Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
Researchers at Stanford University School of Medicine discovered a previously unknown association between type-2 diabetes and high levels of polychlorinated biphenyls and gamma-tocopherol, a form of vitamin E. The novel analytic technique, called environment wide association studies (EWAS), identified these relationships surpassing tho...
A new nanotech breath sensor can detect Type I diabetes by measuring acetone levels in exhaled breath. The device is sensitive enough to detect high concentrations of acetone, even in moist air, allowing for early diagnosis and monitoring of diabetic ketoacidosis.
A computerized system can accurately detect early eye problems related to diabetes and reduce the need for expensive human screenings. The system uses digital camera images of the retina to automatically identify signs of fluid and internal bleeding associated with diabetes damage.
A study in fruit flies reveals a molecular pathway involved in dietary choices, which has implications for humans sharing the same pathway. The research opens doors to developing treatments for metabolic disorders by addressing nutritional imbalances.
A Mayo-led research team has developed potent molecules that can inhibit the breakdown of insulin in the body, keeping it working longer and potentially leading to new treatments for diabetes. The discovery may also have implications for other diseases involving insulin, such as Alzheimer's disease.
A new center will use a community-based approach to reduce cardiovascular disease risk among Latinos in East Los Angeles, where obesity-related chronic diseases are prevalent. The study will examine the role of acculturation and food environment on cardiovascular disease, with interventions targeting family and neighborhood environments.
The institution has received recognition from the Louisiana Dietetic Association (LDA) through awards to students and faculty. The LDA has presented two scholarships to Louisianatech undergraduate nutrition and dietetics students, while another student was awarded the 2010 Outstanding Dietetic Intern Award.
A study published in JAMA found that high-dose vitamin B therapy worsened kidney function and increased heart attacks and strokes in people with diabetes and kidney damage. However, the treatment did lower homocysteine levels, a risk factor for coronary heart disease.
A study published in PLOS Medicine found that rural-urban migration in India is associated with rapid increases in obesity and diabetes. The research suggests that changes in migrant behavior, such as reduced physical activity, contribute to the risk of obesity and diabetes.
Researchers have linked diabetes to a 40% greater risk of developing atrial fibrillation, with the risk rising for longer duration of diabetes and less controlled blood sugar levels.
A study in Canadian Medical Association Journal found new immigrants, especially women and those of South Asian or African descent, have a higher risk of diabetes than long-term residents. Lifestyle interventions and targeted educational programs for recent immigrants are recommended to mitigate this risk.
A study published in Molecular and Cellular Proteomics identified 57 proteins that change during diabetes-induced erectile dysfunction, including those involved in cell death, fat metabolism, and sex hormone transport. These findings may lead to new diagnostic tools and drug targets for treating ED in diabetic patients.
A wireless healthcare system for diabetes management enables patients to monitor their blood glucose levels and receive timely feedback from healthcare workers. The system has been successfully tested in a pilot study with twenty patients, demonstrating its potential to reduce healthcare costs and improve patient outcomes.
A study found that up to 42% of people with undiagnosed diabetes and nearly 18% of those with prediabetes have chronic kidney disease. This suggests a significant number of individuals may be at risk for worsening kidney disease, emphasizing the need for earlier screening and timely medical care.
A large population-based study of diabetes in China estimates that 92.4 million adults age 20 or older have diabetes, while 148.2 million adults have prediabetes, a key risk factor for cardiovascular disease. The researchers recommend national strategies for preventing, detecting and treating diabetes.
Scientists have determined the structure of a previously unseen part of the insulin receptor, which could lead to new treatments for diabetes. Understanding how insulin interacts with the receptor is crucial for developing effective therapies.
A study found that agave fructans can boost calcium absorption, potentially preventing osteoporosis. Fructans also have anti-inflammatory properties and may help regulate blood sugar levels.
Researchers discovered NG peptides in marine animals, similar to the mutant gene causing diabetes insipidus, providing new understanding of a rare form of diabetes. The discovery could help explain symptoms and treatment for around 10,000 people in the UK.
Researchers followed 1162 healthy French men and women for nine years, monitoring plasma selenium concentrations and incidence of dysglycemia. High selenium levels in men were associated with a lower risk of developing dysglycemia, while no such association was found in women.
Daily sugar-sweetened beverage consumption is linked to an increased risk of diabetes, with estimates suggesting 130,000 new cases of diabetes attributed to the increased consumption between 1990 and 2000. The American Heart Association recommends limiting added sugars to half of discretionary calorie allowance.
