Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
A new study published in JAMA found that low-income women with diabetes have a more than 50% increased risk of experiencing postpartum depression. The research suggests that healthcare facilities and clinicians should pay attention to managing mental health concerns in women with diabetes during pregnancy and the postpartum period.
Low-income pregnant women and new mothers with diabetes have nearly twice the risk of experiencing depression during and after pregnancy than women without diabetes. The study, published in JAMA, found that women with any form of diabetes were significantly more likely to experience some indication of depression during pregnancy or pos...
A new letter in JAMA contests an earlier study's associations between bisphenol A and various health issues, citing statistical limitations. The authors conclude that the findings could be due to chance rather than real health concerns.
Researchers found that diabetic patients are less likely to develop acute respiratory failure during severe sepsis. They discovered that people with diabetes and sepsis were more likely to develop acute renal failure than those without diabetes.
A recent study found that individuals with new diagnoses are more likely to adopt healthier habits than those without recent new diagnoses. Smokers who received at least one diagnosis had 3.2 times the odds of quitting compared to those without a diagnosis.
Researchers have found that bone marrow cells can promote the regrowth of both blood vessels and the protective lining of nerves in diabetic animals. This discovery has potential implications for treating neuropathy in people with diabetes.
The Burroughs Wellcome Fund Inter-school Training Program in Metabolic Disease (BWF-ITP-MD) combines multiple disciplines to understand metabolic diseases, from molecular mechanisms to population health. The program aims to develop comprehensive insights and system strategies to curb the epidemics of obesity and diabetes.
A twin study found that getting diabetes before 65 significantly increases the risk of Alzheimer's disease and other dementia. The study also suggests that maintaining a healthy lifestyle during adulthood can reduce this risk.
Researchers at the University of Pittsburgh School of Medicine have successfully induced human insulin-producing beta cells to replicate in a living animal and in the lab. The discovery could improve models and methods for studying diabetes and lead to techniques for generating new beta cells in patients with diabetes.
A study published in the Journal of Hospital Medicine found that US academic medical centers do not meet current American Diabetes Association hospital diabetes care standards. The research highlights the need for improved insulin therapy and standardized protocols to enhance patient outcomes.
Patients with diabetes and dementia show different brain injury patterns compared to those without diabetes. Diabetes treatment affects the type and extent of brain damage in dementia patients.
A new study by researchers at the University of Alabama at Birmingham found that geographic and racial differences do not fully explain the South's higher stroke death rate, with a greater-than 40 percent higher mortality rate in eight southeastern states.
Researchers at Baylor College of Medicine found that the COUP-TFII protein helps control fat cells and energy metabolism. Breeding mice with only one copy of the gene led to smaller fat cells and increased sensitivity to insulin, making it a potential target for diabetes treatment.
The Institute for Research in Biomedicine (IRB Barcelona) will coordinate two European health research projects on malaria and diabetes. The Mephitis project aims to find new anti-malarial compounds, while the MITIN Project applies bioinformatics to understand complex diseases like diabetes.
A new report suggests that routine dental cleanings and periodontal scaling can lower medical care costs for people with diabetes. The study found significant reductions in medical expenses, with costs decreasing by an average of 11-12% per month.
Scientists have found a genetic variation at the hexokinase-1 gene associated with glycated hemoglobin, an index of long-term blood glucose concentration. The study analyzed 14,618 women and found that variations at this gene are an important determinant of glycated hemoglobin concentrations.
A meta-analysis of studies found that patients with diabetes diagnosed with cancer have a higher risk of death compared to those without diabetes. The study, published in JAMA, suggests that pre-existing diabetes is associated with an increased risk of all-cause death following cancer diagnosis across various cancer types.
A study of California adults found that interruptions in Medicaid coverage are associated with a higher rate of hospitalization for common health conditions. States require frequent reenrollment, leading to gaps in coverage and increased hospital spending.
Diabetic retinopathy, cataracts, and glaucoma cases among Americans with diabetes are estimated to increase significantly by 2050. The number of people with diabetes-related retinal disease is projected to rise, causing vision loss and disabilities that can lead to depression, reduced mobility, and reduced quality of life.
Scientists at Oxford University created a mouse model of neonatal diabetes that mimics the human condition, showing the V59M mutant Kir6.2 protein disrupts insulin production and leads to increased blood glucose levels.
