Articles tagged with Cancer Patients
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Researchers identified 2,314 genetic changes in polyps and adjacent mucosa, revealing potential drug targets for colorectal cancer prevention. The study also found similarities between premalignant and cancerous tissue, suggesting that polyps with more genetic changes may be more likely to develop into CRC.
A phase I clinical trial showed that abemaciclib achieved durable clinical activity in patients with breast cancer, non-small cell lung cancer, glioblastoma, and melanoma. Radiographic responses were observed for some patients with hormone receptor-positive breast cancer and NSCLC.
The Damon Runyon Cancer Research Foundation has selected five physician-scientists to receive the Physician-Scientist Training Award, providing them with resources to pursue cancer research. The awardees will receive grants totaling $2.3 million to aid their work in addressing the growing need for cancer research.
Researchers at Dana-Farber Cancer Institute present studies on the influence of tumor location on colorectal cancer survival, breast cancer clinical trial participation among older patients, and support for medical marijuana use in children with cancer. The findings suggest that consistent reporting of tumor location is crucial for imp...
A new study shows success with a combination therapy of the sugar 2-Deoxy-D-glucose (2-DG) and fenofibrate, which selectively starves slow-growing cancer cells while sparing normal cells. This approach eliminates toxic chemotherapy side effects, paving the way for non-toxic treatments for various cancers.
Researchers discover USP14 as a promising biomarker for predicting endometrial cancer recurrence. Women with high levels of USP14 are seven times more likely to recur than those with low levels, highlighting the potential for tailored treatment approaches.
The Samfund, a Boston-based cancer organization, will receive $8,500 from ASTRO for its work in supporting young adult cancer survivors financially. The grant funding will support the development of new financial programs and tools to aid in recovery.
A new study finds HIV-infected patients are more likely to lack cancer treatment for various cancers, including head and neck, upper gastrointestinal tract, and lung cancers. The disparity remains after adjusting for insurance status and comorbidities.
A new study published in Nature Medicine highlights the potential of big data to unlock the secrets inside cancer cells and enable more effective personalised treatments. The study proposes a blueprint for sharing patient data to improve patient outcomes.
Analysis of NCDB data shows that patients who received four quality measures had significantly higher overall median survival, increasing more than three-fold. However, compliance with these measures varies widely among patients, with only 13% receiving all four interventions.
Researchers from Memorial Sloan Kettering Cancer Center share results of experience with over 500 patients with pulmonary metastases from STS, identifying prognostic factors associated with improved survival. The study found that leiomyosarcoma histologic subtype, primary tumor size, and minimally invasive resections were significantly...
A genetic variation in the VAC14 gene is highly associated with docetaxel-induced peripheral neuropathy in prostate cancer patients. This finding could lead to more personalized treatment approaches and reduced side effects.
Research shows that 1 in 5 colorectal cancer patients are depressed at diagnosis, and this can significantly impact their quality of life. The study highlights the importance of considering psychological factors in patient care and support.
Boston Cancer Support, a nonprofit organization, will receive an $8,500 ASTRO Survivor Circle grant to support its work providing patient transportation and online resources. The organization aims to alleviate one of the largest issues faced by cancer patients: affordable transportation to treatments.
The Society of Surgical Oncology and European Society of Surgical Oncology propose a global curriculum to address training variations and inadequacies. The curriculum aims to create a robust workforce of well-trained surgical oncologists to meet the growing need resulting from the rising global cancer burden.
A new chemical sensor developed by Polish researchers can detect the presence of neopterin, a biomarker for certain cancers. The sensor uses molecular imprinting technology to capture molecules of neopterin from body fluids, with high accuracy and selectivity.
The report, based on over 3,000 patient surveys, sheds light on the physical, emotional, financial, practical, and informational needs of cancer patients during and after treatment. It aims to inform program development and address patient needs throughout their continuum of care.
Researchers discovered that cancer cells can escape the immune system by disabling the NLRC5 gene, which regulates MHC class I genes. This finding provides a new biomarker for predicting cancer patient survival and could lead to novel therapeutic strategies.
A new study found that cancer increases the risk for certain health issues beyond normal aging, including declines in activities of daily living and physical function. However, having a cancer diagnosis did not increase the likelihood of developing arthritis or vision/hearing problems, and did not exacerbate existing conditions.
A study published in Cancer Cell identified a third class of ACC, associated genes, and potential treatment targets. The research aims to provide better treatments for this rare cancer with significant side effects from current therapies.
