Researchers developed a technique to analyze DNA methylation marks, identifying changes in blood production that occur with age. By age 50, many blood stem cells begin to drop out and larger clones take over, leading to a decline in diversity and resilience.
Researchers use NASA's James Webb Space Telescope to investigate a protoplanetary disk around a young star in the Lobster Nebula. They found sufficient solid material to potentially form at least 10 rocky planets and detected various molecules that contribute to planetary atmospheres.
More than half of US workers report significant stress due to job insecurity, with 54% saying it impacts their work life. Government policy changes and economic concerns exacerbate workplace stress, affecting employees' mental health and overall well-being.
A 1,200-tonne boulder in Tonga is one of the largest known wave-transported rocks, providing new insights into past tsunamis. Numerical modelling suggests tsunami heights of 50m lasting 90 seconds dislodged the boulder from its cliff-edge origin.
Researchers developed a room-temperature THz detector that offers high sensitivity, fast response, and scalability for large-scale arrays. The use of a two-dimensional electron gas channel enables non-equilibrium carriers to travel faster and more efficiently, broadening the THz response range.
Researchers at Johns Hopkins University Applied Physics Laboratory have developed nano-engineered thermoelectric refrigeration technology with controlled hierarchically engineered superlattice structures (CHESS) that is twice as efficient as traditional bulk materials. The CHESS technology offers a scalable alternative to traditional c...
Researchers have developed a comprehensive system to identify the diversity of reef-building corals using environmental DNA (eDNA) metabarcoding. This new method successfully detects 83 of 85 genera of Scleractinia in Japan, providing a powerful tool for efficient monitoring and conservation of coral reefs.
The Global Virus Network strongly supports the World Health Organization's newly adopted Pandemic Preparedness Accord, which establishes a more coordinated and transparent global framework for pandemic prevention, preparedness, and response. The accord reaffirms priorities on sustained investment in global surveillance, rapid data shar...
A new study reveals that Aspergillus fumigatus infection can unbalance the lungs by creating a microaerophilic niche for bacteria like Ligilactobacillus murinus. This interaction may influence disease progression and enable new treatment approaches, highlighting the importance of understanding the gut-lung axis.
Researchers at Istanbul Galata University studied the history and architecture of Derinkuyu's ancient underground city to recreate its soundscape. The project aims to provide valuable information for scholars and inspire the design of future underground urban spaces.
A new study found that intensive blood pressure reduction had similar outcomes across educational attainment levels, but high-educated individuals experienced greater cardiovascular risk reductions. The research analyzed data from the SPRINT trial and suggested that unmeasured social factors may play a role in heart health disparities.
Scientists at Linköping University have made a significant breakthrough in creating controllable flat optics using nanostructures on a flat surface. By precisely controlling the distance between antennas, they achieved up to tenfold improvement in performance, opening up new avenues for applications such as video holograms and biomedic...
New research reveals that recreational cannabis legalization leads to significant reductions in prescription drug claims per enrollee, with annual savings of $34-$42 in small group insurance markets. However, the study found no similar effect in large group insurance markets.
Researchers successfully created over 1000 new biological tools, known as enhancer AAV vectors, that can target specific brain cell types. These tools offer unprecedented access to brain cells and hold promise for targeted gene therapies to correct genetic defects in specific cells contributing to disease.
Researchers discovered a novel mode of contact between somatic and germ cells in the ovaries of two arthropod species, challenging the general understanding of epithelial layer function. The basement membrane, typically a barrier, is penetrated by follicle cells to establish direct contact with oocytes.
A cohort study of over 11,000 children and adolescents found a significant association between increased social media use and greater depressive symptoms. Clinicians are advised to provide guidance on social media use for young adolescents and their parents.
The FAITAVI trial found that FFR-guided PCI reduced major adverse cardiac and cerebrovascular events at 12-month follow-up in patients with intermediate coronary artery disease undergoing TAVI. FFR-guided PCI was associated with lower rates of all-cause death and ischaemia-driven target vessel revascularisation.
Researchers from The University of Osaka observed a rare phenomenon where lightning discharges accelerated electrons to near light speed, producing a gamma-ray flash. This study contributes critical data to understanding the mechanism behind these intense radiation bursts and their potential role in shaping Earth's atmosphere.
A study from Imperial College London and Coventry University found that older adults with positive self-perceptions about ageing are less likely to experience physical problems after a fall. They were also more likely to physically recover in the months following a fall.
Scientists have found that oceanic anaerobic respiration produces sulfur species, forming pyrite or 'fool's gold', which helps buffer the alkalinity of water and prevent acidification. This process has a stabilizing effect on the ocean, playing a significant role in preserving its alkalinity for millions of years.
