Articles tagged with Diabetes
A new study analyzed 109,000 Medicaid patients taking second-generation antipsychotic drugs, which can raise the risk of diabetes and cardiovascular disease. Despite an FDA warning in 2003, most doctors did not change their baseline screening for blood sugar and cholesterol.
A new study from Duke University Medical Center found that diabetes negatively affects prostate cancer outcomes in obese white men following radical prostatectomy. However, the impact of diabetes on prostate cancer progression varies by race and weight, with lower risks observed in other subgroups.
A new UCLA study has found that metformin is safe for use in treating patients with both diabetes and advanced heart failure, suggesting improved survival rates. The study involved 401 patients who were followed for 14 years and showed a lower risk of death among those taking metformin.
Researchers have identified a leptin-controlled gene that can reverse diabetes in animals and may have similar therapeutic effects in humans. The study found that low levels of leptin can correct insulin resistance and diabetes without causing significant weight loss.
Researchers found that increasing G6PD levels can prevent negative effects of high sugar on beta cells, which produce insulin. This discovery may lead to targeted treatments for diabetes.
Researchers at Helmholtz Munich identified genetic variants associated with disturbances in lipid metabolism, which may contribute to the development of diabetes. The study provides a new approach for early diagnosis and therapy of metabolic diseases.
Researchers found that injecting triamcinolone into the eye may slow proliferative diabetic retinopathy progression, but not macular edema. Steroid treatments reduced the risk of retinopathy progression without significantly improving vision outcomes.
A Canadian study found that mortality rates among lower-income individuals with diabetes have increased, even as overall mortality rates from the disease have decreased. The study highlights the need to address barriers to adequate diabetes care in low-income populations.
A study led by Dr. Shiela Strauss found that 93% of individuals with periodontal disease are at high risk for diabetes, compared to 63% without the disease. This suggests that dental offices could serve as a valuable platform for initial diabetes screening.
Researchers found that injecting corticosteroids into the eye slowed the progression of diabetic retinopathy in a study involving 840 eyes. The treatment reduced the risk of vision loss associated with proliferative diabetic retinopathy, which affects 700,000 Americans annually.
A Kaiser Permanente study of 16,000 women in Hawaii found that Korean-American and Chinese-American women are at one-third higher risk for gestational diabetes. Pacific Islanders, Filipinos, and Puerto Ricans also face a higher risk compared to Caucasian and African-American women.
A study by Texas AgriLife Research has linked gene PFKFB3 to metabolic inflammation that leads to diabetes. The researchers believe that a focus on nutrition can prevent or reverse the disease by activating the gene.
A new study published in the Journal of the National Cancer Institute found that treatment with gonadotropin-releasing hormone agonists increases the risk of incident diabetes among men of all ages diagnosed with local or regional prostate cancer. The study also found an increased risk of cardiovascular disease, including coronary hear...
A study published in PLoS Medicine found that drivers with tighter glycemic control were more likely to be involved in motor vehicle crashes. The research suggests that a patient's HbA1c level is not necessary or sufficient for determining fitness-to-drive, questioning current traffic laws.
Dr. Donald F. Steiner has made significant contributions to the understanding of insulin secretion and related disorders through his research on proinsulin and C-peptide measurement. His work has led to major improvements in therapeutic insulin development, diagnosis of pancreatic tumors, and islet transplants.
A study published in the Journal of Ocular Pharmacology and Therapeutics reveals Pycnogenol improves microcirculation, retinal edema, and visual acuity in early stages of diabetic retinopathy. Visual acuity improved by 17/20 after two months of treatment.
Dr. Donald F. Steiner has made significant contributions to understanding insulin secretion and glucose metabolism, including the discovery of proinsulin and clinical applications of C-peptide radioimmunoassay. He will receive a Certificate of Honor and US$150,000 in recognition of his outstanding research achievements.
The number of Americans living with diabetes will nearly double from 23.7 million in 2009 to 44.1 million in 2034, and spending on diabetes will almost triple, rising from $113 billion to $336 billion. This growth is expected to add a significant strain to the healthcare system.
A new study finds that US per capita food waste has increased by about 50% since 1974 to over 1400 Calories per person per day, equivalent to 150 trillion Calories per year. This excessive energy content contributes significantly to freshwater consumption and fossil fuel emissions.
A new study published in Neurology shows pregnant women with multiple sclerosis are only slightly more likely to have cesarean deliveries and babies with poor prenatal growth rates than those without MS. Women with MS were not at increased risk for other pregnancy complications.
