Articles tagged with Hypertension
A phase I clinical trial has shown that infusions of cardiosphere-derived cells are safe and may improve cardiopulmonary health in people with pulmonary arterial hypertension. The study found encouraging changes in heart function and walking distance in patients who received the treatment.
Researchers from Tokyo Medical and Dental University found that people admitted to the hospital for acute hypertension are increasingly likely to need urgent kidney dialysis or die in the hospital. The study's lead author notes that patients with certain traits, such as being younger, male, or overweight, are high-risk groups.
A multicenter observational cohort study found that cannabis exposure was associated with a higher risk of small-for-gestational-age birth, medically indicated preterm birth, stillbirth, and hypertensive disorders of pregnancy. The risk was particularly pronounced among those who continued to use cannabis beyond the first trimester.
A phase 3 trial found that tirzepatide promotes additional weight loss and preserves metabolic health when continued, but discontinuation leads to significant weight regain. Researchers suggest chronic treatment may be necessary for sustained weight loss and improved cardiometabolic risk factors.
A new study published in the Journal of the American Heart Association found that many couples around the world share high blood pressure. The research analyzed data from over 50,000 couples in four countries and found a strong association between partners' blood pressure status.
A new study provides practical guidance for implementing governance for sharing EHR data for chronic disease surveillance, which could reduce delays and provide more accurate metrics. The approach has already shown success in the Multi-State EHR-Based Network for Disease Surveillance.
A new study found that in many older couples, both husband and wife had high blood pressure in the U.S., England, China, and India. This association was stronger in collectivist societies like China and India, where couples are expected to depend and support each other emotionally and instrumentally.
Research suggests visfatin stimulates membrane raft clustering, leading to NLRP3 inflammasome activation and podocyte injury. The study highlights the role of membrane raft redox signaling in visfatin-induced inflammation and kidney damage.
A National Institutes of Health-supported study found that Hispanic/Latina women with a history of hypertensive disorders of pregnancy are more likely to have abnormalities in their heart structure and function decades later. The study suggests that having high blood pressure later in life contributes less to these changes than the his...
Researchers at Weill Cornell Medicine found that controlling high blood pressure may not prevent cognitive declines due to immune protein IL-17. Increased levels of IL-17 in the brain suppressed blood flow and induced cognitive impairment in a preclinical model.
A study found that immune cells in the meninges release IL-17, which activates inflammation and fights off infections, leading to cognitive decline. Targeting overactive T cells may be a new approach to treating hypertension-induced dementia.
A secondary analysis of a randomized clinical trial found that cardiovascular disease mortality was similar among individuals with hypertension receiving diuretics, calcium channel blockers, or ACE inhibitors. However, ACE inhibitors were associated with an increased risk of stroke outcomes by 11% compared to diuretics.
A recent study published in Circulation: Genomic and Precision Medicine reveals that genetics significantly contribute to the sex differences in hypertension development. The research found that females with high genetic risk scores had a higher risk of hypertension compared to males, while low-risk females had a lower risk than males.
Two large studies found that people with ADHD who take medication for a long time and in higher doses are at a higher risk of developing some cardiovascular diseases. The highest rate of discontinuation occurred among 18 to 19-year-olds, highlighting the need for better transition to adult psychiatry services.
A study published in Annals of Internal Medicine reveals a stagnation in cardiovascular health trends among middle-aged adults, with low-income individuals facing higher rates of hypertension and other risk factors. The research highlights the need to address social determinants of health contributing to these disparities.
A study of 278,000 individuals in Sweden found that longer cumulative duration of ADHD medication use was associated with an increased risk of hypertension and arterial disease. Clinicians should regularly monitor cardiovascular signs and symptoms during long-term treatment.
Researchers have identified a new therapeutic target for pulmonary hypertension treatment by discovering an epigenetic pathway mediated via the protein SPHK2 that can reduce and potentially reverse vascular remodeling. This discovery offers new hope for treating pulmonary hypertension, which is a complex and often fatal condition.
A study of over 20,000 middle-aged US adults found lower income status linked to increased hypertension risk. Higher-income adults faced rising rates of diabetes and obesity. Targeted public health initiatives are needed to address growing cardiovascular mortality among middle-aged adults.
A new study reveals that younger people are more vulnerable to the effects of high blood cholesterol and hypertension, atherosclerosis can be reversed if risk factors are controlled early enough. The study suggests aggressive control of cardiovascular risk factors at younger ages.
A large Asian cohort study identified systolic blood pressure targets below 130 mmHg and diastolic targets between 80-89 mmHg as key to reducing cardiovascular mortality. The findings underscore the need for cautious blood pressure management in patients with diabetes.
