Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
Researchers at Georgia State University have been awarded a $2.4 million grant from the National Institutes of Health to study the impact of diabetes on cardiovascular health. The team aims to develop new therapies targeting damaged mitochondria to prevent or delay Type 2 diabetes.
Research links combat injuries to increased risk of high blood pressure, diabetes, and kidney disease in US veterans. The more severe the injury, the higher the risk of developing these conditions due to inflammation and other factors.
Researchers at UCSF and Feeding America found that providing nutritious food and education to low-income individuals with diabetes improved glycemic control and medication adherence. The intervention also encouraged the consumption of healthy foods, including fruits and vegetables.
A panel of markers has been discovered that can identify pre-diabetes by measuring fatty acids in blood, allowing for early warning and lifestyle change. The levels of these fatty acids can change up to 10 years before diagnosis, making it a potential tool for predicting the risk of developing pre-diabetes and metabolic syndrome.
A large meta-analysis of over 68,000 adults found that low-fat diets do not lead to greater weight loss in the long term compared to higher-fat diets. The analysis suggests that alternative diets like low-carb or Mediterranean diets may be more effective for achieving long-term weight loss.
A pharmacy-led glycemic control program is linked to improved outcomes for surgical patients with diabetes, including fewer complications and readmissions. Patients in the program had better blood sugar control, reduced hospital readmissions, and lower medical costs.
The age-standardized death rate for all causes combined decreased by 43% between 1969 and 2013, driven by declines in heart disease, cancer, stroke, and unintentional injuries. While the rate of decrease has slowed for these leading causes, other factors such as tobacco control efforts and advances in early detection and treatment have...
Researchers have developed an intestinal patch device containing insulin that can be swallowed as a capsule, demonstrating efficacy in managing blood glucose levels in diabetic rats. The patches showed excellent mucoadhesive strength and released insulin within five hours, reducing blood glucose levels significantly.
Only 27% of older patients with diabetes underwent medication deintensification due to very low hemoglobin A1c levels or blood pressure values. Treatment was deintensified in 16% of those with moderately low and 18.8% of those with very low blood pressure levels. The study suggests that medication deintensification is underutilized, pa...
Researchers at Yale University have developed a synthetic process to synthesize glucosepane, a critical chemical link in both diabetes and aging. This breakthrough may lead to the development of tools to examine the role glucosepane plays in human health and potentially inhibit its formation.
A new synthesis method for glucosepane, a molecule implicated in diseases such as diabetes, has been developed by researchers. This breakthrough allows for the production of glucosepane's various forms, which may help uncover its role in health complications and potential countermeasures.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that mothers with gestational diabetes have slower-firing brains in their unborn children. This may be due to the mother's metabolism influencing her child's development and increasing their risk of obesity and diabetes later in life.
A new study found that elevated blood sugar levels in pregnancy are linked to an increased risk of congenital heart defects, including tetralogy of Fallot and dextrotransposition of the great arteries. High glucose levels were correlated with an increased risk of tetralogy of Fallot, but not dextrotransposition of the great arteries.
The New Jersey Innovation Institute will work with thousands of medical practices to implement a value-based care system, compensating caregivers for keeping patients well through ongoing disease management. The program aims to reduce hospital readmissions and improve health outcomes for patients with complex conditions such as diabete...
A new study found that severely obese children are more likely to develop heart disease and diabetes, with the risk increasing as obesity severity increases. The study suggests that implementing a more complex classification system could help target interventions and treatments for these high-risk children.
A new study found no significant differences in self-care activities and diabetes test results between patients of nurse prescribers and non-prescribers. Despite the benefits of prescribing qualification, budget concerns may lead primary care practices to invest in lower-paid nurses.
A new study by researchers at St. Michael's Hospital found that patients in Ontario who received primary care from a family health team had improved diabetes care, including increased monitoring and management. However, the impact on cancer screening was mixed, with some areas showing improvement while others did not.
A study based on over 10 million patients found that family health teams led to improved diabetes monitoring and screening rates. Patients in these teams were more likely to receive recommended testing and screenings for breast cancer and colorectal cancer.
A retrospective follow-up study found that diabetic women are more at risk of cardiovascular events such as heart attacks, ischemic strokes, and congestive heart failure. The risk is highest for women after menopause, with a significant gender-driven 'risk window' for those aged 45 years and over.
A systematic review and meta-analysis of 11 million patients found that diabetic women are 40% more likely to suffer acute coronary syndromes than diabetic men. The study highlights the need for comprehensive risk control and early diagnosis in female patients with diabetes.
