The COMBINE project focuses on the critical virus-cell binding step, aiming to identify key factors and potential therapeutic targets involved early in viral infections. The team will use a combination of pioneering approaches to develop novel inhibitors and vaccine candidates.
A breakthrough study reveals a critical pathway linking synaptic activity to gene expression changes necessary for learning and memory. Researchers identified the activation of receptors and ion channels generating calcium signals that rapidly communicate from synapses to the nucleus.
New research from PSU identifies lower streamflows as a contributing factor, while warmer temperatures led to significant increases in lake evaporation. The study suggests continued warming will exacerbate water loss, posing health risks and economic concerns for the region.
Anil Jain and Michael I. Jordan received the BBVA Foundation Award in Information and Communication Technologies for their pioneering work on machine learning, enabling transformative technologies like biometrics and artificial intelligence. Their research has unlocked applications of far-reaching impact on society.
A simulation study clarifies the physical mechanism of coupled plasma fluctuations, which can lead to significant losses of energetic particles in fusion research. The study reveals that the two fluctuations occur in a coupled manner via deformation of the energetic particle distribution function.
A recent study found that extreme climate events in fall 2022 pushed thousands of lakes in West Greenland across a tipping point, leading to changes in water quality, chemical properties, and biodiversity. The lakes, which previously provided drinking water and sequestered carbon, now emit more carbon dioxide.
Cancer vaccines hold transformative potential, leveraging neoantigens to activate the immune system against tumors. UK researchers are positioning themselves for a strategic shift in cancer vaccine trials, recognizing opportunities for improvement.
This study investigates the effects of Lianhua Qingke on endothelial protection in ALI/ARDS and finds that electromagnetic navigation bronchoscopy-guided microwave ablation is safe and effective in treating patients with multiple bilateral ground-glass opacities. The combination of ENB-guided MWA and VATS provides a potential for treat...
A new interposer design uses optical connections to transfer data between chips, enabling high-performance computing and addressing the 'memory wall' limit on AI growth. The technology allows for faster communication, reconfigurable pathways, and real-time network control.
A team of researchers from the University of Ottawa has developed innovative methods to enhance frequency conversion of terahertz (THz) waves in graphene-based structures, unlocking new potential for faster, more efficient technologies in wireless communication and signal processing. These advancements hold great promise for wireless c...
Singapore has joined the Global Network of Optical Magnetometers (GNOME) to search for signals of dark matter and exotic astrophysical fields. The Singapore station, hosted at A*STAR, will use advanced quantum sensors and machine learning algorithms to analyze magnetic field signals and potentially uncover dark matter's presence.
Researchers demonstrate the effectiveness of Ziapin2 in restoring ON, OFF, and ON-OFF responses induced by light stimuli in retinas with retinitis pigmentosa. The molecule restores light-induced behavior and visual acuteness for up to two weeks without toxic or inflammatory effects.
A pooled data analysis of 47,000 cancer patients found that high muscular strength and cardiorespiratory fitness were associated with a 31-46% lower risk of death from any cause. Tailored exercise programs may help increase survival rates in these patients.
Scientists from the University of Twente and INRAE discovered that releasing small particles of salt into a tank of water creates a circular pattern due to gravity-induced wake drag. The experiment reveals that the optimal amount of water and particle size affect the shape and size of the salt ring.
Ten life scientists have been awarded EMBO Installation Grants to establish laboratories in Croatia, Czechia, Estonia, Greece, Poland and Portugal. The grants support research projects on various topics including protein quality control and myeloid cell heterogeneity.
This study investigated the feasibility of electroacupuncture-assisted ribavirin dosing in patients with long COVID, using Voll's electropuncture diagnostics. The results demonstrated that EAV can identify meridians with decreased electrodermal activity at acupuncture points, followed by medicament testing to measure daily doses.
Researchers developed a sodium-doped amorphous silicon-boron-nitride catalyst that enhances reactivity and stability under harsh conditions. The material enables reversible hydrogen adsorption and desorption, making it a promising catalyst for sustainable industrial reactions.
A 2022 survey of Palestinians and Israelis identified 55 mutually preferable peace agreements to the status quo, highlighting areas of potential agreement. Women and older respondents showed a greater willingness to compromise than men and younger respondents, emphasizing the need for an immediate cessation of hostilities.
A lone spotted hyena was found in South Eastern Egypt, marking the first recorded instance of the species in this region for thousands of years. The individual was tracked and killed after killing two goats, providing evidence of how regional climate change can affect animal migration patterns.