A recent study published in the Journal of General Internal Medicine found that adults with both diabetes and major depression are more than twice as likely to develop dementia compared to those with diabetes alone. The study, led by Dr. Wayne Katon, suggests that major depression doubles the risk of dementia in adults with diabetes.
Researchers found that HbA1c levels accurately predict future diabetes and stroke, heart disease, and all-cause mortality. The study identified people with HbA1c levels between 5.0 to 5.5 percent as within the normal range, while those at a level of 6.5 percent or greater are considered diabetic.
A new study reveals that only half of US adults with prediabetes report trying to lose weight or exercise more, highlighting a need for increased awareness and prevention measures. The researchers also found that adults with prediabetes are more likely to be male, older, and have lower educational attainment.
A new study by Northwestern University recommends raising pregnancy blood sugar levels to nearly double the risk of complications for mothers and babies. The revised guidelines suggest that a fasting blood sugar level of 92 or higher poses serious risks to both mother and baby.
A study found that single men, particularly those in unhappy marriages, had a 64% higher risk of fatal stroke compared to married men. The research, based on data from 1963, also suggested that even successful marriages may not protect against stroke.
Scientists have identified 65 abnormal proteins in diabetic mice that are reversed by treatment with the ARB medication candesartan. The study, published in Journal of Proteome Research, provides new insights into the potential benefits of high blood pressure drugs in preventing and treating diabetic retinopathy.
A study published in PLOS Medicine estimates that major diabetes complications are a significant economic burden on healthcare systems globally. The analysis found that hospital stays for stroke and heart disease were longest in Asia, while those for kidney problems were shortest. The findings provide new evidence on the cost of diabet...
The study aims to better understand the cause, diagnosis, and history of preeclampsia and diabetes in pregnant women, particularly those with hypertension or obesity. Researchers hope to develop effective treatments and therapies to save lives, reducing maternal mortality and complications.
A survey by the University of Michigan Medical School found that 28% of doctors and their diabetic patients do not agree on the most important health conditions to manage. Diabetics were more likely to prioritize symptoms such as pain and depression, while doctors focused on diabetes and hypertension.
A Michigan State University scientist has discovered the process that causes retinal cells to die, leading to diabetic retinopathy. The siah-1 protein serves as a type of chauffeur for another protein, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), shuttling it into the nucleus of Müller cells, causing vascular damage.
Scientists have identified common features of super active insulins, shedding light on their molecular structure and interaction with insulin receptors. The research holds promise for developing more sophisticated treatments for Type I diabetes, potentially offering controlled or injection-free therapies.
Research from the University of Warwick found that healthcare professionals are not adequately advising patients with medical conditions about their fitness to drive. Only 7.5% of healthcare professionals correctly identified medically unfit drivers in a paper case study, while 75% failed to offer advice on driving.
A new study analyzed 109,000 Medicaid patients taking second-generation antipsychotic drugs, which can raise the risk of diabetes and cardiovascular disease. Despite an FDA warning in 2003, most doctors did not change their baseline screening for blood sugar and cholesterol.
A new study from Duke University Medical Center found that diabetes negatively affects prostate cancer outcomes in obese white men following radical prostatectomy. However, the impact of diabetes on prostate cancer progression varies by race and weight, with lower risks observed in other subgroups.
A new UCLA study has found that metformin is safe for use in treating patients with both diabetes and advanced heart failure, suggesting improved survival rates. The study involved 401 patients who were followed for 14 years and showed a lower risk of death among those taking metformin.
Researchers have identified a leptin-controlled gene that can reverse diabetes in animals and may have similar therapeutic effects in humans. The study found that low levels of leptin can correct insulin resistance and diabetes without causing significant weight loss.
Researchers found that increasing G6PD levels can prevent negative effects of high sugar on beta cells, which produce insulin. This discovery may lead to targeted treatments for diabetes.
Researchers at Helmholtz Munich identified genetic variants associated with disturbances in lipid metabolism, which may contribute to the development of diabetes. The study provides a new approach for early diagnosis and therapy of metabolic diseases.
Researchers found that injecting triamcinolone into the eye may slow proliferative diabetic retinopathy progression, but not macular edema. Steroid treatments reduced the risk of retinopathy progression without significantly improving vision outcomes.
A Canadian study found that mortality rates among lower-income individuals with diabetes have increased, even as overall mortality rates from the disease have decreased. The study highlights the need to address barriers to adequate diabetes care in low-income populations.
A study led by Dr. Shiela Strauss found that 93% of individuals with periodontal disease are at high risk for diabetes, compared to 63% without the disease. This suggests that dental offices could serve as a valuable platform for initial diabetes screening.
