Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
Researchers found that activating a protein in muscle tissue increased average lifespan and prevented some age-related diseases in mice. The protein, uncoupling protein-1, converts energy from food into heat and mimics the effects of exercise.
A University of Missouri-Columbia study found that weight gain, not the type of diet, is a key factor in developing diabetes in cats. The researchers compared glucose-tolerance tests between cats fed dry food and those fed canned food, finding no significant difference.
Researchers at the University of Utah Health found that lung transplantation rarely extends children's survival and can even increase their risk of dying. The study analyzed data from 514 patients with cystic fibrosis and found that only one patient showed a clear benefit from transplantation, while others were at a higher risk of death.
Scientists at the University of Pennsylvania School of Medicine have found a protein called Rev-erb that coordinates the body's daily oxygen cycle to maintain correct metabolism. This discovery provides new pathways for treating metabolic disorders like obesity and diabetes.
A new study finds that 92% of older adults with diabetes have at least one other major chronic condition, and nearly half have three or more. The severity and type of co-existing condition matter, decreasing patients' ability to manage their diabetes.
A new study found that dieters who eat in response to emotions, rather than social situations, tend to lose less weight and experience more weight regain. Emotional eating was associated with lower weight loss and higher likelihood of regaining weight in successful losers.
Researchers found that fasting was associated with lower odds of being diagnosed with coronary artery disease (CAD) in patients who fasted. Fasting was linked to healthier arteries, even in people with diabetes, although the study does not recommend skipping meals for diabetics.
The estimated prevalence of chronic kidney disease in US adults has increased from 10% to 13%, driven by rising diabetes and hypertension rates. The prevalence of earlier stages of CKD accounts for most individuals with the condition, highlighting the need for cardiovascular risk factor management.
Researchers at Mayo Clinic found no link between diabetes treatment and survival rates after a heart attack. The study, which analyzed data from over 2,700 patients, suggests that commonly used medications for managing blood sugar levels do not reduce the likelihood of survival after a heart attack.
Researchers at Stanford University School of Medicine have identified a protein called menin as a key regulator of gestational diabetes. The study suggests that understanding the mechanisms of regulating menin could lead to new ways of growing islets for transplantation and new treatments for diabetes in pregnant women and obese adults.
A study found HIV-infected African Americans are at a higher risk of developing end-stage renal disease (ESRD) than white patients with HIV, with rates similar to those with diabetes
A new UCLA study found that vulnerable elderly patients enrolled in Medicare and Medicaid received only 65% of recommended tests and treatments, indicating significant room for improvement. The study examined quality of care for common conditions such as depression, diabetes, hypertension, and heart failure.
Patients with severe psychiatric illness lose 25-30 years of life expectancy due to increased risk of cardiovascular disease, diabetes, heart disease, and stroke. Lifestyle interventions like healthy eating and exercise can be challenging for this population.
A recent study found that workers with diabetic neuropathic symptoms lose an average of 1.4 hours per week due to health-related lost productive time, resulting in $3.65 billion annual costs. Those with diabetes without symptoms still experience a higher likelihood of unemployment compared to their non-diabetic counterparts.
A recent study by researchers at the University of Chicago found that many diabetics experience a significant burden from managing their condition, which can be as impactful on quality of life as the disease itself. Patients reported being distressed by end-stage complications and disliked intensive treatments.
Most diabetes drug trials prioritize reducing blood sugar levels over patient-relevant outcomes like complication risk and quality of life. This can lead to ineffective treatments that cause more harm than good.
Middle-aged and older adults from African American and Latino backgrounds have poorer blood sugar control than their white counterparts, even when taking medications. The study identified medication adherence and emotional distress as key factors contributing to these disparities.
Scientists have discovered a new mechanism by which insulin-secreting cells regulate KATP channels, allowing for timely energy supply and storage of blood sugar. This discovery sheds light on how the human body maintains normal blood glucose levels and prevents diabetes.
A Kaiser Permanente study shows that treating gestational diabetes during pregnancy lowers a child's risk of becoming obese, with children whose moms were treated having the same risk as those with normal blood sugar levels. High maternal sugar levels increase childhood obesity risk, but treatment reduces it.
Researchers found high levels of reactive compounds in soda sweetened with high-fructose corn syrup, which may contribute to cell and tissue damage that could cause diabetes. Adding tea components like EGCG reduced the levels of these compounds.
