Articles tagged with Cancer Patients
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A University of Georgia study found that cancer patients' loved ones search online for information on treatment options and prevention strategies, but are less likely to seek emotional support from social media forums. The study's author aims to use this information to develop effective online cancer prevention messages.
A study published in Gut journal reveals a 10-fold difference in bowel cancer cases and deaths worldwide, with higher incidence linked to economic development. The adoption of a Western lifestyle is suspected to contribute to the rising rates, particularly in low- and middle-income countries.
Men and women in Appalachia continue to have higher cancer incidence rates compared with those in the rest of the United States. Lifestyle changes and improved healthcare are helping narrow the gap between Appalachian and non-Appalachian populations.
The iCat study successfully used clinical genomic sequencing to recommend therapy or diagnose changes in children with solid tumors. The findings support the use of personalized treatment based on tumor genetic characteristics, fueling potential drug development for pediatric and rare adult tumors.
A collection of articles explores fertility issues in patients with cancer, including the legal framework and potential solutions for disputes involving donated genetic material. The articles also highlight the importance of oncologists providing fertility care to their patients.
A study by Baylor College of Medicine found that genetic testing can identify the cause of childhood cancer in 40% of patients, including mutations not previously associated with the disease. The test can also reveal potential clinical targets for treatment and risk of hereditary diseases.
Researchers will test peripherally-restricted cannabinoids (PRCBs) to alleviate oral cancer and chemotherapy-induced neuropathic pain symptoms. The five-year study aims to determine the antitumor potential of PRCBs, their effectiveness against cancer pain, and potential tolerance development.
Research by Michigan Medicine found that nearly 15% of colorectal cancer patients were diagnosed before age 50, often with more advanced disease. Younger patients had better survival rates due to aggressive treatment, suggesting the need for improved long-term survivorship resources.
The American College of Physicians issues guidelines for evaluating blood in the urine as a sign of cancer. Doctors should confirm heme-positive results with microscopic urinalysis before initiating further evaluation in asymptomatic adults. Urology referral is recommended for cystoscopy and imaging in adults with microscopically confi...
A study of US data found that one in seven colorectal cancer patients is younger than 50 years old, often presenting with advanced stage disease. However, these patients tend to receive more aggressive therapy and have a slightly longer survival rate without recurrence.
Researchers found African-American children and adolescents with Hodgkin lymphoma had significantly lower overall survival rates at 25 years compared to their white and Hispanic counterparts. The study, published in Pediatric Blood & Cancer, analyzed data from over 7,800 patients across Florida and the US.
A University of Colorado study found distinct genetic drivers in colorectal cancer among young and old patients, with potential implications for targeted therapies.
Researchers found that a 56-day interval after chemoradiotherapy is the best timeframe for overall survival and tumor downstaging. The study analyzed data from nearly 12,000 patients with advanced stage localized rectal cancer.
A study comparing end-of-life care practices among US, European, and Canadian countries found that the US has lower hospital deaths and days spent in hospitals in the last six months of life. However, it also performs poorly in other aspects of end-of-life care, such as high-tech interventions.
A study found that family members perceive better end-of-life care for patients who received hospice care for longer periods, avoided intensive care unit admissions, and died outside the hospital. These findings suggest that multifaceted approaches can improve preference-sensitive care and overall quality of end-of-life care.
A study of end-of-life care practices in seven developed countries reveals that the US performs poorly in terms of high-tech interventions and hospital utilization. The US has the lowest proportion of deaths in the hospital, but still admits over 40% of cancer patients to the ICU in their last 6 months of life.
A new study uses natural laws to predict how cancers evolve over time, potentially leading to personalized treatment. The research suggests that doctors could use mathematical formulas to anticipate a cancer's growth and development, enabling them to choose the most effective treatments.
A new study suggests that combining PARP inhibitors with c-MET inhibitors may improve treatment outcomes for patients with breast cancer and high c-MET expression levels.
Adolescent girls living in high-poverty communities and majority Hispanic communities were more likely to have received the HPV vaccine. The poverty level of the community was also an important factor, with higher rates found in areas with lower socioeconomic status.
A randomized clinical trial found that ED-initiated palliative care consultations improved quality-of-life scores and median survival without shortening survival. The study suggests that ED visits can provide a unique opportunity for improved access to palliative care.
A thin, stretchable film developed by University of Michigan researchers could enable doctors to catch cancer recurrence earlier with more effective treatment. The film produces circularly polarized light, a crucial ingredient in early warning systems, making it potentially simpler and less expensive to produce.
