Articles tagged with Diabetes
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A study found that extreme obesity is associated with a higher prevalence of hypertension, diabetes, and high cholesterol in women. Women with extreme obesity were more likely to die over the average 7-year follow-up period than those in other weight categories.
A Canadian study found that people with diabetes are up to four times more likely to have cardiovascular disease as those without it. Diabetes leads to an earlier high-risk category for CVD, with diabetic men and women being about 15 years younger than non-diabetic counterparts in the same risk group.
Researchers at U of T confirm the GI's reliability as a predictor of blood glucose levels, despite concerns over unpredictable outcomes. The study found that 90% of variation was explained by carbohydrate content and GI values, validating the concept's effectiveness in managing blood glucose.
A recent animal study found that trans fat consumption can lead to weight gain despite controlled calorie intake. The study, led by Kylie Kavanagh and Lawrence L. Rudel, discovered that male monkeys fed a western-style diet rich in trans fat gained 7.2% more body weight compared to those on a monounsaturated fat diet.
William H. Herman suggests that glycosylated hemoglobin test may not be suitable for making diabetes diagnosis, and instead recommends blood glucose tests after a special sugary drink for accurate diagnosis. Population-level studies show how screening can optimize detection of impaired glucose tolerance and prevent diabetes complications.
Researchers identify abnormal fasting glucose levels as a risk factor for neuropathy, suggesting an earlier stage of disordered glucose metabolism. The study's findings support the hypothesis that impaired glucose tolerance may be a milder precursor to neuropathies associated with diabetes.
A new study suggests that prepaying benefits for diabetes prevention could save healthcare costs by preventing millions of individuals from developing the disease. By sharing costs with employers and individuals, private health insurers and Medicare can cover lifestyle interventions, reducing the economic impact of obesity and diabetes.
Researchers at the University of Rochester Medical Center have made a groundbreaking discovery about the relationship between stress response and insulin regulation in flies. By boosting a molecular signal called JNK, they found that flies can live up to 85 days longer, opening up new avenues for understanding human diabetes and aging.
Researchers found that mice lacking pancreatic beta cell M3 receptors developed impaired glucose tolerance and reduced insulin release. In contrast, mice with increased M3 receptors showed improved glucose tolerance and insulin release, becoming resistant to developing symptoms of diabetes.
A novel therapeutic approach has been discovered by the University of Manchester team, using a DNA-binding protein to stimulate genes and promote nerve growth. The preclinical results have been encouraging, with initial-stage clinical trials in the US showing promising progress in managing diabetic neuropathy.
Researchers found that a combination of beta-blockers, calcium antagonists, and ACE inhibitors effectively lowers blood pressure in Hispanic patients while reducing their risk of developing diabetes. The study showed a 19% increased risk of diabetes in Hispanic patients but a 15% decreased risk with the verapamil-trandolapril strategy.
A new study has demonstrated the use of PET imaging to track diabetes progression by measuring beta cell mass. The method uses a molecule expressed in both beta cells and the central nervous system, allowing for non-invasive imaging of beta cells in rats and potentially human subjects.
The Australian Diabetes, Obesity and Lifestyle Study found that approximately 100,000 adults develop diabetes annually, with nearly 600 people progressing to obesity every day. The study also revealed a significant increase in hypertension and chronic kidney disease among the Australian population.
Uninsured adults are less likely to receive preventive services and treatment for chronic illnesses compared to insured adults. Higher-income uninsured individuals also exhibit decreased use of recommended healthcare services, suggesting that lack of insurance is not solely associated with lower-income populations.
A study by University College London found that middle-aged English people have lower rates of diseases such as diabetes, high-blood pressure, and lung cancer compared to their American peers. The differences were confirmed through analysis of biological markers, suggesting that the health disparities are not just due to reporting biases.
A study comparing health outcomes in US and English citizens reveals that Americans are much sicker than their English counterparts. The SES-health gradient appears equally strong in both self-reports and biological measures of health.
A study of 152 patients with diabetes found that taking sertraline significantly reduced the risk of depression recurrence. After one year, 65.8% of patients remained in remission compared to 47.9% on placebo.
The editorial concludes that inhaled insulin is not suitable for everyone with diabetes, citing high costs and limited long-term safety data. Despite this, individual physicians should discuss its use with patients on a case-by-case basis.
Data from the National Health Interview Survey show a significant link between obesity and increasing diabetes incidence. Lifestyle interventions, including moderate weight loss and exercise, can prevent or delay diabetes onset in high-risk adults.
