Healthy kidneys despite hypertension
Researchers found that a mutated PDE3A gene prevents kidney damage despite severe hypertension. The study suggests that this mutation could be used therapeutically to prevent chronic kidney disease.
Articles tagged with Hypertension
Researchers found that a mutated PDE3A gene prevents kidney damage despite severe hypertension. The study suggests that this mutation could be used therapeutically to prevent chronic kidney disease.
A study by Japanese researchers identifies the involvement of angiotensin II-AT1 and prostaglandin E2-EP1 systems in high-salt-induced hypertension and emotional/cognitive impairment, offering potential therapeutic targets for dementia prevention.
A low-cost clip attachment uses a smartphone's camera and flash to monitor blood pressure, making it easy and affordable for resource-poor communities. The technology was tested on 24 volunteers and showed comparable results to traditional blood pressure cuffs.
Researchers investigate whether pregnant mothers' exposure to toxic metals affects kidney development in their babies, which may set the stage for chronic kidney disease. The team aims to identify key combinations of metal mixtures that could have detrimental effects on developing kidneys.
A new combination treatment for brain hemorrhage significantly improves survival rates and reduces disability. The INTERACT3 study shows a Care Bundle of readily available treatments can improve outcomes, particularly in low- and middle-income countries where most cases occur.
Women with short or long menstrual cycles are at increased risk of cardiovascular disease events such as heart attack or AFib. The study analyzed data from over 58,000 women and found that irregular menstrual cycle length was associated with higher risks of CVD, independent of other factors.
Primary care clinicians reported a range of experiences with telemedicine, from ease of adoption to challenges in conducting physical exams and diagnostic testing. The study also found that telemedicine had both positive and negative impacts on providers and patients, highlighting the need for clear regulations and adequate staffing pr...
A randomized trial found that very low carbohydrate diets led to greater improvements in systolic blood pressure, glycemic control, and weight compared to the DASH diet. The addition of extra support did not have a statistically significant effect on outcomes.
Researchers identified novel genetic associations between AD and modifiable risk factors, including high HDL cholesterol concentrations and systolic blood pressure. These findings may inspire new drug targets and improved prevention strategies for AD.
A study published by the European Respiratory Society found that around 20.2% of French adults are likely to have obstructive sleep apnoea (OSA), with only 3.5% being treated for the condition. OSA is more common in men, older adults, and those with cardiovascular disease.
Research highlights unique effects of Asian American subgroups on heart disease and Type 2 diabetes risk. Variations in cardiovascular risk among Asian Americans indicate the need for individual subgroup data to better understand health risks.
Research published in European Heart Journal – Digital Health found a 12% increased risk of high blood pressure among mobile phone users who spent 30 minutes or more per week on calls. This association held true even after adjusting for other risk factors, suggesting that the duration of phone conversations may be a crucial factor.
Researchers at West Virginia University found that bariatric surgery significantly reduces the risk of major cardiovascular events and death in patients with NAFLD. The study included 9,374 adult patients with NAFLD and obesity, who underwent either Roux-en-Y gastric bypass or sleeve gastrectomy.
More than half of stroke survivors develop cognitive impairment within a year, with 1 in 3 at risk for dementia. Early screening and comprehensive care are advised to support stroke survivors with cognitive impairment.
Strokes can be largely prevented through education and lifestyle changes, such as moving more, healthy eating, and managing blood pressure. The American Stroke Association is launching a digital tool to educate people on stroke warning signs and risk factors, particularly for diverse populations.
Researchers from Nemours Children's Health present findings on pediatric mental health, HPV vaccination strategies, primary hypertension in youth, and the effects of social media on pediatric care. The studies aim to improve child well-being and provide innovative approaches to addressing pressing topics.
High night-to-night variability in sleep apnea severity is associated with uncontrolled hypertension, increasing cardiovascular risk. The study found a 50-70% increased likelihood of cardiovascular events and mortality.
A new study published in the Journal of the American Heart Association found that U.S. adults who experienced workplace discrimination were more likely to develop high blood pressure. The research, which analyzed data from over 1,200 adults, suggests that work-related stress due to discrimination may be an emerging risk factor for card...
A new study published in JAMA Network Open found that intensive blood pressure treatment significantly reduces the risk of adverse cerebrovascular events such as stroke. Participants with hypertension who received intensive treatment showed reduced white matter lesions and improved blood flow, indicating better overall brain health.
A growing number of states have implemented policies to cover outpatient hemodialysis for undocumented immigrants with kidney failure. This expansion may be due to increased awareness of poor outcomes with emergency hemodialysis and advocacy efforts. The move towards covering dialysis in all 50 states is called for by experts, who also...
