A systematic review of screening tests and interventions for type 2 diabetes prevention found low diagnostic accuracy, with lifestyle interventions showing a 37% reduction in relative risk. Population-wide approaches may be more effective than screen and treat policies alone.
Researchers discovered that vitamin D deficiency contributes to metabolic syndrome progression in mice by disrupting gut bacteria balance. Vitamin D supplementation improves metabolic syndrome outcomes by recovering gut bacteria balance and reducing blood sugar levels.
A new study of U.S. adolescents has found an association between metabolic syndrome and impairments in reading, attention, and working memory. The researchers found that treatment can control and reverse metabolic syndrome, which may help reduce cognitive effects.
A new definition of pre-diabetes based on hemoglobin A1C levels can help identify individuals at high risk of developing long-term complications from diabetes. The study suggests that this more accurate predictor can encourage lifestyle changes such as weight loss and exercise, ultimately preventing the development of full-blown diabetes.
A recent study found that dolphin serum contains high levels of antioxidant protein, which may hold clues to treating aging-associated diseases in humans. Researchers also discovered 11 proteins more prevalent in dolphin serum than in human samples, including vanin-1 and adiponectin.
Researchers at Oregon State University have identified how xanthohumol works and why it has promise in addressing high cholesterol, blood sugar, obesity, and other issues of metabolic syndrome. Xanthohumol may be used as a supplement or prescription drug to address these disorders.
A Georgia State University researcher is investigating how changes in intestinal bacteria may lead to obesity and metabolic syndrome. He aims to understand the role of dietary fiber in altering gut bacteria and promoting inflammation.
Women with polycystic ovary syndrome (PCOS) may benefit from incorporating soy isoflavones into their diets, according to a new study. The study found that consuming soy isoflavones regularly can lower levels of insulin in the blood and improve metabolic health.
Researchers found that community-based behavioral lifestyle intervention programs improve health-related quality of life by nearly 10% among participants. Those with lower baseline quality of life showed the greatest improvement, with scores increasing from 61.8 to 74 after completing the year-long program.
A recent clinical trial found that patients with metabolic syndrome who consumed muffins enriched with safflower oil (PUFA) lost more weight and showed greater health improvements than those consuming muffins made with sunflower oil (MUFA). This is a significant finding, as the study suggests that PUFA may be a better choice for managi...
A randomized controlled trial found that black raspberry extract significantly lowers arterial stiffness, a key indicator of cardiovascular disease. The study also showed increased levels of endothelial progenitor cells, which help repair damaged arteries.
A study at Oregon State University has identified a specific intake level of xanthohumol that significantly improves metabolic syndrome markers and reduces weight gain in laboratory animals. The findings suggest a possible new approach to addressing obesity, high cholesterol and elevated glucose.
A randomized, placebo-controlled crossover clinical trial found that regular fresh pear consumption significantly lowered systolic blood pressure and pulse pressure in middle-aged men and women with metabolic syndrome. The study, led by Dr. Sarah A. Johnson, suggests pears may be a potential tool to improve cardiovascular risk factors.
Taking long naps or being excessively tired during the day is linked to a higher risk of developing metabolic syndrome, which includes high blood pressure, high cholesterol, and obesity. The study found that napping for 40 minutes or longer was associated with a significant increase in metabolic syndrome risk.
A new study published in Nutrition and Diabetes journal found that low-carbohydrate, high-fat diets can lead to rapid weight gain and worsen glucose intolerance. The research suggests that fad diets like Paleo may not be suitable for people with pre-diabetes or diabetes.
Emerging vascular risk factors like inflammatory markers, endothelial dysfunction, and lipid disorders show gender differences. Women tend to have higher CVD risk than men, except for tumor necrosis factor-alpha and homocysteine levels.
Scientists at Gladstone Institutes discovered a novel regulator of body weight: the P75 neurotrophin receptor. Lowering levels of p75 NTR protected mice from developing obesity, diabetes, and fatty liver disease on a high-fat diet. The receptor plays a key role in regulating metabolic processes that control body weight.
Overweight and obesity are strong predictors of metabolic syndrome in menopausal women. Women who experienced menopause during the study had a higher risk if they were overweight or obese, with risks increasing by up to 12 times for those who were obese.
A study by the American Cancer Society found that standing for at least one-quarter of the day was associated with lower odds of obesity. Standing time was also linked to reduced metabolic risk, particularly when combined with physical activity.
Researchers at Weizmann Institute discovered a subtype of immune cells that prevent metabolic syndrome by regulating inflammation-causing T cells. Mice lacking these cells became overweight and developed symptoms of metabolic syndrome.
