Articles tagged with Obesity
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A study published in The BMJ found that dog owners with diabetes are more likely to develop type 2 diabetes themselves than owners without a diabetic dog. However, no shared risk was found between cat owners and their pets.
A high-fat diet impairs immune cell function inside tumors, reducing their antitumor activity. Blocking metabolic rewiring in cancer cells enhances anti-tumor immunity and improves immunotherapies.
KU Leuven researchers Christine Desmedt, Tias Guns, Simon Kuhn, and Lukas Van Oudenhove have been awarded ERC Consolidator Grants. Their projects focus on breast cancer, optimisation software, reactors for sustainable chemical industry, and the impact of gut bacteria on emotions.
A new study found that individuals with longer durations of obesity are at a higher risk for cardiometabolic disease factors. The duration of obesity exposure between ages 10 and 40 years was associated with worse values for blood pressure, cholesterol, and glycated hemoglobin (blood sugar) measurements.
A study published in the journal CANCER found that Black women with early breast cancer have significantly higher obesity rates (62%) and comorbidities, such as hypertension and diabetes, than white women. Despite similar treatment decisions, these disparities contribute to a 40% mortality gap.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that gastric bypass surgery can lead to long-term diabetes remission in over half of adults with type 2 diabetes. The study suggests that weight loss is not the only factor contributing to improved blood sugar levels.
A study published in Annals of Internal Medicine found that nearly 40% of US adults with overweight and 10% with obesity do not consider themselves overweight. This lack of self-awareness is linked to lower attempts to lose weight and contributes to rising obesity rates.
A study found that lab results for adults with obesity are similar to those of their leaner counterparts, contradicting one theory behind the 'obesity paradox'. Instead, researchers suggest that unconscious bias in healthcare providers may lead to better outcomes for obese patients in critical care
A 25-year follow-up study found that obese women have an increased risk of hip fracture before age 70, especially those with below-average bone density. Women at the borderline between normal weight and overweight had the lowest risk all the way until old age.
A new study published in JAMA Network Open found that a plant-based diet increased after-meal calorie burn by 18.7% in overweight participants, leading to significant weight loss and cardiometabolic benefits. The study also showed reductions in fat mass, visceral fat volume, and liver and muscle cell lipid levels.
A new study by Queensland University of Technology found that esports players are up to 21% healthier than the general population, with many engaging in over an hour of physical exercise per day. The research also showed that top esports players were significantly more physically active and less likely to smoke or drink daily.
Researchers at the University of Illinois Urbana-Champaign found that gut hormones FGF15/19 turn off fat-producing genes in the liver. The study suggests a new target for therapeutic treatment options to address obesity-related metabolic disorders.
The European Society of Cardiology report highlights alarming trends in cardiovascular disease, including rising obesity and diabetes rates, to emphasize the need for urgent action. The report also shows that middle-income countries are struggling to meet World Health Organization targets for heart disease prevention.
A new study published in eLife suggests that Lipocalin-2, a hormone produced by bone cells, could be used to treat people with obesity. The hormone has been shown to suppress food intake and increase feelings of fullness in mice and non-human primates.
A Cleveland Clinic study shows that bariatric surgery prior to contracting COVID-19 is associated with a lower risk of hospital and ICU admission. Patients who underwent weight-loss surgery had a significantly lower rate of severe illness compared to those without a history of bariatric surgery.
A new University of Warwick-led study found that obese patients over 60 years old can lose an equivalent amount of weight as younger people through lifestyle changes alone. The research aims to correct misconceptions about the effectiveness of weight loss in older people and promote healthy ageing.
A new study warns that the current global nutrition transition will lead to an unprecedented increase in overweight and obese individuals, surpassing 4 billion by 2050. This, combined with food waste and unsustainable agricultural practices, poses significant threats to global hunger, public health, and environmental protection.
A study published in The American Journal of Clinical Nutrition found that high-protein total diet replacements led to higher energy expenditure, increased fat oxidation, and negative fat balance compared to a typical North American diet. This suggests that these diets may be a promising nutritional strategy for weight management.
A new study presents research on the effects of racket sports and exercise on knee joint degeneration in overweight individuals. The study found that racket sports accelerated degeneration, while elliptical trainer use was associated with reduced progression. High-speed lateral movements in racket sports may be driving this effect.
Researchers have identified a potential therapeutic strategy for obesity by discovering the signalling pathways responsible for the development of adipose tissue macrophages (ATMs) in obesity. ATMs play a key role in preventing lipotoxicity, where fat molecules are deposited in non-adipose tissues.