Researchers discovered 30 genetic variants associated with cholesterol levels, including 11 new ones, which could lead to more effective therapies. The study also found links between melatonin, sleep patterns, and small increases in glucose levels, increasing the risk of diabetes.
A study found that ascorbic acid supplementation in diabetic rats improved myenteric neuron density by 14% and cellular area by 4.4%, suggesting moderate neuroprotection.
A research team at the University of Pennsylvania School of Medicine has discovered a key molecular partnership that coordinates body rhythms and metabolism, leading to leaner mice and improved insulin sensitivity. The study suggests that disrupting this partnership could be a valuable new weapon in the fight against obesity and diabetes.
A study found that older adults taking rosiglitazone had a 15% higher rate of death and 13% greater risk of heart failure compared to those taking pioglitazone. The authors highlight the need to consider all-cause mortality risk in elderly patients, as rosiglitazone's cardiovascular effects may be more pronounced.
A drug based on a garlic chemical, vanadium-allixin, reduces blood glucose levels in diabetic mice, offering promise as an oral treatment for diabetes. The study aims to test the drug in humans in future work.
A study by Associate Professor Katherine Samaras reveals that HIV treatment causes inflammation, leading to increased cardiac and metabolic risk. Patients with HIV-infection tend to gain weight around their abdomen, increasing their risk of heart disease and diabetes.
A new study found that women with diabetes have a seven times higher risk of severe pelvic girdle syndrome. Hormonal factors, such as relaxin, may play an important role in the development of the condition.
Retired NFL players had a lower prevalence of diabetes and hypertension compared to control groups, but higher rates of elevated cholesterol and impaired fasting glucose. Staying physically active may help protect against these health risks in former athletes.
A study by the American Heart Association found that Hispanic patients were 57% less likely than Caucasian patients to undergo coronary artery bypass surgery (CABG) one year after successful angioplasty. Hispanics also had a trend toward lower rates of overall repeat revascularization procedures, including stenting and bypass surgery.
Children born to mothers with pregnancy-related diabetes are twice as likely to experience language development problems. Research from Université Laval found that babies' brains develop differently due to gestational diabetes, affecting vocabulary and grammar skills even after starting school.
A study of over 300 diabetics and their caregivers will measure the impact of insulin pump technology on quality of life, attitudes towards treatment, and lifestyle changes. The research aims to provide insights into the clinical implications and potential coverage by Medicare and health insurance providers.
A study published in Neurology found that people with Alzheimer's disease who also have diabetes are twice as likely to die sooner, while those with high blood pressure are two-and-a-half times more likely. Hispanic individuals lived four years longer than non-Hispanic whites after diagnosis.
A study of 1,402 fourth-grade students found high diabetes risk factors and obesity rates among children from poor families. Whole-grain intake was linked to lower heart failure risk, while high-fat dairy and egg consumption increased the risk.
A study of over 40,000 women found that those who gained more than 40 pounds during pregnancy were nearly twice as likely to have a heavy baby. Heavy babies are at risk for birth complications and may become overweight or obese children and adults.
A Stanford study found that gene expression patterns in mice with type-1 diabetes were similar to those in humans before symptoms appeared. The researchers identified clusters of genes that participated in coordinated changes over time, which may provide an early warning for pre-diabetics.
Researchers discovered that using hydroxychloroquine reduces diabetes risk in rheumatoid arthritis patients by 53%. The study suggests HCQ improves glucose tolerance, preventing diabetes onset.
A new study by Stanford researchers found that newer, more expensive diabetes medications do not automatically translate to improved patient outcomes. The study suggests that the higher cost of these medications may be due in part to increased use and diagnosis rates, rather than actual clinical benefits.
The Rutgers University Cell and DNA Repository has received two major NIH awards to support investigations into the genetics of mental disorders, metabolic diseases, and digestive health. The funds will enable researchers to study the genetic causes of complex diseases such as autism, bipolar disorder, and diabetes.
Researchers discovered that injecting human recombinant interleukin-6 improved insulin sensitivity and glucose absorption, increasing fat metabolism genes. A preliminary study suggests this molecule could help prevent diabetes and obesity in humans in the medium term.
People with diabetes are at higher risk of visual impairment due to diabetic retinopathy and other ocular conditions. Approximately 11% of American adults with diabetes have some form of visual impairment, compared to 5.9% without the disease.