A new study from the UNC School of Medicine reveals that a diabetes drug called rosiglitazone substantially increases bone fat, leading to an increased risk of bone fractures. However, exercise has been shown to decrease bone fat by around 10%, which can help mitigate this risk.
A new study found that people with health insurance are more likely to have their chronic conditions correctly diagnosed and under control. If half of nonelderly uninsured Americans gain health insurance, an estimated 1.5 million newly insured individuals will be diagnosed with one or more conditions.
A new study found that a commonly used diabetes treatment provides protection against terminal blood loss. Researchers identified how the medication works at a cellular level to prevent shock and death from massive blood loss.
A new analysis of the TECOS study adds heart failure data to confirm sitagliptin's cardiovascular safety. The findings provide reassurance to patients and prescribers about the drug's risk profile.
A recent study presented at ESC Congress found that young women with diabetes have a six-fold risk of heart attack. The research, which analyzed data from over 7,000 women, also revealed that smoking was the leading risk factor for young women with myocardial infarction.
Researchers found that ezetimibe, when added to a statin, significantly reduced the risk of future ischemic stroke, heart attack, and cardiovascular death in patients with diabetes who had an acute coronary syndrome. Ezetimibe also lowered LDL-cholesterol levels by 43mg/dL after one year.
A subgroup analysis of the IMPROVE-IT trial found that ezetimibe significantly reduced the chances of future major cardiac or vascular events in patients with diabetes by 14% compared to placebo. Ezetimibe added to a statin lowered LDL cholesterol at 1 year, resulting in lower risks of cardiovascular events.
Research found that depressed patients with high or low blood pressure had the highest risk of major vascular events, including stroke or heart attack, at four years. The study included 35,537 patients and showed that depressive symptoms interacted with blood pressure to predict these outcomes.
A study of over 55,000 CABG patients found diabetics had more postoperative complications and decreased long-term survival. The proportion of diabetic patients undergoing CABG increased 5-fold between 1970-2010, driven by higher costs and clinical risks.
A University of Kansas study reveals that physical activity is more beneficial for preventing and managing diabetes among college graduates than those with less education. Adults with a college degree who are physically active were 6% less likely to have pre-diabetic symptoms.
A new study reveals liver fibrosis affects 5.6% of adults aged ?45, primarily those with diabetes or steatosis. The rising prevalence highlights the growing concern of liver health issues due to an aging population and increasing rates of diabetes and obesity.
Babies diagnosed with diabetes are now immediately tested for all 22 genetic causes, reducing referral time from over four years to under two months. This early comprehensive gene testing provides accurate information on clinical features that haven't yet developed, enabling doctors to anticipate and prevent medical problems.
A study by researchers at the University of Edinburgh found that smoking bans led to a 8% drop in stillbirths and newborn deaths in England, resulting in 1500 avoided deaths. The ban also reduced low birth weight cases by over 5000.
Researchers at the University of Otago discovered that a normal cell process called autophagy is deregulated in diabetic hearts, leading to progressive loss of cardiac cells and cardiac dysfunction. Targeting the Beclin-1 protein presents an promising avenue for new treatments of diabetes-related cardiac disease.
Researchers found that high blood sugar molecules can weaken the body's natural defenses against infections. Dicarbonyls, breakdown products of glucose, interfere with antimicrobial peptides that fight inflammation and infection. This discovery could contribute to developing new treatments for people with uncontrolled diabetes.
A randomized controlled trial found that individualized lifestyle counseling reduced gestational diabetes incidence in high-risk pregnant women. The study showed a significant reduction in GDM diagnosis and improved health outcomes for both mothers and children.
A clinical trial found that telephone counseling led to significant A1c level reductions among participants with extremely elevated levels. The intervention resulted in an average decrease of 2.1 percentage points, compared to a 1.3 percentage point decrease for those receiving printed self-management materials only.
Research found that people with diabetes taking glitazone medications had a 28% lower risk of developing Parkinson's disease. The study, conducted by London School of Hygiene & Tropical Medicine researchers, also found that current users of the medication experienced a significant reduction in PD risk.
A new study published in PLOS Medicine suggests that taking diabetes medication glitazones may lower the risk of developing Parkinson's disease by 28%. Researchers analyzed data from over 160,000 diabetes patients and found a significant association between glitazone use and reduced incidence of Parkinson's.
Researchers found that many older Americans with diabetes are not meeting clinical targets for blood sugar, cholesterol, and blood pressure levels. Despite using less stringent guidelines, the study revealed significant racial disparities in diabetes control, particularly among women.