OneCareAI applies AI and supercomputing to detect early stroke risk from ECG data obtained with smartwatches, offering a non-invasive solution for personalized risk assessments. The technology has the potential to be extended to other cardiovascular diseases, opening opportunities for scalability.
Researchers from Kyushu University found that climate models significantly overestimate the fraction of ice in wintertime Arctic clouds, leading to skewed warming predictions. This error has significant implications for current and future global warming projections.
A new INFORMS Management Science study reveals AI-powered traffic cameras improve overall road safety by promoting safer driving behavior and reducing accidents. The study estimates that citywide deployment of AI-enabled cameras could prevent approximately 1,190 accidents annually.
Researchers at Thomas Jefferson University found that VDAC2, a mitochondrial protein, can make liver cancer cells more vulnerable to existing treatments targeting BAK-dependent cell death. The study suggests that combining pre-clinical drugs targeting BAK could shrink tumors in mice with high levels of VDAC2.
Researchers at Rice University have developed a novel personalized medicine approach for addressing movement impairments. The Neuromusculoskeletal Modeling (NMSM) Pipeline software allows clinicians to work in collaboration to construct personalized computer models of individual patients, leading to more effective orthopedic surgery, p...
Dr. Alana Welm has been appointed as the Chair of Oncological Sciences, leading efforts to advance research, education, and clinical impact. With a focus on innovation and collaboration, she aims to foster a culture of excellence and position the department for national distinction.
A Canadian Medical Association Journal study found that single-entry referral models and team-based care significantly reduced surgical wait times. The research analyzed data from 17,465 surgeries and recommended implementing these models to improve access to healthcare services.
A new study reveals that pregnant individuals and their infants in high-risk wildfire areas face significant barriers to accessing healthcare due to limited resources. The researchers found that communities at high risk of smoke exposure have substantial resource constraints, making it challenging for them to receive timely treatment.
A new study reveals that untreated wastewater released into the Chicago River during extreme rain events significantly alters the freshwater ecosystem. Zooplankton populations disappeared or increased dramatically, affecting the entire food web and potentially infusing harmful chemicals into the water.
Researchers linked comprehensive datasets with physical ocean processes to understand the exceptional marine biodiversity around the Cape Verde Archipelago. The study identified three key mechanisms driving nutrient transport and found that physical dynamics influence not only productivity but also the type of organisms present.
A new study found that adopting low-carbon lifestyles can reduce global carbon footprints by 10.4 gigatons of CO2 equivalent, equivalent to 40.1% of household consumption-based emissions in 116 countries analysed. Researchers identified 21 low-carbon actions that could achieve this reduction if adopted by the top 23.7% of global emitters.
Scientists at MIT have identified new potential targets for treating Alzheimer's disease, including a pathway involved in DNA damage repair. The study suggests that a combination of treatments targeting different cellular pathways may be more effective in blocking disease progression.
The $10 million facility will evaluate machinery powered by hydrogen, hydrocarbons and other flammable gases for efficiency, safety and reliability. SwRI aims to improve natural gas technology, reducing carbon emissions and increasing power supply sustainability.
The proposed framework addresses challenges in autonomous robotic surgery by integrating multiple soft tissue manipulation modes and adapting to dynamic environments. The ID-SAC algorithm outperforms traditional SAC algorithms, achieving faster task completion times and smoother trajectories.
Emerging research links microbial dysbiosis to aging, as dysbiosis accelerates DNA damage and telomere shortening. Therapeutic strategies targeting the microbiome may promote healthy longevity.
A study by University College London researchers found that depressive symptoms worsen long before pain begins in middle-aged and older adults. Early mental health interventions may help prevent or reduce later aches and pains.
Scientists at the University of Surrey have developed a breakthrough in eco-friendly batteries that store more energy and capture carbon dioxide. The new lithium-CO₂ 'breathing' batteries use a low-cost catalyst to overcome efficiency issues, potentially leading to widespread adoption and reducing emissions.
Researchers at La Jolla Institute for Immunology discovered that CD4+ T cells target Chikungunya virus, leading to chronic inflammation and joint pain. The study suggests that these monofunctional T cells may be the culprits behind arthritis-like symptoms in CHIKV patients.
Professor Lars Wallentin and Professor Stefan James will receive the award on behalf of a wider team of Swedish cardiovascular registry experts who have advanced cardiovascular medicine through SWEDEHEART and SCAAR registries. The award recognises their contributions to improving patient care in Sweden and globally.
A new analysis of over 18,000 cancer cases suggests that obese patients may fare better after immunotherapy treatment, with improved overall survival rates. The study's findings raise intriguing questions about the role of obesity in immunotherapy effectiveness and highlight the need for further research to understand this phenomenon.
