Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
A recent study published in Archives of Surgery found that tightly controlled blood sugar levels before surgery can significantly reduce the risk of postoperative infections in diabetic patients. The research involved 490 diabetic patients who underwent major noncardiac surgery between 2000 and 2003, with 197 having good glycemic control.
Researchers discovered that p110 alpha controls insulin signals, frequently mutated in cancer, but mice with a single mutation showed no signs of developing diabetes. The findings have immediate implications for testing p110 alpha-specific inhibitors for human therapies.
Diabetic patients undergoing periodontal therapy show improved metabolic control, with a 20% reduction in HbA1c levels. The study suggests that periodontal treatment may help diabetic patients move from the 'at-risk' category to a healthy range.
In a study on Huntington disease, researchers found that cystamine increased brain levels of protective protein HSJ1b and BDNF, suggesting a promising candidate for treatment. The study also revealed that cystamine raises BDNF in an HSJ1b-dependent manner.
The University of Pittsburgh study found significant improvements in clinical, behavioral, and psychological indicators for patients receiving the chronic care model (CCM) intervention. Patients and providers received diabetes-control education, leading to better blood glucose control, HDL cholesterol, and diabetes knowledge.
A recent study by the American Heart Association found that people who slept for five or fewer hours per night were more likely to develop hypertension than those who slept seven or eight hours. This association was observed even after controlling for other risk factors, such as obesity and physical activity.
A recent study found that diabetes care has improved over the past decade, but two in five people with diabetes still have poor control of cholesterol and blood pressure. Lifestyle changes can significantly reduce the risk of heart disease for those with mild hypertension.
Research found that young pregnant women with pregnancy complications are at increased risk of heart disease and death, with the risk doubling after adjusting for medical factors. Smoking during pregnancy was also found to significantly increase the risk of all-cause death and cardiac death.
A recent study conducted by Dr. Charles Simonton and the STENT Group found that both drug-eluting stents performed well in controlling restenosis in diabetics, with paclitaxel-eluting stents potentially showing better outcomes for insulin-treated diabetic patients.
A survey of 2,461 diabetes patients found that many had a less-than-accurate view of healthy body weight. Women were more likely to correctly identify a normal BMI range as healthy, while men and obese individuals often overestimated their ideal weights.
A study found that feedback on performance given to primary care physicians decreased clinical inertia and improved glucose levels in their patients. The intervention, which included physican-specific feedback and computerized reminders, led to sustained improvements in physician behavior and patient outcomes after three years.
Researchers found that people with diabetes from different ethnic groups have varying levels of muscle mass in the left ventricle, a key indicator of heart health. In white, African-American, and Hispanic individuals, increased muscle mass was linked to subclinical atherosclerosis and high blood pressure.
A study found that older adults in North Carolina predominantly use food home remedies and other home remedies for health management, often as a form of self-care. The study also revealed significant differences in CAM therapy use among ethnic groups, with African-Americans and Native Americans showing higher rates of use.
A recent study published in Diabetes reveals that diabetes rates in the US have increased dramatically over the past decade, leading to a sharp rise in hospitalizations and deaths from coronary heart disease. As a result, progress made in reducing illnesses and deaths from this condition may be put at risk.
Lifelong calorie restraint is crucial for preventing excess weight and age-related health issues such as high blood pressure and diabetes. Studies with rhesus monkeys show that maintaining a constant healthy body weight can improve overall health and prolong lifespan.
Research highlights importance of early oral health screenings for young patients with diabetes, as gum disease onset is younger than previously recognized. Studies show significant disparities in dental care access and a perceived lack of need among diabetic patients.
A recent study published in the Canadian Medical Association Journal found a strong correlation between height and the risk of amputation among patients with diabetes mellitus. The research showed that every 10-cm increase in height was associated with a 16% higher risk of amputation, even among those with well-controlled diabetes.
A study by UF researchers reveals that diabetic patients' cells have difficulty repairing damaged blood vessels due to low nitric oxide levels. The team found a way to improve the cells' movement and repair ability using nitric oxide, opening up possibilities for new treatments.
Studies found that erectile dysfunction is common among men and associated with various chronic diseases, including heart disease. The condition was also linked to increased risk of future cardiovascular events, diabetes, and hypertension.
Researchers found that therapies targeting brain insulin receptors can significantly improve blood sugar control and reduce insulin dose requirements. Gene therapy interventions also increased the animals' response to insulin therapy about 2-fold.