A recent heart attack increases the risk of developing new-onset diabetes and pre-diabetes by up to four-and-a-half times. Lifestyle factors such as smoking cessation, weight loss, and adherence to a Mediterranean diet can substantially lower this risk.
A study found that morbidly obese mice can gain protection against diabetes by consuming excess calories without developing insulin resistance. The key hormone adiponectin plays a crucial role in this process, and its abundance helps store excess fat in the right places.
Severely obese patients who undergo gastric bypass surgery show significant reductions in mortality rates from coronary heart disease, cancer, and diabetes. The study found a 56% lower mortality rate from coronary heart disease, a 60% lower death rate from cancer, and a 92% lower death rate from diabetes.
Researchers at the University of Liverpool have identified a molecule in the intestine that can detect sugar content, which could lead to new treatments for diabetes and obesity. The sweet taste receptor is not only present in the tongue but also in the intestine, allowing it to monitor dietary sugars.
Patients with diabetes and acute coronary syndromes have a significantly higher risk of death at 30 days and one year compared to those without diabetes. The study found that diabetes increased the risk of death by nearly 80% at 30 days for patients with unstable angina/non-STEMI and 40% for those with STEMI.
Researchers found that sub-standard housing more than doubled diabetes risk among study participants. Despite ruling out other factors, housing conditions remain a significant contributor to the development of diabetes in this population.
A study found that fair or poor housing conditions increase the risk of developing diabetes in urban, middle-aged African-Americans. Housing conditions, such as cleanliness and physical condition, were evaluated to clarify the relationship between environment and health outcomes.
A RAND Corporation study reveals a sharp decline in undiagnosed diabetes cases among American men over the past 25 years, with ethnic disparities largely eliminated. The study also found that education levels play a significant role in diabetes diagnosis, with those having less education being less likely to receive accurate diagnoses.
Research reveals abnormal fat metabolism as a key factor in the development of heart disease among diabetics. Brief caloric restriction can lead to dramatic accumulation of triglycerides and cardiac hemodynamic dysfunction in transgenic myocardium expressing human calcium-independent phospholipase A2γ.
Women with diabetes lose protective effect of estrogen on kidneys, which normally reduces risk of chronic kidney disease. Research suggests that hormone ratio rather than absolute levels determines impact on diabetic kidney disease.
A new study from Northwestern University's Feinberg School of Medicine reveals that older people with inadequate health literacy had a 50 percent higher mortality rate over five years than those with adequate reading skills. Low health literacy was the top predictor of mortality after smoking, surpassing income and years of education.
A study published in Archives of Surgery found that diabetics spend more days in the intensive care unit and have more complications during hospitalization for trauma. Diabetics are also less likely to be discharged home and require skilled nursing care after discharge.
Researchers at McGill University Health Centre have identified a new gene involved in type 1 diabetes, bringing the total to five genes responsible for the disease. The discovery using high-density DNA microchip technology provides a promising step towards developing effective treatments and prevention methods.
A daily pint of milk reduces the risk of metabolic syndrome by 62%, while regular dairy consumption lowers the risk by 56%. The study found that around one in seven men had the syndrome at entry into the study, with those who consumed more dairy produce having a lower risk.
Research at Harvard Medical School found that uninsured adults before age 65 require more intensive and costlier care than those with private insurance. This can lead to costly complications and reduced health needs after age 65.
A new study found that patients treated with HCQ were less likely to develop diabetes, and those who did were more likely to manage their disease without medications. The medication may also be suitable for people at high risk of developing diabetes as a preventive therapy.
Research reveals nearly half of people with diabetes use alternative therapies, which can interact with conventional medications and affect blood sugar levels. Healthcare professionals must be included in discussions about these therapies to document their use and identify potential problems.
The study found that the death rate for men with diabetes declined by 43% between 1971 and 2000, while the death rate for women with diabetes did not change. The authors suggest that different approaches may be needed to improve health outcomes for women with diabetes.
A recent study from the University of Missouri-Columbia found that exercise alone led to significant improvements in blood glucose levels for people with diabetes, outperforming diet and medication changes. The meta-analysis of 10,455 subjects showed that physical activity had equal benefits across age groups and genders.
A study found that men and women with diabetes at age 50 and older have a significantly reduced life expectancy and fewer years without cardiovascular disease. This increase in risk of illness and death is attributed to the global prevalence of Western lifestyle habits, leading to an alarming rise in diabetes cases.
