Articles tagged with Hypertension
A low-dose triple-pill protocol demonstrated improved blood pressure lowering and control, with good tolerability, compared to standard-care protocols for Black African adults with uncontrolled hypertension. The study results have significant implications for hypertension treatment in Nigeria.
A novel low-dose 3-in-1 blood pressure pill (GMRx2) significantly reduces blood pressure in patients with uncontrolled hypertension. After six months treatment, the GMRx2 group achieved a 5.8mmHg lower systolic blood pressure compared to standard care.
The new guidelines recommend intensified BP targets, introducing a novel elevated blood pressure category to identify individuals at risk for cardiovascular disease. The updated recommendations also focus on 'frailty' rather than chronological age and introduce a new systolic BP treatment target range of 120-129 mmHg.
After three decades, perioperative mortality rates for living kidney donors have decreased substantially, from fewer than 1 event per 10,000 donations in the past decade to even lower numbers. Donor demographics, such as male donors and those with a history of hypertension, are identified as high-risk groups.
This study found that higher hypertension rates among Black adults persisted across levels of socioeconomic disadvantage. Living in socioeconomically disadvantaged neighborhoods was associated with higher hypertension rates among people of all racial and ethnic backgrounds.
A UCLA-led study has identified a protective role for the asporin protein in pulmonary arterial hypertension (PAH), suggesting potential new ways to treat this incurable disease. Asporin was found to inhibit pulmonary artery smooth muscle cell proliferation and a key signaling pathway that occurs with PAH.
Researchers analyzed national Medicaid data to identify perinatal and postpartum outcomes among people with intellectual and developmental disabilities. Autistic pregnant people had significantly higher probability of postpartum anxiety and postpartum depression compared to other groups.
A meta-analysis of 31,250 people found that those with untreated high blood pressure had a 36% increased risk of Alzheimer's disease compared to those without the condition. Taking blood pressure medication was associated with decreased risk of Alzheimer's disease throughout later life.
A five-year randomized control trial found that diets high in fruits and vegetables lower blood pressure, reduce cardiovascular risk, and improve kidney health. The study also suggests that incorporating fruits and vegetables into treatment plans can be more effective than traditional medication approaches.
Uncontrolled hypertension is a leading cause of premature death and disability worldwide, with 54% of patients aware but only 21% actively controlled. Effective treatment requires lifestyle changes and medication, as well as regular blood pressure monitoring to adjust doses accordingly.
A new study suggests that public health interventions, such as reformulating food products and introducing low emission zones, could yield significant cost savings and QALY gains in England. The interventions studied could save up to £4bn by reducing dementia rates and helping people live longer and healthier.
A recent study published in Environment International found that high levels of tellurium exposure are associated with increased blood pressure and a greater occurrence of hypertension. Tellurium, a contaminant transferred from mining and manufacturing activities, can be present in foods such as cereals and legumes.
The AHA PREVENT equations could reduce eligibility for statin and antihypertensive therapy among 15.8 million US adults due to lower atherosclerotic cardiovascular disease risk predictions. This change may impact treatment guidelines and recommendations.
Rates of hypertensive disorders of pregnancy increased from 6.1% to 8.5%, while related health conditions declined, according to a Canadian study. The growing population of high-risk obstetrical patients highlights the need for easily accessible specialized care.
A new University of Michigan study found that over 82% of Americans aged 50-80 take one or more prescription medications, with 80% open to stopping certain drugs. However, researchers stress the importance of personalized guidance for deprescribing older adults, particularly those taking medication for cardiovascular disease or diabetes.
A recent study at the University of Missouri discovered that oxytocin and corticotropin-releasing hormone cause the brainstem to become overactive, leading to hypertension. This finding can help develop targeted drugs to reduce high blood pressure in sleep apnea patients.
A study published in JAMA Network Open found that years of high systolic blood pressure increase the risk of stroke, with Black and Hispanic patients facing a higher risk. Early diagnosis and controlled high blood pressure are crucial to preventing stroke, especially in these populations.
A new study has identified CCL27 and TNFRSF14 as genetic markers in inflammation that may contribute to stroke recurrence. These findings could lead to novel drug targets to mitigate disability and mortality after a first stroke.
A Tulane University study found that pharmacists have the best success rates in helping patients with high blood pressure get their hypertension under control. Pharmacists achieved the greatest improvements, followed by community health workers, who also saw significant reductions in blood pressure.
A Texas A&M University study found that stand-biased workstations led to more standing time, reduced sitting time, and fewer discomforts compared to traditional desks. However, the benefits were not statistically significant, and energy expenditure was higher in stand-biased groups.
