Articles tagged with Cancer Patients
Haizhen Wang, a MUSC Hollings Cancer Center researcher, has received a $225,000 Young Investigator grant from the Melanoma Research Alliance. She will investigate the function of protein CDK6 in T-cells to improve melanoma therapy outcomes.
A new study found that delaying lung cancer surgery for more than 12 weeks after diagnosis is associated with a higher risk of recurrence and death. Patients who underwent surgery within this time frame lived 7.5 months longer than those who delayed treatment.
Even among insured individuals, up to 10% of cancer survivors delayed follow-up care due to financial constraints. Financial stress and anxiety hinder timely survivorship care, particularly among vulnerable populations such as racial minorities, women, and those with lower incomes.
A new Penn Medicine study shows that blood cancer patients with lower antibody levels can rely on T cells to combat COVID-19. The research found that patients with higher CD8 T cell counts were more than three times likelier to survive than those with lower counts.
A new imaging technique using fluorothymidine (FLT) is being tested to predict the success of bone marrow transplants. The trial aims to reduce waiting time for patients and improve survival rates, currently 30% over three years after failure.
The National Foundation for Cancer Research has announced the winners of its 2021 Salisbury Award Competition, recognizing promising cancer research innovations. The first prize winner is TanoMed's technology training host immunity against a specific member of the carcinoembryonic antigen-related cell adhesion molecule family, CEACAM5.
Researchers developed an AI system to guide oncologists in treating head and neck cancer patients, considering treatment efficacy and potential future decisions. The system analyzes real patient data to provide personalized recommendations and maximize survival outcomes while minimizing chemotherapy and radiation side effects.
New research suggests that anti-cancer therapies can hasten cellular aging, leading to increased inflammation and fatigue in patients with head and neck cancer. Epigenetic changes associated with these treatments may contribute to age-related conditions.
The USC Norris Comprehensive Cancer Center has formed partnerships with the Lazarex Cancer Foundation to create Cancer Wellness HUBs in Los Angeles, addressing health disparities through community engagement and education. The initiative aims to provide vital resources and support services for cancer patients and their families.
A dental school researcher has received FDA approval to begin clinical trials for a new cancer therapy using a protein found in an oral bacterium. The treatment, Leukothera, rapidly kills cancer cells without compromising the immune system, offering a potential alternative to existing treatments.
The University of Pennsylvania School of Medicine has doubled the percentage of Black participants in cancer clinical trials through community outreach and engagement efforts. The initiative improved access and treatment for historically underrepresented groups, with significant increases observed in non-therapeutic interventional and ...
The GEM ExTra test uses whole exome sequencing and RNA sequencing to detect actionable mutations in patients with advanced solid tumors. It has been validated through clinical utilization and provides clinically actionable information to guide patient management decisions.
In a Phase I trial, IACS-6274 demonstrated successful target inhibition and early signs of anti-tumor activity in 60% of evaluable patients. Durable disease stabilization was observed in six patients with biomarker-defined advanced cancers.
A new study published in the Journal of Clinical Oncology reports findings on Huntsman at Home, a cancer hospital-at-home model that demonstrates lower costs and better outcomes for patients. The study found that participants had 55% fewer hospitalizations and 47% lower healthcare costs compared to those who did not participate.
A lack of insurance leads to worse cancer survival across the 16 most common cancers, with uninsured patients 60-64 facing significantly poorer outcomes than their older counterparts. This disparity is driven by the high costs of newer potentially lifesaving treatments, which can be unaffordable for those without insurance.
A study published in the European Journal of Preventive Cardiology found that nearly one in four heart failure patients experience depression or anxiety, compared to 23% of breast cancer patients, 22% of prostate cancer patients, and 15% of digestive organ cancer patients. Heart failure patients are also at a higher risk of developing ...
A study by Kaiser Permanente found that insured patients with cancer had better survival rates, especially among Black and Latino patients. The researchers analyzed data from the California Cancer Registry and found lower mortality rates among Kaiser Permanente members in Southern California.
A new study examines the safety of COVID-19 vaccines in patients with cancer, providing insights into potential risks and benefits. The research found that while some cancer treatments may interact with COVID-19 vaccines, the overall risk is low.
Researchers at Huntsman Cancer Institute discovered that nicotinamide phosphoribosyltransferase (NAMPT) plays a key role in how immune cells fight melanoma tumors. The study found that disrupting the NAMPT pathway impairs antitumor function, and novel therapies targeting this pathway may lead to improved outcomes for patients.
A phase II study by Penn Medicine shows rucaparib helped control cancer growth in patients with BRCA or PALB2 genetic mutations. The results support the use of rucaparib as a maintenance therapy for pancreatic cancer patients, offering a safe and effective alternative to chemotherapy.
