Articles tagged with Cancer Patients
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A nationwide study in England has collected data on 30-day mortality for patients with breast and lung cancer treated with chemotherapy, identifying factors such as age, general well-being, and NHS trusts with higher-than-expected rates of mortality. The study aims to improve patient care and inform clinical decision-making.
Researchers at Houston Methodist developed an AI software that reliably interprets mammograms to predict breast cancer risk. The software achieves 99% accuracy in 30 times human speed, reducing unnecessary biopsies and saving physician hours.
The European Society of Cardiology has launched a position paper to tackle the cardiac toxicity of anticancer therapies. The document reviews nine categories of cardiovascular complications and provides recommendations for detection, prevention, and treatment.
A new study reveals how a cell surface molecule controls T-cell entry into the thymus, offering hope for immunotherapeutic targeting in cancer patients. The research found that stimulating Lymphotoxin beta receptor can enhance initial thymus recovery and boost transplant-derived T-cells.
Researchers at Arizona State University developed a new method to predict which BE patients are at risk of developing cancer. The study highlights the power of studying genetic diversity as a reliable predictor of cancer development and spread.
A new study reveals that socioeconomic differences between white and ethnic minority patients are the main factor affecting their chances of survival. Patients with higher income, insurance status, and marital status tend to have better outcomes.
A new study by Queen Mary University of London found that certain Barrett's Oesophagus cells can be identified as 'born to be benign' or 'bad', allowing for early detection and prevention of oesophageal cancer. The test uses genetic analysis of individual cells, predicting future risk regardless of time since abnormal cell appearance.
A study found that parents are more likely to support laws requiring HPV vaccination for school entry if their state offers opt-out provisions. However, the study's lead author warned that such opt-out provisions may weaken the vaccine requirements' effectiveness.
Patients who initially screened negative for lung cancer but developed the disease one to two years later had more aggressive disease, according to a new study by researchers at Moffitt Cancer Center. The study highlights the importance of continued lung cancer screening in high-risk patients.
A new study suggests that genomic sequencing research may be missing key mutations in different racial and ethnic groups due to a lack of tumor samples from minorities. This could lead to unequal treatment opportunities and worsen disparities in cancer care.
A systematic review found that music interventions significantly reduce cancer patients' anxiety, pain, and fatigue, while improving their quality of life. Music therapy led to a moderate increase in quality of life, while music medicine had less impact.
A new study assesses the effectiveness of self-guided online genetic education in reducing anxiety and stress among cancer patients undergoing tumor gene testing. Researchers hope to improve patients' experience with precision medicine by increasing knowledge about test limitations and benefits.
Researchers at Stanford Medicine developed a machine-learning approach that accurately differentiates between two types of lung cancers and predicts patient survival times better than human pathologists. The method assesses critical disease-related features, including cell size, shape, and texture, to improve patient outcomes.
The new guideline establishes a two millimeter margin as the standard for adequate margins in DCIS treated with whole breast radiation therapy, potentially reducing re-excision rates and improving cosmetic outcomes. This recommendation is supported by evidence and aims to improve quality of care and patient outcomes.
Patients with relapsed or resistant AML experienced responses to venetoclax, a selective BCL-2 inhibitor, with complete remissions in some. The study's results support the mechanism of action of venetoclax and offer potential as a predictive biomarker for BH3 mimetics.
Researchers developed an algorithm called JAMMIT that uses advanced mathematics to identify patterns across multiple molecular data types. The algorithm can accurately predict which patients would benefit most from chemotherapy and combining it with immunotherapy, leading to improved clinical outcomes and reduced costs.
A new study published in Cancer found that uninsured and Medicaid-covered men with testicular cancer had a higher risk of death from the disease compared to insured patients. The researchers analyzed outcomes and insurance status for 10,211 men diagnosed with testicular cancer between 2007 and 2011.
Two new studies found that uninsured or Medicaid-covered cancer patients experience delayed diagnoses, less optimal treatment, and shorter survival times compared to those with other forms of insurance. The research highlights significant disparities in cancer care across different insurance statuses.
A new study has identified gene expression profiles in renal cell carcinoma patients that are less likely to respond to the immunotherapy nivolumab. The study found that tumors with higher levels of metabolism-related genes were more likely to resist treatment and did not benefit from nivolumab, which targets PD-L1 protein.
