Articles tagged with Cancer Patients
Research found that advanced age, black ethnicity, and pre-existing illnesses like cancer significantly increase the likelihood of bowel obstruction in hospitalized ischemic stroke patients. These complications can worsen recovery chances and lead to increased hospital length of stay and costs.
Researchers at the University of Cincinnati have discovered that a human cancer-causing gene called DEK can be detected in the plasma of head and neck cancer patients. High levels of DEK may indicate better outcomes for patients, while low levels are associated with advanced cancers.
Most recurrences of HPV-positive oropharyngeal cancer can be detected through imaging and physical exams within 6 months after treatment. The study found that disease characteristics, such as lymph node size and number, increase the likelihood of recurrence.
A large-scale analysis of patient records found that chemotherapy before radiation therapy did not improve overall survival rates for head and neck cancer patients. Patients who received concurrent chemotherapy and radiation had slightly longer median overall survival times compared to those receiving chemotherapy alone.
A large-scale analysis of patient records found that induction chemotherapy did not improve overall survival rates or increase the likelihood of receiving a full course of radiation therapy. The study compared more than 8,000 patients who received induction chemotherapy with those who received concurrent chemoradiation.
A combination of durvalumab and tremelimumab has been found to be effective in treating advanced non-small cell lung cancer patients, with 23% achieving a complete or partial response. The treatment also appears to be active in PD-L1-negative tumors.
Colorectal cancer patients require follow-up colonoscopy after surgery to detect second cancers and polyps, with recommended intervals varying from one to nine years. The US Multi-Society Task Force updates guidelines to emphasize the role of colonoscopy in post-surgical surveillance.
Two leading research groups independently discovered ONC201's ability to activate the integrated stress response, a powerful anti-cancer pathway. This understanding supports Oncoceutics' oncology indications and demonstrates ONC201's potential as an important therapeutic.
Researchers found that viewing graphic anti-smoking images on cigarette packs triggers activity in brain areas involved in emotion, decision-making and memory. The findings suggest these images could effectively warn smokers about cigarettes' health consequences and motivate a change in behavior.
Researchers at MD Anderson Cancer Center proposed a new staging system for HPV-related oropharyngeal cancer, which better separates patients with different survival rates. The new groupings were proven to have greater predictive power than the current system, particularly in identifying stage III disease with a high risk of death.
The Cancer Treatment Centers of America is hosting its second Annual New Treatments in Oncology (ANTO) conference on March 5 at the W Scottsdale hotel. The event will feature leading oncologists discussing recent advances and innovations in cancer research, treatment options, and patient care.
A UCLA study reveals that cancer surgery significantly increases the risk of injuries and age-related health issues in older patients, leading to prolonged hospital stays, increased healthcare costs, and a higher risk of death. The study highlights the importance of discussing potential events with doctors before surgery.
A new test has shown that patients with advanced bowel cancer who have high levels of two proteins can benefit from a combination of drugs, leading to improved cancer growth. The test could help select the best treatment for each individual patient, potentially improving survival rates and quality of life.
Cancer patients face financial distress due to rising medication costs, according to Dr. Scott Ramsey's editorial. To address this issue, policy interventions are proposed, including price negotiations with manufacturers and greater transparency of pricing.
Researchers analyze 500 scientific articles to develop a mathematical model for muscle-invasive bladder cancer. They identify potential biomarkers and clinical parameters to accurately determine cancer stage and develop individual treatment strategies.
The Journal of Pain Research publishes commentary on terminology of chronic pain, highlighting the need to redefine terms to better understand and treat patients. The authors suggest using origin- and generator-based terms to improve diagnosis and treatment outcomes.
Researchers found four Ly6 genes are overexpressed in various cancers, leading to poorer survival rates and drug resistance. The study uses big data analysis to identify novel targets for new drugs.
Researchers at Johns Hopkins University found a possible marker for recurring HPV-linked oropharyngeal cancers. The study suggests that an increase in E6 antibody levels after treatment may indicate a higher risk of cancer returning.
A 28-year-old transgender woman experienced a delay in testicular cancer diagnosis due to inadequate access to insurance coverage and transportation challenges. The case study emphasizes the importance of addressing biopsychosocial needs and creating venues for medical providers to learn appropriate care for transgender patients.
A set of risk factors can predict the magnitude of survival benefit offered by radiation therapy following breast cancer surgery. Radiation therapy provides a significant survival benefit for patients with more aggressive cancer, particularly those with higher prognostic scores.
