A new study found that fasting hyperglucagonemia in type 2 diabetes is associated with higher waist-to-hip ratio, poor glycemic control, and increased insulin concentrations. Visceral fat deposition may play a role in the development of this condition.
QUT researchers have discovered a drug that prevents laminitis in ponies with equine metabolic syndrome. The drug, velagliflozin, works by causing the kidneys to excrete more glucose in the urine, taking pressure off the pancreas and lowering insulin levels.
Researchers will investigate molecular methods to identify resistant parasites, develop new tests for metabolic syndrome diagnosis, and explore the role of gut bacteria in the disease. The studies may lead to improved equine health outcomes and new interventions.
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Research finds cardiorespiratory fitness, high-intensity physical activity and low sedentary time all lower type 2 diabetes risk. The study, published in Diabetologia, suggests that a combination of these traits may be more beneficial than individual components.
A study published in PLOS ONE found that restricting high-sucrose diet to active times reduced fat levels in rats. The research team limited the diet to nighttime, resulting in lower blood and liver fat compared to an unrestricted diet.
The Eat, Love, Move (ELM) program will be expanded to six cities across the US after a successful two-year pilot project at Rush University Medical Center. The six-year, $9 million grant aims to determine whether lifestyle changes can reverse metabolic syndrome and improve quality of life.
A survey of women with polycystic ovary syndrome (PCOS) reveals distrust in healthcare providers and a lack of emotional support as major contributing factors to negative medical experiences. Women with PCOS often wait years for diagnosis and receive limited information about the disorder, leading to arguments with physicians.
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Researchers compared CF-PWV and CAVI to assess vascular ageing, finding CAVI provides additional information on vessel wall state. Metabolic syndrome was found to increase CF-PWV levels but not affect CAVI.
A large Korean study found that sleeping fewer than six hours a day is associated with an increased risk of metabolic syndrome and its components, including higher waist circumference and triglycerides. The study also showed a potential gender difference, with long sleep linked to metabolic syndrome in women and short sleep in men.
A new computational model accurately predicts the gradual progression of metabolic syndrome in mice, identifying two disease subtypes and their underlying metabolic differences. The model also correctly predicts comorbidities like fatty liver disease, offering new insights into preventing the disease.
A new study found that nearly half of people with metabolically healthy obesity (MHO) developed metabolic syndrome within 10 years, increasing their risk for cardiovascular disease and diabetes. MHO is defined as a body mass index of more than 30 and two or fewer risk factors.
Researchers found that S597 slows progression of atherosclerosis in mice with metabolic syndrome by reducing inflammation and immune cell activity. The peptide lowers blood sugar levels without preventing atherosclerosis, offering a novel treatment strategy for protecting against advanced cardiovascular disease.
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A Johns Hopkins study of mice with metabolic syndrome found that the intestinal microbiome plays a substantial role in the development of obesity and insulin resistance. The research suggests that manipulating gut bacteria may prevent obesity and diabetes.
A recent study found that yoga exercise decreases pro-inflammatory adipokines and increases an anti-inflammatory adipokine in adults with metabolic syndrome. This suggests that regular exercise, such as yoga, can help manage aspects of the condition by reducing chronic inflammation.
Researchers at Oregon State University discovered that compounds derived from hops can improve glucose intolerance, insulin resistance, and sensitivity to leptin in people with metabolic syndrome. The findings suggest that these compounds may be a promising treatment option for the condition.
A large retrospective study found that obese men and those with metabolic syndrome had a higher risk of biochemical recurrence after radical prostatectomy. Patients with obesity had a 32% higher chance of recurrence compared to those with normal weight, while those with metabolic syndrome had over four-fold increased risk.
Research reveals exposure to air pollution during high school is correlated with menstrual cycle irregularity, potentially affecting reproductive health. The findings suggest reducing emissions could mitigate human disease implications.
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A study led by Georgia State University found that dietary fiber inulin prevented metabolic syndrome by restoring gut microbiota levels, increasing intestinal epithelial cell production, and regulating interleukin-22 expression. This study suggests that fermentable fibers like inulin may promote better health by suppressing obesity and...
A USC study suggests that regular exercise can lower breast cancer survivors' risk of cardiovascular disease, Type 2 diabetes, and breast cancer recurrence. Exercise helps reduce inflammation, improves heart health, and increases good cholesterol levels.
Researchers found that individuals with Metabolic Syndrome were more likely to experience chronic and severe depression symptoms, requiring longer treatment response times. The study emphasizes the importance of healthcare providers closely monitoring older adults with Metabolic Syndrome when screening for and treating depression.
