Articles tagged with Diabetes
Researchers at University of Manchester discover new treatments for congenital hyperinsulinism by correcting gene defects in insulin-producing cells. The breakthrough has the potential to reverse cellular defects and pave way for new drugs, offering real hope for devastating condition.
A new self-monitoring blood glucose sensor developed by Arizona State University engineers and clinicians enables patients to draw tear fluid from their eyes to get a glucose-level test sample. The device aims to make blood glucose testing easier, more comfortable and potentially better control diabetes.
A four-year study aims to develop drugs that inhibit the degradation of protective metabolites in the kidneys, which are damaged by diabetes. Researchers hope these inhibitors could halt the progression of diabetic nephropathy and slow the rise of end-stage renal disease.
A research team discovered molecules that act as 'shift workers' to maintain the daily rhythm of fat metabolism in the liver. The findings suggest that disruption of this rhythm can lead to fatty liver and metabolic disorders.
A new research center at MSU will study air pollutants' impact on cardiometabolic syndrome, a collection of risk factors for cardiovascular and metabolic diseases. The team aims to understand how air pollution promotes the development of these conditions, particularly in vulnerable populations.
Young adults with chronic illnesses, such as cancer, diabetes, or epilepsy, are less likely to graduate high school and secure employment. They also experience higher rates of public assistance and disability insurance.
Researchers identified a genetic switch, estrogen-related receptor gamma (ERR gamma), that converts fast twitch fibers into slow twitch fibers with increased blood supply. This discovery offers potential therapeutic avenues for treating critical limb ischemia and other cardiovascular diseases.
Millions of people worldwide may be at risk of early death from diabetes due to poor diagnosis and ineffective treatment. In the US, nearly 90% of adult diabetics have blood sugar, blood pressure, and cholesterol levels not treated effectively.
A NYU nursing-dental research team will assess the feasibility of using gingival crevicular blood to gauge hemoglobin A1C levels as a means of diagnosing diabetes and identifying pre-diabetes. The study aims to determine if there is a correlation between A1C finger-stick and oral blood samples.
A study by the University of Michigan's C.S. Mott Children's Hospital found that the hemoglobin A1c test is not as reliable for diagnosing diabetes in children as it is for adults, potentially leading to missed cases. The authors suggest using a fasting plasma glucose test instead.
Researchers found that statin drugs can prevent free radicals from killing nerves important to maintaining vision in people with diabetes. The study suggests that oral treatment with atorvastatin can restore proper levels of nerve growth factor and preserve neurons in the retina.
Two studies investigate the role of bone marrow stem cells in diabetic therapy and islet cell regeneration, offering new therapeutic possibilities. Researchers also focus on improving pancreatic islet culture and preservation techniques to prolong the survival and functionality of islet cells in vitro.
A 22-year study found no cases of diabetes and only one non-lethal case of cancer in individuals with Laron syndrome, a growth-stunting mutation. In contrast, relatives without such mutations had higher rates of diabetes and cancer. The study suggests that blocking growth hormone activity may be protective against these diseases.
A new study has found that Native Hawaiians are at a higher risk of hemorrhagic stroke at a younger age compared to other ethnicities. The study, which analyzed data from 573 people hospitalized for intracerebral hemorrhage, also showed that more Native Hawaiians had diabetes, with 35% vs 21% in other racial groups.
A study identified blood glucose levels that predict the 10-year risk of retinopathy. Individuals with higher fasting plasma glucose and HbA1c levels were more likely to develop eye-related complications.
A study found that leptin resistance, common in diabetes, helps prevent the development of acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). Leptin resistance reduces the formation of inflexible tissue that develops in ALI and ARDS.
The study found significant variations in quality and safety across diabetes social networks, with room for improvement. Researchers recommend increasing moderation, making credentials of moderators visible, and improving privacy policies to protect patients' health information.
Researchers at Stanford University School of Medicine have identified genetic variations in a hormone involved in insulin secretion that occur more frequently in some human populations. These variants are associated with higher fasting levels of blood glucose and may help scientists understand the subtle changes in human metabolism, en...
A new study suggests that consuming inorganic nitrate from spinach can improve mitochondrial efficiency, leading to reduced oxygen consumption while exercising. This increase in efficiency may contribute to the known health benefits of fruits and vegetables, particularly leafy greens like spinach.
Joslin Diabetes Center researchers discovered that plasma kallikrein interferes with brain clotting, leading to increased bleeding during strokes. Normalizing blood glucose levels may block this effect and reduce brain hemorrhage.
