Research on the causes and treatment of heart disease. Covers light exposure and heart health, sex differences, heart-in-a-dish models, and cardiac risk.
A new study from Uppsala University investigates how sleep deprivation affects biomarkers associated with cardiovascular disease. Researchers found that chronic lack of sleep increases the risk of heart problems by promoting inflammatory proteins.
Viet Le, a clinician and researcher, will serve as the next editor of the American College of Cardiology's CardioSmart program. The program aims to personalize care and foster partnership between patients and clinicians through trusted resources and tools.
A study published in the Journal of Internal Medicine found that individuals with Down syndrome have a higher risk of age-related cardiovascular diseases, particularly ischemic stroke and hemorrhagic stroke. The researchers also noted an increased risk of heart attack in young people with Down syndrome.
A study of 273,770 individuals with cardiovascular disease found that increasing lipoprotein(a) levels significantly increases the risk of subsequent cardiovascular events. Treatment with high-impact LDL-C lowering therapies may help reduce this risk.
Researchers at University of East Anglia developed 4D flow MRI scan to diagnose aortic stenosis more accurately and reliably than current ultrasound techniques. The technology offers more accurate measurements of blood flow through heart valves, leading to better prediction of when patients need surgery.
Researchers found persistent inflammation in heart and lungs of patients with long COVID, even after standard tests return normal results. This study uses advanced PET/MRI imaging to detect abnormal patterns that could serve as early warning signs of future cardiac and pulmonary conditions.
Dr. Kenneth Rosenfield is a distinguished interventional cardiologist recognized for his seminal work in endovascular therapy and pioneering innovative techniques. He has made significant contributions to the field of vascular medicine, including the development of self-expanding stents and drug-coated balloons.
The SCAI/SCCT expert opinion document presents a comprehensive framework for using CCTA to guide PCI. It outlines current evidence and future opportunities, providing practical guidance on image acquisition, interpretation, and procedural strategy. The document aims to bridge the gap between imaging and intervention, emphasizing educat...
A new MRI technique measures a person's 'functional age' of their heart, revealing how unhealthy lifestyles add years to their heart's aging process. This method has the potential to transform heart disease diagnosis and offer a lifeline to millions by catching problems early.
A new analysis of population surveys estimates that exposure to di-2-ethylhexyl phthalate (DEHP) contributed to 356,238 global heart disease deaths in 2018, accounting for 13% of all global mortality. The study also found higher death risks in the Middle East, South Asia, East Asia, and Pacific regions.
The CHLA team has demonstrated the possibility of using genetically engineered pig hearts as a 'bridge' to heart transplant for critically ill babies. Eight baboons have survived with a pig heart, with one living for nearly 21 months.
A highly sensitive bone marrow test has shown to double survival rates for patients with AML mutations in NPM1 and FLT3 genes, allowing for early detection of potential relapse. This trial indicates that regular molecular testing can improve long-term survival rates by restarting treatment earlier.
Scientists developed an injectable therapy that protects the heart from damage after a heart attack by blocking the interaction between two proteins, Keap1 and Nrf2. The study showed decreased inflammation, cell death, and improved cardiac function in animal models.
Researchers developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack, showing effectiveness up to five weeks after injection.
A new AI algorithm, Viz HCM, can quickly and specifically identify high-risk heart patients with hypertrophic cardiomyopathy (HCM) and provide individualized risk assessments. The algorithm's findings can help doctors prioritize the highest-risk patients for earlier appointments and treatment.
Researchers identified a potential new treatment, lorundrostat, which reduced systolic blood pressure in individuals with uncontrolled or treatment-resistant hypertension. The study found a significant 15-point reduction in systolic blood pressure compared to placebo.
A new AI algorithm can automatically assess stent healing in OCT images, differentiating between healthy and unhealthy tissue with high accuracy. This technology has the potential to improve clinical decision-making and reduce healthcare costs by providing precise measurements and valuable insights for patient management.
Research found that bad habits like smoking, heavy drinking, and lack of exercise can lead to declines in health as young as 36, with effects more pronounced over the long-term. The study tracked hundreds of people for 30 years and found that three unhealthy behaviors were linked to poorer mental and physical health.
A pioneering Israeli study identifies TRIM63 as a significant genetic contributor to hypertrophic cardiomyopathy (HCM), which could transform genetic screening and treatment protocols. The findings provide compelling evidence for the gene’s role in both causing and increasing susceptibility to HCM.