A recent study suggests that obese individuals with metabolic syndrome may be chronically deficient in vitamin E, which is crucial for combating oxidative stress and associated diseases like heart disease and Alzheimer's. Experts recommend a balanced diet with daily multivitamins and healthy fats to mitigate this deficiency.
Research suggests that gut bacteria can ferment dietary fiber, producing short-chain fatty acids that contribute to liver lipids and potentially lead to non-alcoholic fatty liver disease. In individuals with compromised TLR5 function, overconsumption of fiber may exacerbate this process.
Researchers at Marshall University have identified a novel mechanism for blocking the signal by which the cellular sodium-potassium pump amplifies oxidants, leading to obesity and metabolic syndrome. The study, published in Science Advances, suggests that the Na/K-ATPase might be a therapeutic target for treating these conditions.
Research shows that people with metabolic syndrome absorb less vitamin E than healthy individuals. Cow's milk, however, can promote the absorption of natural vitamin E found in foods, particularly when consumed with fat.
Researchers develop diagnostic test to assess adolescents' risk of cardiovascular disease based on metabolic syndrome severity score, which considers factors like blood pressure and cholesterol levels. The test has the potential to encourage healthy behaviors in teenagers to prevent future heart disease.
A new study found that mice lacking certain immune cells gained excess weight and developed metabolic abnormalities even on a standard diet. Removing these cells prevented weight gain and metabolic issues. The study indicates that immune cells may help control fat tissue's energy storage and reduce inflammation.
A new study discovered that bottlenose dolphins can reverse prediabetes by switching between diabetic and non-diabetic states, with the key driver being a saturated fat called heptadecanoic acid. Dolphins fed fish high in this fatty acid showed significant improvements in metabolic syndrome indicators within six months.
A four-year study of 73,357 Chinese adults found that faster heart rates were positively associated with an increased risk of developing diabetes. Participants with faster heart rates had a 23% increased risk of diabetes for every 10 beats per minute, similar to the effects of a 3 kilogram per meter square increase in body mass index.
Research highlights a disparity in cardiovascular disease risk between black and white women, particularly among those with metabolic abnormalities. Black women with two or three metabolic issues have nearly double the cardiovascular event rate as normal-weight black women without these disorders.
People with metabolic syndrome face a higher risk of cardiovascular death than those without the condition. The study found that having diabetes or high blood pressure significantly elevates this risk. Women with metabolic syndrome were also at a greater risk of death from any cause compared to their male counterparts.
A study published in JAMA Network found that nearly 35 percent of all U.S. adults and 50 percent of those 60 years or older had metabolic syndrome in 2011-2012. The condition is characterized by a combination of health conditions including obesity, high blood pressure, type 2 diabetes, and poor lipid profiles.
A recent UCLA study found that only 3.7% of US adults with pre-diabetes were prescribed metformin, despite its proven effectiveness. The study highlights the underuse of metformin for diabetes prevention, which could be attributed to lack of knowledge and reluctance by patients and doctors.
Researchers found that highly fit smokers had a 48% lower risk of metabolic syndrome compared to those in low fitness categories. Additionally, moderate fitness levels were associated with reduced risks for elevated fasting blood glucose and abnormal HDL cholesterol levels.
A new study found that night owls are more likely to develop diabetes, metabolic syndrome, and sarcopenia than early risers. Night owls tend to have poorer sleep quality and engage in unhealthy behaviors like smoking and late-night eating.
A recent analysis published in the Journal of Human Nutrition & Food Science found that dietary magnesium intake is associated with improvements in diabetes-related health outcomes. Adults who met the estimated average requirement for magnesium from food alone had significantly lower odds ratios for metabolic syndrome, obesity, and ele...
Research found that GLP-1 secretion is lower among people with pre-diabetes and obesity compared to normal weight individuals. The study suggests that early intervention with GLP-1 analogues may postpone the onset of type 2 diabetes.
Emulsifiers found in processed foods can alter the gut microbiota composition and induce intestinal inflammation, promoting the development of inflammatory bowel disease and metabolic syndrome. The study suggests that avoiding excess food consumption is crucial, as low-grade inflammation from an altered microbiota can lead to overeating.
A study of 825 women with mild gestational diabetes found that those with preeclampsia/gestational hypertension had a higher frequency of subsequent hypertension and metabolic syndrome. Women who delivered preterm and had preeclampsia/gestational hypertension were at greatest risk.
Research suggests yoga can positively impact cardio-metabolic health by reducing CVD risk factors and improving metabolic syndrome outcomes. A systematic review and meta-analysis of randomized controlled trials found significant evidence supporting the effectiveness of yoga as a therapy for these conditions.
Researchers found that weight loss surgery in obese individuals can reduce lower urinary tract symptoms, including increased frequency and urgency. The improvement is linked to improved insulin sensitivity, indicating a reduced risk of developing type 2 diabetes.
