Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
Dr. Feinman will present on the controversy surrounding dietary strategies for diabetes treatment, stating that carbohydrate consumption raises blood glucose levels. He emphasizes that there is scientific consensus on this issue, but disagrees with healthcare professionals' advice.
A $5.2 million NIH grant will fund detailed genotyping of thousands of adults in Samoa to investigate genetic variation associated with obesity, diabetes and cardiovascular disease. The study aims to identify specific 'susceptibility' genes that may increase the risk of these conditions.
Research suggests that diabetes accelerates bone loss and impairs fracture healing due to increased levels of inflammatory molecules like TNF-α. This can lead to delayed bone fracture healing and an increased risk of fractures in diabetics.
A new Kaiser Permanente study found that women with diabetes are 26% more likely to develop atrial fibrillation than non-diabetic women. The study involved nearly 35,000 patients over seven years and isolated the effect of diabetes as an independent risk factor for women.
Researchers found that physicians' practical support is associated with more favorable glycemic control outcomes. Empathic listening and patient preferences were not linked to differences in glycemic control, contrary to expectations.
Researchers estimate diabetes prevalence in US states, finding the South has the highest rates. States like Minnesota and Alabama have high levels of blood pressure and cardiovascular disease risk.
Researchers at LSU Health Sciences Center are working on a study to prevent nerve cell death in people with uncontrolled diabetes, which causes neuropathy. The team aims to understand the mechanism of nerve cell survival after inflammatory or neuropathic insult to develop new treatment and prevention strategies.
Two Australian research studies reveal that 50% of people over 30 do not have sufficient risk factor information recorded, and only 20% with high risk receive all recommended treatments. Indigenous healthcare sites show better patient management, with 44% prescribed appropriate medicines.
A 25-year study found premature births increased by nearly 10 times, yet survival rates more than halved, with a 10% reduction in stillbirths associated with pre-term births. Researchers attribute the findings to better understanding and medically induced early births.
Researchers at Medical College of Georgia say blocking a protein that battles infection may help prevent a common cause of vision loss in chronic diseases like diabetes. The protein interleukin-6 prompts inflammation, which can lead to complications such as diabetic retinopathy.
University of Iowa researchers discovered a new molecular mechanism regulating pancreatic cells and insulin secretion in children with permanent neonatal diabetes mellitus. The mechanism involves the protein ankyrin, which regulates the KATP channel complex.
Researchers at UM Medical Center have identified haptoglobin 2 precursor as the molecular link to zonulin, a protein associated with inflammatory disorders. This discovery could lead to new treatments and diagnostic tools for celiac disease and other autoimmune conditions.
Scientists have developed a new mouse model of X-linked nephrogenic diabetes insipidus, a severe kidney disease. The model shows that selective EP4 receptor agonists alleviate the symptoms of the disease, suggesting these compounds as potential therapeutics.
A study reveals that dynamic changes in DNA, known as epigenetic marks, play a crucial role in the development of diabetes. Researchers found that these changes occur rapidly and can be influenced by environmental factors such as diet and physical activity.
Recent studies suggest that aspirin may not provide significant benefits for primary prevention in all diabetics. However, the European Society of Cardiology recommends its use for individuals with a high cardiovascular risk profile. Aspirin has been shown to reduce the risk of myocardial infarctions and strokes in this population, par...
The BARI 2D study found that diabetic patients with stable coronary artery disease benefit from a global care approach, combining medical management and revascularization strategies. A total of 42% of patients required revascularization within 5 years, highlighting the importance of comprehensive care.
Researchers have identified pathways that control partial pancreatic regeneration induced by sodium tungstate treatment, revealing its anti-diabetic effects.
A new study found that short sleep times may contribute to insulin resistance and reduced glucose tolerance, increasing the long-term risk of diabetes. The research suggests a healthy lifestyle should include adequate sleep, healthy eating habits, and physical activity to prevent diabetes.
Research found that childhood cancer survivors who received total body or abdominal radiation had a higher prevalence of diabetes, with those receiving abdominal irradiation at highest risk. The study suggests that clinicians should screen for diabetes and prediabetes in these patients and implement aggressive risk-reducing strategies.
Scientists discover a single transcription factor that can convert alpha cells into functional beta cells, increasing their number eight-fold in mice. The study shows promise for a potential new treatment for type I diabetes, where the body autodestructs beta cells leading to insulin deficiency and complications.