A recent study published in The Lancet Diabetes and Endocrinology found that treating obese pregnant women with the diabetes drug metformin does not reduce their babies' birth weights. Despite this, the treatment did help lower blood sugar levels in mothers-to-be and markers linked to pre-eclampsia and premature births.
A large-scale trial found that an intensive diet and exercise regime does not prevent gestational diabetes in obese pregnant women. However, the intervention led to reductions in pregnancy weight gain, lower glycaemic load, and higher activity levels, which were associated with healthier outcomes for mothers and children.
A nationwide study found that people with diabetes and high rates of complications are more likely to develop dementia as they age. Better blood sugar control is crucial for preventing the onset of dementia.
A new study analyzing over 135,000 deaths found that individuals with both diabetes and heart disease have substantially lower life expectancy compared to those with one or no condition. Men with two cardiometabolic conditions had an average reduction in life expectancy of 12-23 years at age 40, while women had a 20-year reduction.
A study analyzing nearly 1.2 million participants found that mortality rates are similar for each condition, but risk increases substantially with additional conditions. Patients with multiple cardiometabolic conditions can experience significant reductions in life expectancy, up to 15 years lower at age 60.
The project aims to improve food environments and increase physical activity in southwest Atlanta's target neighborhoods. Over three years, it will work to increase healthy food access for at least 75% of the communities.
A study found that a small group of authors, including those employed by pharmaceutical companies, dominated diabetes research with an over-reliance on commercially sponsored studies. This raises concerns about the balance of power and conflict of interest in the field.
A recent study published in Circulation estimates that sugary drink consumption is responsible for approximately 133,000 deaths from diabetes, 45,000 deaths from cardiovascular disease, and 6,450 deaths from cancer annually. Reducing sugar-sweetened beverage consumption could save tens of thousands of lives worldwide.
Researchers have evaluated the best potential sources for adult stem cells to be used for treating diabetic retinopathy. They found that cells taken from donors without diabetes are more effective than those from patients' own bodies. This discovery provides a crucial framework for evaluating stem cells for future treatments.
Scientists have identified a gatekeeper enzyme that prevents cell death in Wolfram syndrome, a rare form of diabetes. Replacing or enhancing the enzyme strengthens cellular membranes and stops molecules from leaking into other parts of the cell.
Diabetic neuropathy, a condition affecting up to 60% of diabetes patients, can be reversed by stem cell injections that promote angiogenesis and nerve re-myelination. Researchers have identified new mechanisms by which mesenchymal stem cells can improve the condition.
A recent study found that the new NICE thresholds for diagnosing gestational diabetes in pregnancy are less effective than international criteria, potentially missing thousands of women at high risk. The research suggests that using the WHO guidelines could identify an additional 3,000 to 4,000 women each year in the UK.
A Phase II clinical trial presented promising results for baricitinib in people with diabetic kidney disease, reducing a key sign of kidney damage and inflammation. The trial's success demonstrates the potential of precision medicine in treating this common yet devastating condition affecting millions of Americans.
A recent study by the American Diabetes Association found that Latinos experiencing food insecurity have poorer glycemic control and eat fewer vegetables. The study suggests that food insecurity should be considered in overall diabetes management, highlighting the need for individualized care.
Studies by Scripps Whittier Diabetes Institute found that poorly controlled blood sugar levels result in significantly longer and more expensive hospital stays. Care teams focused on managing diabetes during hospitalization can improve patient outcomes and reduce costs.
Nonfatal diseases and injuries are increasingly affecting global health, with back pain, depression, and mental disorders among the leading causes of years lived with disability. The study found that YLDs increased by 52% between 1990 and 2013, with population growth and aging contributing to the growing burden.
A major new analysis from the Global Burden of Disease Study 2013 reveals that nearly 20 people in 100 worldwide had no health problems in 2013. Over 2.3 billion individuals experienced more than five ailments, with low back pain and depression ranking as top contributors to disability.
The American Diabetes Association, American Association of Diabetes Educators, and the Academy of Nutrition and Dietetics have released a joint position statement outlining when and how to deliver diabetes self-management education and support (DSME/S) to patients. The guidelines highlight four critical life junctures: diagnosis, annua...
In silico experiments show that more accurate continuous glucose monitoring (CGM) systems can detect dangerously low blood sugar and reduce the frequency of hypoglycemic episodes. The technology improves glycemic control by providing more precise measurements, enabling better decision-making for individuals with diabetes.
The National Institutes of Health has awarded a $10.5 million grant to the Einstein-Mount Sinai Diabetes Research Center, which aims to expand ongoing diabetes research projects, initiate new studies, and improve service delivery in the New York metropolitan area.