A study by UTMB researchers reveals a significant increase in hypertension prevalence among older Mexican-Americans, with higher rates among those with diabetes and obesity. The study highlights the need for targeted interventions to address these factors and improve hypertension management in this growing population.
Research found that a specific microRNA (miR-503) can impair the ability of endothelial cells to form new blood vessels, leading to reduced blood flow and increased risk of amputation in diabetic patients. Inhibiting this miRNA improved blood vessel formation.
A research team led by Makoto Tominaga found that TRPM2, a body temperature sensor, plays a crucial role in regulating insulin secretion. In TRPM2-deficient mice, impaired insulin secretion and elevated blood glucose levels were observed.
A study of 41 randomized controlled trials found disease-management programs reduce glycated hemoglobin levels in diabetic patients. Frequent doctor visits are associated with greater effectiveness.
A new study reveals that Mexican immigrants who are more integrated into US culture appear less healthy and more likely to require healthcare resources. Men tend to report better health than women, but their health declines faster as they adapt to the US.
A Canadian study found that 22% of families with a child diagnosed with diabetes were food insecure, leading to poorer diabetes control and higher hospitalization rates. The researchers call for improved financial support and increased awareness among healthcare professionals to address this issue.
A new report commissioned by The National Academy on an Aging Society finds that older adults with diabetes have a lower life expectancy than those without the disease. The analysis, based on data from the Health and Retirement Study, reveals a significant increase in diabetes prevalence among boomers and seniors.
Researchers at UC Davis Health System found significantly reduced vitamin D levels in patients with metabolic syndrome living in Northern California. The study suggests that supplementation with vitamin D may reduce the risk of diabetes and heart disease, contradicting previous assumptions about adequate sun exposure in sunny latitudes.
A new study reveals how diabetes disrupts brain cholesterol synthesis, leading to neurologic complications such as depression and increased Alzheimer's disease risk. Insulin therapy restores normal cholesterol production in the brain.
A new study reveals that a key muscle protein is necessary for exercise but not normal muscle development. PGC-1-deficient mice exhibit mitochondrial problems but remain insulin-sensitive and do not develop diabetes.
Researchers at the University of Leicester identified a new way the body controls blood sugar levels after meals, involving the M3-muscarinic receptor protein. The study suggests this mechanism may be disrupted in diabetes, offering potential implications for treatment.
Children with Chronic Kidney Disease (CKD) are more likely to have mothers who were obese or had diabetes during pregnancy. Strict control of diabetes and weight loss may lower kids' risk of CKD.
Researchers found that functional cardiac stem cells can be isolated from aged and damaged hearts, with women producing more CSCs than men. The study suggests that these stem cells have the potential to regenerate heart muscle and vessel tissue, potentially treating heart failure.
Researchers at the University of Cincinnati found a link between fat around the outside of arteries and the development of cardiovascular disease, particularly in individuals with diabetes. The study suggests that this fat tissue, known as perivascular adipose tissue, can lead to inflammation and unstable blood vessels, increasing the ...
A unique program in East Harlem helps middle school students learn practical health skills, resulting in increased interest in college attendance and medical careers. The MedStart Summer Enrichment Program improves student knowledge of diseases prevalent in their community, such as asthma and diabetes.
Researchers at UCI discovered that circadian rhythms directly control PPAR-gamma, a protein essential for lipid metabolism. The discovery could lead to new pharmaceuticals targeting the specific amino acid on PPAR-gamma, offering a singular target for drug development.
The NCD Alliance warns that ignoring chronic diseases will lead to a future where healthy people are in the minority, while unhealthy children die before their parents. The alliance calls for effective actions on diet, physical activity, risks, and determinants related to non-communicable diseases.
A study in England found that coronary heart disease mortality rates vary greatly between local populations due to factors such as low socioeconomic status, white ethnicity, smoking levels, and diabetes. The study suggests that programs to reduce mortality should target population characteristics rather than healthcare services.
Scientists are exploring the therapeutic potential of (+)- pentazocine in treating diabetic retinopathy. The study aims to determine if the drug can block or promote sigma receptor action and improve retinal health in patients. Researchers also want to know if the drug is effective when given later in the disease process.
A new study found that food-insecure adults with diabetes have higher body mass indexes and greater financial constraints on food choices. However, after receiving nutrition education via telemedicine, both groups reported improved diet adherence and similar lab values associated with diabetes care.