Splenic venous hypertension is a rare condition characterized by upper GI bleeding without liver disease. It arises due to increased pressure in the splenic vein, leading to gastric varices. Diagnosis involves clinical suspicion, imaging studies, and endoscopic methods.
A new study published in Hypertension journal suggests that both 30-year and 10-year risk predictions should be considered when making high blood pressure treatment decisions. The researchers compared two risk prediction tools and found that long-term, 30-year risk may be more important than short-term, 10-year risk for informing medic...
A new study suggests that lowering systolic blood pressure below 120 mmHg over time may produce slight health-protective benefits against late-life dementia. The study found that middle-aged adults who lower their systolic blood pressure, particularly Black and Latino individuals, had a reduced risk of developing dementia.
A Swedish researchers have created a questionnaire test that quickly identifies individuals at high risk of heart attack. The test has been shown to be as accurate as blood tests and blood pressure measurements, detecting 65% of those at the highest risk of cardiovascular disease.
Researchers found that facial temperatures are associated with chronic illnesses like diabetes and high blood pressure. They discovered specific regions of the face where temperatures correlate with age and health, including the nose, eyes, and cheeks.
A new study led by UCL researchers found that cardiovascular health is a significant risk factor for future dementia rates. The study analyzed data from 27 papers and found that rates of obesity and diabetes have increased over time, contributing to higher dementia risk.
A study found that a cuffless wrist monitor provides hundreds of readings in days, enabling clinicians to determine cardiovascular risk and improve hypertension care. The device's continuous readings help confirm diagnosis and guide medication titration, potentially revolutionizing hypertension management.
The HHS competition evaluated Ochsner Connected MOM's effectiveness in increasing blood pressure measurements among Black patients and rural populations. The program saw a statistically significant increase in blood pressure measurements, benefiting over 2,000 patients.
Researchers created an integrated cellular map of a mouse model heart, pinpointing cells and pathways involved in fibrosis. The study identified myofibroblasts as the major drivers of scarring, but also discovered a 'matrifibrocyte' form that may prevent scar resolution.
A large international study of 1,042 living kidney donors found no significant differences in health indicators compared to non-donors seven years after donation. The study also provides insights into recovery time from living kidney donation, suggesting a longer recovery period than previously thought.
Research published in the European Heart Journal found that women diagnosed with perinatal depression are more likely to develop cardiovascular disease. The study included data from around 600,000 women and found a strong link between perinatal depression and risks of high blood pressure, ischemic heart disease, and heart failure.
A new study found that regular snoring is associated with elevated blood pressure and uncontrolled hypertension, particularly in overweight middle-aged men. The research used multiple night home-based monitoring technologies and objective assessments to explore the connection between snoring and hypertension.
The number of US individuals with chronic hypertension in pregnancy increased significantly, while medication treatment remained low, according to a new study. The findings highlight the need for improved maternal health strategies to address high blood pressure and cardiovascular complications.
The prevalence of chronic hypertension in pregnancy in the US more than doubled from 1.8% to 3.7% between 2007 and 2021, despite only 60% of those with the condition being treated with antihypertensive medications. This increase is linked to rising maternal age, obesity rates, and other factors.
A global meta-analysis of 1.8m women found COVID-19 vaccination reduces the risk of infection during pregnancy by 61% and hospitalization by 94%. Vaccination also lowers caesarean section risk by 9%, hypertensive disorders in pregnancy by 12%, and intensive care unit admission for newborns by 8%.
The WISEWOMAN program, funded by the CDC, improved blood pressure, diet, and physical activity among low-income, uninsured women in Nebraska. Lifestyle interventions led to significant weight loss, increased fruit and vegetable consumption, and improvements in cardiovascular disease risk factors.
A new study from Wake Forest University School of Medicine suggests that vigorous physical activity can lower the risk of cognitive decline in high-risk patients with hypertension. People who engage in one or more sessions of vigorous exercise per week had lower rates of mild cognitive impairment and dementia.
A recent study from the Women's Health Initiative found that both obesity and metabolic syndrome increase breast cancer risk, but in distinct ways for different subtypes. The research highlights the importance of controlling waist circumference and metabolic conditions to reduce breast cancer risk.
A substantial portion of young athletes are at risk of hypertension, with 21.3% meeting pre-HTN criteria and 8% diagnosed with Stage II HTN. Lifestyle interventions and screening for hypertension are crucial to prevent long-term health complications.
Low-income Black and Hispanic stroke survivors with uncontrolled hypertension experienced a more than two-fold reduction in blood pressure when tracked at home and sent readings to a nurse. Nurse case management enhanced telehealth programs showed significant benefits for this vulnerable population.
