Research on the causes and treatment of heart disease. Covers light exposure and heart health, sex differences, heart-in-a-dish models, and cardiac risk.
A new study identified USP5 as an enzyme crucial for breaking down unneeded or damaged proteins in the heart. Low levels of USP5 lead to protein buildup, triggering dilated cardiomyopathy in animal models. Increasing USP5 levels helps clear protein 'junk', improving heart function and reducing disease progression.
Researchers at FAU's Schmidt College of Medicine will explore the use of genetically engineered cells to treat degenerative diseases, with a focus on understanding how hypoxic conditions drive cellular transformation. The study aims to identify novel pathways controlling this process and develop strategies for engineering more complex ...
Women who experience late-onset menopause have significantly better vascular health and are less likely to develop heart disease than those who experience it earlier. The study found that preserved mitochondrial function and certain lipid levels in their blood may contribute to this protection.
Cardiac arrhythmia disrupts heart rhythm due to malfunctioning electrical impulses. Rui Zhu plans to use deep-learning and computational simulations to model diseased hearts and understand multi-physical factors contributing to arrhythmic conditions.
ApoB100 protein structure revealed for the first time, allowing for more precise testing and treatment of high cholesterol and heart disease. The discovery may lead to new drugs targeting LDL particles, reducing side effects of statin drugs.
Research reveals East Asian adults have greater risk of elevated iron stores, increasing the likelihood of heart disease, Type 2 diabetes, and liver disease. Genetic influences suggest a need for tailored dietary guidelines to prevent iron-related toxicity.
Research found that mothers of twins are twice as likely to be hospitalised with cardiovascular disease compared to singleton births. Those with twins and high blood pressure during pregnancy are at highest risk. However, deaths from heart disease decrease in mothers of twins compared to singletons over time.
Researchers at Lancaster University have developed a new method to detect Alzheimer's disease by analyzing changes in brain oxygenation dynamics and neuronal function. The study found that individuals with Alzheimer's disease exhibit altered respiratory frequency, which may be an early indicator of the condition.
The Red Dress Collection Concert marked the start of American Heart Month with a powerful celebration in New York City. The event, hosted by Sharon Stone, featured musical performances by Sara Bareilles and Suki Waterhouse and showcased red ensembles created by fashion's brightest talents.
The American Heart Association teamed up with 20 influential creators to launch American Heart Month and raise awareness about heart health. The event empowered audiences with knowledge about prevention while encouraging donations to support the Association's lifesaving mission.
A preliminary study found that shorter protective caps at the end of chromosomes (telomeres) may be more likely to develop age-related brain diseases such as stroke, dementia, and late-life depression. Adopting healthier lifestyles could lower the negative effects of shorter telomeres.
Two organizations, a health monitor developer and an addiction recovery platform creator, are honored for their innovative work supporting equitable health outcomes. The recognition highlights the importance of addressing social and economic barriers to cardiovascular disease.
The NFL and American Heart Association partner for the NFL PLAY 60 Fitness Break broadcast series, promoting physical activity in elementary schools ahead of Super Bowl LIX. The broadcasts feature exercises and drills to help kids meet the recommended 60 minutes of moderate-to-vigorous physical activity daily.
A new study from University of Florida researchers finds that heatstroke can lead to lasting, multi-organ damage and obesity in mice for months afterward. The animals' hearts metabolically crashed two weeks after the initial injury, leading to chronic deterioration and weight gain.
The study discovered new microbial species and never-before-reported metagenomes from African sites, shedding light on the importance of geography in shaping microbiome differences. The research highlights the need for site- and region-specific approaches to gut health interventions.
The American Heart Association's 2025 statistics report shows an increase of over 10,000 cardiovascular disease-related deaths in the US, with a slight decrease in age-adjusted death rates. Rising kidney disease, hypertension, and obesity are contributing to these trends.
The summit features live case demonstrations, interactive debates, hands-on training, and the latest evidence-based practices in structural heart care. Attendees will witness innovation in action, exploring breakthroughs in surgical techniques, transcatheter interventions, and personalized treatment strategies.
Researchers found that new habits can begin forming within about two months, but can take up to 335 days to establish. The study also identified factors that influence successful habit formation, including frequency, timing, and enjoyment.
American Heart Association awards Marcus Freeman with its top college football coaching honor, recognizing his 14-2 season with Notre Dame and efforts off the field to promote heart health. The award is part of a broader program that raises funds and awareness for cardiovascular disease.
Researchers found that brief ozone exposure reduces blood oxygen saturation, triggers hypoxia-related biomarkers, and increases arterial stiffness. Ozone pollution is a worldwide health issue, linked to increased risk of cardiovascular diseases.
