanding metabolism and may inform new efforts to combat diabetes.
The study, following 300 young people from age five since 2000, aims to test whether patterns of pancreatic function detected in childhood persist into adulthood. It will also explore the childhood origins of a range of new health problems, including dental and psychological health issues.
Researchers at Cornell University engineered a probiotic to secrete GLP-1, reducing high blood glucose by up to 30% in diabetic rats. The treatment mimics the function of pancreatic beta cells, shifting glucose control from the pancreas to the upper intestine.
A new study found that middle-aged heavy drinkers (more than two drinks daily) had a 34% higher risk of stroke compared to light drinkers. Heavy drinking also increased stroke risk in mid-life, regardless of genetic and early-life factors.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that women diagnosed with polycystic ovary syndrome (PCOS) are twice as likely to be hospitalized for reasons unrelated to reproductive health or injury. The study, which examined health records of over 2,500 women with PCOS, also foun...
Researchers at Penn Dental Medicine have identified Foxo1 as a critical molecule that impairs wound healing in diabetics. The study found that deleting Foxo1 in keratinocytes improved wound healing in diabetic mice, suggesting a potential target for therapies to boost healing.