Articles tagged with Diabetes
Researchers at McGill University Health Centre have identified a new gene involved in type 1 diabetes, bringing the total to five genes responsible for the disease. The discovery using high-density DNA microchip technology provides a promising step towards developing effective treatments and prevention methods.
Research at Harvard Medical School found that uninsured adults before age 65 require more intensive and costlier care than those with private insurance. This can lead to costly complications and reduced health needs after age 65.
A daily pint of milk reduces the risk of metabolic syndrome by 62%, while regular dairy consumption lowers the risk by 56%. The study found that around one in seven men had the syndrome at entry into the study, with those who consumed more dairy produce having a lower risk.
A new study found that patients treated with HCQ were less likely to develop diabetes, and those who did were more likely to manage their disease without medications. The medication may also be suitable for people at high risk of developing diabetes as a preventive therapy.
Research reveals nearly half of people with diabetes use alternative therapies, which can interact with conventional medications and affect blood sugar levels. Healthcare professionals must be included in discussions about these therapies to document their use and identify potential problems.
The study found that the death rate for men with diabetes declined by 43% between 1971 and 2000, while the death rate for women with diabetes did not change. The authors suggest that different approaches may be needed to improve health outcomes for women with diabetes.
A recent study from the University of Missouri-Columbia found that exercise alone led to significant improvements in blood glucose levels for people with diabetes, outperforming diet and medication changes. The meta-analysis of 10,455 subjects showed that physical activity had equal benefits across age groups and genders.
A study found that men and women with diabetes at age 50 and older have a significantly reduced life expectancy and fewer years without cardiovascular disease. This increase in risk of illness and death is attributed to the global prevalence of Western lifestyle habits, leading to an alarming rise in diabetes cases.
Recent falls in US coronary heart disease deaths can be attributed to a combination of lifestyle changes and medical therapies. Despite decreases in risk factors such as smoking and high cholesterol, increases in obesity and diabetes offset the progress.
Research found that smokers with diabetes received increased cessation advice since 2004's performance-related GP incentives. This led to reduced smoking rates among those with the condition, especially in disadvantaged groups.
A study in London found that introducing financial incentives for physicians improved support for smoking cessation and reduced smoking prevalence among people with diabetes who smoke. The introduction of pay-for-performance incentives has the potential to improve quality of care for these patients.
A new study published by Duke University Comprehensive Cancer Center found that patients with chronic illnesses like diabetes or heart disease are no more likely to receive an early cancer diagnosis due to frequent healthcare interactions. Screening is still crucial regardless of medical management.
A Mayo Clinic research team has developed a simple tool to enhance medication adherence in diabetes patients, with 84% of users showing improved compliance. The decision aid sparks conversation between doctors and patients about medication risks and benefits, leading to better-informed decisions.
A new University of Leicester study reveals that low levels of physical activity among inner city school children have reached epidemic proportions. Over 3500 pupils from five secondary schools were surveyed, with half spending over 4 hours daily watching TV or playing computer games.
A new study published in Diabetes Care identifies two critical factors that increase the risk of recurrent wounds in diabetics: the location under the big toe and poor blood flow. This information can help physicians predict and prevent complications, including gangrene and amputation.
A recent study has linked sleep apnea to a higher incidence of gestational diabetes and pregnancy-induced high blood pressure. The researchers analyzed data from over 4 million deliveries and found that women with sleep apnea were more likely to develop these conditions, particularly when their weight was taken into account.
Scientists at the University of Wisconsin-Madison have developed a powerful analytical tool capable of measuring molecular structures quickly and accurately, capturing intermediate steps of protein folding and revealing clues to type II diabetes. The technique uses two-dimensional infrared spectroscopy and has potential applications in...
A recent RAND Corporation study reveals significant disparities in the quality of care received by women with heart disease and diabetes compared to men. Women were less likely to receive essential treatments for cholesterol management, chronic heart failure, and after a heart attack, despite having similar insurance coverage.
Researchers found that employees who participated in a workplace health program improved their blood pressure control and diabetes management, with significant reductions in absenteeism and workplace accidents. The program's comprehensive wellness system, which included coaching, incentives, and health screenings, was key to its success.
Researchers at the University of Manchester have successfully treated diabetic patients with MRSA-contaminated foot ulcers using green bottle fly larvae. The study found that all but one patient were cured within three weeks, significantly shorter than conventional treatment.
Dr. Frances M. Ashcroft's research discovered a rare genetic form of diabetes, permanent neonatal diabetes mellitus, and developed a treatment allowing children to switch from daily insulin injections to a daily pill. The American Physiological Society presented her with the Walter B. Cannon Award.