A new study finds that obesity and diabetes increase the risk of chest pain and skin reactions after stereotactic body radiation therapy. Patients who receive a high dose of radiation to cancer close to the chest wall are more likely to experience these side effects, highlighting the need for further research into reducing radiation-re...
The study aims to determine if lowering systolic blood pressure in hypertensive patients can reduce the incidence of cardiovascular and kidney disease, as well as slow cognitive decline. The results will be used to reevaluate optimal blood pressure levels and establish new guidelines for healthcare providers.
Researchers will develop a computer simulation model to predict the effects of prenatal risk factors like obesity and diabetes on infant health in African-American, Hispanic, and non-Hispanic white populations. The study aims to identify potential disparities in disease development and continuation across ethnic groups.
A web-based nutrition and exercise program has been shown to reduce healthcare costs for employees with cardiac risk factors. The study found that participants who visited the website at least 9 times per year had lower healthcare costs, with a $55 average decrease in costs.
Research published in Neurology suggests that people with both diabetes and Alzheimer's disease have a slower rate of memory loss than those with only Alzheimer's. The study found that diabetes may actually counteract the progression of cognitive decline in Alzheimer's patients, although the reasons for this effect are still unclear.
A new Harvard study reveals that uninsured adults with diabetes or high cholesterol are more likely to be misdiagnosed and undertreated. The researchers found significant gaps in care for these conditions, with the uninsured being more likely to experience poor blood pressure control and inadequate treatment.
A study by RAND Corporation researchers found that multifunctional electronic health records improve the quality of care in community-based primary care practices. Practices using these records showed better care for diabetes and provided certain health screenings compared to those without.
A study found that treating pregnant women with mild gestational diabetes can reduce common birth complications among infants, including smaller, leaner babies and fewer complications during delivery. Treated mothers were also less likely to develop high blood pressure or preeclampsia.
Researchers found that physicians' practical support is associated with more favorable glycemic control outcomes. Empathic listening and patient preferences were not linked to differences in glycemic control, contrary to expectations.
Dr. Feinman will present on the controversy surrounding dietary strategies for diabetes treatment, stating that carbohydrate consumption raises blood glucose levels. He emphasizes that there is scientific consensus on this issue, but disagrees with healthcare professionals' advice.
A $5.2 million NIH grant will fund detailed genotyping of thousands of adults in Samoa to investigate genetic variation associated with obesity, diabetes and cardiovascular disease. The study aims to identify specific 'susceptibility' genes that may increase the risk of these conditions.
Research suggests that diabetes accelerates bone loss and impairs fracture healing due to increased levels of inflammatory molecules like TNF-α. This can lead to delayed bone fracture healing and an increased risk of fractures in diabetics.
A new Kaiser Permanente study found that women with diabetes are 26% more likely to develop atrial fibrillation than non-diabetic women. The study involved nearly 35,000 patients over seven years and isolated the effect of diabetes as an independent risk factor for women.
Researchers estimate diabetes prevalence in US states, finding the South has the highest rates. States like Minnesota and Alabama have high levels of blood pressure and cardiovascular disease risk.
Researchers at LSU Health Sciences Center are working on a study to prevent nerve cell death in people with uncontrolled diabetes, which causes neuropathy. The team aims to understand the mechanism of nerve cell survival after inflammatory or neuropathic insult to develop new treatment and prevention strategies.
Two Australian research studies reveal that 50% of people over 30 do not have sufficient risk factor information recorded, and only 20% with high risk receive all recommended treatments. Indigenous healthcare sites show better patient management, with 44% prescribed appropriate medicines.
A 25-year study found premature births increased by nearly 10 times, yet survival rates more than halved, with a 10% reduction in stillbirths associated with pre-term births. Researchers attribute the findings to better understanding and medically induced early births.
Researchers at Medical College of Georgia say blocking a protein that battles infection may help prevent a common cause of vision loss in chronic diseases like diabetes. The protein interleukin-6 prompts inflammation, which can lead to complications such as diabetic retinopathy.
University of Iowa researchers discovered a new molecular mechanism regulating pancreatic cells and insulin secretion in children with permanent neonatal diabetes mellitus. The mechanism involves the protein ankyrin, which regulates the KATP channel complex.
Researchers at UM Medical Center have identified haptoglobin 2 precursor as the molecular link to zonulin, a protein associated with inflammatory disorders. This discovery could lead to new treatments and diagnostic tools for celiac disease and other autoimmune conditions.