A Northwestern University study found that middle-aged individuals with higher body mass indexes had significantly higher risks of hospitalizations for and deaths from heart disease and diabetes in older age. Having a normal BMI in young adulthood and middle age confers significant health benefits.
The new JBS 2 guidelines focus on cardiovascular disease as a whole, including those with hardened arteries and diabetes. Screening is recommended for adults at high risk of cardiovascular disease, with targets set for blood pressure, cholesterol, and sugar levels.
The Joslin Diabetes Center study found that online discussion boards provide a less threatening way to discuss sensitive concerns about diabetes. The study, which tracked over 330,000 visits to the discussion boards, found that nearly 75% of respondents rated participation as having a positive effect on coping with diabetes.
Two landmark papers unveiled significant breakthroughs in preventing amputations in diabetes patients. Novel Negative Pressure Wound Therapy technology has been shown to simplify complex wounds, while powerful antibiotics have demonstrated comparable efficacy when administered once daily.
A survey found that nearly half of people with diabetes are not using aspirin as prescribed, despite its proven benefits in reducing heart attack and stroke risk. The study highlights the need for better communication between healthcare professionals and patients, particularly those with diabetes who are at higher risk.
A population study of over 3,000 adults found that hostility does not affect long-term heart health in women, unlike men. Men with high hostility scores were twice as likely to experience recurrent heart disease events.
A study identified measurable differences in the skin of diabetes patients, particularly those with peripheral neuropathy, before ulcerative foot disease develops. The findings also showed reduced energy reserves in foot muscles, highlighting microcirculatory changes as a major factor.
Researchers found that people with diabetes are 1.4 times more likely to develop colon cancer compared to those without the condition. The study analyzed data from a nationally representative sample of patients and controlled for various factors, including age and obesity.
A randomized controlled study showed a significant reduction in systolic blood pressure (SBP) of 7.4 mmHg in the treatment group, compared to a rise of 3.1 mmHg in the control group. The device also demonstrated a dose-response relationship, with increased breathing exercise sessions resulting in greater SBP reduction.
A Columbia University study shows that aprotinin decreases blood glucose levels and insulin resistance in diabetic patients undergoing CABG surgery, reducing the risk of complications. The study's findings have important implications for the management of blood glucose levels during heart surgery.
A study by Fox Chase Cancer Center found no significant impact of type II diabetes on the initial profile or treatment outcomes of prostate cancer. However, men with type II diabetes experienced significantly worse long-term overall survival rates compared to those without diabetes.
Three patients underwent gastric bypass surgery and developed severe hypoglycemia, requiring partial or complete pancreas removal. Abnormal insulin-producing islet cell proliferation was found in all cases.
A study of 906 breast cancer patients found that comorbidities such as diabetes and hypertension contributed to racial disparities in survival rates. Black patients had shorter overall survival rates, while whites were more likely to die from competing causes.
US kidney failure rates have stabilized over the past two decades, with diabetes and high blood pressure remaining leading causes. Despite progress, racial disparities persist, particularly among African Americans, who continue to experience higher rates of new cases.
The PROactive study found that Takeda's ACTOS (pioglitazone HCl) significantly reduced the combined risk of non-fatal heart attacks, strokes, and deaths by 16% in high-risk patients with type-2 diabetes. This led to a 10% reduction in the primary combination endpoint of seven different macrovascular events.
Researchers at Mayo Clinic found nerve damage due to high blood sugar levels can begin as early as 20 years into the disease. The study of over 500 patients showed steady worsening of nerve conduction tests even in those with normal values, highlighting the importance of controlling diabetes from onset.
Researchers have identified a potential new treatment for insulin-dependent diabetes by targeting natural killer T cells. The study shows that multiple doses of alpha-galactosylceramide can reduce the production of interferon-gamma, which helps destroy transplanted islet cells.
Researchers found that smokers had a significantly higher incidence of developing diabetes compared to non-smokers, even after adjusting for other risk factors. The study suggests another poor health outcome associated with cigarette smoking, supporting current surgeon general's warnings.
High insulin levels block stress hormones, leading to excessive fat storage and energy imbalance. The study provides new understanding of insulin resistance in Type II diabetes and its potential link to obesity.
A study of over 16,000 participants found a graded association between high blood glucose levels and increasing coronary heart disease risk. Non-diabetic individuals with elevated HbA1c levels were at significantly increased risk of heart disease.
