Children's Hospital Colorado has launched a Sublingual Immunotherapy Program to treat children with 10 common food allergies, including milk, egg, peanut, and sesame. The program involves daily liquid drops under the tongue and may gradually build tolerance and provide greater protection against accidental exposure.
New national standards recommend earlier screening and lifelong monitoring for development and cognition in individuals with SCD, aiming to reduce variability in care. The guidance, developed in collaboration with Children's Colorado, provides a tiered approach to care, including surveillance and evaluation.
Children's Hospital Colorado has pioneered a groundbreaking approach to treating cystic fibrosis before birth, resulting in reduced NICU stays and improved pancreatic function. The pioneering care model uses ETI therapy to improve lung health and offers seamless continuation of treatment after birth through breast milk.
The Colorado Asthma-Friendly Schools initiative recognizes 221 schools for their comprehensive asthma management and student health efforts. Over 120,000 students have benefited from the implementation of evidence-based asthma management practices at school.
Researchers have identified five classifications of youth who have died by suicide, highlighting the importance of earlier detection and interventions. These classifications will improve primary care providers' understanding of specific risk factors and warning signs, enabling targeted prevention efforts.
Gracie Greenlaw, an 11-year-old patient with hypoplastic left heart syndrome, undergoes the world's first pediatric heart and liver dual organ transplant at Children's Hospital Colorado. The groundbreaking procedure, performed by Dr. Megan Adams' team, aims to improve her quality of life by addressing long-term complications from her h...
A multi-year clinical research study in US children documents the rebound of endemic respiratory viruses after the COVID-19 pandemic. The study shows that non-pharmaceutical interventions decreased circulation rates of common respiratory pathogens in children, enabling more accurate predictions for future outbreaks.
The hospital's new lab uses dynamic genomic technology to provide rapid results, integrate with electronic health records, and enable seamless at-home DNA collection. This enables doctors to explore patients' DNA, identify disease-causing mutations, and tailor treatment plans.
The new therapy significantly improves three-year disease-free survival for children with B-ALL, with 96% being disease-free for at least three years. Blinatumomab is now being used in most patients due to its practice-changing breakthrough, offering improved quality of life and reduced side effects.
The Heart Institute is celebrated for delivering unparalleled treatment and support to children with heart conditions. It has consistently provided high-quality cardiac care and specialized disease management for all forms of cardiomyopathy.
The study, conducted by Children's Hospital Colorado, found improvements in symptoms and quality of life for children diagnosed with celiac disease after participating in a mass screening program. Mass screening for pediatric celiac disease may become more common in the US, following similar conclusions drawn from European studies.
Children's Hospital Colorado is one of nine core sites nationally in the Pediatric Heart Network, a collective working to improve outcomes and quality of life for children with heart disease. The hospital's Heart Institute will conduct multisite research projects over the next seven years.
A new study published in The Journal of Pediatrics highlights the importance of timely newborn screenings in early care for cystic fibrosis. Late diagnosis can negatively affect short- and long-term growth and health outcomes in infants with cystic fibrosis, according to the research.
A new study from the National Institutes of Health RECOVER initiative found that post-acute COVID-19 in children is less common than in adults, but more frequent than hospitalization rates for acute COVID-19. Children with medical complexity and those younger than five years old are at higher risk of long COVID-19.
A study by Children's Hospital Colorado reveals a 77% surge in newly diagnosed youth-onset type 2 diabetes cases during the COVID-19 pandemic. The increasing prevalence of obesity and unhealthy habits since the pandemic's onset are thought to contribute to this rise.
Researchers are monitoring children for exposure to and responses to emerging pathogens, aiming to develop diagnostic, therapeutic and preventive tools for future pandemics. The study will inform the development of tests, treatments and vaccines that may be used in future pandemics.
A Children's Hospital Colorado study explores a neuromuscular training intervention to reduce injury risk in athletes returning from sports-related concussions. The research found that athletes who completed the 8-week training program had a significantly lower risk of time-loss injuries compared to those who did not participate.