The Society for Cardiovascular Angiography and Interventions has released a consensus statement providing guidance for treating patients with concomitant cardiovascular disease and cancer. The document aims to increase the competency of cardiovascular professionals in caring for cancer patients, who are expected to increase to 20 milli...
A new study reveals that adult retinoblastoma survivors are at higher risk of developing various medical problems, including second cancers, compared to unaffected individuals. Despite this, the majority of survivors report excellent general health and minimal long-term impact on their psychological or socio-economic outcomes.
A new study published in JAMA Oncology found that solid-organ transplant recipients have a significantly higher cancer death rate than the general population. The research, which analyzed data from over 11,000 transplanted patients between 1991 and 2010, revealed that SOTRs were at increased risk of cancer death regardless of age, sex,...
A recent study published in PLOS ONE found that statins increased overall survival among late-stage SCLC patients, while other medications showed no benefit. Radiotherapy was also identified as an independent predictor of survival.
Scientists at USC have discovered the Achilles heel of hepatocellular carcinoma, a leading cause of cancer deaths worldwide. Researchers identified the carcinogenic pathway of stem cell marker NANOG, which promotes cancer spread by rewiring metabolism in mitochondria.
The Association for Cancer Physicians has released a new strategy to improve cancer patient services and outcomes in the UK. The comprehensive plan focuses on delivering excellent and safe medical oncology care, contributing to NHS development, and providing innovative approaches to cancer care.
Researchers have identified NORAD, a long noncoding RNA, as crucial in maintaining proper chromosome numbers. Absence of NORAD leads to genomic instability and cells losing or gaining whole chromosomes.
A study by Case Western Reserve University School of Medicine found that a tailored video education program improved cancer patients' knowledge and reduced negative attitudes towards clinical trials. The PRE-ACT program was more effective than text-based information in encouraging participants to consider clinical trials.
A study published in PLOS Genetics found that members of four unrelated US families shared an identical BAP1 gene mutation, which increases cancer risk. The researchers traced the ancestral connection back to a couple who immigrated from Germany in the early 1700s.
A recent study published in the Journal of the American Medical Association found that paid sick leave can significantly reduce the financial burden on cancer patients. The study, which surveyed over 1,300 patients with stage 3 colorectal cancer, showed that those with paid sick leave were nearly twice as likely to retain their jobs af...
A new analysis found that nearly 60% of metastatic cancer patients experience some change in employment due to illness. Controlling symptoms is key for many patients to remain employed, with better performance status and non-Hispanic White ethnicity/race being associated with continued work.
A study found that postmenopausal women with periodontal disease were more likely to develop breast cancer than those without the condition. The risk was particularly high among women who had quit smoking recently, suggesting a potential link between bacterial exposure and breast cancer risk.
A study published in Gastrointestinal Endoscopy found ESD to be a safe and effective treatment for superficial pharyngeal cancer, achieving an en bloc resection rate of 100% and complete resection rate of 79.5%. The procedure showed minimal side effects, with a three-year overall survival rate of 97.7%.
A study published in The Journal of Urology found that patients with low mental health self-assessments before radical cystectomy had higher rates of high-grade complications, highlighting the importance of preoperative assessment.
Researchers found that family members of CUP patients have a higher risk of developing cancers such as lung, pancreas, and colon cancer. The study identified specific sites where these cancers may originate, providing new guidance for physicians and potentially improving treatment outcomes.
The ESMO Asia 2015 Congress brought together cancer experts to discuss the latest treatment solutions and patient care. Researchers presented promising findings on immunotherapy and targeted therapy for difficult-to-treat head-and-neck cancers, as well as combination therapies for endocrine-resistant breast cancer.
A new study by the American College of Surgeons found that preoperative use of blood-thinning drugs does not increase major bleeding rates in cancer patients undergoing major operations. The study also revealed a lower risk of developing deep vein thrombosis and pulmonary embolism in patients who received preoperative VTE prophylaxis.
New research reveals that current genome analysis approaches miss detecting complex cancer mutations in well-known genes that could be targeted by existing drugs. The developed software tool, Pindel-C, identifies a large number of such events in critical cancer genes.
Improved screening and detection efforts have reduced cancer incidence and mortality rates in several common types of cancer in high-income countries. However, many low-and middle-income countries have seen a rise in cancer rates due to factors such as lifestyle changes and inadequate screening or prevention measures.
