Articles tagged with Diabetes
A study by researchers at the University of Edinburgh found that smoking bans led to a 8% drop in stillbirths and newborn deaths in England, resulting in 1500 avoided deaths. The ban also reduced low birth weight cases by over 5000.
Researchers at the University of Otago discovered that a normal cell process called autophagy is deregulated in diabetic hearts, leading to progressive loss of cardiac cells and cardiac dysfunction. Targeting the Beclin-1 protein presents an promising avenue for new treatments of diabetes-related cardiac disease.
Researchers found that high blood sugar molecules can weaken the body's natural defenses against infections. Dicarbonyls, breakdown products of glucose, interfere with antimicrobial peptides that fight inflammation and infection. This discovery could contribute to developing new treatments for people with uncontrolled diabetes.
A randomized controlled trial found that individualized lifestyle counseling reduced gestational diabetes incidence in high-risk pregnant women. The study showed a significant reduction in GDM diagnosis and improved health outcomes for both mothers and children.
A clinical trial found that telephone counseling led to significant A1c level reductions among participants with extremely elevated levels. The intervention resulted in an average decrease of 2.1 percentage points, compared to a 1.3 percentage point decrease for those receiving printed self-management materials only.
A new study published in PLOS Medicine suggests that taking diabetes medication glitazones may lower the risk of developing Parkinson's disease by 28%. Researchers analyzed data from over 160,000 diabetes patients and found a significant association between glitazone use and reduced incidence of Parkinson's.
Researchers found that many older Americans with diabetes are not meeting clinical targets for blood sugar, cholesterol, and blood pressure levels. Despite using less stringent guidelines, the study revealed significant racial disparities in diabetes control, particularly among women.
Research found that people with diabetes taking glitazone medications had a 28% lower risk of developing Parkinson's disease. The study, conducted by London School of Hygiene & Tropical Medicine researchers, also found that current users of the medication experienced a significant reduction in PD risk.
A recent study published in The Lancet Diabetes and Endocrinology found that treating obese pregnant women with the diabetes drug metformin does not reduce their babies' birth weights. Despite this, the treatment did help lower blood sugar levels in mothers-to-be and markers linked to pre-eclampsia and premature births.
A large-scale trial found that an intensive diet and exercise regime does not prevent gestational diabetes in obese pregnant women. However, the intervention led to reductions in pregnancy weight gain, lower glycaemic load, and higher activity levels, which were associated with healthier outcomes for mothers and children.
A nationwide study found that people with diabetes and high rates of complications are more likely to develop dementia as they age. Better blood sugar control is crucial for preventing the onset of dementia.
A study analyzing nearly 1.2 million participants found that mortality rates are similar for each condition, but risk increases substantially with additional conditions. Patients with multiple cardiometabolic conditions can experience significant reductions in life expectancy, up to 15 years lower at age 60.
A new study analyzing over 135,000 deaths found that individuals with both diabetes and heart disease have substantially lower life expectancy compared to those with one or no condition. Men with two cardiometabolic conditions had an average reduction in life expectancy of 12-23 years at age 40, while women had a 20-year reduction.
The project aims to improve food environments and increase physical activity in southwest Atlanta's target neighborhoods. Over three years, it will work to increase healthy food access for at least 75% of the communities.
A study found that a small group of authors, including those employed by pharmaceutical companies, dominated diabetes research with an over-reliance on commercially sponsored studies. This raises concerns about the balance of power and conflict of interest in the field.
A recent study published in Circulation estimates that sugary drink consumption is responsible for approximately 133,000 deaths from diabetes, 45,000 deaths from cardiovascular disease, and 6,450 deaths from cancer annually. Reducing sugar-sweetened beverage consumption could save tens of thousands of lives worldwide.
Researchers have evaluated the best potential sources for adult stem cells to be used for treating diabetic retinopathy. They found that cells taken from donors without diabetes are more effective than those from patients' own bodies. This discovery provides a crucial framework for evaluating stem cells for future treatments.
Diabetic neuropathy, a condition affecting up to 60% of diabetes patients, can be reversed by stem cell injections that promote angiogenesis and nerve re-myelination. Researchers have identified new mechanisms by which mesenchymal stem cells can improve the condition.
Scientists have identified a gatekeeper enzyme that prevents cell death in Wolfram syndrome, a rare form of diabetes. Replacing or enhancing the enzyme strengthens cellular membranes and stops molecules from leaking into other parts of the cell.
A recent study found that the new NICE thresholds for diagnosing gestational diabetes in pregnancy are less effective than international criteria, potentially missing thousands of women at high risk. The research suggests that using the WHO guidelines could identify an additional 3,000 to 4,000 women each year in the UK.