The Sanford Children's Genomic Medicine Consortium has initiated a whole genome sequencing research project to investigate undiagnosed illnesses in children with suspected inborn errors of immunity. The study aims to sequence the genomes of up to 25 patient genomes and learn information that can benefit patients and others.
A recent study found that pediatric patients with Multisystem Inflammatory Syndrome (MIS-C) who received initial IVIG plus Infliximab had improved cardiac outcomes, reduced need for additional therapies, and faster resolution of inflammation. The updated care pathway recommends this intensified therapy for all MIS-C patients.
Children's Hospital Colorado is part of a national clinical research network studying pediatric asthma. The hospital will conduct a seven-year study on early-life determinants of chronic asthma to potentially reduce exacerbations and prevent development.
A new study by Children's Hospital Colorado found that lumacaftor/ivacaftor is safe and well-tolerated in children aged 2-5 with cystic fibrosis for up to 120 weeks. The treatment has also been shown to improve pancreatic function, reduce pulmonary exacerbations, and increase lung clearance.
Children's Hospital Colorado and STAQ Pharma developed pre-filled sterile injectables for pediatric patients, addressing drug shortages and medical waste. The partnership optimizes patient care by providing individualized medication concentrations and doses.
Researchers at Children's Hospital Colorado found that tetrahydrocannabinol (THC), the psychoactive component of marijuana, persists in breast milk for up to six weeks. The study supports recommendations to abstain from marijuana use during pregnancy and breastfeeding.
A new study published in Pediatrics found that younger and older adolescents have similar weight loss and improvement in quality of life after bariatric surgery. The study's results suggest that age should not be a barrier to bariatric surgery for adolescents with severe obesity when medically indicated.
A retrospective analysis of cesarean deliveries found using a wound infusion pump with enhanced recovery efforts reduced opioid use by more than 80%. A third of patients never took narcotic pain pills after the procedure.
A recent study published in Surgery for Obesity and Related Diseases found that bariatric surgery significantly reduced the long-term risk of cardiovascular disease in teenagers with type 2 diabetes. The study compared two cohorts of adolescents with type 2 diabetes over a five-year period, with results showing that treatment with bari...
Researchers at Children's Hospital Colorado have characterized the development of Natural Killer cells and innate lymphoid cells, crucial components in human health and disease. The findings pave the way for tailored therapies for children and adults undergoing cancer treatments.
Researchers at Children's Hospital Colorado found that 80-90% of adolescents experience remission of obesity-related complications after bariatric surgery. The study suggests that patients' health improves regardless of whether they sustain high levels of weight loss long-term.
According to a recently published commentary article, increased rates of dog bites in children have been observed during the COVID-19 pandemic. The authors attribute these increases to heightened stress for dogs and decreased adult supervision around dogs and children.
Recent studies highlight the benefits of bariatric surgery in adolescents, showing significant improvements in musculoskeletal pain, physical function, and quality of life after three years. Additionally, researchers found that patients may be at risk for iron and vitamin B12 deficiencies years after surgery.
A new study published in Diabetes Care found that bariatric surgery significantly decreased the rate of diabetic kidney disease among severely obese teens with type 2 diabetes, compared to medical treatment alone. The five-year study also showed improvements in hyperfiltration, urinary albumin excretion, and blood pressure.
A recent study found that telehealth effectively diagnosed and managed fetal congenital heart disease (CHD) in rural patients, achieving significant cost savings while maintaining high patient satisfaction. The study used real-time video consultation between medical experts and pediatric cardiologists, resulting in improved diagnostic ...
A new research network, CYSHCNet, aims to improve healthcare systems for children and youth with special needs. Led by Colorado and Boston hospitals, the network will coordinate national research activities to strengthen evidence-based care.
Researchers at Children's Hospital Colorado found that shorter sleep duration, later weekday bedtimes, and poor circadian timing were linked to reduced insulin sensitivity in adolescents with overweight or obesity. The study suggests potential benefits of improving sleep health through interventions like delayed school start times.