A University of Georgia study found that cancer patients' loved ones search online for information on treatment options and prevention strategies, but are less likely to seek emotional support from social media forums. The study's author aims to use this information to develop effective online cancer prevention messages.
A study published in Gut journal reveals a 10-fold difference in bowel cancer cases and deaths worldwide, with higher incidence linked to economic development. The adoption of a Western lifestyle is suspected to contribute to the rising rates, particularly in low- and middle-income countries.
Men and women in Appalachia continue to have higher cancer incidence rates compared with those in the rest of the United States. Lifestyle changes and improved healthcare are helping narrow the gap between Appalachian and non-Appalachian populations.
The iCat study successfully used clinical genomic sequencing to recommend therapy or diagnose changes in children with solid tumors. The findings support the use of personalized treatment based on tumor genetic characteristics, fueling potential drug development for pediatric and rare adult tumors.
A collection of articles explores fertility issues in patients with cancer, including the legal framework and potential solutions for disputes involving donated genetic material. The articles also highlight the importance of oncologists providing fertility care to their patients.
A study by Baylor College of Medicine found that genetic testing can identify the cause of childhood cancer in 40% of patients, including mutations not previously associated with the disease. The test can also reveal potential clinical targets for treatment and risk of hereditary diseases.
Researchers will test peripherally-restricted cannabinoids (PRCBs) to alleviate oral cancer and chemotherapy-induced neuropathic pain symptoms. The five-year study aims to determine the antitumor potential of PRCBs, their effectiveness against cancer pain, and potential tolerance development.
Research by Michigan Medicine found that nearly 15% of colorectal cancer patients were diagnosed before age 50, often with more advanced disease. Younger patients had better survival rates due to aggressive treatment, suggesting the need for improved long-term survivorship resources.
The American College of Physicians issues guidelines for evaluating blood in the urine as a sign of cancer. Doctors should confirm heme-positive results with microscopic urinalysis before initiating further evaluation in asymptomatic adults. Urology referral is recommended for cystoscopy and imaging in adults with microscopically confi...
A study of US data found that one in seven colorectal cancer patients is younger than 50 years old, often presenting with advanced stage disease. However, these patients tend to receive more aggressive therapy and have a slightly longer survival rate without recurrence.
Researchers found African-American children and adolescents with Hodgkin lymphoma had significantly lower overall survival rates at 25 years compared to their white and Hispanic counterparts. The study, published in Pediatric Blood & Cancer, analyzed data from over 7,800 patients across Florida and the US.
A University of Colorado study found distinct genetic drivers in colorectal cancer among young and old patients, with potential implications for targeted therapies.
Researchers found that a 56-day interval after chemoradiotherapy is the best timeframe for overall survival and tumor downstaging. The study analyzed data from nearly 12,000 patients with advanced stage localized rectal cancer.
A study comparing end-of-life care practices among US, European, and Canadian countries found that the US has lower hospital deaths and days spent in hospitals in the last six months of life. However, it also performs poorly in other aspects of end-of-life care, such as high-tech interventions.
A study found that family members perceive better end-of-life care for patients who received hospice care for longer periods, avoided intensive care unit admissions, and died outside the hospital. These findings suggest that multifaceted approaches can improve preference-sensitive care and overall quality of end-of-life care.
A study of end-of-life care practices in seven developed countries reveals that the US performs poorly in terms of high-tech interventions and hospital utilization. The US has the lowest proportion of deaths in the hospital, but still admits over 40% of cancer patients to the ICU in their last 6 months of life.
A new study uses natural laws to predict how cancers evolve over time, potentially leading to personalized treatment. The research suggests that doctors could use mathematical formulas to anticipate a cancer's growth and development, enabling them to choose the most effective treatments.
A new study suggests that combining PARP inhibitors with c-MET inhibitors may improve treatment outcomes for patients with breast cancer and high c-MET expression levels.
Adolescent girls living in high-poverty communities and majority Hispanic communities were more likely to have received the HPV vaccine. The poverty level of the community was also an important factor, with higher rates found in areas with lower socioeconomic status.
A randomized clinical trial found that ED-initiated palliative care consultations improved quality-of-life scores and median survival without shortening survival. The study suggests that ED visits can provide a unique opportunity for improved access to palliative care.
A thin, stretchable film developed by University of Michigan researchers could enable doctors to catch cancer recurrence earlier with more effective treatment. The film produces circularly polarized light, a crucial ingredient in early warning systems, making it potentially simpler and less expensive to produce.