A Phase II clinical trial presented promising results for baricitinib in people with diabetic kidney disease, reducing a key sign of kidney damage and inflammation. The trial's success demonstrates the potential of precision medicine in treating this common yet devastating condition affecting millions of Americans.
A recent study by the American Diabetes Association found that Latinos experiencing food insecurity have poorer glycemic control and eat fewer vegetables. The study suggests that food insecurity should be considered in overall diabetes management, highlighting the need for individualized care.
A major new analysis from the Global Burden of Disease Study 2013 reveals that nearly 20 people in 100 worldwide had no health problems in 2013. Over 2.3 billion individuals experienced more than five ailments, with low back pain and depression ranking as top contributors to disability.
Studies by Scripps Whittier Diabetes Institute found that poorly controlled blood sugar levels result in significantly longer and more expensive hospital stays. Care teams focused on managing diabetes during hospitalization can improve patient outcomes and reduce costs.
Nonfatal diseases and injuries are increasingly affecting global health, with back pain, depression, and mental disorders among the leading causes of years lived with disability. The study found that YLDs increased by 52% between 1990 and 2013, with population growth and aging contributing to the growing burden.
The American Diabetes Association, American Association of Diabetes Educators, and the Academy of Nutrition and Dietetics have released a joint position statement outlining when and how to deliver diabetes self-management education and support (DSME/S) to patients. The guidelines highlight four critical life junctures: diagnosis, annua...
In silico experiments show that more accurate continuous glucose monitoring (CGM) systems can detect dangerously low blood sugar and reduce the frequency of hypoglycemic episodes. The technology improves glycemic control by providing more precise measurements, enabling better decision-making for individuals with diabetes.
The National Institutes of Health has awarded a $10.5 million grant to the Einstein-Mount Sinai Diabetes Research Center, which aims to expand ongoing diabetes research projects, initiate new studies, and improve service delivery in the New York metropolitan area.
A collaborative meta-analysis found that creatinine-based eGFR and albuminuria improve cardiovascular prediction, particularly for mortality and heart failure. The assessment of albumin-to-creatinine ratio (ACR) outperformed traditional risk factors, suggesting its potential broad implications for cardiovascular risk classification.
A study published in JAMA Ophthalmology found that patients taking metformin hydrochloride had a 25% reduced risk of developing open-angle glaucoma compared to those who took no metformin. Higher doses of metformin were associated with greater reductions in OAG risk, suggesting potential benefits for eye health.
A study published in BMC Family Practice reveals that South Asian individuals with diabetes often struggle due to conflicting views on the causes of their condition. However, strong family support networks can help manage the disease, highlighting the need for culturally sensitive treatment plans and education guidelines.
A four-year study of 73,357 Chinese adults found that faster heart rates were positively associated with an increased risk of developing diabetes. Participants with faster heart rates had a 23% increased risk of diabetes for every 10 beats per minute, similar to the effects of a 3 kilogram per meter square increase in body mass index.
Associate Professor Suetonia Palmer's study provides an evidence-based guide on safe and effective blood-pressure-lowering drugs for patients with kidney disease and diabetes. The research, published in the Lancet journal, compared hundreds of studies to identify the most effective treatments.
A new study published in The Lancet reveals that ACE inhibitors and angiotensin-receptor blockers (ARBs) are the most effective treatments for preventing end-stage kidney disease in adults with diabetes. These medications, used alone or in combination, have been shown to protect kidney function in the long term.
People with metabolic syndrome face a higher risk of cardiovascular death than those without the condition. The study found that having diabetes or high blood pressure significantly elevates this risk. Women with metabolic syndrome were also at a greater risk of death from any cause compared to their male counterparts.
A new study suggests that widespread diabetes screening in India using current methods could lead to massive waste of resources and unnecessary testing. The researchers estimate that only between 26 million and 37 million out of 567 million eligible individuals would meet the international diagnostic criteria for diabetes.
A new study finds that shift workers are more likely to be overweight and experience sleep problems, increasing the risk of metabolic disorders like diabetes. Sufficient sleep may partially alleviate these adverse health effects.
MIT researchers found that larger spherical devices are better able to maintain their function and avoid scar-tissue buildup, outperforming smaller ones in tests on diabetic mice and nonhuman primates. This discovery could lead to the development of long-term implants for diabetes treatment and other diseases.
A growing number of people will be overweight or obese by 2030, with significant health and economic consequences. The UK's obesity problem requires a multi-disciplinary approach, combining scientific research, environmental factors, personal behavior, and policy interventions.