Researchers at Georgia State University and Cornell University found that promoting healthy gut microbiota can treat or prevent metabolic syndrome. The study used an improved technical approach to show that altered bacterial populations promote low-grade inflammation and metabolic syndrome.
A new study published by The Endocrine Society reveals that resveratrol increased spinal bone density in men with metabolic syndrome and improved levels of the bone formation marker BAP. This finding suggests the compound's potential as an anti-osteoporosis drug, stimulating bone-forming cells within the body.
A Mediterranean diet supplemented with extra-virgin olive oil or nuts helps reduce central obesity and blood glucose levels, reversing metabolic syndrome in 28.2% of participants. The study found no significant difference in new cases of metabolic syndrome between the two diet groups.
Researchers discover that 12-lipoxygenase (12-LO) enzyme promotes pre-diabetes and diabetes by causing oxidative stress in pancreatic cells. The study shows that a high-fat diet leads to the production of harmful molecules, ultimately damaging the cell's ability to produce insulin.
Researchers found that excess uric acid can disrupt normal metabolism, leading to the development of metabolic syndrome. A new study suggests that diet and fructose consumption may contribute to high uric acid levels, which can cause inflammation and oxidative stress in the body.
Exposure to pesticide DDT before birth is linked to increased risk of metabolic syndrome in female mice, characterized by obesity, high cholesterol, and diabetes. The study also found sex differences, with females more susceptible to these conditions.
A new study found that following a healthy lifestyle may lower childhood cancer survivors' risk of developing the metabolic syndrome. Adults who had cancer as children are at increased risk, and lifestyle habits can influence long-term health outcomes.
A St. Jude Children's Research Hospital study found that 73% of adult childhood cancer survivors doubled their risk of metabolic syndrome by failing to follow a heart-healthy lifestyle, which also increases the risk of heart disease, diabetes, and other health problems.
Researchers from UCL and the Mayo Clinic argue that labelling people with moderately high blood sugar as pre-diabetic has no health benefits. The term could create significant burdens on healthcare systems without conferring any long-term health benefits.
Researchers have discovered an enzyme that stimulates the overproduction of fatty acids and triglycerides, leading to insulin resistance and diabetes. A new drug candidate is being developed to target this enzyme, potentially treating metabolic syndrome.
Researchers used large-scale patient data analytics to predict future risk of metabolic syndrome, identifying individual variable impact on risk associated with adherence to prescribed medications and routine doctor visits. The study also found that improving waist circumference and blood glucose yielded the largest benefits.
Researchers found that patients with Barrett's esophagus and low-grade dysplasia have a high incidence rate of esophageal adenocarcinoma, while metabolic syndrome and smoking heighten concerns regarding colorectal cancer screening in men. A new guideline for endoscopy in patients with lower gastrointestinal bleeding is also introduced.
Researchers found that mice exposed to tolylfluanid developed metabolic changes similar to those of human metabolic syndrome, including increased blood sugar and body fat. The study suggests potential health risks for humans exposed to the fungicide.
Rates of prediabetes have tripled over the past decade in England, affecting over a third of adults. Those from disadvantaged backgrounds and black and minority ethnicities are disproportionately affected, with up to one in 10 progressing to diabetes annually.
Cases of diabetes and pre-diabetes in the US have nearly doubled since 1988, with obesity contributing to the surge. The burden of the disease is not evenly distributed, with higher rates among blacks, Hispanics, and the elderly.
Research suggests that patients with metabolic syndrome are more likely to experience complications after total joint replacement surgery. Obesity is a significant factor in postoperative complications, with risks increasing for those with a BMI of 30 kg/m2 or higher.
Overweight children exposed to higher levels of perfluorinated chemicals show early signs of metabolic syndrome, a cluster of risk factors for heart disease, stroke, and diabetes. The study highlights the potential public health hazard of these industrial chemicals.
A new study published in Journal of Neurotrauma found that retired professional football players who suffered repeated concussions had reduced levels of growth hormone, gonadotropin, and testosterone, leading to disorders such as metabolic syndrome and impaired quality of life. The study suggests that repeat concussion may elicit pitui...
A recent study published in Diabetologia found that metabolic risk factors cluster similarly in children and adults, increasing the risk of premature death caused by type 2 diabetes and cardiovascular diseases. Lifestyle interventions aiming at prevention should be invested in childhood to reduce the risk.
A recent study published in Gerontology highlights the long-term effects of childhood obesity on late-life health, finding that obese children may be more predisposed to complications independent of adult obesity. Early exposure to obesity can alter metabolism during a critical developmental time frame, leading to increased risk of met...