The Society for Cardiovascular Angiography and Interventions has released a consensus statement providing guidance for treating patients with concomitant cardiovascular disease and cancer. The document aims to increase the competency of cardiovascular professionals in caring for cancer patients, who are expected to increase to 20 milli...
A new study reveals that adult retinoblastoma survivors are at higher risk of developing various medical problems, including second cancers, compared to unaffected individuals. Despite this, the majority of survivors report excellent general health and minimal long-term impact on their psychological or socio-economic outcomes.
A new study published in JAMA Oncology found that solid-organ transplant recipients have a significantly higher cancer death rate than the general population. The research, which analyzed data from over 11,000 transplanted patients between 1991 and 2010, revealed that SOTRs were at increased risk of cancer death regardless of age, sex,...
A recent study published in PLOS ONE found that statins increased overall survival among late-stage SCLC patients, while other medications showed no benefit. Radiotherapy was also identified as an independent predictor of survival.
Scientists at USC have discovered the Achilles heel of hepatocellular carcinoma, a leading cause of cancer deaths worldwide. Researchers identified the carcinogenic pathway of stem cell marker NANOG, which promotes cancer spread by rewiring metabolism in mitochondria.
The Association for Cancer Physicians has released a new strategy to improve cancer patient services and outcomes in the UK. The comprehensive plan focuses on delivering excellent and safe medical oncology care, contributing to NHS development, and providing innovative approaches to cancer care.
Researchers have identified NORAD, a long noncoding RNA, as crucial in maintaining proper chromosome numbers. Absence of NORAD leads to genomic instability and cells losing or gaining whole chromosomes.
A study by Case Western Reserve University School of Medicine found that a tailored video education program improved cancer patients' knowledge and reduced negative attitudes towards clinical trials. The PRE-ACT program was more effective than text-based information in encouraging participants to consider clinical trials.
A study published in PLOS Genetics found that members of four unrelated US families shared an identical BAP1 gene mutation, which increases cancer risk. The researchers traced the ancestral connection back to a couple who immigrated from Germany in the early 1700s.
A recent study published in the Journal of the American Medical Association found that paid sick leave can significantly reduce the financial burden on cancer patients. The study, which surveyed over 1,300 patients with stage 3 colorectal cancer, showed that those with paid sick leave were nearly twice as likely to retain their jobs af...
A new analysis found that nearly 60% of metastatic cancer patients experience some change in employment due to illness. Controlling symptoms is key for many patients to remain employed, with better performance status and non-Hispanic White ethnicity/race being associated with continued work.
A study found that postmenopausal women with periodontal disease were more likely to develop breast cancer than those without the condition. The risk was particularly high among women who had quit smoking recently, suggesting a potential link between bacterial exposure and breast cancer risk.
A study published in Gastrointestinal Endoscopy found ESD to be a safe and effective treatment for superficial pharyngeal cancer, achieving an en bloc resection rate of 100% and complete resection rate of 79.5%. The procedure showed minimal side effects, with a three-year overall survival rate of 97.7%.
A study published in The Journal of Urology found that patients with low mental health self-assessments before radical cystectomy had higher rates of high-grade complications, highlighting the importance of preoperative assessment.
Researchers found that family members of CUP patients have a higher risk of developing cancers such as lung, pancreas, and colon cancer. The study identified specific sites where these cancers may originate, providing new guidance for physicians and potentially improving treatment outcomes.
The ESMO Asia 2015 Congress brought together cancer experts to discuss the latest treatment solutions and patient care. Researchers presented promising findings on immunotherapy and targeted therapy for difficult-to-treat head-and-neck cancers, as well as combination therapies for endocrine-resistant breast cancer.
A new study by the American College of Surgeons found that preoperative use of blood-thinning drugs does not increase major bleeding rates in cancer patients undergoing major operations. The study also revealed a lower risk of developing deep vein thrombosis and pulmonary embolism in patients who received preoperative VTE prophylaxis.
New research reveals that current genome analysis approaches miss detecting complex cancer mutations in well-known genes that could be targeted by existing drugs. The developed software tool, Pindel-C, identifies a large number of such events in critical cancer genes.
Improved screening and detection efforts have reduced cancer incidence and mortality rates in several common types of cancer in high-income countries. However, many low-and middle-income countries have seen a rise in cancer rates due to factors such as lifestyle changes and inadequate screening or prevention measures.