The book, written by University of Illinois professor Lisa J. Lucero, explores the environmentally sustainable practices of the ancient Maya civilization, which has allowed them to persist for millennia despite dramatic changes. The author argues that adopting these techniques can help present-day societies overcome their own unsustain...
CISPA has signed the Africa Charter, a joint endeavour of major higher education bodies, to address structural disadvantages faced by scientists and research institutions in Africa. The charter outlines 10 principles for structuring research collaborations to overcome existing power imbalances.
The University of Texas at Arlington's College of Education and CONHI online master's programs have ranked among the top 60 in the nation. UTA's online programs offer flexible options empowering students to balance their studies with work, family and other commitments.
The open-access journal Plant Hormones focuses on fundamental research and reviews in plant hormone biosynthesis, signal transduction, and roles in growth and development. It aims to provide a platform for worldwide academic exchange and knowledge dissemination in the field of botany.
A study of 242 couples undergoing assisted reproductive treatment found that men experienced higher levels of work-family conflict, while women were more affected by stress. The researchers used online questionnaires to assess the couples' emotional well-being and job performance.
Researchers developed biodegradable paper-based temperature and humidity sensors that detect changes in relative humidity levels from 20% to 90% and temperature variations from 25°C to 50°C. These sensors are affordable, reusable, and environmentally friendly, offering a potential solution for precise monitoring of plant growth.
The UCF-led PARTNERS consortium aims to train a new generation of nuclear engineers and scientists, providing a talent pipeline for the NNSA. The $5 million grant will support students from underrepresented communities, providing research opportunities and internships at national labs.
A new deep learning model has been developed to detect and segment lung tumors on CT scans with high accuracy. The model achieved 92% sensitivity and 82% specificity in detecting lung tumors, outperforming physician-delineated volumes in some cases. However, further research is needed to improve the model's performance for larger tumors.
The Human Pangenome Reference Sequencing Project aims to accurately reflect human genetic diversity worldwide. With $14 million in NIH funding, the project will add genomes from an additional 200 individuals to its existing dataset of 550 diverse backgrounds.
Astronomers have traced a fast radio burst to an ancient, dead, elliptical galaxy, shattering assumptions that these events solely emanate from young star-forming regions. The discovery hints at the possibility of diverse origins for FRBs.
Dog owners cite emotional, physical, and social benefits of dog ownership, but also costly responsibilities. While daily life benefits include improved exercise and stability, the biggest cost is often cited as veterinary expenses.
A new longitudinal study has provided unprecedented insights into human papillomavirus (HPV) infection dynamics. The study found that non-persistent infections exhibit a plateau in viral load before rapidly declining, while chronic infections show a strong correlation between immune cells and virus production. This research could infor...
The study found that transitioning to healthy diets can minimize trade-offs and improve nutrition, health, the environment, and livelihoods in China. By adopting a holistic approach to food system transformation, policymakers can address social and environmental challenges while steering towards SDG targets.
Researchers tracked spur-winged lapwings in urban and rural areas, finding that city-dwellers are more mobile, especially during nesting season. The study also reveals seasonal differences in exploration patterns between males and females, highlighting the complex impact of human presence on bird behavior.
George Mason University researchers aim to build a framework for coordinated long-horizon tactical behaviors in multi-robot convoys through uncertain terrain. The project received $1,670,000 from the Army Research Laboratory and focuses on adapting, coordinating, and responding to unforeseen changes.
Researchers at TU Wien discovered a new energy band that remains connected by an 'umbilical cord' when one allowed energy range splits into two separate bands. This phenomenon is bound to occur in materials with large electron interaction, opening up a new perspective on technologically highly interesting classes of materials.
A systematic review and meta-analysis found that physical activity promotion interventions have minimal overall effectiveness. However, the
Researchers at The University of Hong Kong have discovered that the PICH protein plays a vital role in preventing genetic errors during cell division, which can lead to diseases such as cancer. Without PICH, cells experience severe DNA damage and accumulate genetic errors.
Kevin Bauer's new professorship at Goethe University Frankfurt aims to understand human-machine interaction and promote responsible AI research. His research focuses on the psychological and organizational factors determining the efficiency and quality of collaboration between humans and machines.
This study found a U-shaped association between waist circumference and all-cause mortality in women, and a J-shaped trend in men. The optimal waist sizes for minimizing mortality risk were 107 cm for women and 89 cm for men.
A recent study published in Nature Medicine analyzed over 2 million veterans taking GLP-1RA medications, finding benefits to cognitive and behavioral health while revealing increased risks for pancreatitis and kidney conditions. The study also showed decreased risks of seizures, addiction, suicidal ideation, and neurocognitive disorders.
