Articles tagged with Pain
A phase III clinical trial suggests that suramin offers substantial pain reduction and moderate delay in disease progression for patients with advanced prostate cancer. The study involved 458 patients, who experienced significant pain reduction and a longer period of time compared to those receiving only hydrocortisone and a placebo.
Researchers at the University of Pennsylvania School of Medicine found that delivering pain medication to patients before surgery reduces post-operative pain long after. The study, which involved 90 men undergoing radical prostatectomies, showed significant pain reduction in patients who received preemptive analgesia.
A new study by Ohio University researchers found that women with osteoarthritis or rheumatoid arthritis use various coping mechanisms to deal with pain, including relaxation and emotional support. Women were better at regulating the emotional aspect of pain, while men struggled more with mood changes after high-pain days.
Researchers have made significant progress in understanding the effects of gender, age, hormones, and other factors on heart disease. A promising new diagnostic tool, dobutamine stress echocardiography, is being tested for its accuracy in detecting coronary artery dysfunction in women.
A UCSF research team has made a striking discovery that mild and intense pain are biologically distinct, involving different neurotransmitters. This knowledge could lead to the development of new drugs targeting these molecules to provide effective pain relief with lower morphine doses.
A new clinical approach combining echocardiograms with troponin T levels significantly increases diagnostic accuracy for chest pain, predicting hospital admissions and cardiac events. This method has the potential to reduce unnecessary hospitalizations and improve patient outcomes.
A new laser-based procedure called transmyocardial revascularization (TMR) has been shown to improve symptoms of severe chest pain in patients with heart disease. After three months, 86% of TMR patients experienced improvement, while only 12% of those treated with medication alone saw results.
Researchers at Oregon Health & Science University found that adenosine triphosphate (ATP) stimulates pain-sensing nerves by binding to a receptor called P2X3 on nerve cell membranes. This discovery may pave the way for the design of new pain-relieving drugs.
Studies at Yale and the National Cancer Institute have shown capsaicin's pain-relieving effectiveness. Capsaicin stimulates nerve cells to release more Substance P, leading to decreased pain signals and improved mobility.
Researchers found that people at high risk of developing hypertension have a decreased pain sensitivity, which may be due to an overactive brain center. This could lead to the suppression of pain signals and potentially affect blood pressure control.
A study led by Johns Hopkins researchers found that positive messages nearly doubled the pain threshold and tolerance of both groups, while negative messages lowered it. The results suggest that addressing both biological and emotional causes is crucial for pain treatment.
The implant is a button-sized polymer that releases hydromorphone over one to three months, providing steady pain medication. It could be used in developing nations where cancer rates are high but limited treatment options exist, and potentially as an alternative to oral methadone treatment for heroin addicts.