A new study found that individuals experiencing pre-loss grief symptoms can adjust, but certain factors such as gender and caregiving burden exacerbate the experience. The research documented a significant correlation between dementia patients' family members and severe pre-loss grief.
A new UCSF study reports that cancer patients experience a deep sense of loneliness during the COVID-19 pandemic, with 53% of participants classified as lonely. The study also found higher levels of depression, fatigue, and sleep disturbance among lonely patients.
Researchers screened over 60,000 blood samples from asymptomatic individuals for IgG antibody to the viral spike protein, finding strong correlations between high anti-S IgG levels and neutralizing activity. The study also showed age-related differences in antibody responses and a higher prevalence of COVID-19 among African Americans.
Researchers developed an AI system, TOAD, that accurately predicts the origin of tumors in cancer cases with unknown primary sites. The model, trained on gigapixel pathology images, correctly identified cancer types and listed diagnoses as top predictions 96% of the time.
A new study aims to evaluate the effectiveness of an automated, smartphone-based approach to incentivizing smoking cessation among low-income adults in Oklahoma. The 5-year project will enroll 532 participants and assess the impact of monetary incentives on smoking abstinence.
A computational method using machine learning and feature sets derived from molecular simulation can predict the functional consequences of genetic variation in cancer drugs. This technology has the potential to accurately diagnose cancer variants and improve treatment outcomes by tailoring therapy to individual genetic profiles.
A study at ESMO Breast Cancer 2021 Virtual Congress reveals breast cancer survivors experience varying levels of symptoms after treatment, with some requiring active symptom management. Patients with comorbidities, such as heart disease and diabetes, are more likely to experience a high symptom burden.
A team of researchers, including Saket Navlakha and Dr. Sejal Morjaria, developed a computational tool to predict COVID-19 severity in cancer patients. The tool has an accuracy rate of 70-85% and prevents unnecessary expensive testing, improving patient care.
New research reveals patients with multiple comorbidities are more likely to be screened for colorectal cancer than those without any health conditions. Regular screenings significantly reduce cancer mortality.
A new set of guidelines developed by AATS and ESTS recommends a 30-day course of Venous Thromboembolism (VTE) prophylaxis post-discharge for patients undergoing surgical resection for lung or esophagus cancer. The guideline panel endorsed by American Society of Hematology and International Society on Thrombosis and Haemostasis found th...
A new test, called Guardant Reveal, can detect residual cancer DNA in the blood of patients after treatment without knowing the specific mutations present in their tumor. The study found that this approach was similar in sensitivity and specificity to traditional methods.
Breast cancer patients experience frequent job changes after diagnosis, with around ten percent reporting involuntary changes. The study suggests that a supportive work environment and understanding from managers can facilitate a satisfactory return to work.
A new study from the University of Missouri School of Medicine found that people of color, those with a higher income, and younger individuals are more likely to participate in cancer clinical trials. The analysis of 20,053 respondents showed an average overall clinical trial participation rate of 6.51%, with significant differences in...
A recent study found that only 16% of male teenagers received the HPV vaccine, highlighting a significant gap in vaccination rates. The vaccine is essential for preventing oropharyngeal cancer, which affects 80% of male patients diagnosed with this condition.
A recent study by the University of Eastern Finland found that middle-aged men who experience loneliness are at an increased risk of developing cancer. The study, which followed 2,570 men over time, found that loneliness was associated with a 10% higher risk of cancer.
A multi-institutional team of researchers has identified genetic abnormalities that drive pre-cancer cells into becoming invasive head and neck cancer. The study found that patients with specific genetic imbalances are less likely to respond to immunotherapy.
The NCI-MATCH cancer clinical trial is expanding with the addition of a new treatment arm, Arm Z1M, which targets mismatch repair deficiency and LAG-3 protein expression. This brings the total number of available treatment arms to 12, addressing 12 unique molecular targets and corresponding drugs that have shown efficacy evidence.
The UK Markey Cancer Center has launched a clinical trial to evaluate the anti-cancer activity of ArtemiLife coffee products in preventing ovarian cancer recurrence. Participants will drink coffee up to four times daily for five months after completing treatment, aiming to delay or eliminate cancer return.
Researchers at Ohio State University Comprehensive Cancer Center identified distinct mutational and molecular changes in four SCLC subtypes, providing new insights into treatment resistance. The findings suggest that subtyping patients before systemic therapy could play a role in drug development and therapy selection.
A new algorithm, MMRDetect, identifies tumours with mismatch repair deficiencies that can be targeted by immunotherapies. The algorithm uses mutational signatures from genome sequencing data to personalize cancer treatments.
Dr. David Lyden, a Weill Cornell Medicine physician-scientist, has been inducted into the Association of American Physicians for his pioneering work on cancer metastasis and spread. His research reveals that tumors produce factors that prime distant organs to become hospitable sites for cancer growth.