Researchers found that higher alcohol consumption is associated with biological age acceleration and hypertension in middle-aged and older adults, but not in young adults. The study suggests that alcohol consumption may mediate the association between alcohol intake and quantitative traits like hypertension.
A new strategy that trains healthcare providers to deliver team-based care has been found to significantly lower blood pressure in low-income patients compared to usual care methods. Patients treated by the multi-faceted approach saw a mean systolic blood pressure drop of 16 mmHg, while those in the usual care group saw a 9 mmHg drop.
A three-year intensive treatment strategy to lower systolic blood pressure below 120mmHg significantly reduced cardiovascular events, including heart attack, stroke, and death, compared to standard treatment. The study found that participants in the intensive group experienced fewer major vascular events and deaths over a two-year period.
A four-year blood-pressure intervention significantly reduced the risk of developing dementia among adults with high blood pressure, compared to those who received usual care. The study found that lowering systolic blood pressure to less than 130 mm Hg and diastolic blood pressure to less than 80 mm Hg reduced dementia risk.
A study found that pregnant women with high blood pressure who received tight blood pressure control immediately after pregnancy had lower blood pressure levels and improved cardiac function compared to those with usual care. This could lead to a reduced risk of cardiovascular disease, including heart attacks and strokes.
A single dose of zilebesiran safely and effectively lowered systolic blood pressure in people with mild-to-moderate high blood pressure for up to six months. The study found significant reductions in daytime and nighttime systolic blood pressure, as well as low rates of adverse events.
A new study from Northwestern University and Vanderbilt University Medical Center found that reducing sodium intake by just one teaspoon a day can lower systolic blood pressure by about 6 millimeters of mercury, comparable to the effect produced by commonly used first-line medication for high blood pressure. The study involved middle-a...
A study from Vanderbilt University Medical Center found that reducing sodium intake by just one teaspoon a day can lower systolic blood pressure by about 6 millimeters of mercury. Most people, regardless of whether they are already on blood pressure medications or not, can see a reduction in their blood pressure if they lower the sodiu...
A randomized clinical trial found that self-monitoring and physician-guided titration of antihypertensive medications reduced postpartum blood pressure compared to usual care. The study involved 220 participants in the UK and showed promising results for long-term blood pressure control.
A study of 213 participants found that reducing dietary sodium significantly lowered blood pressure, with consistent results across subgroups. The decline in blood pressure was also not associated with excess adverse events.
Two preliminary studies presented at American Heart Association’s Scientific Sessions 2023 found a potential association between regular marijuana use and an increased risk of heart failure, heart attack, and stroke. Daily marijuana use was associated with incident heart failure in a study involving over 150,000 adults in the US.
Two reproductive health conditions, polycystic ovary syndrome and dysmenorrhea, are linked to increased cardiovascular disease risk in women. Studies suggest that girls with polycystic ovary syndrome have a 30% higher risk of high blood pressure, while women with dysmenorrhea are twice as likely to experience ischemic heart disease.
Research highlights significantly higher heart attack death rates among American Indian and Alaska Native adults, particularly at younger ages. The study suggests that factors like limited healthcare access, socioeconomic conditions, and restricted health insurance coverage may contribute to these disparities.
A study found that physicians who presented treatments for obesity as good news and an opportunity were more successful in helping patients lose weight. Patients who received counseling with a positive and optimistic tone had significantly higher weight loss outcomes compared to those who received neutral or negative advice.
A recent study has found that transgender adults living in rural areas of the US are more likely to have cardiovascular disease risk factors such as tobacco use, obesity, and high blood pressure. The research highlights the need for targeted interventions to reduce health disparities among this population.
The American Heart Association has selected five finalists in its 6th annual Health Tech Competition to present their innovative technologies. The competition aims to drive technology innovation and transform the landscape of heart and brain health.
A VCU-led study found that pharmacists' ability to treat patients with hypertension could prevent millions of heart attacks, strokes, and other cardiovascular events. The study estimates a cost savings of $1.1 trillion over 30 years, with significant economic and quality-of-life impacts.
A study led by Brown University researchers found that mindfulness-based blood pressure reduction programs improve health behaviors associated with lower blood pressure. Participants in the program showed significant improvements in adherence to a heart-healthy diet and self-awareness, which influences dietary choices.
A new study from Tulane University found that frequent salt consumption is associated with a higher risk of developing Type 2 diabetes. The study surveyed over 400,000 adults and found participants who regularly added salt had a 13% to 39% increased risk of developing the disease compared to those who never or rarely used salt.
Dr. Marlene Rabinovitch, a renowned pediatric cardiologist, will receive the 2023 Research Achievement Award for her groundbreaking research on PAH treatment. Her discoveries have led to the identification of neutrophil elastase as a trigger for inflammatory responses and the potential use of immunosuppressant FK506 to restore lung blo...