A research team has found evidence linking bisphenol A to diabetes and heart disease in adults. The study, published in the Journal of the American Medical Association, analyzed data from over 1,400 adults and found a significant association between high BPA levels and an increased risk of these diseases.
A two-year study of over 10,000 Medicare beneficiaries with diabetes found that depression was associated with a 36% increased risk of dying from any cause. Participants with both diabetes and depression were more likely to be female, have severe medical illness, and less likely to be African-American.
Researchers have found a potential solution for diabetic gastroparesis by increasing production of a key molecule in the digestive process. The study, published in Gastroenterology, shows that a red blood cell derivative can restore normal gastric emptying and improve glucose control.
The integration of sophisticated medical technologies with advanced information systems and clinical expertise can significantly improve patient care while lowering treatment costs. Real-time monitoring technologies, such as Zephyr's Smart Fabric technology, can detect key metabolic functions and provide significant savings in chronic ...
Researchers at UNC School of Medicine have transformed human skin cells into insulin-producing cells using pluripotent stem cell technology. This breakthrough may lead to new treatments or even a cure for the millions of people affected by diabetes.
A study found that individuals with diabetes and those with larger stomach pouches are less likely to successfully lose weight after gastric bypass surgery. The researchers examined data from 361 patients who underwent the procedure between 2003 and 2006.
A study by Indiana University School of Medicine researchers found that community-based exercise organizations like the YMCA can effectively prevent diabetes. Participants in the program lost an average of 12.5 pounds and had significant reductions in total cholesterol.
Researchers discover that a certain drug, known for its pain-relieving properties, can protect the retina from damage caused by diabetes. The study found that sigma receptor activation helps prevent retinal damage and vision loss.
A community-based diabetes prevention program using the YMCA as a vehicle for education and lifestyle intervention has shown promising results. Participants achieved significant weight loss and improvements in cholesterol levels, suggesting the potential for widespread dissemination of evidence-based strategies.
The TRANSCEND study found that telmisartan modestly reduced cardiovascular events and hospitalizations for heart-related issues in patients with vascular disease or high-risk diabetes. The drug also had a lower rate of permanent discontinuation due to hypotension, according to the randomized controlled trial.
Diabetic patients face accelerated atherosclerosis, increased risk of restenosis and late mortality when undergoing PCI. DES has been associated with mortality benefit in patients with multivessel disease, but results are mixed for diabetic patients.
A study published in Archives of Neurology found that individuals with mild cognitive impairment are more likely to develop diabetes, have longer durations of diabetes, and experience greater severity. Poor blood glucose control over time may lead to neuronal damage, contributing to cognitive impairment.
A new survey reveals that 33% of individuals with diabetes who take insulin injections experience dread related to them, while 52% do not proactively discuss their concerns with healthcare providers. However, many healthcare professionals are aware of the impact of insulin injections on patients' quality of life and have initiated dial...
A commonly used diabetes monitoring test could be repurposed to screen for and diagnose diabetes, identifying millions of people with undiagnosed disease. The hemoglobin A1c test measures long-term glucose control, offering advantages over current testing methods that require fasting or are affected by recent meals and diet.
Montreal researchers have shown that insulin-producing β-cells can dedifferentiate into stem-like cells, a key finding with implications for regenerative therapies and the development of innovative treatments. The study's results validate the potential of a peptide called INGAP to induce new islet formation in the pancreas.
Diabetes can cause gangrene and skin ulcers due to restricted blood supply, leading to impaired healing and tissue dysfunction. New therapies may be developed by suppressing the action of p75NTR, a gene responsible for promoting blood vessel growth in diabetes.
A systematic review of 13 observational studies found that diabetes mellitus increases the risk of active tuberculosis by about a factor of three, suggesting a possible role in over 10% of TB cases in India and China.
Hispanic patients with diabetes are less likely to receive eye exams and are often unaware of the ocular complications of diabetes. The study found that nearly half of those with diabetes for more than a year had never had a dilated eye exam.
A new vision screening device can detect metabolic stress in the retina, potentially identifying diabetes early. The instrument measures flavoprotein autofluorescence (FA) activity to detect abnormal metabolism and tissue damage.
A study by Dr. Con Mallidis from Queen's University, Belfast, UK, found that diabetes causes DNA damage in sperm and decreases their ability to repair DNA, leading to decreased fertility. The researchers identified AGEs as a key factor in this damage.