Researchers have developed a gene therapy using human blood outgrowth endothelial cells to treat hemophilia A. The treatment, which has shown long-term attainment of robust levels of factor VIII, is promising and may pave the way for testing in humans.
A VA study found that opportunistic screening for diabetes is likely more cost-effective and can be easily integrated into typical office visits. The approach takes advantage of the doctor-patient relationship, promoting better follow-up care for patients at risk of diabetes.
A study by Scott Saunders and colleagues suggests that heparan sulfate proteoglycans (HSPGs) help regulate morphogen gradients, influencing cell development and differentiation. HSPGs may also play a role in the formation of complex bone structures and organs.
Economist Robert Moffitt has received a $1.3 million MERIT award to investigate the relationship between welfare reform and out-of-wedlock childbearing, exploring potential factors beyond just welfare benefits.
The Gemini Observatory has dedicated its second telescope, Gemini South, marking a decade of work by hundreds of people to build two advanced 8-meter instruments. Astronomers in the US and around the world now have access to unprecedented sky coverage.
A University of North Carolina at Chapel Hill study found that new safety regulations adopted in 1996 contributed to a 22% decline in serious injuries at childcare centers and a 31% drop in licensed home injuries. The decline coincided with improved playground safety features and better supervision.
Professor Ramanathan recognized for his groundbreaking studies on clouds, aerosols, and greenhouse gases in the earth's climate system. His work has significantly advanced our understanding of radiative feedbacks in climate change and ocean temperature regulation.
Rockefeller University scientists have solved the three-dimensional structure of a type of chloride channel called ClC, providing new insights into its mechanism and selectivity features. The research findings are crucial for developing drugs to target ion channel impairments linked to heritable diseases such as cystic fibrosis.
A new study has found that the medication modafinil can effectively alleviate fatigue in patients with multiple sclerosis. The drug was shown to improve symptoms in 75-90% of patients, with significant benefits reported at a dosage of 200mg per day.
Researchers found that single neurons in a brain region reacted to specific features, conveying detailed information about the diagnostic features of categories. The monkeys' brains used these learned features to recognize matching faces, demonstrating how neural training sharpens perception and enables the brain to encode and interpre...
Researchers found that uncomplicated labor and vaginal delivery do not stimulate the babies' immune systems to HIV infection. Babies born to mothers with chorioamnionitis or preterm labor, however, showed activation of their white blood cells and higher risk of transmission.
Researchers have found that growth factors play a key role in regulating how embryonic nerve cells acquire the ability to process information. This study suggests possible avenues for treating damaged nerve cells and restoring their function.
The study resolves placental mammals into four major groups, revealing a common ancestor in Gondwana. Afrotheria is the oldest group, with some orders never leaving Africa, and Xenartha populations South America.