A new study suggests that antibiotic therapy for diabetic foot infections can be predicted using specific laboratory and clinical tests. The study found that deep wounds or high white blood cell counts significantly increased the risk of bad outcomes.
A recent study by Dr Yin Paradies and colleagues reveals that indigenous people do not have a genetic predisposition to diabetes. The research shows that social factors such as poor diet, reduced physical activity, stress, and low birth weight contribute significantly to the high rates of diabetes among indigenous populations.
The study analyzed existing genetic studies and found that non-genetic factors such as poverty, housing segregation, and poor diet are stronger indicators of diabetes than genes. The findings challenge the widely held thrifty genotype theory, which suggests that certain minority groups are genetically prone to diabetes.
The new guidelines recommend measuring waist circumference in all adults to assess risk of cardiovascular disease and diabetes. Health professionals are advised to incorporate this measurement into their toolkit for managing overweight and obese patients.
LCT reports a major breakthrough in islet transplantation, with a human patient showing evidence of live porcine islet cells and insulin production ten years after the transplant. The study demonstrates the long-term safety and viability of LCT's encapsulated porcine islets without immunosuppression.
A new study reveals that diabetes causes erectile dysfunction by affecting the brain's nitric oxide mechanisms. The researchers found that restoring nitric oxide production in the brain can alleviate erectile dysfunction in diabetic rats.
An estimated 60 million American adults are at high risk of vision loss due to various factors such as age, diabetes, and income level. Only half of the high-risk population visited an eye doctor in the past year, emphasizing the need for better access to preventive eye care services.
A recent study by Joslin researchers has identified the glucose transporter 2 (Glut2) protein as a key contributor to the development of birth defects in children born to mothers with diabetes. Glut2 enables high blood glucose levels to enter embryonic cells, increasing the risk of malformations.
A national series of interventions aimed at improving chronic disease management quality resulted in enhanced processes of care for diabetes, asthma, and hypertension. However, these efforts did not lead to improvements in intermediate clinical outcomes, such as control of high blood pressure or glycated hemoglobin levels.
The number of people with diabetes has increased substantially, making it one of the most costly chronic diseases. Researchers found a 69% rise in diabetes prevalence in Ontario, Canada from 1995 to 2005, exceeding global predictions for 2030.
A diet rich in black soya beans could help control weight, lower fat and cholesterol levels, and aid in the prevention of diabetes. The soya protein may be having an effect on fat metabolism in the liver and adipose tissue, reducing synthesis of new fatty acids and cholesterol.
A case study reports a 36-year-old bodybuilder developing diabetes after using growth hormone and anabolic steroids for extended periods. Regular blood sugar checks are urged for individuals taking high doses of growth hormone to prevent similar cases.
Spring Point Project's biosecure animal facility has successfully bred high-health, pathogen-free pigs, paving the way for potential human islet cell transplantation. The goal is to provide an FDA-approved standard treatment soon after clinical trials within three years.
A new study reveals Pycnogenol, a French maritime pine tree extract, is 190 times more potent in delaying glucose absorption than prescription medication Precose. This natural extract has been shown to suppress carbohydrate absorption in diabetes, making it an effective alternative for managing type 2 diabetes.
Researchers found that surgically removing the vagus nerve in mice prevented or reversed insulin resistance and high blood pressure. The study suggests altering vagal nerve activity could provide a novel treatment approach for diabetes and hypertension.
A study by Johns Hopkins Bloomberg School of Public Health reveals that 18% of American men experience erectile dysfunction, with age being a major risk factor. Lifestyle changes such as increased physical activity and disease prevention measures may also improve male sexual function.
A nationally representative survey of 1,022 adults found that 69 percent would prefer a dietary approach to treating diabetes, while just 21 percent preferred medication. The survey results support clinical research findings on the effectiveness of low-fat vegetarian diets in controlling and reversing diabetes.
A Joslin Diabetes Center-led team identified a group of proteins that may play critical roles in causing blood vessel leakage in the eyes of people with diabetic retinopathy. One of these molecules causes retinal blood vessel leakage, contributing to swelling and vision loss.
A recent study by Saint Louis University researcher Edward Weiss found that about half of Americans have a version of the FABP2 gene that affects fat metabolism, increasing their risk of developing diabetes. Lifestyle factors such as diet and exercise can help mitigate this risk.