Scientists at Helmholtz Munich discovered that fasting induces the production of a protein called GADD45β, which reduces fatty acid absorption in the liver and improves sugar metabolism. This finding holds promise for therapeutic intervention in metabolic diseases like type 2 diabetes.
A new study by researchers at the University of Pennsylvania's Abramson Cancer Center found that testing non-breast cancer genes in high-risk women does not add clinical benefit. The study analyzed a large panel of genes and found that many variants were of uncertain significance, adding complexity to genetic counseling.
A new staging system aims to explain revision rhinoplasty complexity and manage patient expectations. The PGS Staging System assesses three components: problem, graft, and previous surgical procedures, as well as a 'patient expectations' component.
Researchers found no association between cancer and a decreased risk for Alzheimer's disease, contrary to previous studies. Higher mortality rates among cancer patients suggest other factors contribute to the development of the neurodegenerative disorder.
Loyola researchers identified a tumor gene that predicts survival outcomes in mouth and tongue cancer patients. The spectrin gene is expressed in 4.6 times more likely to die, requiring more aggressive treatment.
Five teams of cancer researchers received a total of $1 million to advance 'innovation in collaboration' through new research projects. The awards will support novel collaborations between senior and junior researchers, exploring questions arising from existing SU2C-supported Teams.
Dr. Murtaza and Dr. Antoni Ribas are awarded $200,000 to investigate whether microbiome analysis can predict patient response to immunotherapy in melanoma patients. Their study aims to analyze the relationship between microbial composition and immunotherapy outcomes.
A large study found a significant association between long-term exposure to fine particulate matter and an increased risk of mortality from various cancers, including breast and lung cancer. The study suggests that reducing air pollution could have a substantial impact on cancer deaths in urban populations.
Cancer drug costs have increased by six times over the past decade, with newly approved medications costing an average of $11,325 per month, compared to $1,869 for those introduced in 2000. This trend may impact patients' ability to access these drugs and their financial burden.
A recent cancer diagnosis was associated with an increased risk of mental health disorders, including depression and anxiety, peaking in the first week after diagnosis. The study also found increased use of psychiatric medications among patients with cancer, remaining elevated two years post-diagnosis.
A clinical trial found narrow band imaging (NBI) significantly reduces bladder tumor recurrence in low-risk patients compared to conventional TURBT surgery. NBI detected small tumors that might be overlooked by white light cystoscopy, leading to a 5.6% recurrence rate versus 27.3% with traditional methods.
A new gene testing technology has been developed to identify mutations and prioritize variants in breast and ovarian cancer genes. The method reveals gene variants that were missed by conventional genetic testing, increasing the number of patients that can be properly diagnosed.
Leading UK oncologists argue that staying in the EU is crucial to maintaining the country's prominent role in cancer research and care. The authors point out the benefits of EU-wide cooperation, including improved standards of care, research, and patient rights, as well as strengthened collaboration with EU partners.
Researchers found that about 5% of patients experienced unexpected relapses of cancer after laparoscopic radical cystectomy (LRC) despite favorable pathology. The use of pneumoperitoneum during LRC may have played a role in these recurrences, according to the study published in The Journal of Urology.
A study found that patients with lower literacy levels tend to visit websites promoting products or services, while those with higher education seek non-commercial sites. The study highlights the need for clinicians to guide patients towards reputable online health information sources.
A new study reveals how retroviral DNA insertion complexes hunt for suitable spots and insert rapidly, with search times exceeding 2-3 seconds and insertion happening in under half a second at chosen sites. The findings could improve treatments for HIV infection and make gene therapy safer and more efficient.
A new study found that organ recipients with a history of cancer are at a higher risk of dying from any cause, dying from cancer, or developing a new cancer. The association between these outcomes did not vary by the type of transplanted organ, according to researchers at St. Michael's Hospital.
A systematic review of scientific literature found that taking low-dose aspirin alongside cancer treatment can reduce mortality and cancer spread by up to 20%. Researchers from Cardiff University suggest this may be due to a mutation in PIK3CA, which appears to explain the reduction in colon cancer mortality.
A study analyzing 727 articles found that 45% of media coverage about celebrity diagnoses mentioned double mastectomy. Meanwhile, the number of women undergoing double mastectomy at a Michigan hospital nearly five-fold during this time. The
In a clinical trial, half of 25 patients with Merkel cell carcinoma experienced substantial tumor shrinkage lasting nearly three times as long as conventional chemotherapy. Several patients had no remaining evidence of disease. The results suggest that immunotherapy drugs may be effective for other virus-associated cancers.