Researchers found that over half of patients with a rare form of sarcoma had genetic errors in genes known to increase cancer risk, such as p53 and BRCA1. This study provides new clues to the phenomenon of 'cancer families' and suggests that multiple genetic mutations working together may contribute to inherited cancer predisposition.
Researchers have found a way to detect ovarian cancer early using a protein test, providing new hope for patients. An enzyme called SIK2 has been identified as key in making ovarian cancer more deadly, offering a potential new treatment target.
A retrospective clinical study found that patients with melanoma who received both ipilimumab and local peripheral treatments had significantly prolonged overall survival compared to those who received only ipilimumab. The median overall survival for these patients was 93 weeks, compared to 42 weeks for those receiving only ipilimumab.
A new study found delirium to be relatively frequent and underdiagnosed among advanced cancer patients visiting the emergency department, regardless of age. The study highlights the need for better assessment and monitoring of delirium in this population.
A study by Rice University and MD Anderson Cancer Center found significant differences in adherence to recommended cancer treatment for elderly patients across 22 Texas hospital referral regions. Regional variations in treatment rates persist despite the presence of treatment specialists and teaching hospitals.
The review highlights the effectiveness of WHO cancer pain relief guidelines in promoting cancer pain relief. The guidelines have been widely adopted despite initial release in 1986, making them a valuable resource for healthcare providers.
A phase II clinical study found that treating metastatic thyroid cancer patients with the BRAF mutation showed promising anti-tumor activity in a third of patients, with an overall response rate of 38%. The therapy vemurafenib joins other effective treatments for this patient population.
Sorafenib treatment reduces immune-suppressive phenotypes in HCC patients, including decreased PD-1 expression and lower regulatory T cells. These responses correlate with increased overall survival.
A new study found that while more imaging after thyroid cancer treatment identifies recurrence, it does not always lead to improved survival. Radioiodine scans, however, were associated with better outcomes.
A high dietary intake of omega 3 fatty acids from oily fish may help lower the risk of death from bowel cancer in patients diagnosed with the disease. Patients with a higher omega 3 intake were found to have a 41% lower risk of dying from their disease, according to researchers.
Cancer Research UK has tripled its investment in pancreatic cancer research, aiming to improve diagnosis and treatment. The charity hopes to develop better treatments and improve survival rates for patients affected by the disease.
Researchers discovered a correlation between rare POLE mutations in bowel cancers and improved patient outcomes. These tumours are less likely to recur, particularly when diagnosed at an early stage.
Researchers found daily meetings between physicians and intensivists, care protocols, and pharmacist presence are associated with increased survival rates among cancer patients in ICUs. These simple processes can reduce mortality by up to 70% and promote cost reduction.
A study at the University of Texas MD Anderson Cancer Center found that genetic mutations in DNA mismatch repair deficiency (dMMR) are present in 15% of colorectal cancer cases. The study identified MSH2 and MSH6 as the most commonly affected genes, providing a new approach to diagnosis and treatment using precision medicine.
The GW Cancer Center will train patients and healthcare providers on how to improve communications for better health, with a focus on patient health literacy and cultural sensitivity. The project aims to examine the impact of various factors such as gender, race, and income on the patient-provider relationship.
Researchers have found an association between adjuvant chemotherapy and improved survival in stage 2 colon cancer patients, contradicting current clinical guidelines. The study analyzed 153,110 patients with stage 2 colon cancer and found that those who received adjuvant chemotherapy survived longer than those who did not.
The Damon Runyon Cancer Research Foundation has awarded over $4 million to 10 top clinical investigators to support patient-oriented cancer research. The award aims to address the shortage of physicians capable of translating scientific discovery into new breakthroughs for cancer patients.
A study found that nearly all cancer patients overestimate their chances of survival compared to their doctors' estimates. The researchers emphasize the importance of accurate communication between physicians and patients in making informed treatment decisions.
A new study finds that most patients with advanced cancer report optimistic survival expectations despite clinicians' more conservative estimates. Patients from diverse backgrounds also show disparities in understanding their oncologists' opinions.
A national initiative prioritized research on venous thrombosis (VTE) in cancer patients, citing a 20% prevalence rate and increased risk with chemotherapy. The study identified key areas for future research, including platelet contributions to VTE and the impact of cancer therapies on blood cells.
A new study found that patients who develop heart failure after their first heart attack are at a higher risk of developing cancer. After an average of 4.9 years of follow-up, 21% of these patients were diagnosed with cancer, compared to 8.2% of those without heart failure.