Individuals who experienced depression during pregnancy were more likely to be diagnosed with cardiovascular disease within two years after giving birth. The study found a significant higher risk of developing six major cardiovascular conditions, including heart failure and ischemic heart disease.
A €10M Horizon Europe grant will support the development of a clinical decision support tool using artificial intelligence to select the best treatment for each individual patient with high blood pressure. The project aims to improve patient care and reduce avoidable consequences such as heart attacks, strokes, and kidney disease.
A Mayo Clinic study found that people with severe obesity and a genetic pathway variant are at increased risk of developing hypertension. The research identified 168 carriers of the MC4R variant, who had a higher risk of hypertension compared to noncarriers.
A KAIST research team has developed a highly sensitive, wearable piezoelectric blood pressure sensor for continuous health monitoring. The sensor's accuracy meets international standards, with errors within ±5 mmHg and a standard deviation under 8 mmHg for both systolic and diastolic blood pressure.
Researchers used a novel machine-learning technique called causal forest, which found that treating individuals with high estimated benefits provided better population health outcomes than the traditional high-risk approach. This approach targets those with high blood pressure and could lead to more effective treatment strategies.
Researchers found that higher selenium levels were associated with lower blood pressure and HDL concentration in middle-aged women. The study suggests that selenium may moderate the effect of genetic variants on MetS components, such as waist circumference.
A new study from Uppsala University found that patients can experience twice as much improvement in blood pressure by changing medication as they would by doubling their current dose. The study, involving 280 patients and testing four different blood pressure-lowering drugs, challenges the conventional strategy of recommending equally ...
The new American Heart Association scientific statement emphasizes the importance of including non-biological factors and social determinants in CVD risk assessment for women. These factors include economic stability, neighborhood safety, education level, and access to quality healthcare, which disproportionately affect women from dive...
Researchers found that timed birth strategies, including induced labor and Cesarean deliveries, can reduce the risk of at-term preeclampsia by more than half. The study analyzed over 90,000 pregnancies and suggested that this approach has huge potential for global good in maternity care.
A new UC Davis study found that high blood pressure in young adulthood is associated with lower regional brain volumes and worse white matter integrity, both factors linked to dementia. The research also showed sex differences in the negative brain changes, with men exhibiting stronger effects than women.
A systematic review of clinical trials found that strength training with moderate to vigorous intensity, two or three times a week, can significantly lower blood pressure in hypertensive patients. The study analyzed over 21,000 scientific articles and concluded that effective results appeared around the twentieth training session.
High blood pressure in children is a significant health concern, potentially leading to cardiovascular problems in adulthood. The American Heart Association recommends monitoring blood pressure levels and implementing lifestyle modifications such as a healthy diet, regular physical activity, and weight management.
High blood pressure damages specific brain regions, including the putamen and white matter areas, leading to cognitive decline and increased risk of dementia. The study uses a combination of MRI, genetic analyses, and observational data to identify these affected regions.
Exercise training after bariatric surgery alters brain networks associated with food intake and energy regulation. The study found that exercise increased connectivity between the hypothalamus and sensory areas, while decreasing links to the default mode network and salience network.
A new study published in JACC: Advances confirms that exposure to road traffic noise can elevate hypertension risk. The research analyzed data from over 240,000 people and found a robust association between road traffic noise and hypertension, even after adjusting for air pollution.
A clinical trial found that moderate salt restriction reduced blood pressure and depressive symptoms without adverse effects in patients with primary aldosteronism. The study suggests a feasible approach to improving care for these patients and may also benefit those with essential hypertension.
A recent review article highlights the significant impact of cancer on Hispanic patients and their caregivers, citing communication barriers, financial difficulties, and sociocultural issues. The study estimates 126,000 new cancer cases diagnosed yearly in Hispanics, placing a substantial burden on family members and friends.
Three real-world studies published in the Journal of Hepatology and JHEP Reports demonstrate that bulevirtide is well-tolerated and safe for treating chronic hepatitis delta. Long-term suppressive therapy with BLV monotherapy has the potential to reduce viral replication and improve liver function in difficult-to-treat patients.
Research found that pregnancy complications such as preterm delivery, hypertensive disorders, and gestational diabetes are associated with increased risk of mortality. Women who experienced these complications had a higher risk of all-cause mortality, with some complications linked to specific causes of death like cardiovascular diseases.
A recent study published in JAMA demonstrates the effectiveness of a minimally invasive procedure called renal denervation (RDN) to treat uncontrolled hypertension. RDN uses ultrasound energy delivered through a small balloon to denervate the renal artery, reducing sympathetic nerve activity and decreasing blood pressure.
