Articles tagged with Dentistry
A NJIT-led team has created an injectable hydrogel designed to recruit dental pulp stem cells and promote tissue growth in teeth after a root canal. The therapy mimics the body's natural growth factor signaling, promoting healing and regeneration of lost tooth pulp.
A study by researchers at UCSF found that e-cigarette use costs the US $15 billion annually in healthcare expenditures, with each user paying around $2,000 extra per year compared to non-users. The study, published in Tobacco Control, highlights the growing concern over health care costs associated with e-cigarette use.
A study published in Cell reveals that individuals with gum disease are more susceptible to developing arthritis due to alterations in immune cell precursors in the bone marrow. The researchers also found that this association may prompt a reconsideration of how bone marrow donors are selected.
Deleting or inhibiting a protein called lysine-specific demethylase 1 (LSD1) may curb the growth of oral squamous cell carcinoma tumors. The study found that disrupting LSD1 promotes anti-tumor immunity, which can help fight cancer. The discovery could lead to new and potentially more effective therapies for oral cancer patients.
Researchers at Tokyo University of Agriculture and Technology discovered that double-stranded RNA molecules can activate the immune system response leading to bone deterioration in gum disease. The study found that dsRNA triggers the differentiation of osteoclasts, cells responsible for breaking down bone, leading to increased bone ero...
Patients with a reported penicillin allergy have higher rates of dental implant failure. Alternative antibiotics prescribed during surgery also linked to increased failure rates. The study suggests that testing for actual allergies may improve outcomes.
Researchers tested if mothers' oral microbiome seeds a cariogenic community in children. They found that bacteria correlated between mothers and children were associated with lower risk of Early Childhood Caries (ECC). The study suggests poor maternal oral health may influence ECC risk through transmission of microbes.
Researchers created a dental tool that measures plaque acidity using an LED light and FDA-approved chemical dye, providing dentists with early warning signs of cavity development. The device can help limit the need for specific harmful bacteria tests and educate patients about sugar's impact on oral health.
A recent study found that sleep bruxism can lead to temporomandibular joint disorders due to increased mechanical loading. The research discovered that specific combinations of tooth shape and location during grinding significantly impact the risk of TMJ problems.
Oral health disparities persist despite improved overall health trends, disproportionately affecting marginalized groups. Research and policy initiatives are needed to make oral health care more affordable, accessible, and responsive to communities.
A series of studies by NYU researchers found that e-cigarette users have a distinct oral microbiome less healthy than nonsmokers but potentially healthier than cigarette smokers. The study also reveals altered immune responses, including increased inflammation and suppression of immune reactions.
A Swedish registry study found no increase in endocarditis cases among high-risk individuals since the removal of prophylactic antibiotics in dentistry. The study monitored over 76,000 high-risk individuals and 396,000 low-risk individuals from 2008 to 2018.
Researchers have designed a tiny and flat antenna for receiving and transmitting terahertz signals, enabling the miniaturization of THz devices. The new design integrates the antenna with the system, eliminating the need for bulky silicon lenses and reducing optical power required.
The study demonstrated that photodynamic therapy (PDT) using chlorin e-6 can effectively reduce bacterial plaque biofilms containing cariogenic microorganisms, including Streptococcus mutans. The treatment eliminated S. mutans and decreased total microorganisms by up to 3.7 units, with approximately 99% efficacy of antimicrobial activity.
A study by the University of Leeds found that changing drills from air-powered to electric drills can significantly reduce aerosol spray and create a safer environment for patients and dental teams. The research resulted in a 99.98% reduction in virus spread, potentially allowing millions more treatments to be carried out.
Researchers found a mussel-derived compound strengthens resin-dentin bond and improves its durability. The compound, N-(3,4-dihydroxyphenethy) methacrylamide (DMA), reduces nanoleakage and increases longevity of dental fillings.
Researchers created a model system to study the ultrasmall bacteria TM7 and found that they acquired a gene cluster encoding the arginine deiminase system, which helps them survive and multiply in the human oral cavity. This discovery suggests that TM7 may play a more protective role in oral health than previously thought.
Case studies show one in five children suffer from chalky tooth enamel, causing severe toothache and decay. Researchers from The D3 Group have found that albumin contamination blocks hardening of enamel on teeth growing inside the jaw, triggered by childhood illnesses.
A University of Otago study finds caries in wild primates occur at low frequencies but vary among groups, with distinct tooth patterns compared to fossil humans. The research provides a new perspective on human evolution and living primate behaviour.
A study of Edo-era Japanese skeletons reveals a prevalence of periodontal disease similar to modern times, with distinct bacterial species. Researchers analyzed dental calculus from 12 human skeletons and compared their oral microbiomes to modern samples, shedding light on the evolution of the oral microbiome.