The American Heart Association's COVID-19 Cardiovascular Disease Registry found significant racial and ethnic differences in treatment and outcomes for patients hospitalized with COVID-19. Hispanic patients were more likely to have lower health insurance, while Black patients had higher rates of obesity and required more ventilator sup...
A new study from UT Southwestern finds that being overweight or obese, even in younger patients under age 50, increases the risk of severe COVID-19 complications. The study analyzed data from over 7,600 patients and found that those with severe obesity had a 36% greater risk of dying compared to normal weight individuals.
A diet high in ultra-processed fats and sugars is associated with increased inflammatory molecules, excitability of muscle nerves, and musculoskeletal neurotransmission. This study found that a six-week hypercaloric diet in mice increased neuromuscular transmission, leading to muscle pain.
Researchers found that female mice exposed to cadmium during pregnancy became obese and developed fatty livers, while male offspring were not affected. The study suggests that cadmium exposure may act as a sex-specific delayed obesogen, disrupting liver function and glucose processing.
A new study published in the American Journal of Transplantation shows that simultaneous robotic-assisted kidney transplant and weight loss surgery is safe for obese patients. The procedure resulted in a significant reduction in surgical complications and improved cardiac function, with all patients experiencing a substantial weight loss.
Researchers will investigate the role of Cyp2b genes, human CYP2B6 gene, and environmental toxicants like PFOS in obesity and fatty liver disease. The study aims to understand complex interactions between diet, fat stores, and genetic factors.
Researchers at the National Institutes of Health (NIH) have discovered a gene called Prkar2a in mice that influences their eating habits and motivation to exercise. The study found that mice lacking this gene consumed less high-fat food and drank less sugar solution than those with the gene, while also being more inclined to exercise.
Mice fed a Western diet showed faster decline in odor detection and learning abilities compared to controls. The researchers suggest high dietary sugar content, rather than obesity or hyperglycemia, may be linked to this deterioration.
The Obesity Society recognizes Roxane Gay for her powerful writing on obesity challenges, Ted Kyle for his influential newsletter ConscienHealth, and Rudolph Leibel for his groundbreaking discoveries on leptin and body weight regulation. These awardees have significantly contributed to understanding obesity.
Researchers found that weight-reduction surgery significantly reduces the risk of a second heart attack, cardiovascular event, and death among severely obese patients with a prior heart attack. Patients who underwent surgery also experienced improvements in sleep apnea, hypertension, cholesterol, and Type 2 diabetes.
A nationwide cohort study found that severely obese individuals who underwent gastric bypass or sleeve procedure had a lower risk of additional myocardial infarctions and improved survival rates. The study suggests that metabolic surgery may have a positive impact on cardiometabolic risk factors beyond weight loss.
A global survey during the COVID-19 lockdown found that people with obesity improved their diets but experienced sharp declines in mental health and high incidence of weight gain. The study emphasizes the importance of monitoring mental health screenings and remote visits to prevent irreversible health effects.
A new study has found that non-obese Vietnamese Americans are 60% more likely to have diabetes than non-obese, non-Hispanic White Americans. Only 9% of Vietnamese Americans with diabetes were obese, compared to half of all non-Hispanic White Americans.
The 38th Annual Meeting of The Obesity Society will present innovative scientific research results through oral and poster abstracts. These communications highlight new anti-obesity medication clinical trials and comparisons of weight loss diets.
A University of Gothenburg study finds that individuals who undergo obesity (bariatric) surgery have a higher average life expectancy compared to those given conventional treatment for obesity. The study, published in The New England Journal of Medicine, shows that bariatric surgery prolongs life expectancy by 3 years, but patients sti...
A systematic review of nine clinical studies involving 6,577 patients with COVID-19 found that obesity significantly increases the risk of severe illness and death. The study also highlights the importance of addressing obesity through public health policies to prevent COVID-19-related complications.
A new study by Mount Sinai researchers found that a person's risk of uncontrolled chronic disease increases after moving to a place where the condition is more common. The study analyzed millions of adults who moved to new neighborhoods, counties, and states, tracing how their health changed after the move.
Higher HMGB1 levels associated with obesity, inflammation and cardiovascular disease in younger adults, particularly females and blacks. The study found a link between circulating HMGB1 levels and increased blood pressure, stiffer arteries and inflammation.
Controlling blood sugar levels boosts cognitive function, including thinking, learning, and remembering. However, more weight loss and exercise only improve executive function skills, while verbal learning and memory decline. Effective management of type 2 diabetes is crucial to offset its negative effects on brain health.
The Obesity Society has announced four honorees for its annual symposium, which will present the latest insights into preventing and treating obesity. The honorees represent a range of topics, including the effects of obesogenic medication on weight change outcomes.