A national survey of 1,008 Americans found that nearly two-thirds use a device to monitor their heart health, but only one in four shares the data with their doctor. This lack of sharing can lead to delayed diagnosis and treatment, emphasizing the importance of proactive communication between patients and healthcare providers.
Research published in the European Heart Journal found that people with high amounts of intermuscular fat are more likely to develop coronary microvascular dysfunction and future serious heart disease. The study's lead author suggests that existing measures of obesity may not be accurate for all individuals, particularly women.
A Michigan Medicine study suggests that higher out-of-pocket costs for initial cardiac rehabilitation sessions are a major barrier to participation. Patients who shared the cost of their first session attended more sessions than those who paid nothing, but still had lower odds of completing over 24 sessions.
Exposure to air pollution during the three months before pregnancy is associated with higher childhood obesity risk up to two years after birth. The study found that women with higher levels of PM2.5 and PM10 had children with a higher BMI and related obesity risk factors.
University of Birmingham researchers have been awarded a grant to study the mechanisms driving early cardiac dysfunction in CKD. The study aims to identify interventions that can reverse or prevent heart disease in its earliest stages.
Corey Bentley, a Bay Area community leader, was named the American Heart Association's 2024 National Leader of Impact winner. He raised over $300,000 and educated colleagues on Hands-Only CPR, benefiting 80+ people.
A new UC San Francisco study found that most 11- and 12-year-olds use TikTok and other social media platforms against the rules, showing signs of addiction. The study also revealed a quarter of children reported elements of addiction while using social media, linked to depression, eating disorders, ADHD, and disruptive behaviors.
A recent study published by Dr. Matthew Nystoriak of Masonic Medical Research Institute has uncovered groundbreaking insights into heart health. Elevated levels of β-hydroxybutyrate, a ketone body produced by the liver, have been shown to improve cardiac blood flow and reduce ischemic heart disease.
A new study from Tufts University estimates that sugary drinks contribute to 2.2 million new type 2 diabetes cases and 1.2 million new cardiovascular disease cases annually worldwide. Regular consumption leads to weight gain, insulin resistance, and metabolic issues tied to these diseases.
A new study reveals the COVID-19 pandemic led to a sharp decline in hospital visits for acute coronary syndrome, particularly among older adults and women. The research emphasizes the need for targeted interventions to ensure access to critical care during future emergencies.
A study led by Henry J. Pownall and Khurram Nasir found a strong link between the amount of free cholesterol in HDL and its accumulation in macrophages, which can contribute to heart disease. The researchers aim to develop new diagnostics and treatments for managing heart disease using HDL-free cholesterol as a biomarker.
A study published in Annals of Internal Medicine found that incorporating social and genetic factors into clinical risk calculators for coronary heart disease (CHD) improves prediction accuracy. The researchers developed a polygenic risk score (PRS) and polysocial score (PSS), which included social determinants of health and lifestyle-...
Researchers identified the critical role of TIMM50 protein in mitochondrial energy production and its link to a severe and rare neurological disease. The study's findings suggest potential targets for future drug treatments and advance research on protein import into mitochondria in brain cells.
A new study suggests that using AI-ECG tools to screen patients for low ejection fraction is cost-effective in the long term, especially in outpatient settings. The study found a cost-effectiveness ratio of $1,651 per quality-adjusted life year, indicating that the program can reduce costs over time.
A recent study found that excessive sitting significantly harms young adults, increasing the risk of heart disease and obesity. Reducing sitting time improves health outcomes, while doubling recommended exercise hours is more effective at lowering health risks.
The American Heart Association has launched a new three-year initiative to standardize HCM systems of care and support better management of the disease. The initiative aims to overcome gaps in care for hypertrophic cardiomyopathy, leading to delayed treatment, increased risk of complications, and preventable death.
Researchers at Karolinska Institutet and Columbia University identified a mini-brain within the heart with its own nervous system that controls the heartbeat. This discovery challenges current views on how the heartbeat is controlled and may lead to new insights into heart diseases and treatments.
A new study found that gene therapy delandistrogene moxeparvovec significantly extended the median survival of Duchenne muscular dystrophy (DMD) rats to >25 months. Additionally, the treatment elicited statistically significant improvements in cardiac parameters and mobility.
The study analyzed DNA from over 100,000 participants and found that nearly 2,000 carried at least one genetic variant linked to these diseases. The findings have led to life-changing discoveries and new insights into personalized medicine.
A study by St. Jude Children's Research Hospital has identified a serum protein panel test that accurately predicts cardiomyopathy risk in childhood cancer survivors. The test, using a panel of 27 proteins, was tested on 46 survivors and correctly predicted risk in 38 cases.