The partnership aims to stimulate and accelerate European research into beta cell function and survival, aiming to move towards a cure for diabetes. Approximately 194 million people worldwide suffer from diabetes, with the number expected to exceed 333 million by 2025.
A diet high in soy protein prevents the accumulation of triglycerides and cholesterol in the liver despite obesity and hyperinsulinemia. This is achieved through reduced expression of genes involved in lipid production and increased breakdown of fatty acids.
Researchers have discovered that malfunctioning bone marrow cells can cause premature cell death and dysfunction in nerve cells, leading to neuropathy. The study provides a basis for understanding the dangerous nerve condition in diabetics and may eventually lead to a treatment.
A recent study found that diabetics who underwent ankle fracture surgery had significantly longer hospital stays and higher mortality rates compared to non-diabetic patients. The researchers estimated that diabetic patients experienced an additional day of hospitalization and costs approximately 20% higher.
Only about 0.06% of health plan members receive a diagnosis for alcohol dependence, compared to 40% for depression, 65% for diabetics, and 70% for those with hypertension. This failure to identify and treat alcohol dependence begins with inadequate screening and follow-up care.
A study found that insulin resistance is a predictor of congestive heart failure (CHF) in elderly men, independent of diabetes and other established risk factors. Insulin resistance was also associated with more severe disease and a worse prognosis in patients with CHF.
A national survey reveals that many Americans take high doses of vitamin E supplements, despite potential risks, and a study shows that test results are frequently forgotten after hospital discharge. A new study suggests that full coverage for ACE inhibitors would improve health outcomes and save Medicare money.
A new study suggests that ACE inhibitors, which reduce blood pressure and prevent diabetes-related complications, should be made available at no cost to seniors with diabetes. This could lead to increased use of the medication and significant savings for Medicare, with estimates suggesting $1,606 in lifetime savings per recipient.
A recent study published in Archives of Internal Medicine found diuretics to be equally protective against fatal coronary heart disease or non-fatal heart attacks among people with diabetes. Additionally, diuretics were shown to be more effective in lowering systolic blood pressure and reducing the risk of congestive heart failure.
A new study suggests that minor surgery plus antibiotics can prevent foot-bone infections and amputations. Patients with diabetes are at high risk, especially those with poor circulation and kidney problems.
A new study published in New England Journal of Medicine shows that treatment for mild gestational diabetes reduces maternal glucose levels and improves health outcomes for both mothers and babies. The ACHOIS trial, the largest of its kind, recruited 1000 women and 1030 babies from Australia and the UK.
A Joslin study finds that maintaining a controlled diet and preventing weight gain can prevent the development of glucose intolerance in individuals born with low birth weight. The researchers observed improved insulin sensitivity and reduced risk of diabetes in mice on calorie-restricted diets compared to those allowed to eat freely.
A study of 36 studies found that minority populations received fewer preventive care measures for diabetes, including flu vaccinations and cholesterol tests. Socioeconomic factors, language differences, and potential bias in healthcare may contribute to these disparities.
A Harvard study finds that diabetics experience impaired blood vessel function on days with high sulfate and black carbon particle pollution, increasing heart attack risk. The research highlights a biological mechanism linking particle pollution to cardiovascular disease.
A study by researchers at Duke University Medical Center found that improved disease knowledge alone does not translate into improved blood sugar control, cholesterol levels, weight management, or mortality rates among diabetics. Despite this, education is still an important aspect of diabetes care.
Researchers found that exposure to fine particles in air pollution impairs blood vessel reactivity in people with diabetes, leading to a higher risk of heart problems. The study also suggests that this association may help explain previous findings on the link between air pollution and cardiovascular issues in diabetics.
Research found a strong association between depression severity and poor glycemic control among Hispanics with diabetes, particularly those with moderate-severe depression. This underlines the importance of identifying and treating depression to improve diabetic outcomes in this high-risk population.
Researchers at Cedars-Sinai Medical Center found that patients with metabolic syndrome and moderate coronary calcium have a greater chance of having blockage in their arteries. The study analyzed 1,043 patients without known heart disease and found that those with metabolic syndrome had a significantly higher risk of ischemia during st...
Researchers analyzed voting patterns and committee memberships to find the most partisan committees, including the Select Committee on Homeland Security. They also developed a mathematical tool to identify Representatives' partisanship and cooperativity. Additionally, they created insulin-producing cells from human liver cells that can...
Researchers found that non-dippers had higher fasting glucose levels and were more likely to develop diabetes. Monitoring glucose levels is crucial for these patients to prevent cardiovascular problems.