Children from low-income neighborhoods are more likely to develop preventable heart disease due to high blood pressure, according to a new study. The research highlights the importance of considering neighborhood-related factors when diagnosing hypertension in youth.
A new study found that pregnancy complications, such as high blood pressure and preterm delivery, can increase the risk of death in decades following childbirth. The research tracked data from over 46,000 people born between 1959 and 1966, revealing a significant association between these complications and increased mortality rates.
A Kaiser Permanente study of over 800,000 children aged 3-17 found that youth with higher BMI were at a 26% increased risk of developing hypertension. The study highlights the importance of preventing hypertension in young people to avoid irreversible organ damage.
A remote hypertension program, operated by Mass General Brigham, successfully supported patients through the COVID-19 pandemic in achieving their blood pressure goals. Participants who enrolled during the pandemic reached and maintained their goal blood pressures an average of two months earlier than in the pre-pandemic period.
A phase two trial found that exenatide significantly reduced brain pressure and monthly headaches in seven patients with Idiopathic Intercranial Hypertension (IIH). The study showed a rapid action of the drug, with results indicating significant reductions in brain pressure and headache days compared to the placebo arm.
A meta-analysis of 34 studies found a significant association between autism spectrum disorder (ASD) and increased risks of developing diabetes, dyslipidemia, and heart disease. Children with ASD were more likely to develop these metabolic complications, prompting clinicians to monitor them closely.
Adolescents with blood pressure above 130/85 mmHg are at risk of premature heart damage, which doubles in prevalence over a 7-year period. The study found significant differences in heart damage risks between males and females.
Research suggests that females are more prone to salt sensitivity, leading to higher blood pressure, particularly after menopause. Salt sensitivity affects about half of hypertension cases and is often linked to treatment-resistant hypertension.
A new study published in Hypertension journal found that irregular sleep patterns contribute to higher blood pressure among teens with extra belly weight. The research suggests that maintaining a regular sleep schedule may help protect adolescents from cardiovascular consequences of obesity.
A new study published in PLOS ONE found that weight loss surgery significantly improved health outcomes for people with type 2 diabetes and morbid obesity. After 12 months, patients experienced a 24% decrease in body weight and a 24% improvement in blood glucose levels.
A study of nearly 13,000 young US adults found rising diabetes and obesity rates, while hypertension remained stable. The data reveal a high burden of cardiovascular risk factors among this demographic, with Black, Hispanic, and Mexican American individuals disproportionately affected.
Research reveals obesity increases risk of diabetes and hypertension more significantly in women, with weight loss effective in reducing disease risk. However, merely losing weight is insufficient for reducing dyslipidemia in women, highlighting the need for lifestyle improvement guidance and treatment.
Researchers found that self-perceived interpersonal racism in employment, housing, and police interactions was associated with a 26% higher risk of coronary heart disease among Black women. The study analyzed data from the largest follow-up study on the health of Black women in the US.
A study published in Neurology found that high blood pressure disorders during pregnancy are associated with an increased risk of cognitive problems later in life. Those with preeclampsia may face a higher risk of cognitive decline compared to those with gestational high blood pressure.
A new study found that an ultrasound device consistently reduced daytime ambulatory blood pressure by an average of 8.5 points among middle-aged patients with hypertension. The device targets overactive nerves in the kidneys, disrupting signals that lead to high blood pressure.
A new study found that Black women of childbearing age are twice as likely to have uncontrolled high blood pressure as their white peers, increasing their risk of heart-related complications during pregnancy. Food insecurity was also a significant issue among Black and Hispanic women, with one in four experiencing food insecurity.
A recent study found that adverse pregnancy outcomes are largely driven by pre-pregnancy health issues such as diabetes and hypertension. The rate of hypertensive disorders of pregnancy rose by over 50% during the decade, while the shift in age distribution accounted for less than 2% of that change.
Researchers found that immune cells play a key role in hypertension, weakening blood vessel walls and damaging the blood-brain barrier. Inhibiting inflammatory messengers may be a new therapeutic target for treating hypertension.
A new study has confirmed that people living with HIV who switch from efavirenz to dolutegravir may gain more weight and have a higher risk of developing high blood pressure. The study found that patients on dolutegravir gained an average of 1.78 kg in 12 months, compared to those on efavirenz.
A recent study finds a strong association between hypertensive disorders of pregnancy and an increased risk of coronary artery disease and stroke. The study suggests that hypertensive disorders in pregnancy can be classified as risk factors for cardiovascular disease, highlighting the importance of prenatal care.