Research on the causes and treatment of heart disease. Covers light exposure and heart health, sex differences, heart-in-a-dish models, and cardiac risk.
A recent study proposes a multi-dimensional approach to map disease relationships using genomic, chemical, and clinical data. The research reveals significant distinctions from the classical International Classification of Diseases system and highlights potential links between previously separate conditions.
Researchers found that men with a higher proportion of blood cells missing the Y chromosome have a higher risk of dying from heart failure. Elevated Y chromosome loss is associated with decreased treatment response in patients with transthyretin cardiac amyloidosis, a progressive disease causing heart failure and death.
Researchers at the Lewis Katz School of Medicine will investigate how injured heart cells communicate with other cells throughout the body using microvesicles known as exosomes. The study aims to understand how specific molecules, such as microRNAs, facilitate communication pathways between cells in the heart and vasculature.
Researchers discovered a step-by-step process of calcification in aortic valves, revealing two defense mechanisms: osteopontin and collagen fibers. The study provides new insights into understanding cardiovascular calcification and potential therapeutic applications.
A study of over 4,500 healthy adults aged 60 and older found that nearly 28% had some form of heart valve disease, with age being the main risk factor. The majority of cases were mild, but the study highlights the need for more research into screening methods to identify and manage the disease in the elderly population.
A Canadian Journal of Cardiology review article finds that plant-based meat alternatives tend to reflect a heart-healthy dietary pattern, improving cholesterol levels and blood pressure. The authors recommend incorporating PBMAs into a healthy diet as an excellent protein source, with options lower in saturated fat and sodium.
A new global definition of sarcopenia is proposed, aiming to unify research and clinical practice. The definition may help identify low muscle mass or strength in older people, increasing the risk of poor outcomes such as fragility and disability.
Researchers from PSI and ETH Zurich studied connexin-36 gap junction channels and found that antimalarial drug mefloquine binds to the channels, potentially explaining its severe side effects. The study provides new insights into how drugs interact with connexins and may lead to the development of therapies for neurological diseases.
Research highlights need for prevention and treatment approaches for children with obesity born underweight, finding links between low birth weight and cardiometabolic disease risks. Visceral fat storage issues contribute to type 2 diabetes risk.
Researchers develop a model of heart disease by tricking stem cells to behave like mature heart cells with a mutation that causes hypertrophic cardiomyopathy. The study reveals the connection between mechanical stress and electrical function in hearts, shedding light on why genetic mutations can cause arrhythmias.
Researchers found that hospitals that implemented standardized protocols from the American Heart Association and American Stroke Association saw significant reductions in stroke treatment times. The protocols, which include specific limits on time between symptom onset and hospital arrival, helped medical teams respond more quickly to ...
New research from Edith Cowan University found that dietary nitrate may play a role in preventing cardiovascular disease, dementia, and diabetes. Moderate to high intakes of plant and vegetable sourced nitrate were associated with a lower risk of all-cause, CVD-related, and cancer-related mortality.
Researchers created an integrated cellular map of a mouse model heart, pinpointing cells and pathways involved in fibrosis. The study identified myofibroblasts as the major drivers of scarring, but also discovered a 'matrifibrocyte' form that may prevent scar resolution.
A wearable health monitor developed by Washington State University researchers can accurately measure levels of important biochemicals in sweat during physical exercise. The device has the potential to track health conditions and diagnose common diseases, including diabetes, gout, kidney disease, and heart disease.
A new study found that regular snoring is associated with elevated blood pressure and uncontrolled hypertension, particularly in overweight middle-aged men. The research used multiple night home-based monitoring technologies and objective assessments to explore the connection between snoring and hypertension.
Research published in the European Heart Journal found that women diagnosed with perinatal depression are more likely to develop cardiovascular disease. The study included data from around 600,000 women and found a strong link between perinatal depression and risks of high blood pressure, ischemic heart disease, and heart failure.
Researchers developed a computational method to estimate sudden cardiac death risk using one-minute heart rate measurements at rest. The new method provides a significantly better estimate than previous analyses, identifying differences in heart rate intervals between high-risk and healthy patients.
Researchers developed a metabolic health score based on clinical parameters and used it to explore its genetic underpinnings in mice, validating findings in human data. The study identified two significant genetic regions linked to metabolic health and pinpointed candidate genes associated with metabolic traits.
A new risk equation could lead to a significant reduction in statin prescriptions, with 28.3 million adults potentially eligible instead of 45.4 million under current guidelines. The PREVENT equations incorporate recent insights into the biology of cardiovascular disease and remove race as a factor.
A University of Houston researcher has made a breakthrough discovery about the development of the heart in the womb, revealing that a certain gene deletion can cause a common type of heart muscle disease called left ventricular non-compaction.