The Moffitt Cancer Center is conducting a nationwide study on e-cigarette use, tracking 2,500 adult smokers who use both cigarettes and e-cigarettes. The study aims to understand the long-term impact of e-cigarettes on traditional cigarette use.
A new study found that individuals with diabetes may have a higher risk of developing cancer before and immediately after a diabetes diagnosis. The study suggests that type 2 diabetes may increase the risk of several types of cancer, particularly shortly after diagnosis.
Researchers at H. Lee Moffitt Cancer Center discovered a novel way to control SETDB1 protein activity through monoubiquitination, which inhibits target gene expression and could lead to new cancer therapeutics. This breakthrough suggests E2 enzymes as attractive targets for cancer treatment.
A diagnosis of high cholesterol is associated with reduced mortality and improved survival in four common cancers: lung, breast, prostate, and bowel cancer. Statins are linked to lower risk of death, with significant reductions seen in all four types of cancer.
A recent study has discovered a strong link between genetic mutations and sensitivity to specific drugs in patient-derived cancer cell lines. The researchers found that these cell lines harbor most of the same genetic changes found in patients' tumors, making them useful models for identifying effective treatments.
A study led by Boston Children's Hospital researchers finds that the loss of let-7 microRNA family is central to neuroblastoma development. The study suggests strategies focused on restoring let-7 could provide a fresh, low-toxicity approach to treating this childhood cancer.
A genetic test that spots cancer-related DNA in blood can accurately predict colon cancer recurrence, according to a study of Australian patients. The 'liquid biopsy' detected DNA fragments in the blood of 20 patients with early-stage colon cancer, 11 of whom developed recurrences.
A phase II study evaluates the safety of palbociclib in African American patients, including those with benign ethnic neutropenia. The study aims to determine if these patients can safely use the drug, which was previously excluded due to risk of infection.
The research team will explore the biological and genetic underpinnings of breast cancer in African-American women, with a focus on identifying novel genes and gene pathways. The study aims to improve knowledge of breast cancer biology, particularly for this population.
A genetic test detecting tumor DNA in blood accurately predicts colon cancer recurrence in some patients. The test could help clinicians decide which patients need additional treatment after surgery, improving diagnostic approaches and potentially increasing survival rates.
A new study reveals that Argentine tango practice can significantly improve balance and reduce falls risk among cancer patients experiencing peripheral neuropathy. The dance intervention course reduced standing postural sway by 56% in just five weeks, providing a promising balance intervention for cancer survivors.
Researchers identified genetic mutations in immune system genes that may lead to synchronous colorectal cancer, a rare type of bowel tumor. The study found that these patients have inherited damaging mutations that can cause an inflammatory environment in the gut, increasing the frequency of independent cancer-initiating events.
The article introduces a new 'game plan' for oncologists to incorporate new therapies and approaches into clinical guidelines quickly. CancerLinQ, a web-based rapid-learning system, will provide point-of-care clinical decision support with the latest evidence-based recommendations.
MABp1 improves symptoms, reduces inflammation and increases clinical response rate by 76%, with a 3x longer survival time for responders. Excellent safety and tolerability were also observed.
The study projects that by 2040, there will be 26.1 million cancer survivors in the US, with 73% aged 65 or older. Increasing age increases the chance of comorbid conditions, and gaps exist between men and women in older age groups.
A phase III trial found that chemoradiotherapy after surgery for gastric cancer (GC) does not achieve better outcomes than post-operative chemotherapy. The study, which involved 788 patients, showed equivalent five-year survival rates of 40.8% in both treatment arms.
A new study reveals that only 8% of patients with large, apparently benign polyps have cancer, suggesting advanced endoscopic treatments like EMR and ESD as viable options. This finding could improve patient outcomes, reduce complications, and lower healthcare costs.
Researchers developed a novel method to identify likely cancer drivers among hundreds of genomic alterations. The technique uses tumor gene alterations to report on cancer progression, pinpointing GON4L as a potential driver and therapeutic target.
A Rice University lab developed a predictive model to treat leukemia patients, using a unique set of patient data. The top-performing models were able to predict patient response to therapy with an accuracy of close to 80 percent.
A study found that adults with acute leukemia had a significantly higher risk of death if they lived in certain North Carolina regions with limited healthcare resources. Researchers analyzed data from 2003 to 2009 and found that patients in these areas were more likely to die, even after controlling for other factors.