A novel function of a gut hormone was discovered that can potentially lower glucose levels in diabetes by activating specific receptors. The study found that CCK peptide hormone rapidly lowers blood glucose by triggering a signal to the brain and liver.
A study by the American Gastroenterological Association found that metformin reduces pancreatic cancer risk in diabetics by 60%. In contrast, insulin and other therapies may increase risk. The study's results suggest metformin could be a tool for primary prevention of pancreatic cancer.
A study of 13,817 individuals with diabetes aged 66 and older found that starting antipsychotic treatment increased the risk of hospitalization for hyperglycemia. The risk was highest among those just beginning treatment, highlighting the need for enhanced glucose monitoring.
The July/August issue of Annals of Family Medicine explores the paradox of primary care, where primary care is associated with poorer quality care for individual diseases yet higher value health care at the level of the whole person. Chronic disease management was found to be superior in community health centers and practices with nurs...
A new study in CMAJ found that an electronic tracking system improved diabetes care and clinical outcomes for patients, with 62% showing significant improvement compared to the control group. The study also showed greater patient satisfaction with their diabetes care.
A study published in The Journal of Bone and Joint Surgery found that controlled glucose levels significantly reduce complications after total joint replacement surgery for diabetic patients. Patients with uncontrolled glucose were more likely to experience surgical complications, infection, blood transfusions, and longer hospital stays.
A study of 15 women with cystic fibrosis found that assisted reproductive technology (ART) was a safe and successful option for them to become pregnant. The researchers achieved 17 pregnancies in 13 of the 15 women, resulting in 12 live births.
The International Diabetes Federation (IDF) is investigating possible links between insulin glargine and increased cancer risk based on 2009 Diabetologia study findings. The organization emphasizes that people needing insulin should not stop taking the drug, urging them to consult their doctors for advice.
Researchers developed a computer model to help medical doctors choose the optimal time to begin statin therapy in diabetes patients, reducing cardiovascular risk. The new model incorporates patient-specific data and accounts for the progression of diabetes and cost-benefit analysis.
New research reveals that diabetes costs the US economy over $174 billion annually, with a focus on lifestyle modifications and preventive care. Implementing pay-for-performance incentives can significantly reduce these costs by encouraging improved disease management and adherence to clinical guidelines.
The percentage of patients lowering 'bad' cholesterol to within target levels has nearly doubled over the last decade, with significant improvements in low-risk and high-risk groups. Researchers found that 75% of patients were taking statin drugs, and only 30% of very high-risk patients achieved their LDL target.
Researchers at Northwestern University found that young adults with low aerobic fitness levels are two to three times more likely to develop diabetes over a 20-year period. The study highlights the importance of regular physical activity and maintaining a healthy body weight to reduce the risk of chronic disease.
Research suggests that individuals with insomnia and objective short sleep duration are at increased risk for developing diabetes. A study involving 1,741 participants found that those with insomnia who slept five or fewer hours had the highest risk of diabetes, followed by those who slept five to six hours.
Research indicates that both long and short sleepers are at higher risk for developing diabetes. The adjusted odds ratio was 1.24 for short sleep (five hours per night or less) and 1.48 for long sleep (nine or more hours per night).
Researchers discovered that metformin increases the efficiency of T-cells, which boosts infection- and cancer-fighting treatments. This discovery could lead to novel strategies for vaccine and anti-cancer therapies, potentially enhancing immunological memory.
A special supplement of Diabetes Technology & Therapeutics reviews the latest research findings and critical analysis of continuous glucose monitoring (CGM) technology. CGM devices have been shown to improve glucose control, but limitations and drawbacks include finicky technology and limited physician knowledge.
The International Diabetes Federation, World Heart Federation, and UICC are urging the international community to address the growing epidemic of non-communicable diseases (NCDs), responsible for 35 million deaths each year. NCDs, including cardiovascular disease, diabetes, cancer, and chronic respiratory diseases, pose a significant t...
Research shows a high correlation between low vitamin D levels and metabolic syndrome in older adults, who are more likely to have a vitamin D deficiency. Vitamin D deficiency is linked to an increased risk of having metabolic syndrome and related metabolic diseases.
A study found that hypoglycemia may account for some portion of excess heart-related deaths in CKD patients. Patients with CKD and diabetes are at highest risk of developing hypoglycemia, which can lead to severe health complications.
A recent study reveals that approximately 6.3 million adults in the US with undiagnosed diabetes account for an estimated $18 billion in health care costs each year. The economic toll of undiagnosed diabetes is significantly higher than previously thought, rising to over $192 billion annually.