Researchers at Rush University Medical Center found significant differences between antihypertensive drugs and their risk of new-onset diabetes. ACE-inhibitors and ARBs prevent diabetes, while diuretics and beta-blockers increase the risk. The study analyzed 22 long-term randomized clinical trials and included 143,153 patients.
Researchers found that antihypertensive agents ARBs and ACE inhibitors are the least associated with incident diabetes, followed by calcium-channel blockers and placebo. The study provides a systematic review of clinical trials and finds highly coherent estimates that are robust to sensitivity analyses.
Researchers found that replacing SH2B1 only in the brain of mice lacking it prevents obesity and diabetes. The study implicates SH2B1 as a potential target for treating obesity and type II diabetes.
A study published in JAMA found that South Asians have higher levels of heart attack risk factors, such as smoking and diabetes, at younger ages. The research suggests that lifestyle changes implemented early in life can reduce the risk of heart attacks in South Asians.
Researchers found a decline in allergic reactions to insulin, largely attributed to improved purification methods. New continuous subcutaneous insulin infusion (CSII) systems may help reduce these reactions even further.
A study found that liver transplant patients with a history of obesity, impaired fasting glucose, and hepatitis C infection are at increased risk of developing new-onset diabetes mellitus. The risk factors also include the use of certain immunosuppressants and cardiovascular risk factors.
Scientists have discovered a gene called 'Titch' that plays a key role in the metabolism of insulin in flies and may also be relevant to humans. The finding has implications for the development of new drugs for Type II diabetes.
A new hypothesis proposes that a deficiency in the enzyme Pancreatic Endoplasmic Reticulum Kinase (PERK) during fetal development can lead to permanent neonatal diabetes. The research found that PERK-deficient mice have impaired beta cell proliferation, differentiation, and clustering, resulting in reduced insulin production.
The increasing prevalence of metabolic syndrome, a state characterized by cardiovascular risk factors such as obesity and high blood pressure, is a growing concern. Physicians emphasize the need for aggressive treatment and lifestyle modifications to prevent serious health problems.
Primary Care Diabetes is an influential new journal launched in February 2007, covering clinical care, education, nutrition, health services, and psychosocial research related to diabetes. The journal aims to promote the implementation of evidence-based diabetes practices in primary care settings.
Researchers at NYU and Scripps have identified a new enzyme GAPDH that regulates insulin pathways, providing a promising direction for treating diabetes. The discovery of GAPDS, an inhibitor of GAPDH, attenuates diabetic symptoms in model animals, suggesting a potential therapeutic target.
A study by Group Health found that panic episodes in diabetic patients are linked to poorer health outcomes, including higher blood sugar levels and greater disability. The researchers also discovered that half of the patients with panic also had major depression.
Researchers have proven that tumours can be prevented from forming when embryonic stem cells are transplanted into laboratory animals. The team used microencapsulation technology to achieve this result, paving the way for vital therapies for disorders like diabetes.
A recent study found that high blood glucose is responsible for approximately 2.2 million cardiovascular deaths and 1.5 million ischaemic heart disease deaths worldwide. The findings highlight the significant burden of high blood glucose on mortality from these conditions.
A new study by Saint Louis University researcher Edward Weiss found that both diet and exercise provide significant benefits in reducing the risk of diabetes. The study, which followed 50-60 year olds with a high body mass index, showed improvements in glucose tolerance and insulin levels in all three groups, regardless of whether they...
Researchers at Northwestern University have discovered an enzyme called ACE2 that may hold the potential to treat diabetic kidney disease. Studies suggest that increasing ACE2 levels in the kidneys could reverse or prevent kidney disease from developing.
Research published in Phytotherapy Research found that silymarin extract can significantly lower fasting blood sugar levels and reduce glycosylated haemoglobin in patients with type II diabetes. The study showed promising results, but further large-scale trials are needed to confirm its effectiveness.
A new study from Harvard Medical School and Brown Medical School shows that racial disparities in care cannot be attributed to low-performing health plans. The research found that high-performing plans and low-performing plans have comparable levels of disparities in key health measures.
A study published in JAMA found that black patients in Medicare managed care health plans experience poorer treatment outcomes for common conditions like high blood pressure, diabetes, and high cholesterol. The disparity in quality of care was largely attributed to within-plan disparities rather than differences across health plans.
A new study published in PLoS Medicine found that older people with diabetes are at a higher risk of dying from cardiovascular disease, with the risk being particularly high for those treated with insulin injections. The study followed nearly 6000 individuals over 65 and found that approximately 50-60% of deaths were attributable to ca...