Researchers found that college graduates from minority groups exhibited lower rates of depression than non-graduates, despite experiencing socioeconomic disadvantages in childhood. However, black and Hispanic college graduates showed higher rates of metabolic syndrome compared to their noncollege counterparts.
A new study from the University of North Carolina at Chapel Hill reveals that black and Hispanic young adults from disadvantaged childhoods face worse physical health risks despite completing college. College completion is linked to improved mental health, but not necessarily better physical health outcomes for minority individuals.
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Researchers have identified a three-molecule signature that accurately indicates insulin resistance, or pre-diabetes, in mice. This discovery could enable earlier detection of pre-diabetes in humans and tailor healthcare treatments to individual patients' needs.
A study presented at the American Heart Association's Scientific Sessions 2017 found that fast eaters were more likely to develop metabolic syndrome, a cluster of heart disease, diabetes, and stroke risk factors. Eating slowly was also associated with lower weight gain, higher blood glucose regulation, and a smaller waistline.
Regular consumption of sugar-sweetened beverages like soda and juice is associated with an increased risk of developing type 2 diabetes and metabolic syndrome. A review of 36 studies found that frequent intake of these beverages contributes to the onset of cardiometabolic diseases, including high blood pressure and heart disease.
The study investigates stevia's antiobesity, antihyperglycemic, antihypertensive, and antihyperlipidemic effects. Stevia extracts derived from the plant's leaves, flowers, and roots may provide natural alternatives for treating metabolic syndrome-related disorders.
African-American teens who lived through the Great Recession of 2007-2009 may be at higher risk for metabolic syndrome, a cluster of risk factors for heart disease and diabetes. The study found that those in poverty were more likely to develop this condition, highlighting the impact of economic downturns on young people's health.
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Research examines how gastric emptying rates affect postprandial glucose levels and incretin hormone secretion. The study reveals the gastrointestinal tract's contribution to insulin regulation in individuals with type 2 diabetes.
A clinical trial found that an Alzheimer's medication, galantamine, reduces inflammation and insulin resistance in patients with metabolic syndrome. The study showed a 25% decrease in inflammatory markers and improved insulin levels.
A study published in The Lancet Diabetes & Endocrinology found that diabetes prevalence is increasing among low socio-economic backgrounds living in urban areas of affluent states in India. Diabete's rates are higher among people from low socio-economic status, especially in cities with poor access to healthcare.
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Consuming avocados may be associated with better diet quality, higher intake of essential nutrients, lower body weight, lower BMI, and smaller waist circumference. Avocado consumers also have lower insulin and homocysteine levels, as well as a reduced incidence of metabolic syndrome.
Metabolic syndrome is a cluster of risk factors including abdominal obesity, high triglycerides, and insulin resistance, increasing the risk of type 2 diabetes. Overweight and obesity contribute to metabolic syndrome, affecting 1 in 3 adults and 40% of adults aged 40 and older
Researchers found that inhaled corticosteroid use is associated with a higher body mass index (BMI) and an increased prevalence of the metabolic syndrome in women. Corticosteroid users had a 1.4-fold elevated likelihood of having the metabolic syndrome, with nearly a point higher BMI.
Researchers found that people with severe gum disease had higher HbA1C values and were more likely to have pre-diabetes or suspected diabetes. This suggests that severe gum disease may be an early sign of undiagnosed diabetes, making screening in dental practices a feasible option.
A study published in Frontiers in Physiology found that people living at higher altitudes (457-2297 meters) had a lower risk of developing Metabolic Syndrome, which contributes to heart disease and diabetes. The research suggests that high-altitude living may help improve heart and lung function, insulin sensitivity, and weight loss.
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A new model for defining healthy eating is presented in a review article, taking into account caloric load, cellular respiration, and food perception. The study aims to reduce the risk of weight gain and cardiometabolic disease by understanding the complex factors involved.
A new study by the University of Pennsylvania School of Medicine finds that internalizing negative weight stereotypes increases the risk of cardiovascular and metabolic disease in obese patients. Patients who experience fat shaming are more likely to avoid exercise, consume extra calories, and develop conditions like metabolic syndrome.
A study published in the American Journal of Clinical Nutrition found that people with metabolic syndrome require 30-50% more vitamin E than healthy individuals. Conventional blood tests may mask underlying deficiencies due to vitamin E's attraction to high cholesterol and fat.
A new study published in Journal of Medicinal Food found that blue maize extract improved systolic blood pressure, HDL cholesterol, and triglyceride levels in rats with metabolic syndrome. The natural antioxidants present in blue maize may help protect against cardiovascular disease, diabetes, and cancer.
A systematic review of screening tests and interventions for type 2 diabetes prevention found low diagnostic accuracy, with lifestyle interventions showing a 37% reduction in relative risk. Population-wide approaches may be more effective than screen and treat policies alone.