Recent falls in US coronary heart disease deaths can be attributed to a combination of lifestyle changes and medical therapies. Despite decreases in risk factors such as smoking and high cholesterol, increases in obesity and diabetes offset the progress.
Research found that smokers with diabetes received increased cessation advice since 2004's performance-related GP incentives. This led to reduced smoking rates among those with the condition, especially in disadvantaged groups.
A study in London found that introducing financial incentives for physicians improved support for smoking cessation and reduced smoking prevalence among people with diabetes who smoke. The introduction of pay-for-performance incentives has the potential to improve quality of care for these patients.
A new study published by Duke University Comprehensive Cancer Center found that patients with chronic illnesses like diabetes or heart disease are no more likely to receive an early cancer diagnosis due to frequent healthcare interactions. Screening is still crucial regardless of medical management.
A Mayo Clinic research team has developed a simple tool to enhance medication adherence in diabetes patients, with 84% of users showing improved compliance. The decision aid sparks conversation between doctors and patients about medication risks and benefits, leading to better-informed decisions.
A new University of Leicester study reveals that low levels of physical activity among inner city school children have reached epidemic proportions. Over 3500 pupils from five secondary schools were surveyed, with half spending over 4 hours daily watching TV or playing computer games.
A new study published in Diabetes Care identifies two critical factors that increase the risk of recurrent wounds in diabetics: the location under the big toe and poor blood flow. This information can help physicians predict and prevent complications, including gangrene and amputation.
A recent study has linked sleep apnea to a higher incidence of gestational diabetes and pregnancy-induced high blood pressure. The researchers analyzed data from over 4 million deliveries and found that women with sleep apnea were more likely to develop these conditions, particularly when their weight was taken into account.
Scientists at the University of Wisconsin-Madison have developed a powerful analytical tool capable of measuring molecular structures quickly and accurately, capturing intermediate steps of protein folding and revealing clues to type II diabetes. The technique uses two-dimensional infrared spectroscopy and has potential applications in...
A recent RAND Corporation study reveals significant disparities in the quality of care received by women with heart disease and diabetes compared to men. Women were less likely to receive essential treatments for cholesterol management, chronic heart failure, and after a heart attack, despite having similar insurance coverage.
Researchers found that employees who participated in a workplace health program improved their blood pressure control and diabetes management, with significant reductions in absenteeism and workplace accidents. The program's comprehensive wellness system, which included coaching, incentives, and health screenings, was key to its success.
Researchers at the University of Manchester have successfully treated diabetic patients with MRSA-contaminated foot ulcers using green bottle fly larvae. The study found that all but one patient were cured within three weeks, significantly shorter than conventional treatment.
Dr. Frances M. Ashcroft's research discovered a rare genetic form of diabetes, permanent neonatal diabetes mellitus, and developed a treatment allowing children to switch from daily insulin injections to a daily pill. The American Physiological Society presented her with the Walter B. Cannon Award.
A new study suggests that antibiotic therapy for diabetic foot infections can be predicted using specific laboratory and clinical tests. The study found that deep wounds or high white blood cell counts significantly increased the risk of bad outcomes.
The study analyzed existing genetic studies and found that non-genetic factors such as poverty, housing segregation, and poor diet are stronger indicators of diabetes than genes. The findings challenge the widely held thrifty genotype theory, which suggests that certain minority groups are genetically prone to diabetes.
A recent study by Dr Yin Paradies and colleagues reveals that indigenous people do not have a genetic predisposition to diabetes. The research shows that social factors such as poor diet, reduced physical activity, stress, and low birth weight contribute significantly to the high rates of diabetes among indigenous populations.
The new guidelines recommend measuring waist circumference in all adults to assess risk of cardiovascular disease and diabetes. Health professionals are advised to incorporate this measurement into their toolkit for managing overweight and obese patients.
LCT reports a major breakthrough in islet transplantation, with a human patient showing evidence of live porcine islet cells and insulin production ten years after the transplant. The study demonstrates the long-term safety and viability of LCT's encapsulated porcine islets without immunosuppression.
A new study reveals that diabetes causes erectile dysfunction by affecting the brain's nitric oxide mechanisms. The researchers found that restoring nitric oxide production in the brain can alleviate erectile dysfunction in diabetic rats.
An estimated 60 million American adults are at high risk of vision loss due to various factors such as age, diabetes, and income level. Only half of the high-risk population visited an eye doctor in the past year, emphasizing the need for better access to preventive eye care services.