Professor Sun has been recognized for her transformative advancements in devices used for disease diagnosis, communication, and military safety. Her multidisciplinary research has secured over $8 million in external funding from premier organizations.
A new AI algorithm has been calibrated to quickly identify patients with hypertrophic cardiomyopathy (HCM) and provide individualized risk assessments. The tool can help prioritize high-risk patients for earlier appointments and treatment, leading to better patient outcomes.
The American Heart Association funds research teams to investigate how risk factors for cardiovascular and kidney diseases impact women differently. The project aims to understand the biological significance of certain life cycles and societal factors on disease development.
A new analysis found that oral hormone therapy can lower levels of lipoprotein(a), a genetic risk factor associated with higher risk of heart attack and stroke. Hormone therapy also improved biomarkers of cardiovascular health, including cholesterol levels.
Researchers at Penn's School of Dental Medicine and Perelman School of Medicine found that ACE inhibitors can inhibit the activity of ACE2, a critical cardioprotective enzyme. This discovery has implications for human patients prescribed these medications, who may benefit from additional ACE2 treatment.
Researchers found that adults under 50 with migraine headaches and certain heart defects are at increased risk of stroke. The study highlights the importance of assessing both traditional and nontraditional risk factors in younger people to prevent strokes.
Researchers at UCL developed a new scoring system, CAR, to identify patients with narrowed carotid arteries who can be effectively treated with optimised medical therapy. The study found low rates of recurrent strokes and heart attacks among patients treated with medication alone.
Aging-associated mutations in the Dnmt3a gene boost mitochondria power in blood stem cells, leading to clonal hematopoiesis. New mitochondrial-targeting drugs show promise in treating age-related illnesses by selectively weakening mutated cells without impacting normal ones.
A new genomics tool, refget Sequence Collections, streamlines genomic research by standardizing reference sequences. This enables scientists to compare data more efficiently and accelerate medical breakthroughs.
Dr. Rhonda Winegar investigates the effectiveness of music therapy in supporting neurological care, including its ability to reduce anxiety and depression in Alzheimer's patients. Her research also highlights its potential to regulate heart rate and blood pressure, as well as improve motor function in individuals with Parkinson's disease.
The Mount Sinai Fuster Heart Hospital cardiology faculty practice has received the 2024 Human Experience Pinnacle of Excellence Award from Press Ganey, a leading patient experience organization. The hospital ranks among the top 5% of healthcare providers in delivering patient experience over three years.
A new study from Karolinska Institutet found that people with a certain heart valve abnormality are at increased risk of severe heart rhythm disorders even after successful valve surgery. The condition is more common in women and younger patients, and can lead to sudden cardiac arrest.
Adverse pregnancy outcomes like gestational diabetes and high blood pressure contribute significantly to cardiovascular disease risk factors in midlife. Prioritizing weight management among those considering pregnancy may promote both maternal and future cardiovascular health.
A new American Heart Association scientific statement emphasizes the importance of multidimensional sleep health in reducing cardiometabolic risks. The statement reviews evidence on the relationship between sleep and various health factors, including body fat, blood sugar, cholesterol, and blood pressure.
Stephan Windecker, a world-renowned cardiologist, will be honored with the TCT 2025 Career Achievement Award for his extraordinary contributions to interventional cardiology. His extensive research has shaped clinical practice worldwide and influenced the future of cardiovascular medicine.
A new study found that death rates from alcohol in England increased by a fifth in 2020, rising further between 2020 and 2022. The largest increases were among men, people from deprived areas, and those aged 50-69, mainly due to liver damage caused by alcohol.
The WNFC's player ambassadors will amplify public service announcements, social media content, and local community education events to raise awareness about cardiovascular disease and CPR education in women. The league has also implemented a requirement for all coaches to be certified in CPR, AED, and first aid.
A new study found that a 2018 US public housing smoking ban led to reduced hospitalizations for cardiovascular problems. The ban resulted in modest declines in heart attacks incidence rates and small differential declines in strokes among adults aged over 50.
Researchers at the University of Cambridge have developed a handheld device that can accurately record heart sounds without requiring precise placement on the chest. This innovative device, which uses six sensors to capture clearer heart sounds, has the potential to transform heart disease screening and diagnosis.
A study of nearly 30,000 adults found that heart failure is associated with a significant decrease in cognition at diagnosis and rapid decline over time. Adults with heart failure reach the threshold for meaningful decline in global cognition nearly six years earlier than those without it.