A UT Southwestern Medical Center review of Texas Cancer Registry data found that Black and Hispanic patients under 40 with cancer have lower survival rates compared to their white counterparts. The study also showed that poverty and lack of insurance coverage exacerbate these disparities.
The UVA Center for Engineering in Medicine has developed a robust process to help researchers win funding from institutions like the National Institutes of Health. The center's first seed grant cohorts have achieved astonishing results, including $12 million in follow-on funding with just a $2 million initial investment.
Researchers developed a test using artificial intelligence to measure proteins in advanced bowel cancer patients, predicting treatment benefits. The technique could help doctors and patients decide on the best treatment options, targeting those with higher protein levels.
A new analysis published in Psycho-Oncology found that fear of cancer recurrence leads to increased use of healthcare resources by cancer survivors. Implementing existing effective interventions for fear of cancer recurrence may improve both mental health and reduce unnecessary healthcare usage.
A new Penn State study has found that higher mushroom consumption is associated with a lower risk of cancer. The systematic review and meta-analysis analyzed data from over 19,500 cancer patients and found individuals who ate 18 grams of mushrooms daily had a 45% lower risk of cancer compared to non-mushroom eaters.
A Mayo Clinic study found that 15.5% of patients with colorectal cancer had inherited gene mutations, which can be detected through universal testing and broader gene panels. This discovery has the potential to lead to targeted cancer therapies and earlier disease detection in families.
The Herringbone Microfluidic Probe (HB-MFP) effectively isolates Circulating Tumor Cells from blood samples, providing insights into cancer metastasis. Researchers believe this technology has great promise for diagnosing and prognosticating prostate cancer using liquid biopsies.
City of Hope's Betty Ferrell is honored with the 2021 ONS Lifetime Achievement Award for her decades-long dedication to improving pain management and quality of life for cancer patients. With over $70 million in grant funding, she has trained millions of nurses and clinicians globally on palliative care.
A study published in JAMA Network Open found that treating older patients with early-stage breast cancer did not improve survival rates and may cause harm. Researchers analyzed data from over 3,000 women aged 70 and found that omitting treatments like sentinel lymph node biopsy and radiotherapy did not affect recurrence or survival rates.
The NCCN Foundation has awarded $150,000 in funding to six young investigators advancing research on cancer prevention, racial disparities in screening, and CAR T-cell therapy. The recipients will present their research at the NCCN 2023 Annual Conference.
Researchers have identified specific super-enhancers that stimulate the activity of critical cancer genes in triple-negative breast cancer (TNBC). The study reveals that deleting certain super-enhancers can reduce tumour cell growth and improves survival chances. Dr Rebecca Chin and Dr Wang Xin's findings may lead to the development of...
A new registry study linked non-alcoholic fatty liver (NAFLD) to a 17-fold increased risk of liver cancer, particularly hepatocellular carcinoma. NAFLD patients were also found to have a higher risk of other cancers, emphasizing the need for targeted interventions and personalized screening strategies.
A study of over 1000 patients found UK cancer patients were 1.5 times more likely to die after a COVID-19 diagnosis compared to European counterparts. This increased mortality rate may be attributed to the UK's lagging cancer care and patient frailty.
Researchers at Yale Cancer Center have advanced a tumor-targeting and cell penetrating antibody that can deliver payloads to stimulate an immune response against melanoma. The study achieved almost complete tumor suppression in mice with melanoma tumors following intravenous injection of antibody/RNA complexes.
Researchers at Yale Cancer Center discovered that acquired resistance to immune checkpoint inhibitors is linked to reduced MHC-II molecule expression and increased tumor hypoxia. Combining immune checkpoint inhibitors with anti-hypoxia agents can slow the development of resistance.
A recent study by Yale Cancer Center reveals that young patients with early-onset colorectal cancer (under age 50) have a better survival rate than those diagnosed at older ages. After adjusting for stage at diagnosis, these patients had a 5% lower risk of death compared to those diagnosed between 51-55 years old.
Researchers from MD Anderson Cancer Center present promising results on RET fusion-positive cancers, HGG, LGG, and ovarian cancer. The FDA-approved selpercatinib shows clinical benefits in preventing or inhibiting tumor growth beyond lung and thyroid cancers.
A personalized cancer vaccine developed using a computational platform raised no safety concerns and showed potential benefit in patients with high-risk cancer recurrences. The vaccine was well-tolerated, with minor injection-site reactions, and demonstrated early potential benefits after administration.
A study published in Clinical Cancer Research found that specific gene signatures and immune cells can predict response to immunotherapy in bladder cancer patients. The researchers identified potential biomarkers for treatment resistance and new combination therapeutic approaches to overcome such resistance.