A study reveals that dynamic changes in DNA, known as epigenetic marks, play a crucial role in the development of diabetes. Researchers found that these changes occur rapidly and can be influenced by environmental factors such as diet and physical activity.
Scientists have developed a new mouse model of X-linked nephrogenic diabetes insipidus, a severe kidney disease. The model shows that selective EP4 receptor agonists alleviate the symptoms of the disease, suggesting these compounds as potential therapeutics.
Recent studies suggest that aspirin may not provide significant benefits for primary prevention in all diabetics. However, the European Society of Cardiology recommends its use for individuals with a high cardiovascular risk profile. Aspirin has been shown to reduce the risk of myocardial infarctions and strokes in this population, par...
The BARI 2D study found that diabetic patients with stable coronary artery disease benefit from a global care approach, combining medical management and revascularization strategies. A total of 42% of patients required revascularization within 5 years, highlighting the importance of comprehensive care.
Researchers have identified pathways that control partial pancreatic regeneration induced by sodium tungstate treatment, revealing its anti-diabetic effects.
A new study found that short sleep times may contribute to insulin resistance and reduced glucose tolerance, increasing the long-term risk of diabetes. The research suggests a healthy lifestyle should include adequate sleep, healthy eating habits, and physical activity to prevent diabetes.
Research found that childhood cancer survivors who received total body or abdominal radiation had a higher prevalence of diabetes, with those receiving abdominal irradiation at highest risk. The study suggests that clinicians should screen for diabetes and prediabetes in these patients and implement aggressive risk-reducing strategies.
Scientists discover a single transcription factor that can convert alpha cells into functional beta cells, increasing their number eight-fold in mice. The study shows promise for a potential new treatment for type I diabetes, where the body autodestructs beta cells leading to insulin deficiency and complications.
A novel function of a gut hormone was discovered that can potentially lower glucose levels in diabetes by activating specific receptors. The study found that CCK peptide hormone rapidly lowers blood glucose by triggering a signal to the brain and liver.
A study by the American Gastroenterological Association found that metformin reduces pancreatic cancer risk in diabetics by 60%. In contrast, insulin and other therapies may increase risk. The study's results suggest metformin could be a tool for primary prevention of pancreatic cancer.
A study of 13,817 individuals with diabetes aged 66 and older found that starting antipsychotic treatment increased the risk of hospitalization for hyperglycemia. The risk was highest among those just beginning treatment, highlighting the need for enhanced glucose monitoring.
The July/August issue of Annals of Family Medicine explores the paradox of primary care, where primary care is associated with poorer quality care for individual diseases yet higher value health care at the level of the whole person. Chronic disease management was found to be superior in community health centers and practices with nurs...
A new study in CMAJ found that an electronic tracking system improved diabetes care and clinical outcomes for patients, with 62% showing significant improvement compared to the control group. The study also showed greater patient satisfaction with their diabetes care.
A study published in The Journal of Bone and Joint Surgery found that controlled glucose levels significantly reduce complications after total joint replacement surgery for diabetic patients. Patients with uncontrolled glucose were more likely to experience surgical complications, infection, blood transfusions, and longer hospital stays.
A study of 15 women with cystic fibrosis found that assisted reproductive technology (ART) was a safe and successful option for them to become pregnant. The researchers achieved 17 pregnancies in 13 of the 15 women, resulting in 12 live births.
The International Diabetes Federation (IDF) is investigating possible links between insulin glargine and increased cancer risk based on 2009 Diabetologia study findings. The organization emphasizes that people needing insulin should not stop taking the drug, urging them to consult their doctors for advice.
Researchers developed a computer model to help medical doctors choose the optimal time to begin statin therapy in diabetes patients, reducing cardiovascular risk. The new model incorporates patient-specific data and accounts for the progression of diabetes and cost-benefit analysis.
New research reveals that diabetes costs the US economy over $174 billion annually, with a focus on lifestyle modifications and preventive care. Implementing pay-for-performance incentives can significantly reduce these costs by encouraging improved disease management and adherence to clinical guidelines.
The percentage of patients lowering 'bad' cholesterol to within target levels has nearly doubled over the last decade, with significant improvements in low-risk and high-risk groups. Researchers found that 75% of patients were taking statin drugs, and only 30% of very high-risk patients achieved their LDL target.
Researchers at Northwestern University found that young adults with low aerobic fitness levels are two to three times more likely to develop diabetes over a 20-year period. The study highlights the importance of regular physical activity and maintaining a healthy body weight to reduce the risk of chronic disease.