Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
Coogan will investigate the effects of air pollution on hypertension and diabetes incidence in African American women, using data from the Black Women's Health Study. The study aims to inform public policy on air quality regulation and provide insight into a novel pathway whereby air pollution causes cardiovascular events.
Vitamin E helps repair tears in plasma membranes that protect cells from outside forces. Daily consumption of vitamin E is crucial to maintain healthy muscles and prevent conditions like muscular dystrophy and diabetes.
Nonalcoholic steatohepatitis (NASH) is rapidly increasing in the U.S., mainly related to obesity and diabetes. Researchers found excellent post-transplantation survival rates among NASH patients, with one-year survival rates near 88%.
An interdisciplinary research team at WPI will develop an integrated application to track blood sugar levels, weight, and image analysis of lesions. The app aims to provide personalized feedback to encourage patients to make good decisions and improve outcomes.
Researchers at the University of Liverpool found that diabetic pregnant women experience weaker uterine contractions, increasing the risk of emergency caesarean births. Calcium levels in the uterus are also significantly reduced in these women, leading to poorly contracting muscles.
A recent study found that resting muscle sympathetic nerve activity (MSNA) is a significant independent predictor of weight-loss outcome in overweight or obese subjects. Successful weight losers demonstrated large increases in nerve activity following a carbohydrate test meal.
Researchers at Joslin Diabetes Center have identified two major molecular signaling pathways that regulate cell growth and division, hallmarks of cancer biology. The study provides new candidate targets for treating soft-tissue sarcomas, which can be controlled but not cured by current treatments.
A U-M study reveals Hemoglobin A1c test fails to identify children with diabetes, highlighting the need for improved nonfasting testing strategies. Researchers recommend using a nonfasting one-hour glucose challenge test or random glucose to identify children at risk of developing diabetes.
The Canadian Diabetes Association has partnered with Elsevier to publish the Canadian Journal of Diabetes, a peer-reviewed journal promoting knowledge sharing and advancing diabetes research. The partnership aims to enhance the journal's excellence through Elsevier's global reach and expertise in scientific publication.
The MU researchers developed a diabetes dashboard tool that provides easy access to patients' health information, reducing mouse clicks from 60 to three and improving accuracy. This tool helps doctors make informed decisions about treatments, enhancing patient care.
According to Northwestern University researchers, over 83% of men and 72% of women will be overweight or obese in 2020. The implications of not improving cardiovascular health by 20% could lead to a reversal of declining rates of sickness and death from cardiovascular disease.
A study published in Neurology found that people with a history of stroke or diabetes who received clot-busting drugs had better outcomes than those who did not. The use of these drugs can limit damage and disability due to blood clots, and current guidelines should not exclude individuals from receiving this therapy.
The COBRA trial found that cryoplasty post-dilation decreases the risk of in-stent restenosis by 26.5% compared to conventional balloon angioplasty in patients with diabetes. Researchers used a cryoplasty dilatation system that simultaneously dilates and cools the vessel wall, inducing smooth muscle cell apoptosis.
Dr. Richard A. McIndoe is leading a $7.5 million National Institute of Diabetes and Digestive and Kidney Diseases grant to support studies on diabetes affecting 8.3% of Americans. The Diabetic Complications Consortium shares data on complications like heart attack, stroke, vision loss, and kidney damage.
Researchers found that blocking arginase-2 activity prevents kidney failure in diabetic mice, offering a new therapeutic approach for diabetic nephropathy. The study also suggests that this inhibition may protect against albuminuria and cardiovascular problems.
A study published in Clinical Journal of the American Society of Nephrology found that hospitalized diabetic patients who experience acute kidney injury are at a higher risk of developing chronic kidney disease. The research followed 4,082 patients with diabetes over 10 years, revealing that multiple episodes of acute kidney injury inc...
Dr. Patrick Catalano received the March of Dimes Agnes Higgins Award for his research showing a link between maternal obesity and an increased risk of metabolic disorders in babies. His work highlights the importance of weight control early in pregnancy to protect children from chronic diseases.
A new five-year, $1 million grant enables Michigan State University to develop an intensive three-year residency curriculum focused on primary care mental health. The program aims to improve training for primary care physicians in caring for patients with mental health needs.
Dr. Clyde Yancy predicts that people who follow seven simple lifestyle factors can live an additional 40-50 years after age 50, with a 90% chance of living to 90 or 100 without chronic illnesses. Governments are urged to invest in prevention strategies.
A Mayo Clinic study of over 5,200 patients found no significant correlation between shockwave lithotripsy for kidney stones and the development of diabetes. Researchers controlled for age, gender, and obesity to rule out any potential link.