Research at Rush University Medical Center found a strong correlation between depression and visceral fat, particularly among overweight and obese women. The study suggests that depression triggers the accumulation of visceral fat through chemical changes in the body.
A new study reveals that two-thirds of the racial gap in death rates among African Americans and Caucasians is due to preventable or treatable conditions. The major contributor to this disparity is conditions with effective treatments, such as stroke, diabetes, and hypertension.
A study by Luca Saba found that diabetes and hypertension are significantly related to carotid artery wall thickness, a major risk factor for heart attack and stroke. Patients with CAWT greater than 1mm in diabetes or hypertension are at increased risk of stroke.
A study of 78,061 women found that those with psoriasis were 63% more likely to develop diabetes and 17% more likely to develop hypertension than women without psoriasis. Systemic inflammation in psoriasis may be a biologically plausible explanation for the association.
Researchers found that mirthful laughter reduced stress hormones and increased HDL cholesterol in diabetic patients, lowering the risk of cardiovascular disease. The study suggests that adding laughter therapy to standard care may improve health outcomes.
Studies link periodontal disease to infant prematurity, diabetes, and stroke. Treating pregnant women with scaling and root planing can save nearly $14 million worldwide.
A large study found that glitazone diabetes drugs increase the risk of diabetic macular edema by 60%, a condition that can lead to progressive visual loss. The study's results suggest that ophthalmologists should consider the role of glitazones when treating patients with DME.
A study of 4,060 adult patients with diabetes found that on-demand scheduling did not improve outcomes compared to traditional scheduled visits. The study suggests that timely follow-up for chronic disease management may be compromised by on-demand scheduling.
A recent study comparing coronary artery bypass graft surgery (CABG) with catheter/balloon/stent percutaneous intervention (PCI) found that CABG may be a better option for patients with diabetes and those aged 65-75 years. The research, involving 7812 patients, revealed lower mortality rates in these subgroups.
A new study published in The Lancet found that coronary artery bypass graft may be a better treatment choice than percutaneous coronary intervention (angioplasty) for patients with multi-vessel coronary artery disease who have diabetes and are older than 65. In contrast, PCI may be the best option for patients 55 years and younger.
Studies have shown that patients with type II diabetes have lower blood levels of hydrogen sulfide, a compound that helps regulate blood pressure. Lower H2S levels may contribute to microvascular dysfunction and increased risk of vascular complications in these patients.
A study found a widening gap between heart disease guidelines and patients' lifestyles, with doctors prescribing more drugs while lifestyles remain unchanged. Lifestyle interventions are crucial to prevent heart disease, but comprehensive programs are lacking.
A study of 387 diabetics found that home telemonitoring significantly reduced deaths compared to a non-monitored group. Telehealth provided a safety net, allowing patients to age in place and live where they wanted, with educational resources also being offered.
Researchers found that nearly half of participants lost 5% or more of their body weight and kept it off for at least six months. The 12-week Fit Body and Soul program focused on behavioral changes to prevent future diabetes in high-risk church members.
Researchers at Ohio State University Medical Center have discovered a gene, BDNF, that can improve insulin sensitivity, reduce fat mass, and lead to weight loss when active in the hypothalamus. The study involves injecting the gene into mice and shows promising results for treating obesity.
Researchers at Columbia University Medical Center found that diabetes and high cholesterol are associated with faster cognitive decline in Alzheimer's patients. The study also suggests that controlling vascular conditions may help delay the progression of the disease.
Studies show metabolic syndrome and obesity linked to increased risk of cognitive impairment, dementia in both men and women. Research also reveals unique associations between body mass index, weight changes, and dementia risk.
The number of Americans with diabetic retinopathy is projected to triple by 2050, while cataracts will increase by 235% and glaucoma among elderly Hispanic individuals will increase 12-fold. Ophthalmologists must collaborate with other clinicians to help patients control their diabetes before eye complications worsen.
In the occupied Palestinian territory (OPT), chronic diseases such as heart disease, cerebrovascular disease, diabetes, and cancer are leading causes of death. The Palestinian National Authority's response has been limited due to military occupation and its consequences on the healthcare system.
Researchers at the Salk Institute found a protein called CREB that promotes insulin resistance in obese mice. Blocking CREB's activity improved insulin sensitivity and reduced inflammation, suggesting a potential therapeutic target for type II diabetes. The study provides hope for new treatments that don't require weight loss.