A new study suggests a diabetes drug may prevent cardiovascular problems in HIV-positive adults by reducing inflammation linked to heart disease and stroke. The drug, sitagliptin, improved metabolism and reduced inflammation in HIV patients taking antiretroviral therapy.
Recent studies on artificial pancreas systems have identified security vulnerabilities, including software integrity and malware threats. The authors propose a more formal approach to reporting the technical characteristics of these complex systems to ensure their safety.
A disease-specific employee-based health plan can improve medication adherence by almost five percent, translating to a one percent reduction in healthcare spending. The plan also reduces hospital visits and emergency treatment centers.
A large study of Tricare patients found that statin users were 87% more likely to develop diabetes and had a higher risk of complications. The study confirms past findings on the link between statins and diabetes risk, but is among the first to show this connection in a relatively healthy population.
Researchers found that chronic high blood sugar disrupts mitochondria activity by altering levels of O-GlcNAc transferase and removal enzymes. This leads to less efficient energy production, increased heat and damaging molecules, and further elevates blood sugar.
A new study found that adding two minutes of walking each hour can help offset the health risks associated with prolonged sitting. The research suggests that even light activities like casual walking or gardening can provide significant health benefits and potentially increase life expectancy.
A recent UCLA study found that only 3.7% of US adults with pre-diabetes were prescribed metformin, despite its proven effectiveness. The study highlights the underuse of metformin for diabetes prevention, which could be attributed to lack of knowledge and reluctance by patients and doctors.
A church-based education program led by trained community members helped Latino adults with diabetes adopt healthier lifestyles, including reduced high-fat food consumption and increased exercise. Participants reported significant improvements six months after the program concluded.
A study found that FOXO1, a protein promoting tissue repair, acts as an inhibitor of wound healing in diabetes patients. High glucose levels slow keratinocyte migration, while insulin speeds up the process. The research suggests inhibiting FOXO1 could speed healing in diabetic patients.
A new study found that using a simple device for eight hours a night can help people with prediabetes improve their blood sugar levels and reduce the risk of progressing to diabetes. Continuous positive airway pressure (CPAP) treatment was shown to lower glucose metabolism, insulin regulation, stress hormone levels, and blood pressure.
Experts in British Journal of Sports Medicine say regular exercise is key to staving off serious disease, but calorie-laden diets generate more ill health than physical inactivity. The evidence suggests up to 40% of those within a normal weight range harbor harmful metabolic abnormalities.
Researchers found differing perceptions among adults at-risk for diabetes based on individual risk factors, including age, ethnicity, and BMI. These findings suggest tailoring diabetes education and outreach to an individual's perceptions can maximize self-care behaviors and reduce adverse outcomes.
The Sugar app, developed at Worcester Polytechnic Institute, is entering a pilot clinical study to assess its effectiveness in managing diabetes. The app tracks blood sugar levels, weight, exercise, and wound care, providing patients with personalized messages and insights.
An observational study of San Antonio men and women aged 65+ found that frequent diet soda consumption was associated with significant increases in waist circumference over 9 years. The risk of metabolic disease, diabetes, heart attack, stroke, cancer, and mortality also rose proportionally.
A new study found that night owls are more likely to develop diabetes, metabolic syndrome, and sarcopenia than early risers. Night owls tend to have poorer sleep quality and engage in unhealthy behaviors like smoking and late-night eating.
Exposure to BPA during pregnancy may raise a mother's susceptibility to weight gain and diabetes later in life. The study found that BPA can harm glucose metabolism in offspring exposed in utero, leading to an increased predisposition to developing metabolic syndrome or diabetes.
A research team has isolated energy-burning beige fat from adult humans, which can convert unhealthy white fat into healthy brown fat. This discovery holds promise for developing new medications to fight obesity by recruiting and activating human brown fat.
Researchers developed a global model to predict CVD risk, analyzing data from over 50,000 participants. The model estimates fatal CVD risk over 10 years for 11 countries, highlighting disparities in high-risk populations between low- and middle-income countries.
A new study found that medication for type II diabetes activates sensors on brain cells, increasing hunger and leading to weight gain. Researchers at Georgia State University discovered the role of peroxisome proliferator-activated receptor Upsih (PPAR&Upsih) sensors in controlling eating behavior.
A study published by NYU Langone researchers found that patients with diabetes who undergo ankle fracture surgery have significantly longer lengths of stay and total hospital charges compared to non-diabetics. Patients with complicated disease also experience worse trends, with increased costs and prolonged hospital stays.
A new study by Women's College Hospital found that women with diabetes are more likely to be diagnosed with advanced stage breast cancer. The study analyzed data from over 38,000 women and found that those with diabetes were 14% more likely to present with Stage II or III breast cancer.