The demand for radiotherapy is expected to increase by 16% between 2012 and 2025, with prostate cancer cases projected to rise by 24%. This is due to an aging population in Europe, with four million new cancer patients expected in 2025. The study's authors aim to help policymakers plan for increased radiotherapy services.
A new study finds that patients with advanced cancer often view palliative care as a stigma due to its association with death. Experts suggest that education and rebranding could help break down this stigma, promoting a more positive view of the service.
A recent study reveals that cancer patients and families perceive palliative care as synonymous with death, despite its benefits in improving quality of life. The researchers call for a rebranding of palliative care to address the stigma and promote earlier access to supportive care.
Researchers at Ohio State University found that SPF30 sunscreens delayed melanoma onset in a mouse model by 80% when applied prior to UVB light exposure. The study suggests the potential of these sunscreens as effective melanoma-preventing agents.
The International Cancer Genome Consortium (ICGC) has launched ICGCmed, a platform that links genomic data with clinical information to guide personalized cancer treatment. The initiative aims to accelerate the movement of genomic discoveries into the clinic.
A phase I study of LOXO-101 demonstrated efficacy in reducing tumors in six patients with TRK fusion-positive cancers, including sarcoma, thyroid, and non-small cell lung. The study showed significant tumor regression in all six patients, with one patient experiencing a 17% tumor reduction.
A study from MD Anderson Cancer Center reveals a strong association between hepatitis C and certain head and neck cancers, such as oropharyngeal and nonoropharyngeal cancers. The findings have significant implications for screening and treatment of both conditions.
A new study found that only 50% of patients with locally advanced rectal cancer in the US receive the recommended standard therapy, which has increased over the past decade. Socioeconomic factors such as facility volume, race/ethnicity, insurance status, and education level are associated with a lower chance of receiving this treatment.
The SU2C Catalyst program will accelerate cancer research using funding and materials from pharmaceutical companies. Collaborative studies will investigate new compounds and approved agents for various uses, with a focus on prevention, detection and treatment.
Researchers found patients with autism have higher gene mutations that drive cancer, but lower cancer rates. Autistic patients have significantly higher rates of DNA variation in oncogenes and are less likely to have a co-occurring diagnosis of cancer.
A clinical trial found that using PET imaging to guide chemotherapy significantly increases remission rates and reduces toxic side effects in advanced Hodgkin lymphoma patients. The study showed a promising approach to tailor treatment to individual patients, leading to a potential new standard of care.
Researchers developed a novel method to measure mortality risk in elderly cancer patients with multiple diseases, providing a more accurate assessment than current survival rates. The approach uses machine learning and calculates the 'omega factor,' which compares a patient's cancer mortality risk to their overall mortality risk.
A new study found that married patients with cancer fare better than unmarried ones, but the benefits vary by demographics. Unmarried individuals, particularly men, experience higher mortality rates compared to their married counterparts. The study also showed that birthplace and acculturation impact cancer survivorship.
A public repository of patient-derived cancer models has been established to share this technique widely. The Public Repository of Xenografts (PRoXe) contains biopsy tissue collected from patients with leukemia and lymphoma, allowing researchers worldwide to access the portal and create PDX models for testing drugs.
Research found unmarried cancer patients had higher death rates than married patients, with whites benefiting the most from marriage. Hispanic and Asian Pacific Islander cancer patients who were born in the US experienced a greater benefit than those born outside the country.
Researchers found that common treatments for prostate cancer can suppress the immune system, preventing immunotherapies from working effectively. The study suggests careful regulation of treatment timing and dosage to maximize anti-tumor effects and prevent relapse.
A study of 70 elderly patients found that diverting urine through a single stoma resulted in lower operative times, blood loss, and hospital stays compared to ileal conduit diversion. Quality of life showed no significant difference between the two groups.
A national study found that a shorter, intensive radiation therapy schedule of about 5.5 weeks was comparable to the standard 8-week regimen in terms of controlling cancer, while also reducing treatment duration and costs. The researchers reported slightly more mild side effects in patients receiving the shorter schedule.
A phase 2 clinical trial found that afatinib significantly extended time to disease progression in patients with advanced urothelial cancer and at least one of two specific genetic abnormalities. The treatment also showed promise for patients without these mutations, although the response rate was lower.
A new study by Tenovus Cancer Care and the Royal College of Music found that singing in a choir for just 1 hour boosts levels of immune proteins in people affected by cancer. The research also showed significant reductions in stress hormones and increases in cytokines, which can boost the body's ability to fight serious illness.