A new framework for assessing traumatic brain injuries (TBI) will provide more accurate diagnoses and treatments, leading to better patient outcomes. The framework incorporates clinical symptoms, biomarkers, imaging scans, and modifiers to determine the severity of injury and predict recovery.
New research from the University of the Witwatersrand finds that puff adders can increase their food consumption by up to 12 times during rodent outbreaks, outperforming traditional mammalian predators. This natural solution could significantly reduce crop damage and support sustainable farming practices in Africa.
The study finds that selecting the least confident bidder as the auction winner enhances learning accuracy, leading to higher delivery rates and shorter times. The approach promotes smarter resource deployment by matching drones' capabilities to tasks.
A new study has found that combined oral contraceptives are associated with a threefold increase in the risk of cryptogenic ischaemic stroke (CIS) in young women. CIS accounts for up to 40% of all ischaemic strokes in young adults, and prior studies have linked hormonal contraception to vascular risk.
A study published in Land Economics found that farmers in rural areas of Pennsylvania are more likely to adopt best management practices for clean water conservation when provided with financial incentives. However, farms in urban areas are also adopting these practices voluntarily without incentives.
A new study reveals that synthetic opioid-involved fatal overdoses among youth aged 15-24 in the US were predominantly caused by fentanyl alone. The rates of overdose deaths involving only fentanyl increased significantly across age, sex, and race/ethnicity, with the highest rates found among males and young adults.
Research highlights potential link between microplastics in ultra-processed foods and brain health, with possible connections to depression and dementia. The studies propose a novel hypothesis connecting ultra-processed food consumption, microplastic exposure, and mental health outcomes.
A new study published in Radiology found that abbreviated breast MRI is an effective screening method for women with extremely dense breasts, detecting cancer while reducing scan times by up to 80%. The abbreviated protocol retains a high level of diagnostic accuracy comparable to the full protocol MRI.
A new study from Oxford University finds that people in poverty are more likely to feel lonely than those with higher incomes, despite similar socialization patterns. Strong social connections were shown to have the greatest symptom-reducing effects for those living in poverty.
A new study at the University of Turku identified conditions under which Bexmarilimab activates the immune system against cancer. The drug was shown to trigger B cell-mediated immune responses in healthy tissue adjacent to tumors. This could lead to more accurate patient selection and improved treatment outcomes.
Researchers have developed a new bluish-green emitting phosphor using silica nanoparticles, achieving a 48% increase in emission intensity compared to traditional methods. The phosphor exhibits significant thermal stability, making it suitable for high-power LEDs and paving the way for brighter, more energy-efficient LED lights.
Researchers at Penn State found that metformin increases fertile egg production, reduces body fat, and improves reproductive hormone levels in broiler breeder hens. The study suggests that metformin can extend the productive lifespan of these chickens, potentially improving animal welfare and efficiency in poultry farming.
A new study by the University of South Australia found that using AI alone in hiring decisions does not necessarily lead to more diverse and inclusive outcomes. The research highlights the importance of organizations having clear diversity guidelines, qualitative goals, and human oversight to support the use of AI tools effectively.
A new study from the University of Surrey finds that African tourism entrepreneurs employ proactive strategies to overcome challenges, including operational adjustments, resource management optimisations, and creative pricing tactics. This approach significantly enhances their resilience and wellbeing amid adversity.
The article proposes two AI-guided models to transform psychology education, focusing on knowledge acquisition and standard-setting. These models aim to cultivate adaptable problem-solvers, leveraging AI in educational reform.
Researchers found that consuming foods high in methyl adaptogens, such as green tea and berries, can reduce markers of epigenetic aging. The study, which involved middle-aged men, suggests that targeted food choices may help slow the aging process.
A new study found that pod-style electronic cigarette devices are more addictive than nicotine gum, indicating a high potential for abuse. The study used a sample of adult non-smokers and found that vaping devices decreased cravings and withdrawal, but increased satisfaction.
A patient with cutaneous squamous cell carcinoma was treated with WTX-124 and achieved complete remission after 12 weeks. The investigational drug is designed to stimulate antitumor immunity with reduced toxicity, offering new hope for patients with limited treatment options.
Patients with mitochondrial diseases face serious health issues, and a new study reveals that damaged mitochondria put the immune system on overdrive, leading to severe infections. The researchers identified specific molecules that could be targeted with new treatments to protect this vulnerable population.
A novel analysis suggests more than 3,500 animal species are at risk from climate change, with significant threats to invertebrates and marine life. The study highlights the need for a global database on mass mortality events due to climate change and integration of biodiversity and climate change policy planning.