Researchers studied the prognostic power of micropapillary patterns in PDAC, finding that even small percentages serve as independent prognostic factors for decreased survival. The study suggests incorporating micropapillary pattern percentage into pathology reports could enhance patient management strategies.
Scientists at IBEC create a system to control formation of intestinal crypts and villi using protein printing technique, enabling controlled analysis of gut biology. The method allows for detailed study of cell regeneration and diseases such as cancer and inflammatory diseases.
Jeffrey Given received the 2025 Frank Press Public Service Award from the Seismological Society of America (SSA) for his work in developing seismic monitoring tools and supporting the Comprehensive Test Ban Treaty Organization. His expertise spanned fundamental seismology to software development and data management.
A brain-computer interface has enabled a person with tetraplegia to control a virtual quadcopter by thinking about moving their unresponsive fingers. This technology provides unprecedented control, allowing the user to maneuver through a virtual obstacle course and potentially enabling remote work and social interactions.
Empa researchers suggest that building materials like concrete can absorb enormous quantities of carbon, offering a viable solution for reducing CO₂ levels. The concept of 'Mining the Atmosphere' aims to create a new global economic model using CO₂ as a raw material, with concrete accounting for a significant share of carbon storage.
Researchers identified 18 Japanese-specific genetic polymorphisms linked to allergic sensitization, as well as shared variants across both Japanese and European populations. The study highlights a major advancement in understanding the molecular mechanisms underlying allergic diseases.
Researchers developed a method to extract CO2 from flue gases with as little as 5% concentration using a superactive nickel-copper catalyst. The process involves adjusting electrical potentials and electrolyte, allowing access to previously unusable CO2 sources.
Researchers at Uppsala University found that people with psoriasis have invisible inflammation in their small intestine, which can lead to gastrointestinal problems and an increased risk of developing Crohn's disease. Half of the study participants had a leaky gut, allowing bacteria and harmful substances to leak through the intestinal...
Researchers analyzed data from a nationwide survey to understand the relationship between COVID-19 infection experiences and fear levels. The study found that mild infection experiences alleviated fear, while severe symptoms worsened it, and that fear decreased over time.
A study published in European Heart Journal found that face-to-face supervised exercise programs offer the greatest benefits for patients' mental health and quality of life. Home-based programs showed more modest results, highlighting the importance of professional supervision.
Mori received the award at the 2025 SSA Annual Meeting for his efforts in promoting SSA's international outreach, including a successful joint meeting with LACSC. He also supported the SSA Kanamori Fund to mentor and network early-career seismologists.
Scientists have successfully created nanoislands on silicon that can be controlled by an external electric field. These nanoislands exhibit swirling polar textures with promise for future applications in ultra-high-density data storage and energy-efficient transistors.
The book presents a comprehensive overview of the negative impacts of Prosopis invasions, including changes to land structure and groundwater depletion. Experts warn that if left uncontrolled, the invasion could spread to cover three-quarters of Kenya and cost USD 375 million annually.
Two new studies found that those who turned 65 after the ACA took effect had lower out-of-pocket health costs and fewer hospitalizations. However, dual-eligible individuals over 65 saw negative impacts from Medicaid 'unwinding,' with 12% losing coverage and many going without needed care due to cost.
A study by researchers at Helmholtz Munich has discovered that ancient viral DNA elements are re-expressed in mammalian embryos, playing a crucial role in early development. The activation of these elements is conserved across species and provides opportunities for manipulating thousands of genes simultaneously.
Researchers at HKUST have developed a world's smallest multifunctional biomedical robot, capable of imaging, high-precision motion, and multifunctional operations. The robot offers competitive imaging performance and extends obstacle detection distance up to ~9.4 mm.
A new study from Trinity College Dublin reveals that regular dog walking is associated with improved mobility, reduced fear of falling, and a lower likelihood of unexplained falls. The study, based on TILDA data, highlights the potential benefits of this simple activity for older adults.
The KAIST team developed a next-generation neuromorphic semiconductor-based integrated system that can learn and correct errors on its own. This technology will revolutionize AI use in everyday devices, making them faster, more private and energy-efficient.
A research team at DGIST developed innovative artificial muscle fibers that can produce and store energy, mimicking real muscles. The fibers, made from eco-friendly poly(lactic acid) and bio-based thermoplastic polyurethane, demonstrated exceptional durability and performance, with applications in advanced textiles, medical robotics, a...
A research team developed semiconductor fibers that emulate the five human senses, measuring changes in light, chemicals, pressure, pH, and mechanical strain. The fibers' unique structure allows precise control of their three-dimensional spiral shape, enabling them to detect a variety of environmental information.