Researchers developed a novel radiotracer that generates high-quality images of cardiac amyloidosis, a condition referred to as the Alzheimer's disease of the heart. The technetium-99m labeled variant of the pan-amyloid reactive peptide p5+14 showed significant uptake in patients with amyloid cardiomyopathy.
A study published in Heart Rhythm examined the potential dangers of energy drink consumption in patients with genetic heart diseases. The research found a temporal relationship between energy drink consumption and sudden cardiac arrest events, but caution is advised due to the small relative risk.
A substantial portion of young athletes are at risk of hypertension, with 21.3% meeting pre-HTN criteria and 8% diagnosed with Stage II HTN. Lifestyle interventions and screening for hypertension are crucial to prevent long-term health complications.
A recent study highlights the significant impact of rheumatic heart disease on adults' lives, with mortality rates being substantially reduced through valve surgery and valvuloplasty. The findings underscore the need to improve access to surgical and interventional care for these patients.
Research from the University of Illinois has found a link between per- and polyfluoroalkyl substances (PFAS) and cardiovascular diseases in postmenopausal women. The study reveals how PFAS chemicals interact with pro-inflammatory pathways, providing potential explanations for the increased risk.
Researchers found that eating more than one gram of sodium per day increases the likelihood of eczema flares by 22%, making it easier for patients to manage their symptoms. Eczema affects over 31 million people in the US and can be difficult to cope with when unpredictable.
By 2050, at least 61% of US adults (184 million people) are projected to have some type of cardiovascular disease, with total costs tripling to $1.8 trillion. Population shifts, high blood pressure, and obesity will drive this increase.
A new study found that people exposed to higher levels of airplane noise were more likely to have a higher body mass index, an indicator for obesity that can lead to cardiometabolic diseases. The study highlights the role of environmental factors in shaping health outcomes.
Researchers established a novel mouse model of inherited arrhythmia that spontaneously causes lethal arrhythmias, shedding light on the pathogenesis and potential drug efficacy. The study identifies a critical mutation in ryanodine receptor 2 (RyR2) as a key regulator of cardiomyocyte contraction.
A new study found that higher lifestyle scores associated with better heart health can lead to a younger biological age and lower risk of heart disease and stroke. The study used DNA methylation levels as a biomarker to estimate biological age.
The study identified specific patterns in blood samples of patients who had different clinical outcomes after a heart attack. These patterns, known as 'immune signatures', are associated with either better or worse recovery of heart function. The findings could lead to the development of new diagnostics and treatments for heart failure.
Researchers at CU Anschutz Medical Campus identified key elements to improve diagnosis and treatment of coronary heart disease (CHD) in women, addressing the common misdiagnosis of heart attacks. The new guidelines provide recommendations to help clinicians better address sex-specific symptoms and treatments.
The conference will feature 12 late-breaking clinical trials and science presentations on transcatheter aortic valve replacement, mitral and tricuspid devices and techniques. Data from these trials will guide the selection of patients who will benefit most from procedures and define optimal treatment strategies.
Researchers are exploring the connection between high-fat diets and Type 2 diabetes, with a focus on the REDD1 protein in heart cells. Insulin resistance in heart cells doubles the risk of heart failure and death, highlighting the need for new treatments for diabetic heart disease.
A new study has improved the detection of heart failure in women, allowing for earlier diagnosis and potentially life-saving treatment. The research used magnetic resonance imaging to fine-tune how pressures inside the heart are measured, increasing accuracy by 16.5% for female patients.
A Rutgers University study of over 31 million hospital records found that infertility treatment patients were twice as likely to be hospitalized with heart disease in the year after delivery. The study suggests that early postpartum checkups are crucial for patients undergoing infertility treatment.
A recent Finnish study discovered that high levels of sedentary behavior and low physical activity in children are associated with a higher cardiac workload and increased risk of heart disease in adolescence. Regular moderate to vigorous physical activity from childhood can help prevent these issues.
Researchers found associations between inflammatory and metabolic biomarkers and accelerated aging, with GlycA and GrimAge showing robust correlations. The study provides insight into the relationship between aging and cardiometabolic health, potentially informing vulnerable populations.
Jeffrey W. Moses, MD, is recognized for advancing the field of interventional cardiovascular medicine through technical excellence and leadership. Dr. Moses has performed over 20,000 interventional procedures and made significant contributions to clinical research and educational activities in interventional vascular therapy.
A new study found that brief anger episodes can negatively impact blood vessel function, leading to increased risk of heart disease and stroke. The researchers investigated the effects of anger, sadness, and anxiety on blood vessel function and found that evoking an angered state led to blood vessel dysfunction.