A new study reveals that Latinos from Mexico have the lowest chance of getting colorectal cancer, while those from Central or South America are diagnosed with the disease before age 50 at a higher rate. The research aims to pave the way for personalized cancer care and reduce disparities in treatment
Thyroid cancer patients report poor quality of life after diagnosis and treatment compared to other patients with more lethal cancers. Researchers found that thyroid cancer survivors reported an average quality of life score of 5.56 out of 10, which is worse than other cancer types.
A single dose of psilocybin significantly decreases anxiety and depression in cancer patients, with positive effects lasting up to 6 months. The study suggests that psilocybin may be a sufficient treatment for mood disturbances in cancer patients.
A study identified significant differences in cancer genome sequencing procedures and quality among research institutions, leading to inconsistencies in detected mutations. A reference mutation dataset has been established to improve procedures for identifying true somatic mutations in cancer genomes.
Recent studies present new data on the myRisk Hereditary Cancer test, highlighting its ability to identify patients with deleterious mutations who may have been missed by traditional genetic testing. The test demonstrated a significant increase in identifying BRCA-related mutations among those tested without BRCA1/2 results.
A gold standard data record has been established to improve cancer genome analysis and detect somatic mutations reliably. The record, obtained from interlaboratory testing, provides a basis for laboratories to evaluate their bioinformatic methods and thresholds for detecting specific mutations.
Research from the University of Pennsylvania School of Medicine found that pre- and post-test counseling for genetic mutations increases knowledge and decreases anxiety in BRCA-negative patients. After testing, most women reported declines in general anxiety and improvements in genetic knowledge.
A Singapore-led team, with support from the Swiss Rising Tide Foundation, is conducting a Phase III clinical trial to evaluate Aspirin as secondary prevention therapy for patients with established colorectal cancer. The study aims to determine the effectiveness of Aspirin in reducing cancer recurrence and mortality.
A phase I/II clinical trial found that acalabrutinib promotes high response rates and durable results in patients with relapsed chronic lymphocytic leukemia while producing minimal side effects. The drug's selective blockade of the BTK pathway may offer improved tolerability compared to other treatments.
Researchers developed a new index identifying concurrent but unrelated diseases among AYA cancer patients, highlighting prevalence of mental illness, obesity, and cardiovascular conditions. The AYA HOPE Comorbidity Index can predict service needs and improve treatment outcomes for young cancer patients.
A study of 87 CLL patients found 12 genetic mutations that can be targeted by therapies already available for other cancers, including PARP and BRAF inhibitors. These mutations were detected through next-generation sequencing and may offer new treatment options for patients who fail current therapies.
Yale researchers developed a high-dose flu vaccine strategy that lowered infection rates by 64% among patients with immune system cancers. The novel dosing schedule improved protection against all flu strains in 66% of patients, offering promising results for cancer patient populations.
Researchers report improvements in four children treated with gene therapy for Wiskott-Aldrich syndrome, including reduced bleeding events and improved immunologic symptoms. The treatment's long-term safety and efficacy remain to be assessed as the children are monitored for 15 years.
Scientists create virtual tumors to test drug treatments, achieving an 85-86% correlation with lab results. The goal is a patient-specific workflow for early diagnosis and effective treatment identification.
A new study in mice successfully preserved fertility using ovarian follicles, producing live births and addressing concerns about reintroducing cancer cells. The technique could be beneficial for women with cancer who cannot afford to delay treatment.
The EurocanPlatform project has led to the establishment of Cancer Core Europe, a long-term initiative between six leading cancer centers aiming to create a single virtual 'e-hospital' with powerful translational platforms. This will provide robust computational biology pipelines and standardized imaging for personalized cancer medicine.
Researchers found that different regions of a single tumor shared varying levels of genetic mutations, ranging from 67% to 93%. This variation could make it harder for targeted therapies to work effectively. The study's findings have significant implications for treatment recommendations and patient care.
A feasibility study found that women with breast cancer experienced improved feelings of positivity, control, and meaning after tending small indoor 'garden bowls'. The benefits were attributed to the process of nurturing and reflecting on the garden, suggesting a simple ecotherapy-based intervention can have significant impacts.
Researchers at Kyoto University have discovered that an antibody called nivolumab may help patients with platinum-resistant ovarian cancer heal themselves by targeting the PD-1 signal. A phase II clinical trial found that most patients treated with nivolumab experienced a median overall survival of 20 months.
A study published in Radiology found that MRI-detected multicentric cancers are larger and potentially more aggressive than index cancers detected by mammography, necessitating treatment changes. In 25% of cases, these multicentric cancers were over 1 centimeter in size.