A study published in The Lancet Public Health found that modifiable health risks, such as obesity and high blood pressure, account for 27% of US personal health care expenses. These costs are largely driven by five risk factors: overweight and obesity, high blood pressure, high blood sugar, poor diet, and smoking.
A study from the University of Queensland found that a gene controlling inflammation increases the risk of obesity. Researchers discovered that variations in this gene lead to excessive inflammation in fat tissue, contributing to weight gain. By turning off the gene in mice, they were able to prevent weight gain and reduce diabetes risk
A case series report found that prone positioning can help normalize electrocardiogram (ECG) readings in patients with COVID-19. The study presented a woman with comorbidities and shortness of breath, whose ECG improved after being placed in the prone position.
A randomized clinical trial found that restricting daily eating to between 12 pm and 8 pm resulted in significant weight loss among participants. The study also showed improvements in metabolic markers, suggesting a potential therapeutic strategy for obesity.
A recent study highlights the prevalence of malnutrition among overweight or obese individuals, which can lead to serious health conditions. Physicians are urging clinicians to recognize the importance of nutritional screening and counseling in patients with increased body mass index.
A world-first study has found that severely overweight individuals are less likely to re-wire their brains and form new neural pathways. This impairment in brain plasticity makes it harder for them to learn new tasks and remember things, with significant implications for people recovering from strokes or brain injuries. Obesity is asso...
A new study found that high-intensity interval training (HIIT) combining cycling and rowing improves insulin sensitivity and reduces blood sugar levels in individuals with obesity and type 2 diabetes. The study also showed improvements in body composition, including a reduction in fat mass and an increase in muscle mass.
Cats that eat one meal a day are more satisfied, with higher post-meal levels of appetite-regulating hormones. This feeding schedule also promotes lean body mass by increasing blood amino acids.
A study by Cleveland Clinic found that surgically induced weight loss of 5-10% improves life expectancy and cardiovascular health. The research suggests metabolic surgery may contribute to health benefits independent of weight loss.
A recent study published in The BMJ found that excess belly fat is associated with a higher risk of early death from any cause. In contrast, larger hips and thighs were linked to a lower risk of premature mortality. This suggests that measuring central fatness may be a more reliable indicator of risk than body mass index.
A multi-site study found that using prophylactic negative pressure wound therapy (NPWT) does not significantly lower the risk of infection for women with obesity who have undergone cesarean delivery. The study, which included over 1,600 participants, also found increased rates of skin irritations in the NPWT group.
A new study reveals that nearly 20% of US adults face food insecurity, with worse rates among Hispanics, Blacks, people with obesity, and women. The report also links food insecurity to obesity and other health issues, highlighting the need for public policy solutions.
A study of over 1,600 obese women found no significant difference in infection rates between those treated with NPWT and standard wound dressing. Despite this, women in the negative pressure group experienced more skin irritations.
Researchers at CNIC have discovered a mechanism explaining how macrophages regulate obesity and related diseases like fatty liver disease and type 2 diabetes. The study shows that oxidative stress leads to mitochondrial metabolism changes in macrophages, fostering inflammation and obesity.
A new study found that a Mediterranean-like diet partially modified the association between obesity and cardiovascular mortality. Higher body mass was associated with increased risk of death from cardiovascular disease, but adherence to healthy diets like Mediterranean-style eating reduced this risk.
Research suggests that conditions related to obesity, such as inflammation and leaky gut, leave lungs more susceptible to COVID-19. Additionally, high levels of ACE2 receptors in obese individuals can lead to a higher viral load, exacerbating disease severity.
A study of 26,000 heart transplants found that patients receiving hearts from severely obese donors had similar short-term and long-term outcomes as those receiving hearts from non-obese donors. The research has the potential to expand the critically low donor pool by increasing the number of obese donors.
A new study published in PLOS Medicine found that metabolic surgery reduces the risk of major adverse cardiovascular events and death for individuals with hypertension and a BMI over 35kg/m2. The surgery was shown to be effective in treating hypertension, suggesting it as an option for patients with obesity and high blood pressure.
The article reviews mechanisms linking obesity and diabetes to COVID-19 severity, suggesting that bacterial conditions work with the virus to increase disease severity. A combined deficiency in ACE2 caused by COVID-19 leads to impaired gut barrier function, allowing bacteria and toxins to leak into the circulation.
Researchers found that the typically 'bad' APOE ε4 variant can also protect against obesity and type 2 diabetes, while the 'good' ε2 variant increases risk of certain conditions. The study's findings provide valuable insights into how the APOE gene impacts health and disease.