Researchers have identified a heterogeneous pattern on liver ultrasounds as a predictor of advanced liver disease in cystic fibrosis patients. Children aged 10 years old are at the average age of diagnosis, and 25% develop advanced liver disease within four years.
A multi-center study of adolescents reveals that bariatric surgeries like gastric bypass and sleeve gastrectomy lead to substantial weight loss, while adjustable banding is less effective. The study, which included 544 teens, found comparable weight loss outcomes for gastric bypass and sleeve procedures.
Dr. Peña has made significant contributions to pediatric surgery, particularly in treating anorectal malformations and other congenital anomalies of the pelvis. His work introduced the posterior sagittal anorectoplasty (PSARP) procedure, widely adopted by top surgeons worldwide.
Researchers found that an antioxidant-enriched multivitamin may decrease respiratory illnesses in people with CF by prolonging the time between illnesses and reducing inflammation. The study, led by Children's Hospital Colorado and the University of Colorado School of Medicine, involved 73 patients with pancreatic-insufficient CF.
A recent study published in JAMA Pediatrics found that bariatric surgery significantly improved health outcomes for adolescents with severe obesity and type 2 diabetes. The research, led by Children's Hospital Colorado experts, compared the effectiveness of surgical intervention to medical therapies in treating these conditions.
A multi-institutional study found that mandatory flu vaccines for healthcare workers increased vaccination rates by up to 30% and reduced absenteeism by about 6%. Vaccinated healthcare workers had a 30% lower rate of absenteeism compared to non-vaccinated colleagues.
Researchers led by Kevin Messacar have found that Enterovirus D68 (EV-D68) is a likely cause of Acute Flaccid Myelitis (AFM), a rare illness affecting children. The study advances prevention and treatment efforts, with improved awareness, surveillance, and investigations underway.
Researchers at Children's Hospital Colorado performed the world's first EXIT to ventricular pacing, stabilizing a preterm fetus's heart rate and ensuring a healthy delivery. The procedure gave the fetus time to recover before cutting the umbilical cord.
Recent research by Children's Hospital Colorado found that loss of control eating impacts bariatric surgery success rates in adolescents. The study, published in Pediatrics, revealed that patients who engaged in loss of control eating after surgery experienced poorer weight loss outcomes.
Researchers at Children's Hospital Colorado found that at-home use of Doppler fetal heart rate monitors can detect potentially fatal heart arrhythmias in fetuses, reducing the risk of death or complications. The study uses commercially available Dopplers for medical indications and has shown promising results.
Researchers have developed a minimally-invasive bioengineered material called RTG to cover neural tube defects in utero, offering an earlier gestational age approach to spina bifida repair. The study demonstrates the feasibility and potential of this alternative treatment method.
The hospital will use the funding to further engage stakeholders and conduct patient-centered comparative effectiveness research. The long-term goal is to design culturally-tailored interventions that will advance the health of Hispanic children.
The 'handshake stewardship' program, led by Sarah Parker, MD, reduced antibacterial use by 10.3%, antifungal use by 12.1%, and overall antimicrobial use by 10.9%. The program's success is attributed to daily pharmacist-physician reviews and in-person advice on antibiotic usage.
A new online genetic study called SPARK is enrolling thousands of people with autism and their families to identify the hundreds of autism genes at play. The study seeks to connect these individuals and families to research opportunities that advance the understanding of autism.
Research from Children's Hospital Colorado found that wearing a helmet while skiing or snowboarding lowers the risk of sustaining severe head injuries. The study also discovered that nearly twice as many local Colorado children wear helmets compared to out-of-state visitors.
A groundbreaking study released in The Lancet shows that a single injectable dose of inactivated polio vaccine (IPV) along with bivalent oral polio vaccine can protect up to 90% of children from polio. The research demonstrates faster and stronger protection compared to using the oral vaccine alone.