A recent study published in Archives of Surgery found that tightly controlled blood sugar levels before surgery can significantly reduce the risk of postoperative infections in diabetic patients. The research involved 490 diabetic patients who underwent major noncardiac surgery between 2000 and 2003, with 197 having good glycemic control.
Researchers discovered that p110 alpha controls insulin signals, frequently mutated in cancer, but mice with a single mutation showed no signs of developing diabetes. The findings have immediate implications for testing p110 alpha-specific inhibitors for human therapies.
Diabetic patients undergoing periodontal therapy show improved metabolic control, with a 20% reduction in HbA1c levels. The study suggests that periodontal treatment may help diabetic patients move from the 'at-risk' category to a healthy range.
In a study on Huntington disease, researchers found that cystamine increased brain levels of protective protein HSJ1b and BDNF, suggesting a promising candidate for treatment. The study also revealed that cystamine raises BDNF in an HSJ1b-dependent manner.
The University of Pittsburgh study found significant improvements in clinical, behavioral, and psychological indicators for patients receiving the chronic care model (CCM) intervention. Patients and providers received diabetes-control education, leading to better blood glucose control, HDL cholesterol, and diabetes knowledge.
A recent study found that diabetes care has improved over the past decade, but two in five people with diabetes still have poor control of cholesterol and blood pressure. Lifestyle changes can significantly reduce the risk of heart disease for those with mild hypertension.
A recent study by the American Heart Association found that people who slept for five or fewer hours per night were more likely to develop hypertension than those who slept seven or eight hours. This association was observed even after controlling for other risk factors, such as obesity and physical activity.
A recent study conducted by Dr. Charles Simonton and the STENT Group found that both drug-eluting stents performed well in controlling restenosis in diabetics, with paclitaxel-eluting stents potentially showing better outcomes for insulin-treated diabetic patients.
A survey of 2,461 diabetes patients found that many had a less-than-accurate view of healthy body weight. Women were more likely to correctly identify a normal BMI range as healthy, while men and obese individuals often overestimated their ideal weights.
A study found that feedback on performance given to primary care physicians decreased clinical inertia and improved glucose levels in their patients. The intervention, which included physican-specific feedback and computerized reminders, led to sustained improvements in physician behavior and patient outcomes after three years.
Research found that young pregnant women with pregnancy complications are at increased risk of heart disease and death, with the risk doubling after adjusting for medical factors. Smoking during pregnancy was also found to significantly increase the risk of all-cause death and cardiac death.
Researchers found that people with diabetes from different ethnic groups have varying levels of muscle mass in the left ventricle, a key indicator of heart health. In white, African-American, and Hispanic individuals, increased muscle mass was linked to subclinical atherosclerosis and high blood pressure.
A study found that older adults in North Carolina predominantly use food home remedies and other home remedies for health management, often as a form of self-care. The study also revealed significant differences in CAM therapy use among ethnic groups, with African-Americans and Native Americans showing higher rates of use.
A recent study published in Diabetes reveals that diabetes rates in the US have increased dramatically over the past decade, leading to a sharp rise in hospitalizations and deaths from coronary heart disease. As a result, progress made in reducing illnesses and deaths from this condition may be put at risk.
Lifelong calorie restraint is crucial for preventing excess weight and age-related health issues such as high blood pressure and diabetes. Studies with rhesus monkeys show that maintaining a constant healthy body weight can improve overall health and prolong lifespan.
Research highlights importance of early oral health screenings for young patients with diabetes, as gum disease onset is younger than previously recognized. Studies show significant disparities in dental care access and a perceived lack of need among diabetic patients.
A recent study published in the Canadian Medical Association Journal found a strong correlation between height and the risk of amputation among patients with diabetes mellitus. The research showed that every 10-cm increase in height was associated with a 16% higher risk of amputation, even among those with well-controlled diabetes.
A study by UF researchers reveals that diabetic patients' cells have difficulty repairing damaged blood vessels due to low nitric oxide levels. The team found a way to improve the cells' movement and repair ability using nitric oxide, opening up possibilities for new treatments.
Studies found that erectile dysfunction is common among men and associated with various chronic diseases, including heart disease. The condition was also linked to increased risk of future cardiovascular events, diabetes, and hypertension.
Researchers found that therapies targeting brain insulin receptors can significantly improve blood sugar control and reduce insulin dose requirements. Gene therapy interventions also increased the animals' response to insulin therapy about 2-fold.