Researchers found that over 130,000 people in Denmark live with atrial fibrillation, with a 20% increase in new cases each year. The study reveals heart failure is the most common complication, with a risk of death twice as high as stroke after diagnosis.
Researchers designed a new AI model that accurately predicts treatment outcomes for stroke prevention in people with heart disease. The model, called CURE, was trained on a massive dataset of de-identified patient information and fine-tuned to focus on specific health conditions and treatments.
Researchers at the University of Missouri have developed a soft, self-charging material that can track vital signs like blood pressure and heart activity wirelessly. This innovation has significant implications for early disease detection and timely interventions in chronic conditions.
Robert A. Harrington, MD, will be honored for his groundbreaking work in clinical research and clinical excellence. He has made extraordinary contributions to the field of interventional cardiology, transforming cardiovascular care through his pioneering research and mentorship.
A recent study published in BJSM found that increased cardio fitness level can reduce the risk of death from any cause and heart disease by 11-17% and 18%, respectively. Regular aerobic exercise programs can achieve this, leading to a reduced risk of early death and chronic conditions.
A combined mechanical heart pump and gene-edited pig kidney transplant has given new hope to a patient with heart and kidney failure. The surgery was performed in two stages, first implanting the heart pump and later transplanting the gene-edited pig kidney. This innovative approach has shown promise for patients who would otherwise no...
Researchers found that spinal cord injury triggers abnormal neuronal activity that causes abdominal fat tissue compounds to leak and pool in the liver and other organs. A short course of gabapentin, commonly prescribed for nerve pain, prevented this damaging metabolic effect.
Researchers built more accurate cardiovascular risk models using machine learning, finding that women are underdiagnosed due to sex-neutral criteria. The study used the UK Biobank dataset and found that electrocardiogram (EKG) tests were most effective in improving detection of cardiovascular disease in both men and women.
The American Association for Thoracic Surgery (AATS) and Cardiovascular Research Foundation (CRF) will collaborate on the development of New York Valves 2024, focusing on advances in surgical approaches and techniques in valve disease. The summit will feature expert discussions, live-case demonstrations, and hands-on training.
Significantly reducing trans fat levels in the Nigerian food supply can prevent approximately 67,000 cases of heart disease within ten years. The policy also generates net savings, with total healthcare savings estimated at around $520 million over a population's lifetime.
A new study published in JNCI Cancer Spectrum found that following a healthy diet, such as the DASH diet, lowers the risk of cardiovascular disease in breast cancer survivors. Women whose diets were most similar to DASH had a 47% lower risk of heart failure and other cardiovascular-related events.
A new study from Israel found that nearly 1 in 5 adults with congenital heart disease developed an abnormal heart rhythm during a five-year study. Those who developed arrhythmias had twice the risk of early death and increased hospitalization rates compared to those without irregular heart rhythms.
A new American Heart Association Scientific Statement highlights the importance of patient-centered care in cardiovascular health, combining expert knowledge with consideration of patients' beliefs, preferences, and values. The statement provides practical guidance on incorporating person-centered care into routine clinical practice.
The updated Fitness to Drive Guidelines recommend driving restrictions for individuals with seven cardiac conditions, including active coronary artery disease and implantable devices. These guidelines aim to support physicians in advising patients on safe driving practices.
Researchers found that revascularization treatment significantly improves the quality of life for patients with chronic limb-threatening ischemia, a severe form of peripheral artery disease. The study revealed diminished quality of life among these patients, but revascularization restored sufficient blood flow and improved wellbeing.
Researchers at Columbia University developed BeatProfiler, an AI-based software that automates the analysis of heart cell function from video data, significantly speeding up the process and reducing errors. The tool can accurately analyze cardiomyocyte function, outperforming existing tools by being faster and more reliable.
Researchers developed a new method to detect heart failure using smartphones by analyzing heart movement. The technology has been shown to be accurate in identifying patients with heart failure, offering potential benefits for remote monitoring and treatment.
New York Valves: The Structural Heart Summit is a world-class educational experience for the field of structural heart interventions. The summit will showcase advanced techniques, evidence-based medicine, and live-case demonstrations, offering attendees an unparalleled opportunity to explore the newest techniques and technologies.
A study led by Michigan Medicine found that around 10% of deaths following percutaneous coronary intervention are potentially preventable. Complications during procedures contributed to 20% of the nearly 1,200 deaths reported during the study period.
A new study reveals that cardiovascular benefits were only experienced by higher-income populations, while lower-income groups saw stagnant or worsening health risks. The study suggests that improving access to healthcare and social determinants of health is crucial for addressing these inequalities.