The study found clear differences in bacterial community composition and functional profiles between healthy and diseased sites, with specific taxa associated with periodontal disease progression. The identification of key bacterial species and functions involved could help prevent permanent damage.
Researchers compared genetic expression profiles of canine acanthomatous ameloblastoma and human oral tumor ameloblastoma, finding similarities in molecular mutations. The study lays groundwork for potential translational medicine, as the dog model may represent a useful clinical model of the disease.
Researchers investigate the effect of local exhaust ventilation (LEV) devices on dental aerosols and droplets produced during procedures. LEV significantly reduces aerosol dispersion, with effects comparable to suction for ultrasonic scalers and substantial reductions for air-turbine handpieces.
A survey of US dentists found that an overwhelming majority believe nonsteroidal anti-inflammatory drug (NSAID)-acetaminophen combinations are as effective or more effective in managing dental pain as opioids. However, nearly half still prescribe opioids, highlighting a disconnect between their knowledge and prescribing habits.
Researchers at Graz University of Technology have developed a new production method for germanium-based photoinitiators, making them cheaper and more efficient. This enables their use in contact lenses, prostheses, and artificial human tissue, among other applications.
A new technique using in situ synchrotron X-ray microtomography has been developed to study the effects of acid on teeth. The technique enabled researchers to build clear 3D images of dentine's internal structure with sub-micrometre resolution, revealing that acid dissolves minerals at different rates in different structures of dentine.
A recent University at Buffalo study found that patients using proton pump inhibitors (PPIs) for heartburn had smaller probing depths in their gums, indicating less severe gum disease. The researchers suggest that PPIs' side effects may be linked to reduced periodontitis severity.
Researchers developed a novel approach to 3D image segmentation, segmenting the gaps between parts instead of contours, to automate tedious tasks. The technique demonstrates promising results in diagnosing TMJ-related issues and has potential applications in other fields.
Researchers found that both Gram-positive and Gram-negative bacteria induce the resorption of alveolar bone, a key component of periodontal tissue. The study suggests that positive and negative bacteria are responsible for periodontitis symptoms.
Danish adults have made significant strides in preserving their natural teeth and visiting the dentist more frequently. However, social disparities in dental health persist, with those from lower-income backgrounds receiving less preventive care.
New research found that using electric drills instead of air-driven drills reduces aerosol spray by 99.98%, creating a safer environment for patients and dental teams. This could lead to a significant increase in treatments carried out, addressing the growing backlog of patients waiting for dental care.
Researchers developed a 'phantom head' model to measure aerosol dispersal in dental procedures and determined the efficacy of HSCAHs, rubber dam, and high-volume aspiration in reducing bioaerosol levels. The study suggests that these mitigation strategies can greatly attenuate the risk of SARS-CoV-2 dispersion.
Jeffrey Ebersole, Sharon Grayden, and Stephen Bayne received the 2021 AADR Presidential Citation for their significant contributions to the Association. The citation honors individuals who have made lasting impacts on dental research and advancing the mission of the AADR.
Rosa, an Associate Professor at NUS Faculty of Dentistry, received the award for his work on atom-thin materials for biomedical applications and dental pulp regeneration. He will serve a two-year term on the IADR Board of Directors.
Dennis Sourvanos, a University of Pennsylvania graduate resident, received the AADR William B. Clark Fellowship for his work on novel biotherapies in hard and soft tissue regeneration. The fellowship supports clinical research in periodontology and aims to enhance evidence-based oral healthcare.
Alvaro Della Bona, University of Passo Fundo Professor, received the 2021 Wilmer Souder Award for his contributions to dental biomaterials research. He is recognized internationally for his publications and invited presentations on the topic.
Kiyoshi Koyano, a renowned prosthodontist, has received the IADR Distinguished Scientist Award for his outstanding research contributions to the field of prosthodontics and implants. He is recognized as a prominent scientist in Japan, with numerous international positions and publications on clinical practice and prosthodontics.
Researchers identified three oral inflammation phenotypes: high, low, and slow responses. The 'slow' response was found in subjects with low clinical responses and demonstrated a delayed strong inflammatory response. A novel protective mechanism, utilizing neutrophils, was also discovered to save tissue and bone during inflammation.
A team of researchers developed a novel mathematical model to determine the optimal student loan repayment strategy. Combining elements of quick payment and income-based repayment plans can save borrowers money. The model takes into account individual circumstances, including balance size and compounding interest rates.
Studies found Twitter's real-time Q&A sessions and semi-anonymous interactions can benefit students' engagement and confidence. However, barriers to Twitter's use in dental education include privacy concerns and professionalism issues.