Researchers found that certain cancer treatments, such as immune checkpoint inhibitors, can trigger damaging levels of inflammation in the heart and increase risk of heart disease. This is because these treatments interfere with immune regulation in the heart's largest blood vessels.
A higher ratio of plant-based protein to animal-based protein may significantly lower the risk of cardiovascular disease and coronary heart disease. Consuming more plant protein overall, combined with a higher plant-to-animal protein ratio, provides the most heart health benefits.
A new review reveals how sleep disturbances exacerbate dementia symptoms, impacting overall health and caregiver well-being. The study emphasizes the need for holistic approaches to address coexisting conditions like cardiovascular disease and diabetes.
Ken Perry, a UTA senior, has been recognized for his research on the connection between high-fat meals and cardiovascular health. He won two awards from the American Physiological Society for his work analyzing data collected from previous studies, which showed a correlation between high-fat consumption and changes in brain blood flow.
A study of 49 million patients in England found that routine screening for cardiometabolic conditions like obesity and high blood pressure dropped sharply during the pandemic. Blood pressure measurements remained lower than pre-pandemic levels as of March 2024, particularly among lower socioeconomic groups.
A new study led by Weill Cornell Medicine found that tirzepatide reduced the risk of diabetes in obese and prediabetic patients by more than 90% after 176 weeks. The treatment also showed significant weight loss and improved blood sugar control.
Researchers found lower pulmonary gas exchange may be associated with impaired cognitive function in patients with long COVID. The study also showed a potential treatment strategy using methods that target improved gas exchange, suggesting a causative relationship between cognitive dysfunction and lung dysfunction.
Knowing family health history is crucial for reducing heart attack and stroke risk. Experts recommend following Life's Essential 8 - five health behaviors and three health factors to lower genetic risks.
The Heart Institute is celebrated for delivering unparalleled treatment and support to children with heart conditions. It has consistently provided high-quality cardiac care and specialized disease management for all forms of cardiomyopathy.
A new study by Intermountain Health found that coronary artery calcium scores are highly effective in identifying those at risk for future heart attacks and death, with similar predictive power in women as in men. The study revealed that individuals with a CAC score of zero were three times less likely to die from any cause.
Proactive screening of diabetic patients with coronary heart disease does not improve long-term survival rates or lower future cardiac events, according to a new study. The study found that focusing on proven interventions like medication management and lifestyle changes can help patients with diabetes lead healthier lives.
Research reviews suggest that exercise benefits outlast cardiovascular risks, even in those with heart conditions. Benefits outweigh risks due to medical screening, AEDs, CPR, and legislation. Studies found death rates increased starting from age 35, peaking in males over 45.
Researchers used Intermountain Risk Score to predict major cardiac events in patients being evaluated for kidney transplant, with a five-year follow-up period showing 171 patients experiencing cardiac events. The study's findings suggest the potential use of calculating such a score in people undergoing kidney transplant evaluation.
The Center for Translational Exposomics Research (CTER) at USC aims to accelerate environmental health research and find practical solutions. CTER investigates how different exposures impact health across populations using population studies, lab experiments, and community engagement.
Researchers evaluated coronary heart disease polygenic risk scores to determine their performance and agreement at the population level. They found that while scores performed similarly, they generated highly variable individual-level risk estimates, highlighting the need for refined statistical methods.
A new study by Intermountain Health found that air pollution primarily increases inflammation in patients with heart disease, particularly those with heart failure. Elevated inflammatory markers were observed in these patients during periods of poor air quality, suggesting they are more susceptible to the impacts of air pollution.
A diet rich in soybean protein β-conglycinin has been shown to increase short-chain fatty acid production, which plays a role in protecting the heart. Analysis of gut bacteria identified an increase in specific SCFA-producing bacteria, further supporting the potential benefits of soy on heart health.
According to the American Heart Association's Life's Essential 8, primary care clinicians can help patients reduce their risk of heart disease by addressing modifiable risk factors through lifestyle changes and treatment. Despite challenges, research shows that primary care professionals with a higher ratio have lower total costs of ca...
Singer Amy Grant's personal testimonial highlights the urgent need for support to save women's lives by funding research into better diagnosing, treating, and preventing cardiovascular disease. The American Heart Association aims to address awareness gaps and bridge clinical care gaps in women's heart health.
Researchers used machine learning to analyze data from 50 CF-LVAD patients and identified six prognostic factors that predicted post-implantation stroke. Lower levels of OxPhos proteins were associated with an increased risk of new strokes after implantation.