Researchers found that injecting corticosteroids into the eye slowed the progression of diabetic retinopathy in a study involving 840 eyes. The treatment reduced the risk of vision loss associated with proliferative diabetic retinopathy, which affects 700,000 Americans annually.
A Kaiser Permanente study of 16,000 women in Hawaii found that Korean-American and Chinese-American women are at one-third higher risk for gestational diabetes. Pacific Islanders, Filipinos, and Puerto Ricans also face a higher risk compared to Caucasian and African-American women.
A study by Texas AgriLife Research has linked gene PFKFB3 to metabolic inflammation that leads to diabetes. The researchers believe that a focus on nutrition can prevent or reverse the disease by activating the gene.
A new study published in the Journal of the National Cancer Institute found that treatment with gonadotropin-releasing hormone agonists increases the risk of incident diabetes among men of all ages diagnosed with local or regional prostate cancer. The study also found an increased risk of cardiovascular disease, including coronary hear...
A study published in PLoS Medicine found that drivers with tighter glycemic control were more likely to be involved in motor vehicle crashes. The research suggests that a patient's HbA1c level is not necessary or sufficient for determining fitness-to-drive, questioning current traffic laws.
Dr. Donald F. Steiner has made significant contributions to the understanding of insulin secretion and related disorders through his research on proinsulin and C-peptide measurement. His work has led to major improvements in therapeutic insulin development, diagnosis of pancreatic tumors, and islet transplants.
A study published in the Journal of Ocular Pharmacology and Therapeutics reveals Pycnogenol improves microcirculation, retinal edema, and visual acuity in early stages of diabetic retinopathy. Visual acuity improved by 17/20 after two months of treatment.
Dr. Donald F. Steiner has made significant contributions to understanding insulin secretion and glucose metabolism, including the discovery of proinsulin and clinical applications of C-peptide radioimmunoassay. He will receive a Certificate of Honor and US$150,000 in recognition of his outstanding research achievements.
The number of Americans living with diabetes will nearly double from 23.7 million in 2009 to 44.1 million in 2034, and spending on diabetes will almost triple, rising from $113 billion to $336 billion. This growth is expected to add a significant strain to the healthcare system.
A new study finds that US per capita food waste has increased by about 50% since 1974 to over 1400 Calories per person per day, equivalent to 150 trillion Calories per year. This excessive energy content contributes significantly to freshwater consumption and fossil fuel emissions.
A new study published in Neurology shows pregnant women with multiple sclerosis are only slightly more likely to have cesarean deliveries and babies with poor prenatal growth rates than those without MS. Women with MS were not at increased risk for other pregnancy complications.
A new study finds that obesity and diabetes increase the risk of chest pain and skin reactions after stereotactic body radiation therapy. Patients who receive a high dose of radiation to cancer close to the chest wall are more likely to experience these side effects, highlighting the need for further research into reducing radiation-re...
The study aims to determine if lowering systolic blood pressure in hypertensive patients can reduce the incidence of cardiovascular and kidney disease, as well as slow cognitive decline. The results will be used to reevaluate optimal blood pressure levels and establish new guidelines for healthcare providers.
Researchers will develop a computer simulation model to predict the effects of prenatal risk factors like obesity and diabetes on infant health in African-American, Hispanic, and non-Hispanic white populations. The study aims to identify potential disparities in disease development and continuation across ethnic groups.
A web-based nutrition and exercise program has been shown to reduce healthcare costs for employees with cardiac risk factors. The study found that participants who visited the website at least 9 times per year had lower healthcare costs, with a $55 average decrease in costs.
Research published in Neurology suggests that people with both diabetes and Alzheimer's disease have a slower rate of memory loss than those with only Alzheimer's. The study found that diabetes may actually counteract the progression of cognitive decline in Alzheimer's patients, although the reasons for this effect are still unclear.
A new Harvard study reveals that uninsured adults with diabetes or high cholesterol are more likely to be misdiagnosed and undertreated. The researchers found significant gaps in care for these conditions, with the uninsured being more likely to experience poor blood pressure control and inadequate treatment.
A study by RAND Corporation researchers found that multifunctional electronic health records improve the quality of care in community-based primary care practices. Practices using these records showed better care for diabetes and provided certain health screenings compared to those without.
A study found that treating pregnant women with mild gestational diabetes can reduce common birth complications among infants, including smaller, leaner babies and fewer complications during delivery. Treated mothers were also less likely to develop high blood pressure or preeclampsia.