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Researchers discovered that vitamin D deficiency contributes to metabolic syndrome progression in mice by disrupting gut bacteria balance. Vitamin D supplementation improves metabolic syndrome outcomes by recovering gut bacteria balance and reducing blood sugar levels.
A new study of U.S. adolescents has found an association between metabolic syndrome and impairments in reading, attention, and working memory. The researchers found that treatment can control and reverse metabolic syndrome, which may help reduce cognitive effects.
A new definition of pre-diabetes based on hemoglobin A1C levels can help identify individuals at high risk of developing long-term complications from diabetes. The study suggests that this more accurate predictor can encourage lifestyle changes such as weight loss and exercise, ultimately preventing the development of full-blown diabetes.
A recent study found that dolphin serum contains high levels of antioxidant protein, which may hold clues to treating aging-associated diseases in humans. Researchers also discovered 11 proteins more prevalent in dolphin serum than in human samples, including vanin-1 and adiponectin.
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Researchers at Oregon State University have identified how xanthohumol works and why it has promise in addressing high cholesterol, blood sugar, obesity, and other issues of metabolic syndrome. Xanthohumol may be used as a supplement or prescription drug to address these disorders.
A Georgia State University researcher is investigating how changes in intestinal bacteria may lead to obesity and metabolic syndrome. He aims to understand the role of dietary fiber in altering gut bacteria and promoting inflammation.
Women with polycystic ovary syndrome (PCOS) may benefit from incorporating soy isoflavones into their diets, according to a new study. The study found that consuming soy isoflavones regularly can lower levels of insulin in the blood and improve metabolic health.
Researchers found that community-based behavioral lifestyle intervention programs improve health-related quality of life by nearly 10% among participants. Those with lower baseline quality of life showed the greatest improvement, with scores increasing from 61.8 to 74 after completing the year-long program.
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A recent clinical trial found that patients with metabolic syndrome who consumed muffins enriched with safflower oil (PUFA) lost more weight and showed greater health improvements than those consuming muffins made with sunflower oil (MUFA). This is a significant finding, as the study suggests that PUFA may be a better choice for managi...
A randomized controlled trial found that black raspberry extract significantly lowers arterial stiffness, a key indicator of cardiovascular disease. The study also showed increased levels of endothelial progenitor cells, which help repair damaged arteries.
A study at Oregon State University has identified a specific intake level of xanthohumol that significantly improves metabolic syndrome markers and reduces weight gain in laboratory animals. The findings suggest a possible new approach to addressing obesity, high cholesterol and elevated glucose.
A randomized, placebo-controlled crossover clinical trial found that regular fresh pear consumption significantly lowered systolic blood pressure and pulse pressure in middle-aged men and women with metabolic syndrome. The study, led by Dr. Sarah A. Johnson, suggests pears may be a potential tool to improve cardiovascular risk factors.
Taking long naps or being excessively tired during the day is linked to a higher risk of developing metabolic syndrome, which includes high blood pressure, high cholesterol, and obesity. The study found that napping for 40 minutes or longer was associated with a significant increase in metabolic syndrome risk.
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A new study published in Nutrition and Diabetes journal found that low-carbohydrate, high-fat diets can lead to rapid weight gain and worsen glucose intolerance. The research suggests that fad diets like Paleo may not be suitable for people with pre-diabetes or diabetes.
Emerging vascular risk factors like inflammatory markers, endothelial dysfunction, and lipid disorders show gender differences. Women tend to have higher CVD risk than men, except for tumor necrosis factor-alpha and homocysteine levels.
Scientists at Gladstone Institutes discovered a novel regulator of body weight: the P75 neurotrophin receptor. Lowering levels of p75 NTR protected mice from developing obesity, diabetes, and fatty liver disease on a high-fat diet. The receptor plays a key role in regulating metabolic processes that control body weight.
Overweight and obesity are strong predictors of metabolic syndrome in menopausal women. Women who experienced menopause during the study had a higher risk if they were overweight or obese, with risks increasing by up to 12 times for those who were obese.
A study by the American Cancer Society found that standing for at least one-quarter of the day was associated with lower odds of obesity. Standing time was also linked to reduced metabolic risk, particularly when combined with physical activity.
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Researchers at Weizmann Institute discovered a subtype of immune cells that prevent metabolic syndrome by regulating inflammation-causing T cells. Mice lacking these cells became overweight and developed symptoms of metabolic syndrome.
A recent study suggests that obese individuals with metabolic syndrome may be chronically deficient in vitamin E, which is crucial for combating oxidative stress and associated diseases like heart disease and Alzheimer's. Experts recommend a balanced diet with daily multivitamins and healthy fats to mitigate this deficiency.