A Northwestern University study found that middle-aged individuals with higher body mass indexes had significantly higher risks of hospitalizations for and deaths from heart disease and diabetes in older age. Having a normal BMI in young adulthood and middle age confers significant health benefits.
The new JBS 2 guidelines focus on cardiovascular disease as a whole, including those with hardened arteries and diabetes. Screening is recommended for adults at high risk of cardiovascular disease, with targets set for blood pressure, cholesterol, and sugar levels.
The Joslin Diabetes Center study found that online discussion boards provide a less threatening way to discuss sensitive concerns about diabetes. The study, which tracked over 330,000 visits to the discussion boards, found that nearly 75% of respondents rated participation as having a positive effect on coping with diabetes.
Two landmark papers unveiled significant breakthroughs in preventing amputations in diabetes patients. Novel Negative Pressure Wound Therapy technology has been shown to simplify complex wounds, while powerful antibiotics have demonstrated comparable efficacy when administered once daily.
A survey found that nearly half of people with diabetes are not using aspirin as prescribed, despite its proven benefits in reducing heart attack and stroke risk. The study highlights the need for better communication between healthcare professionals and patients, particularly those with diabetes who are at higher risk.
A population study of over 3,000 adults found that hostility does not affect long-term heart health in women, unlike men. Men with high hostility scores were twice as likely to experience recurrent heart disease events.
A study identified measurable differences in the skin of diabetes patients, particularly those with peripheral neuropathy, before ulcerative foot disease develops. The findings also showed reduced energy reserves in foot muscles, highlighting microcirculatory changes as a major factor.
Researchers found that people with diabetes are 1.4 times more likely to develop colon cancer compared to those without the condition. The study analyzed data from a nationally representative sample of patients and controlled for various factors, including age and obesity.
A randomized controlled study showed a significant reduction in systolic blood pressure (SBP) of 7.4 mmHg in the treatment group, compared to a rise of 3.1 mmHg in the control group. The device also demonstrated a dose-response relationship, with increased breathing exercise sessions resulting in greater SBP reduction.
A Columbia University study shows that aprotinin decreases blood glucose levels and insulin resistance in diabetic patients undergoing CABG surgery, reducing the risk of complications. The study's findings have important implications for the management of blood glucose levels during heart surgery.
A study by Fox Chase Cancer Center found no significant impact of type II diabetes on the initial profile or treatment outcomes of prostate cancer. However, men with type II diabetes experienced significantly worse long-term overall survival rates compared to those without diabetes.
Three patients underwent gastric bypass surgery and developed severe hypoglycemia, requiring partial or complete pancreas removal. Abnormal insulin-producing islet cell proliferation was found in all cases.
US kidney failure rates have stabilized over the past two decades, with diabetes and high blood pressure remaining leading causes. Despite progress, racial disparities persist, particularly among African Americans, who continue to experience higher rates of new cases.
A study of 906 breast cancer patients found that comorbidities such as diabetes and hypertension contributed to racial disparities in survival rates. Black patients had shorter overall survival rates, while whites were more likely to die from competing causes.
The PROactive study found that Takeda's ACTOS (pioglitazone HCl) significantly reduced the combined risk of non-fatal heart attacks, strokes, and deaths by 16% in high-risk patients with type-2 diabetes. This led to a 10% reduction in the primary combination endpoint of seven different macrovascular events.
Researchers at Mayo Clinic found nerve damage due to high blood sugar levels can begin as early as 20 years into the disease. The study of over 500 patients showed steady worsening of nerve conduction tests even in those with normal values, highlighting the importance of controlling diabetes from onset.
Researchers found that smokers had a significantly higher incidence of developing diabetes compared to non-smokers, even after adjusting for other risk factors. The study suggests another poor health outcome associated with cigarette smoking, supporting current surgeon general's warnings.
Researchers have identified a potential new treatment for insulin-dependent diabetes by targeting natural killer T cells. The study shows that multiple doses of alpha-galactosylceramide can reduce the production of interferon-gamma, which helps destroy transplanted islet cells.
High insulin levels block stress hormones, leading to excessive fat storage and energy imbalance. The study provides new understanding of insulin resistance in Type II diabetes and its potential link to obesity.
The partnership aims to stimulate and accelerate European research into beta cell function and survival, aiming to move towards a cure for diabetes. Approximately 194 million people worldwide suffer from diabetes, with the number expected to exceed 333 million by 2025.
A study of over 16,000 participants found a graded association between high blood glucose levels and increasing coronary heart disease risk. Non-diabetic individuals with elevated HbA1c levels were at significantly increased risk of heart disease.