A study by University of Illinois Chicago pediatric dentist Dr. Flavia Lamberghini tested asymptomatic pediatric dental patients and found a 2.3% SARS-CoV-2 positivity rate. The study suggests that PCR testing for COVID-19 in asymptomatic patients adds value to screening questionnaires.
A targeted opioid called NFEPP selectively activates opioid receptors in acidic tissues, relieving pain from colitis without causing severe side effects. Researchers are now collecting tissue samples to test NFEPP's ability to inhibit pain in the human gut and plan clinical trials.
Researchers found that ring-tailed lemurs can detect ripe cantaloupe from a distance of up to 56 feet using their sense of smell. The study demonstrates the first time primates track distant smells carried by wind.
A new study from the University of Michigan School of Dentistry confirms that low-dose naltrexone is a good option for patients with orofacial and chronic pain, reducing pain intensity and improving quality of life. Low-dose naltrexone works by targeting sensitized nervous cells to reduce pain threshold and sensitivity.
NYU College of Dentistry has been awarded a $1.9 million NIH grant to study the molecular mechanisms underlying mitochondrial permeability transition, a phenomenon that causes tissue damage during strokes and heart attacks. The research aims to develop new drugs that can protect against cell death and tissue damage.
Researchers at Imperial College London and King's College London suggest that dentists avoid using drills with air and water mixtures and carefully select drill rotation speeds to reduce aerosol generation. This approach can produce 60 times fewer aerosol droplets, allowing for safer dental procedures and increased patient access
The COVID-19 pandemic has underscored the importance of defining essential oral healthcare. A layered approach to essential oral healthcare allows for categorization and prioritization with available resources in mind, recognizing basic oral healthcare as an integral component of a healthcare system's essential services. The Internatio...
A study by dentists from RUDN University found that a change in the dominant side of chewing can cause early deterioration of dental implants. The researchers monitored 64 patients with dental implants and discovered that those who changed their chewing habits after surgery experienced more bone tissue formation pathologies.
A new study by NYU College of Dentistry found that half of US dentists experienced verbal or reputational aggression in the past year, while nearly a quarter endured physical aggression. The rates of patient aggression toward dentists are high and comparable with those reported in other health care settings.
A team of scientists at the University of Toronto has discovered the mechanism linking periodontal disease to other inflammatory conditions. The study found that neutrophil immune cell activity is the key factor connecting gum disease to heart disease, cancer, and other inflammatory conditions.
A team of dentists from RUDN University presented a new classification system for root canal shape changes, which can vary depending on the tooth part and patient age. The study used CT scans of 300 patients and identified four groups of shape changes to help dentists choose proper tools and treatment methods.
Researchers discovered that food-grade polymers can completely eliminate aerosolization of saliva droplets in dental settings. The polymers' viscoelastic properties restrict water aerosolization by creating snakelike strands that pull droplets back, preventing aerosolization.
Researchers at University of Saskatchewan are developing a unique saliva-based test to detect SARS-CoV-2 peptides in saliva, which is expected to be more sensitive, less invasive, and less expensive than current methods. The test aims to detect mild or asymptomatic COVID-19 cases and will be available by March 2021.
A University of Toronto team has been awarded a $1.5 million grant to study the impact of cannabis use on Indigenous oral health in Canada. The study will gather first evidence of the effects of cannabis on Indigenous populations, working in partnership with communities and public health authorities.
A new deep learning model accurately localises the exact location of mandibular canals in lower jaws, making dental implant operations faster and more efficient. The model surpasses existing methods, such as statistical shape models, and performs equally fast and accurately every time.
A new study published in Scientific Reports found that teeth contain annual layers, or cementum bands, that record an individual's life experiences, including reproduction and menopause. The research uses microscopic examination to reveal connections between tooth formation and other life stages.
Researchers found that patients prescribed opioids after tooth extraction reported worse pain, and half of prescribed opioids remained unused. The study suggests that alternatives such as nonsteroidal anti-inflammatory drugs or acetaminophen control pain better and improve patient satisfaction.
A molecule found in oranges, called nobiletin, has been shown to drastically reduce obesity in mice by reducing insulin resistance and blood fats. Researchers are now exploring its potential as a treatment for human obesity and related diseases, including heart disease and diabetes.
A new study led by NYU College of Dentistry researchers found that vaping alters the oral microbiome, making users more prone to inflammation and infection. E-cigarette users were found to have different bacteria in their mouths compared to smokers and non-smokers.
Researchers at NYU College of Dentistry discovered that excessive fluoride causes dental fluorosis by altering calcium signaling, mitochondrial function, and gene expression in tooth enamel cells. This understanding provides a promising mechanistic view of how fluorosis arises.