The study analyzed global data from the past three decades, revealing an overall increase in hypertensive heart disease (HHD) prevalence but a decrease in mortality and disability-adjusted life years (DALYs). The burden of HHD is particularly concerning for healthcare systems due to higher prevalence with lower mortality rates.
A 32-year study of 820 adults found high blood pressure variability in late life increased dementia risk, but had little effect on midlife risk. The results suggest blood pressure variability may be a key indicator of dementia risk in older age.
Researchers at The University of Toledo discovered that engineered Lactobacillus paracasei can lower blood pressure in female rats by introducing human ACE2. The study provides a paradigm shift in harnessing the body's microbiome to regulate blood pressure and offers new hope for treating chronic conditions.
Recent studies suggest that probiotics may offer a protective effect against hypertension, but the exact mechanisms are unclear. A new study identifies two probiotic strains, Bifidobacterium lactis and Lactobacillus rhamnosus, as promising treatments for high blood pressure.
A new study finds that short and long-term blood pressure fluctuations increase the risk of dementia and vascular problems in older people. Higher systolic BP variations are also linked with stiffening of the arteries, a key factor in heart disease.
A study by researchers from National Institutes of Health and Glasgow University found that amlodipine does not activate calcium channels, contradicting earlier concerns. The medication remains a recommended first-line treatment for high blood pressure, reducing deaths from hypertension.
A clinic-based community program improved food security scores, healthy eating behaviors, and depression scores in a vulnerable, food-insecure population. The Geaux Get Healthy Clinical Program provided comprehensive education and access to resources, leveraging community partnerships.
A new study analyzing English primary care records found that hypertension, obesity, diabetes, and low HDL cholesterol confer a higher risk of dementia in South Asian and Black people compared to White individuals. The results suggest tailored dementia prevention efforts should be targeted towards minority ethnic groups.
Having obesity before and during early pregnancy is linked to adverse outcomes like high blood pressure, preeclampsia, and gestational diabetes. These complications account for a small percentage of increased cardiovascular disease risks in the years following pregnancy for people with obesity.
A new study found that pre-pregnancy obesity is a primary driver of future cardiovascular disease risk, rather than pregnancy complications. The research followed 4,216 individuals from early pregnancy to postpartum and found those with overweight or obese BMI had a higher risk of developing hypertensive disorders during pregnancy.
Research reveals that faster placental growth increases the risk of preeclampsia and shorter pregnancy duration. Genetic variations affecting placental size also influence baby weight and mother's health.
A new study led by UCL researchers finds that integrated health care for chronic high-burden conditions like diabetes and hypertension is feasible and cost-effective. The study showed that integrated care was associated with high levels of retention in care, no adverse effect on viral suppression among people with HIV, and cost-saving ...
Research suggests that trans men and women have a higher risk of cardiovascular disease, while the link to diabetes remains uncertain. Testosterone therapy may contribute to increased cardiovascular risk in trans men, whereas hormone treatments for trans women do not explain this association.
A large public health survey in rural South Africa found that approximately half of people living with HIV, diabetes or hypertension have unmet health needs. The study's novel framework quantifies met and unmet health needs for individuals living with infectious and non-communicable diseases.
Researchers analyzed UK data to identify patterns of illnesses in individuals leading up to a type 2 diabetes diagnosis. High blood pressure, respiratory tract infections, heart conditions, and asthma were commonly observed, suggesting earlier diagnosis may be possible.
A study published in Diabetes Care found that obesity, hypertension, and dyslipidemia alter cardiac energy production by interfering with metabolic substrate uptake. The research reveals early changes in apparently healthy middle-aged individuals, highlighting the importance of identifying mechanisms involved in heart disease onset.
A real-world study confirms the reliability and effectiveness of the Pooled Cohort Equation (PCE) in assessing cardiovascular risk, regardless of statin use. The PCE performed well across different demographics and retained accuracy with measurement factors outside its original risk profile range.
A new study from Brigham researchers reveals that women who struggle with getting enough sleep are at greater risk of developing hypertension. The research highlights the association between sleep difficulties and higher BMI, lower physical activity, and poorer diets.
A study by UC San Francisco researchers found that patients with acute kidney injury on outpatient dialysis may not need lifelong treatment if they have the potential to recover. The study tracked data from over 1,700 patients and showed that approximately three-quarters of those who recovered kidney function discontinued dialysis with...
A recent study found that adding 3000 steps per day can significantly reduce high blood pressure in older adults. The study involved sedentary adults aged 68-78 who walked an average of 4000 steps before the intervention, resulting in a 7-point decrease in systolic and 4-point decrease in diastolic blood pressure.