A study found that higher phthalate exposure is associated with increased risk of preeclampsia and eclampsia in pregnant women. Pregnancies involving female fetuses are more susceptible to these hypertensive disorders.
Researchers discuss Ibrutinib, a BTK inhibitor approved for chronic lymphocytic leukemia treatment, noting 20-25% of patients experience dose-limiting cardiovascular toxicities. A recent study identifies genetic biomarkers, such as KCNQ1 and GATA4, associated with cardiotoxic events, which may improve risk stratification.
By 2050, at least 61% of US adults (184 million people) are projected to have some type of cardiovascular disease, with total costs tripling to $1.8 trillion. Population shifts, high blood pressure, and obesity will drive this increase.
A new study found that people exposed to higher levels of airplane noise were more likely to have a higher body mass index, an indicator for obesity that can lead to cardiometabolic diseases. The study highlights the role of environmental factors in shaping health outcomes.
A new study shows that a fully digital, AI-based lifestyle coaching program can effectively reduce blood pressure in adults with hypertension. The program, which leverages data from wearable activity trackers and BP monitors, also increases participant engagement and reduces the need for manual clinician outreach.
After living kidney donation, donors experience a slower rate of estimated glomerular filtration rate (eGFR) decline compared to non-donors. However, donors are more likely to have an eGFR between 30-60 mL/min/1.73 m2 at least once during follow-up.
A study of 23 elderly patients with hypertension found that evening aerobic exercise improved baroreflex sensitivity, a mechanism that regulates blood pressure. This improvement led to better blood pressure regulation and reduced muscle sympathetic nerve activity, making evening exercise more effective than morning exercise.
A new study found that very early blood pressure lowering treatment can improve outcomes for patients with intracerebral hemorrhage, but worsen outcomes for those with ischemic stroke. Rapid diagnosis of the type of stroke is crucial in harnessing the benefits of this treatment.
Research suggests that taking antihypertensive medications at times aligned with personal chronotype could reduce the risk of heart attacks. Morning larks and night owls who took their medications in sync with their natural rhythms had lower rates of cardiovascular events compared to those who took them at odds with their chronotypes.
A recent NIH-funded study found that adverse social determinants of health are linked to treatment-resistant hypertension in Black Americans. The risk was higher among Black adults than white adults, with factors including lower education and income levels contributing to the disparity.
The Global Burden of Diseases study reveals a 49.4% increase in global disability-adjusted life years (DALYs) attributable to metabolism-related risk factors between 2000 and 2021. High blood pressure, high blood sugar, and high BMI are key contributors to poor health and early death.
Clear sociodemographic disparities were identified in patient portal engagement among patients with hypertension treated in primary care. Without targeted interventions, patient portals may exacerbate existing health disparities.
A recent analysis of WHI findings indicates that MetS and obesity each have different associations with breast cancer subtypes and mortality risk. Women with higher MetS scores are at a higher risk of poor-prognosis, estrogen receptor-positive, progesterone receptor-negative breast cancers.
A secondary analysis of a randomized clinical trial found that home blood pressure self-monitoring plus medication self-titration reduces BP in the longer term without increasing healthcare use or adverse events. This simple, inexpensive intervention has potential to improve long-term hypertension control in routine clinical practice.
In Brazil, deaths from diabetes and hypertension have increased significantly since 2020, even after excluding those linked to COVID-19. This persistent trend highlights the need for continued efforts to address these major public health concerns.
Research suggests long-term exposure to PM1 particulate matter increases risk of hypertension hospitalization, with significant effects observed for females and in areas exceeding air quality guidelines. The study's findings support the importance of controlling PM1 pollution and protecting vulnerable populations.
A study published in JAMA Pediatrics reveals that children diagnosed with hypertension are at a higher risk of major adverse cardiac events later in life. Improved detection, follow-up, and control of pediatric hypertension may reduce the risk of adult cardiovascular disease.
A new screening algorithm combining maternal history, ultrasound data and several tests for blood markers may predict most preeclampsia cases in the first trimester of pregnancy. The study found that personalized risk-based treatment decisions may improve adherence to preventative measures.
Researchers will discuss key findings on pediatric mental health, vaccination, autism diagnosis, social determinants of cardiovascular health, and treatment of bronchiolitis. Studies examine the relationship between socioeconomic factors and hypertension in youth, long wait times for autism evaluations, and the impact of HPV vaccine up...
A team of researchers has developed a hemostasis sponge that swiftly staunchs kidney bleeding and facilitates wound recovery. The material uses kidney-derived decellularized extracellular matrix to recreate the kidney's microenvironment, boasting high biocompatibility.