A study by researchers at the University of Chicago found that moving to lower-poverty neighborhoods decreases the risk of obesity and diabetes. The study collected data from 4,498 women and children who participated in a residential mobility program called Moving to Opportunity.
A new study found that low-income women with children who move from high-poverty to lower-poverty neighborhoods experience notable improvements in their health, including reductions in diabetes and extreme obesity. The study suggests that environments in low-income neighborhoods can contribute to poor health.
Researchers found that lung cancer patients with diabetes had higher survival rates, including 43% at 1-year and 28% without diabetes. The benefits were seen across different stages of disease, suggesting that diabetes may not be a reason to withhold standard treatment.
The Alberta Diabetes Atlas provides critical data on laboratory tests for effective diabetes management, enabling healthcare providers to make informed decisions. The atlas also helps identify disparities and improve care quality across regions and communities.
Women with polycystic ovary syndrome (PCOS) are at a higher risk for cardiovascular disease, with increased triglycerides and insulin resistance contributing to the condition. Regular screening and treatment can help mitigate this risk, but more research is needed to understand the extent of PCOS's impact on cardiovascular health.
The Waylon Fund will support state-of-the-art investigations into the genetic and genomic origins of diabetes, aiming to produce better treatments. Donations will also enable comprehensive genomic analysis using the latest technology to accelerate research.
A Kaiser Permanente study found that increasing high-density lipoprotein (HDL) levels reduced the risk of heart attacks and strokes among patients with diabetes. Patients whose HDL levels decreased had more heart attacks and strokes, with a 11% increase in risk compared to those with stable HDL levels.
The UMass Amherst School of Public Health has received a four-year, $2.5 million grant to establish a Public Health Training Center. The center will provide training to community health workers and place UMass Amherst SPHHS undergraduate student interns in local communities to develop diabetes prevention strategies. The goal is to focu...
Researchers at the University of Pittsburgh have identified a powerful molecular pathway regulating the liver's insulin management and new glucose production. FOX06, a protein family member, plays a crucial role in glucose production, leading to improved blood sugar levels when inhibited.
Scientists at Karolinska Institutet found that fat cells in overweight people have a higher capacity for storing fats but a lower capacity for ridding themselves of them. This can lead to an accumulation of triglycerides and cholesterol in the blood, increasing the risk of metabolic diseases.
Patients with uncontrolled diabetes saw faster blood glucose, blood pressure, and cholesterol level control with more frequent primary care visits every two weeks. The study found that doubling the time between physician encounters increased median times to reach treatment targets by 35-87%.
Researchers are developing a computer-delivered intervention to increase parental motivation and adolescent engagement in diabetes care. The study, targeting urban African American youth, aims to address poor health outcomes related to diabetes management.
Researchers at Joslin Diabetes Center have identified two molecular pathways that activate brown fat, a type of fat that burns energy rather than storing it. The study provides new opportunities to stimulate brown fat growth, which could lead to the development of treatments for obesity and diabetes.
A recent study published in Neurology found that people with diabetes are twice as likely to develop dementia as those with normal blood sugar levels. The study, which monitored over 1,000 participants for an average of 11 years, also found that controlling diabetes is crucial to prevent cognitive decline.
A survey of federally funded programs in 57 US states and territories found a need for specific, adapted diabetes treatment guidelines. Current national guidelines may not be optimal within each state's resources, and officials lack scientific evidence to adapt them.
The tip sheet highlights common barriers to depression disclosure among patients, including concerns about antidepressant prescriptions and confidentiality. It also explores the widespread use of NSAIDs by patients with chronic kidney disease, despite warnings against their use. Additionally, the article critiques long-established coro...
Multiple lifestyle improvements can reduce the risk of developing diabetes by up to 80%, according to a study of over 100,000 men and women. Additionally, researchers warn that Babesia, a parasitic disease, poses a threat to the nation's blood supply, highlighting the need for donor-screening strategies.
Researchers at the University of Alberta found that resveratrol prevents a metabolic syndrome in offspring born growth-restricted, characterized by glucose intolerance and insulin resistance. The study suggests resveratrol may be a potential pharmacological treatment to prevent future metabolic problems.
Researchers found an inverse relationship between blue light transmission and risk of sleep disturbances in the elderly. The study suggests that natural yellowing of the eye lens, which absorbs blue light, may be responsible for insomnia in older adults.
A review of seven studies involving over 100,000 participants found that higher levels of chocolate consumption were associated with a 37% reduction in cardiovascular disease and a 29% reduction in stroke. However, the authors caution that further studies are needed to confirm these findings.
