Articles tagged with Narcolepsy
This month's TLN discusses the role of genetic risk factors in sleep disorders, including narcolepsy and obstructive sleep apnoea syndrome. The study highlights the importance of investigating the effects of mobile phone use on human populations to better understand the complex mechanisms regulating sleep.
A study found narcolepsy prevalence is higher in men and peaks in the 20s, with 36% of cases lacking cataplexy. The disorder affects over 100,000 Americans, with 14 new cases developing annually in a one-million population.
Narcolepsy is a lifelong problem characterized by sudden sleep episodes and muscle paralysis triggered by strong emotions. A new study aims to understand the role of hypocretin cells in controlling sleep and arousal, with potential breakthroughs for future treatments.
A new study has found that the medication modafinil can effectively alleviate fatigue in patients with multiple sclerosis. The drug was shown to improve symptoms in 75-90% of patients, with significant benefits reported at a dosage of 200mg per day.
A brain protein linked to narcolepsy helps regulate bodily sensations and modulate sensory input from the body. Hypocretin-2 was found to inhibit activity of neurons associated with pain and temperature sensation, suggesting a potential mechanism connecting wakefulness and sensory modulation.
Researchers found a dramatic reduction in hypocretin neurons in people with narcolepsy, suggesting a potential link to neurodegenerative processes or autoimmune responses. The study suggests that replacing missing hypocretin cells may reverse symptoms of the disorder, paving the way for new treatment options.
Scientists at the University of Illinois Chicago are exploring a novel approach to measuring sleepiness using pupil size, which could revolutionize the diagnosis of sleep disorders. The study aims to establish pupillometry as an objective measure of excessive daytime sleepiness and potentially improve treatment outcomes.
Researchers discovered a connection between a brain hormone called orexin and narcolepsy, a severe sleep disorder. The study found that mice lacking the orexin gene exhibited abnormal sleep patterns and behaviors similar to those of humans with narcolepsy.
The discovery of the narcolepsy gene in dogs by Dr. Emmanuel Mignot opens the door to identification of the gene in humans and development of new treatment approaches. The study also links hypocretins, a recently discovered family of brain neuropeptides, to regulating sleep.
The Narcolepsy Network is launching a nationwide initiative to raise awareness about narcolepsy, a chronic neurological sleep disorder that affects an estimated 125,000 Americans. The 'Wake Up to Narcolepsy' program aims to educate people with the condition and their physicians about symptoms, diagnosis, and treatment options, helping ...
A study found that modafinil significantly improved the quality of life for patients with narcolepsy, reducing daytime sleepiness and increasing productivity. The medication provided sustained benefits over an extended period without debilitating side effects.
A clinical trial found that Modafinil improved wakefulness in narcoleptic patients by at least 50% compared to placebo, with fewer side effects than current treatments. The drug also showed potential as an anti-fatigue agent for truck drivers and airline pilots.