Scientists have identified a crucial protein complex called TORC 2 that plays a significant role in insulin signaling and is linked to both diabetes and cancer. The study found that activating this complex is essential for cells to take up sugar from the blood, and that it may hold potential as a new target for treating type II diabetes.
High doses of glucosamine can cause the death of pancreatic cells, potentially increasing the risk of developing diabetes. Research by Université Laval's Faculty of Pharmacy found that prolonged exposure to glucosamine triggers a mechanism that negatively affects cell survival in the pancreas.
A study found that living in neighborhoods with poor air quality, traffic noise, and infrastructure issues significantly increases the risk of mobility problems among African Americans with diabetes. The researchers discovered that people with diabetes who live in adverse neighborhood conditions are up to 80 times more likely to develo...
Researchers found a significant link between paternal weight, diet, and an increased risk of diabetes in offspring through epigenetic changes. The study, published in Nature, showed that high-fat diets in fathers can 'program' metabolic disease in their children.
A peer partnership program improved diabetes patients' conditions by reducing blood sugar levels and increasing insulin therapy rates compared to traditional nurse care management. The study found that peer support activated patients to take a more active role in managing their condition.
A study published in Journal of Women's Health reveals a rapid increase in diabetes hospitalizations for young adults, particularly young women, which echoes the dramatic rise in obesity rates across the US. The number of hospitalizations among younger adults more than doubled from 1993 to 2006.
A new US study links larger waist sizes to significantly higher diabetes rates among American adults compared to their English peers. The research suggests that waist circumference, rather than traditional risk factors like obesity, poses a substantial health risk for Americans, particularly women.
A new study found that Latino patients with limited English skills have poor blood sugar control if seen by non-Spanish speaking doctors, even with available interpreter services. Direct communication with a Spanish-speaking doctor can improve health outcomes.
A recent study published in Cell Metabolism has identified podocytes as a crucial factor in the development of kidney failure in diabetes. The researchers found that these cells become less responsive to insulin, leading to similar kidney disease symptoms in mice with normal blood sugar levels.
Scientists have found that garlic oil can protect against heart disease in people with diabetes by reducing inflammation and weakening the heart's muscle tissue. The antioxidant properties of garlic oil were identified as a key factor in this effect.
A national epidemiologic study finds a strong link between adult diabetes and particulate air pollution, persisting after adjustment for other risk factors. The relationship was seen even at exposure levels below the current EPA safety limit.
A study published in CMAJ found that an increased waistline and high triglyceride levels during the first trimester are linked to higher glucose intolerance levels later in pregnancy. Researchers suggest that measuring waist girth in combination with triglyceride concentrations may be useful for early screening of gestational diabetes.
Researchers at the University of Kansas have developed a drug that can stop and reverse diabetic peripheral neuropathy, a debilitating condition leading to nerve death and amputations. The compound, KU-32, has been shown to inhibit molecular chaperones and restore sensory neuron function.
A UCLA study found that obesity and diabetes prevalence significantly increased in California between 2001 and 2007, with no racial or economic segment unscathed. The study recommends increasing access to recreational facilities, parks, and promoting healthy food options to combat these conditions.
A study of nearly 2,000 people with diabetes found that many remain sexually active, but experience impairment in desire and rewards. Men are more likely to express a lack of interest in sex and experience erectile dysfunction, while women report orgasm difficulties.
A new study published by the American Heart Association compares the risks of diabetes drugs rosiglitazone and pioglitazone, finding that patients taking either medication have a similar risk of heart attack, heart failure, or death. The study included over 36,000 patients and followed them for 33 months.
Researchers at Medical College of Georgia found that daily minocycline treatment can help diabetics avoid strokes or minimize damage by reducing blood vessel remodeling. This could benefit diabetics who are already at increased risk for bleeding and stroke damage.
A study published in the American Journal of Public Health found that communities with more walkers and cyclists are healthier than those relying on cars. The research analyzed city- and state-level data to show a significant link between active travel and physical activity, obesity, and diabetes rates.
Research found that black and Hispanic kidney donors are more likely to develop hypertension, diabetes, and chronic kidney disease compared to white donors. The study highlights the need for better pre-donation counseling and post-donation follow-up to address these health disparities.
Inflammation-causing cells in fat tissue contribute to the link between obesity and diabetes. Researchers found that macrophages produce cytokines that lead to insulin resistance. Losing weight reduced macrophage presence and risk of complications.