The Homburg Cream and Sugar study reveals a correlation between triglyceride and glucose tolerance with cardiovascular outcomes in patients with stable coronary artery disease. Postprandial triglyceride levels were found to be strongly correlated with glucose metabolism, particularly in those with normal glucose tolerance.
The study predicts a significant increase in obesity rates in the US and UK, with an estimated 65 million additional obese adults in the US and 11 million more in the UK by 2030. This would lead to increased healthcare costs and a higher risk of chronic diseases such as diabetes, coronary heart disease, and cancer.
A new web-based bodyweight simulation model simulates physiological differences between people based on sex, age, height, and weight. It provides a rough dieting rule for typical overweight adults: every 10 calories per day reduction in energy intake results in about 1 pound of weight loss over 3 years.
A study by UC Davis researchers found biological indicators of toxic fat cells in those with metabolic syndrome, which may lead to diabetes and cardiovascular disease. The discovery supports a new high-risk obesity category for these conditions.
Researchers found people with diabetes alone had a 35% higher risk and those with hypertension alone had a 17% higher risk. The study also showed hyperlipidemia reduced the risk by 5%. Regular eye exams are recommended for those at increased risk of glaucoma.
A study at Joslin Diabetes Center and Children's Hospital Boston found that 'good' brown fat is prevalent in leaner children, increasing until puberty and then declining. Boosting brown fat activity may be an effective approach to combating childhood obesity.
Stephanie Lewis, a graduate student at Virginia Tech, is using computational modeling and experimental methods to identify molecules that can activate PPAR\u00b71, a therapeutic target for suppressing inflammation in chronic diseases. Her research aims to find novel compounds with insulin-sensitizing and anti-inflammatory actions.
A new study reveals that hydrogen sulfide helps protect blood vessels from the complications of diabetes by controlling an early checkpoint in related processes. The researchers found that diabetic rats have lower levels of 'swamp gas' and improved blood vessel function after treatment.
A study found that high blood pressure, diabetes, smoking, and obesity in middle age can lead to brain shrinkage and decreased cognitive function over time. The study involved 1,352 participants without dementia and found associations between these risk factors and white matter hyperintensities and executive function decline.
Researchers identify gaps in care for underserved older adults with diabetes and propose treatment models incorporating telehealth, geo-mapping, and community-based education. Better data are needed to evaluate access to care by minority groups.
A study found that measuring hemoglobin A1c levels in patients with diabetes can improve models for predicting cardiovascular disease risk. The level of risk varies among patients, and the test reflects average blood glucose levels over two to three months.
A new patient-centered medical home (PCMH) model has shown significant improvement in diabetes management, increasing adherence to evidence-based care guidelines and clinical outcomes. The study found a notable increase in patients receiving essential services such as yearly exams and vaccinations, leading to better health outcomes.
A new study found that patients with diabetes who took higher doses of Aspirin (up to 325mg/day) had a 23% lower risk of death from heart attack. Pharmacists can play a significant role in administering this treatment, working proactively with physicians and patients.
Scientists at WashU Medicine identified three unexpected players, small RNA molecules, that help a cell initiated its own demise when overloaded with fat. The research links these molecules to the cellular damage characteristic of common metabolic diseases like diabetes.
A study found that poor pre-pregnancy diet can lead to reduced birth weights, catch-up growth after weaning, and increased insulin sensitivity in offspring. These effects combined increase the risk of developing type II diabetes and obesity later in life.
Two studies suggest diet soft drink consumption may lead to increased risk of diabetes, cardiovascular disease, and other chronic conditions. Diet soda users experienced a 70% greater increase in waist circumference compared to non-users.
A major international study reveals that the number of adults with diabetes has reached 347 million, more than double the number in 1980. The prevalence of diabetes has risen or remained unchanged in virtually every part of the world over the last three decades.
A new study found that diabetes prevalence has increased globally over the past three decades, with 350 million adults affected. The study also showed that high-income countries such as the USA and Western Europe have higher rates of diabetes than other regions.
Barbara E. Corkey, PhD, is being honored by the American Diabetes Association for her 35-year contributions to understanding diabetes and its treatment. Her work has shown that oscillations in beta cell Ca2+ fluxes influence insulin secretion and that elevated glucose and lipids cause tissue malfunction in diabetes.
Researchers found that patients with RA or psoriasis who were treated with TNF inhibitors or hydroxychloroquine had a lower risk of developing diabetes. The study suggests an association between these medications and reduced diabetes risk, but the cause is not yet known.