The device uses AI technology to detect potential heart problems and provides real-time health insights. It has multiple points touching the skin near the heart, allowing for more accurate tracking even during movement.
A new study suggests AI-driven smart devices can revolutionize healthcare by detecting cardiac issues early, triggering emergency responses. The Internet of Medical Things (IoMT) technology enables real-time patient monitoring and analysis, improving efficiency and reducing costs.
A new imaging technology has been developed that combines super-resolution imaging with artificial intelligence to reveal subcellular structures and dynamics in living cells. This breakthrough enables scientists to better understand the root causes of diseases, leading to improved treatments.
The American Heart Association invites communities nationwide to walk together on National Walking Day to break the cycle of sedentary behavior. Regular walking can improve both physical and mental well-being, even in small steps.
A new study found that compound heatwaves significantly increase cardiac mortality and are more impactful than traditional binary definitions of heatwaves.
A recent NIH-funded study found that rural adults experience higher rates of heart disease and its risk factors compared to urban counterparts. The study revealed that variables such as poverty, education, and access to healthcare do not explain these differences, with lifestyle risk factors like smoking also playing a lesser role.
Researchers from Emory University are using the International Space Station to study cardiac cells and accelerate the development of cell-based regenerative therapies. The team's findings have led to multiple peer-reviewed publications and could significantly advance methods to produce cardiac cells for heart disease treatment.
The American Heart Association has launched a new certification program for hospitals dedicated to optimizing heart failure treatment, reducing readmissions. The Heart Failure Center Certification aims to enhance patient outcomes and promote evidence-based treatments.
A meta-analysis found that people with moderate to severe systolic dysfunction had a smaller total brain volume than those with normal systolic function. Additionally, individuals with diastolic dysfunction problems also showed reduced brain volumes and hippocampus area damage.
Chronic kidney disease rates increased by 24% globally from 1990 to 2021, linked to higher cardiovascular disease risk. Collaborative care and screening for cardiovascular-kidney-metabolic syndrome can reduce mortality and improve patient lives.
Researchers at WashU have developed a method to manipulate the mechanical side of fibrosis, a complex condition that can lead to scarring and breathing difficulties. By controlling the direction of tension forces, they aim to prevent or treat fibrosis and develop personalized treatment plans for patients.
The UH Portage Medical Center's heart lab and prevention programs have shown a significant reduction in ischemic heart disease mortality, especially among older adults. The study found declines of 36% in the 65-74 age group and 28% in those over 85.
Researchers identified a Y chromosome-linked gene, UTY, as a key driver of valve calcification in males. In females, fibrotic tissue formation stiffens the valve, leading to different disease progression. The study highlights the importance of sex-based mechanisms in heart valve disease
A deep learning model analyzes breast arterial calcification and translates results into a cardiovascular risk score, helping identify patients at higher risk of heart disease. The tool is particularly useful for younger women, who can benefit from early interventions.
TCT 2025 will take place October 25-28, 2025, at the Moscone Center in San Francisco, California. The event will feature acute interventions, breakthrough technologies, and cutting-edge research driving the next era of cardiovascular care.
Scientists have developed a low-cost and easy-to-use diagnostic tool for assessing cardiovascular disease risk using molecular blood screening. The technology enables high-throughput analysis of key lipoprotein markers in under 15 minutes, providing clinicians with a rapid and reliable diagnostic tool.
Two new studies have found a substantial link between cannabis use and an increased risk of heart attack. The studies, one retrospective and one meta-analysis, pooled data from over 4.6 million people, showing that cannabis users under the age of 50 were six times more likely to suffer a heart attack than non-users.
Researchers at the University of Virginia Health System have developed a computational tool called LogiRx that can predict how drugs will affect biological processes in the body. The tool has demonstrated its potential by identifying a promising candidate to prevent heart failure, a leading cause of death worldwide.
This special issue explores AI's applications across various subspecialties, including coronary interventions, structural heart disease, and cardiovascular imaging. It highlights the importance of responsible AI integration and addressing bias in decision support systems.
The study found that tunneling nanotube-like structures connect cells in the heart, enabling long-distance intercellular communication essential for heart formation. Disruption of these structures resulted in impaired ventricular wall morphogenesis and defective myocardial growth.
The American College of Cardiology has issued a new clinical policy providing streamlined processes for the evaluation and management of cardiogenic shock. The guidelines emphasize early recognition, comprehensive assessment, and effective medical management to preserve organ performance and reduce mortality rates.